Uso de múltiples substancias entre hombres jóvenes

Estudios neurobiológicos tienen como hipótesis un camino final común al comportamiento adictivo en el sistema mesolímbico. La nicotina se ha mostrado como una recompensa, causando un aumento en el comportamiento de buscar drogas. Desde que hay evidencia que la nicotina, el alcohol y otras substancia...

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Fecha de publicación:: 2007

Institución:: Universidad de Caldas

Repositorio:: Repositorio Institucional U. Caldas

Idioma:: spa

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network_acronym_str	REPOUCALDA
network_name_str	Repositorio Institucional U. Caldas
repository_id_str
dc.title.none.fl_str_mv	Uso de múltiples substancias entre hombres jóvenes Multiple substance use among young males
title	Uso de múltiples substancias entre hombres jóvenes
spellingShingle	Uso de múltiples substancias entre hombres jóvenes substancias psicoactivas nicotina alcohol cannabis comportamiento psychoactive substances nicotine alcohol cannabis behavior -
title_short	Uso de múltiples substancias entre hombres jóvenes
title_full	Uso de múltiples substancias entre hombres jóvenes
title_fullStr	Uso de múltiples substancias entre hombres jóvenes
title_full_unstemmed	Uso de múltiples substancias entre hombres jóvenes
title_sort	Uso de múltiples substancias entre hombres jóvenes
dc.subject.none.fl_str_mv	substancias psicoactivas nicotina alcohol cannabis comportamiento psychoactive substances nicotine alcohol cannabis behavior -
topic	substancias psicoactivas nicotina alcohol cannabis comportamiento psychoactive substances nicotine alcohol cannabis behavior -
description	Estudios neurobiológicos tienen como hipótesis un camino final común al comportamiento adictivo en el sistema mesolímbico. La nicotina se ha mostrado como una recompensa, causando un aumento en el comportamiento de buscar drogas. Desde que hay evidencia que la nicotina, el alcohol y otras substancias psicoactivas actúan de la misma forma y parecen aumentar sus efectos en sujetos animales, el comportamiento con el uso de drogas por los humanos se ve reflejado con el aumento en el uso de personas nicótico-dependientes. Nosotros usamos marcadores biológicos de la sustancia tanto como cuestionarios para clasificar los niveles del uso de substancias psicoactivas entre jóvenes de 18 años. Encontramos que el aumento de los niveles de la dependencia de la nicotina estaba relacionado a altos niveles del abuso de alcohol. Aparte, la dependencia de altos niveles de nicotina estaban asociados a niveles elevados del uso de cannabis.
publishDate	2007
dc.date.none.fl_str_mv	2007-01-01T00:00:00Z 2007-01-01T00:00:00Z 2007-01-01 2025-10-08T21:49:14Z 2025-10-08T21:49:14Z
dc.type.none.fl_str_mv	Artículo de revista http://purl.org/coar/resource_type/c_6501 Text info:eu-repo/semantics/article Journal article info:eu-repo/semantics/publishedVersion http://purl.org/coar/version/c_970fb48d4fbd8a85
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dc.identifier.none.fl_str_mv	0122-8455 https://repositorio.ucaldas.edu.co/handle/ucaldas/25050 2590-7840 https://revistasojs.ucaldas.edu.co/index.php/culturaydroga/article/view/5492
identifier_str_mv	0122-8455 2590-7840
url	https://repositorio.ucaldas.edu.co/handle/ucaldas/25050 https://revistasojs.ucaldas.edu.co/index.php/culturaydroga/article/view/5492
dc.language.none.fl_str_mv	spa
language	spa
dc.relation.none.fl_str_mv	118 14 107 12 Cultura y Droga Adriani W, Deroche-Gamonet V, Le Moal M, Laviola G, Piazza PV. Preexposure during or following adolescence differently affects nicotine-rewarding properties in adult rats. Psychopharmacology (Berl) 2006; 184(3–4):382–90. [Feb]. Agabio R, Nioi M, Serra C, Valle P, Gessa GL. Alcohol use disorders in primary care patients in cagliari, Italy. Alcohol Alcohol 2006; 41(3):341–4 [May-Jun]. Balfour DJ, Ridley DL. The effects of nicotine on neural pathways implicated in depression: a factor in nicotine addiction? Pharmacol Biochem Behav 2000; 66 (1):79–85 [May]. Balfour DJ, Benwell ME, Birrell CE, Kelly RJ, Al-Aloul M. Sensitization of the mesoaccumbens dopamine response to nicotine. Pharmacol Biochem Behav 1998;59 (4):1021–30 [Apr]. Biederman J,MonuteauxMC,Mick E,Wilens TE, Fontanella JA, PoetzlKM, et al. Is cigarette smoking a gateway to alcohol and illicit drug use disorders?Astudy of youths with and without attention deficit hyperactivity disorder. Biol Psychiatry 2006;59 (3):258–64 [Feb 1]. Blomqvist O, Ericson M, Johnson DH, Engel JA, Soderpalm B. Voluntary ethanol intake in the rat: effects of nicotinic acetylcholine receptor blockade or sub chronic nicotine treatment. Eur J Pharmacol 1996; 314 (3):257–67 [Oct 31]. 310 N.D. Kapusta et al. / Pharmacology, Biochemistry and Behavior 86 (2007) 306–311 Bradley KA, Kivlahan DR, Bush KR, McDonell MB, Fihn SD. Variations on the CAGE alcohol screening questionnaire: strengths and limitations in VA general medical patients. Alcohol Clin Exp Res 2001; 25: 1472–8. Brody AL, Olmstead RE, London ED, Farahi J, Meyer JH, Grossman P, et al. Smoking-induced ventral striatum dopamine release. Am J Psychiatry 2004; 161: 1211–8. Centers for Disease Control and Prevention (CDC). Use of cigarettes and other tobacco products among students aged 13–15 years–worldwide, 1999–2005. MMWR Morb Mort Wkly Rep 2006; 55(20):553–6 [May 26]. Chabrol H, Niezborala M, Chastan E, de Leon J. Comparison of the Heavy Smoking Index and of the Fagerstrom Test for Nicotine Dependence in a sample of 749 cigarette smokers. Addict Behave 2005; 30(7):1474–7 [Aug]. Chambers RA, Taylor JR, Potenza MN. Developmental neuro circuitry of motivation in adolescence: a critical period of addiction vulnerability. Am J Psychiatry 2003; 160(6):1041–52 [Jun]. Chan AW, Pristach EA,Welte JW. Detection by the CAGE of alcoholism or heavy drinking in primary care outpatients and the general population. J Subst Abuse 1994; 6: 123–35. Collier DA. The genetics of cannabis involvement in humans: a genetic idemiological perspective. Addiction 2006; 101(6):780–1 [Jun]. CorrigallWA, Coen KM, Adamson KL. Self-administered nicotine activates the mesolimbic dopamine system through the ventral tegmental area. Brain Res 1994; 653 (1–2):278–84 [Aug 8]. Degenhardt L, Hall W., Lynskey M. The relationship between cannabis use and other substance use in the general population. Drug Alcohol Depend 2001; 64: 319–27. Diaz FJ, Jane M, Salto E, Pardell H, Salleras L, Pinet C, et al. A brief measure of high nicotine dependence for busy clinicians and large epidemiological surveys. Aust N Z J Psychiatry 2005; 39 (3):161–8 [Mar]. Ewing J. A. Detecting alcoholism. The CAGE questionnaire. JAMA 1984; 252: 1905–7. Fagerstrom KO, Schneider NG. Measuring nicotine dependence: a review of the Fagerstrom Tolerance Questionnaire. J. Behav Med 1989; 12(2):159–82 [Apr]. Heatherton TF, Kozlowski LT, Frecker RC, Rickert W. Robinson J. Measuring the heaviness of smoking: using self-reported time to the first cigarette of the day and number of cigarettes smoked per day. Br. J. Addict 1989; 84: 791–9. Heatherton TF, Kozlowski LT, Frecker RC, Fagerstrom KO. The Fagerstrom Test for Nicotine Dependence: a revision of the Fagerstrom Tolerance Questionnaire. Br J Addict 1991; 86:1119–27. Hofler M, Lieb R, Perkonigg A, Schuster P, Sonntag H, Wittchen HU. Covariates of cannabis use progression in a representative population sample of adolescents: a prospective examination of vulnerability and risk factors. Addiction 1999; 94(11):1679–94 [Nov]. Iyaniwura T. T. Wright AE, Balfour DJ. Evidence that mesoaccumbens dopamine and locomotor responses to nicotine in the rat are influenced by pretreatment dose and strain. Psychopharmacology (Berl) 2001; 158(1):73–9 [Oct]. John U, Meyer C, Rumpf HJ, Hapke U. Probabilities of alcohol high-risk drinking, abuse or dependence estimated on grounds of tobacco smoking and nicotine dependence. Addiction 2003; 98:805–14. Kelley BM, Rowan JD. Long-term, low-level adolescent nicotine exposure produces dose-dependent changes in cocaine sensitivity and reward in adult mice. Int J Dev Neurosci 2004; 22(5–6):339–48 [Aug-Oct]. Kozlowski LT, Porter CQ, Orleans CT, Pope MA, Heatherton T. Predicting smoking cessation with self-reported measures of nicotine dependence: FTQ, FTND, and HSI. Drug Alcohol Depend 1994; 34(3):211–6 [Feb]. Kunin D, Smith BR, Amit Z. Nicotine and ethanol interaction on conditioned taste aversions induced by both drugs. Pharmacol Biochem Behav 1999; 62 (2):215–21 [Feb]. Levin ED., Rezvani, A. H., Montoya D., Rose JE, Swartzwelder HS. Adolescent onset nicotine self-administration modeled in female rats. Psychopharmacology (Berl) 2003; 169(2):141–9 [Sep]. Lingford-Hughes A, Nutt D. Neurobiology of addiction and implications for treatment. Br J. Psychiatry 2003; 182:97–100 [Feb]. Liskow B., Campbell J., Nickel EJ. Powell BJ. Validity of the CAGE questionnaire in screening for alcohol dependence in a walk-in (triage) clinic. J. Stud Alcohol 1995; 56:277–81. Low EC, Ong MC, TanM. Breath carbon monoxide as an indication of smoking habit in the military setting. Singap Med J 2004; 45 (12):578–82 [Dec]. Maldonado G, Greenland S. Estimating causal effects. Int J Epidemiol 2002; 31 (2):422–9 [Apr]. Malet L, Schwan R, Boussiron D, Aublet-Cuvelier B, Llorca PM. Validity of the CAGE questionnaire in hospital. Eur Psychiatry 2005; 20(7):484–9 [Nov]. Manzanares J, Ortiz S, Oliva JM, Perez-Rial S, Palomo T. Interactions between cannabinoid and opioid receptor systems in the mediation of ethanol effects. Alcohol Alcohol 2005; 40(1):25–34 [Jan-Feb]. Merrill JC, Kleber HD, Shwartz M, Liu H, Lewis SR. Cigarettes, alcohol, marijuana, other risk behaviors, and American youth. Drug and Alcohol Depend 1999; 56:205–12. Nestler EJ. Is there a common molecular pathway for addiction? Nat Neurosci 2005; 8(11):1445–9 [Nov]. O’dell LE, Bruijnzeel AW, Smith RT, Parsons LH, Merves ML, Goldberger BA, et al. Diminished nicotine withdrawal in adolescent rats: implications for vulnerability to addiction. Psychopharmacology (Berl) 2006; 186(4):612–9 [Jul]. Pontieri FE, Tanda G, Orzi F, Di Chiara G. Effects of nicotine on the nucleus accumbens and similarity to those of addictive drugs. Nature 1996; 382 (6588):255–7 [Jul 18]. Richter KP, Ahluwalia HK, Mosier MC, Nazir N, Ahluwalia JS. A population based study of cigarette smoking among illicit drug users in the United States. Addiction 2002; 97(7):861–9 [Jul]. Robinson TE, Berridge KC. Incentive-sensitization and addiction. Addiction 2001; 96(1):103–14 [Jan]. Saremi A, Hanson RL, Williams DE, Roumain J, Robin RW, Long JC, et al. Validity of the CAGE questionnaire in an American Indian population. J Stud Alcohol 2001; 62:294–300. Savola O, Niemela O, Hillbom M. Blood alcohol is the best indicator of hazardous alcohol drinking in young adults and working-age patients with trauma. Alcohol 2004; 39(4):340–5 [Jul-Aug]. Sutherland I, Willner P. Patterns of alcohol, cigarette and illicit drug use in English adolescents. Addiction 1998; 93:1199–208. The Plinius Mayor society. Guidelines on evaluation of treatment of alcohol dependence. Alcoholism: Journal on alcoholism and related addictions, vol. XXX. 1994. Supplement. Núm. 14 , Año 2007 : Enero - Diciembre https://revistasojs.ucaldas.edu.co/index.php/culturaydroga/article/download/5492/4960
dc.rights.none.fl_str_mv	Revista Cultura y Droga - 2007 https://creativecommons.org/licenses/by-nc-sa/4.0/ info:eu-repo/semantics/openAccess http://purl.org/coar/access_right/c_abf2
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dc.publisher.none.fl_str_mv	Universidad de Caldas
publisher.none.fl_str_mv	Universidad de Caldas
dc.source.none.fl_str_mv	https://revistasojs.ucaldas.edu.co/index.php/culturaydroga/article/view/5492
institution	Universidad de Caldas
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spelling	Uso de múltiples substancias entre hombres jóvenesMultiple substance use among young malessubstancias psicoactivasnicotinaalcoholcannabiscomportamientopsychoactive substancesnicotinealcoholcannabisbehavior-Estudios neurobiológicos tienen como hipótesis un camino final común al comportamiento adictivo en el sistema mesolímbico. La nicotina se ha mostrado como una recompensa, causando un aumento en el comportamiento de buscar drogas. Desde que hay evidencia que la nicotina, el alcohol y otras substancias psicoactivas actúan de la misma forma y parecen aumentar sus efectos en sujetos animales, el comportamiento con el uso de drogas por los humanos se ve reflejado con el aumento en el uso de personas nicótico-dependientes. Nosotros usamos marcadores biológicos de la sustancia tanto como cuestionarios para clasificar los niveles del uso de substancias psicoactivas entre jóvenes de 18 años. Encontramos que el aumento de los niveles de la dependencia de la nicotina estaba relacionado a altos niveles del abuso de alcohol. Aparte, la dependencia de altos niveles de nicotina estaban asociados a niveles elevados del uso de cannabis.Neurobiological studies take addictive behavior in the mesolimbic system as a common final position. Nicotine has been shown as a reward, causing an increase in drug-seeking behavior. Since the rise of evidence that nicotine, alcohol and other psychoactive substances act in the same manner and seem to increase their impact on animals, behavior with drug use by humans is reflected in the increase of the use of nicotine-dependent persons. Biological markers of the substance were used, as well as questionnaires to rank levels of psychoactive substance use among youths 18 years of age. The increased levels of nicotine dependence were linked to high levels of alcohol abuse. In addition, dependence on high levels of nicotine was associated with high levels of cannabis use.Universidad de Caldas2007-01-01T00:00:00Z2025-10-08T21:49:14Z2007-01-01T00:00:00Z2025-10-08T21:49:14Z2007-01-01Artículo de revistahttp://purl.org/coar/resource_type/c_6501Textinfo:eu-repo/semantics/articleJournal articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_2df8fbb1application/pdf0122-8455https://repositorio.ucaldas.edu.co/handle/ucaldas/250502590-7840https://revistasojs.ucaldas.edu.co/index.php/culturaydroga/article/view/5492https://revistasojs.ucaldas.edu.co/index.php/culturaydroga/article/view/5492spa1181410712Cultura y DrogaAdriani W, Deroche-Gamonet V, Le Moal M, Laviola G, Piazza PV. Preexposure during or following adolescence differently affects nicotine-rewarding properties in adult rats. Psychopharmacology (Berl) 2006; 184(3–4):382–90. [Feb].Agabio R, Nioi M, Serra C, Valle P, Gessa GL. Alcohol use disorders in primary care patients in cagliari, Italy. Alcohol Alcohol 2006; 41(3):341–4 [May-Jun].Balfour DJ, Ridley DL. The effects of nicotine on neural pathways implicated in depression: a factor in nicotine addiction? Pharmacol Biochem Behav 2000; 66 (1):79–85 [May].Balfour DJ, Benwell ME, Birrell CE, Kelly RJ, Al-Aloul M. Sensitization of the mesoaccumbens dopamine response to nicotine. Pharmacol Biochem Behav 1998;59 (4):1021–30 [Apr].Biederman J,MonuteauxMC,Mick E,Wilens TE, Fontanella JA, PoetzlKM, et al. Is cigarette smoking a gateway to alcohol and illicit drug use disorders?Astudy of youths with and without attention deficit hyperactivity disorder. Biol Psychiatry 2006;59 (3):258–64 [Feb 1].Blomqvist O, Ericson M, Johnson DH, Engel JA, Soderpalm B. Voluntary ethanol intake in the rat: effects of nicotinic acetylcholine receptor blockade or sub chronic nicotine treatment. Eur J Pharmacol 1996; 314 (3):257–67 [Oct 31].310 N.D. Kapusta et al. / Pharmacology, Biochemistry and Behavior 86 (2007) 306–311Bradley KA, Kivlahan DR, Bush KR, McDonell MB, Fihn SD. Variations on the CAGE alcohol screening questionnaire: strengths and limitations in VA general medical patients. Alcohol Clin Exp Res 2001; 25: 1472–8.Brody AL, Olmstead RE, London ED, Farahi J, Meyer JH, Grossman P, et al. Smoking-induced ventral striatum dopamine release. Am J Psychiatry 2004; 161: 1211–8.Centers for Disease Control and Prevention (CDC). Use of cigarettes and other tobacco products among students aged 13–15 years–worldwide, 1999–2005. MMWR Morb Mort Wkly Rep 2006; 55(20):553–6 [May 26].Chabrol H, Niezborala M, Chastan E, de Leon J. Comparison of the Heavy Smoking Index and of the Fagerstrom Test for Nicotine Dependence in a sample of 749 cigarette smokers. Addict Behave 2005; 30(7):1474–7 [Aug].Chambers RA, Taylor JR, Potenza MN. Developmental neuro circuitry of motivation in adolescence: a critical period of addiction vulnerability. Am J Psychiatry 2003; 160(6):1041–52 [Jun].Chan AW, Pristach EA,Welte JW. Detection by the CAGE of alcoholism or heavy drinking in primary care outpatients and the general population. J Subst Abuse 1994; 6: 123–35.Collier DA. The genetics of cannabis involvement in humans: a genetic idemiological perspective. Addiction 2006; 101(6):780–1 [Jun].CorrigallWA, Coen KM, Adamson KL. Self-administered nicotine activates the mesolimbic dopamine system through the ventral tegmental area. Brain Res 1994; 653 (1–2):278–84 [Aug 8].Degenhardt L, Hall W., Lynskey M. The relationship between cannabis use and other substance use in the general population. Drug Alcohol Depend 2001; 64: 319–27.Diaz FJ, Jane M, Salto E, Pardell H, Salleras L, Pinet C, et al. A brief measure of high nicotine dependence for busy clinicians and large epidemiological surveys. Aust N Z J Psychiatry 2005; 39 (3):161–8 [Mar].Ewing J. A. Detecting alcoholism. The CAGE questionnaire. JAMA 1984; 252: 1905–7. Fagerstrom KO, Schneider NG. Measuring nicotine dependence: a review of the Fagerstrom Tolerance Questionnaire. J. Behav Med 1989; 12(2):159–82 [Apr].Heatherton TF, Kozlowski LT, Frecker RC, Rickert W. Robinson J. Measuring the heaviness of smoking: using self-reported time to the first cigarette of the day and number of cigarettes smoked per day. Br. J. Addict 1989; 84: 791–9.Heatherton TF, Kozlowski LT, Frecker RC, Fagerstrom KO. The Fagerstrom Test for Nicotine Dependence: a revision of the Fagerstrom Tolerance Questionnaire. Br J Addict 1991; 86:1119–27.Hofler M, Lieb R, Perkonigg A, Schuster P, Sonntag H, Wittchen HU. Covariates of cannabis use progression in a representative population sample of adolescents: a prospective examination of vulnerability and risk factors. Addiction 1999; 94(11):1679–94 [Nov].Iyaniwura T. T. Wright AE, Balfour DJ. Evidence that mesoaccumbens dopamine and locomotor responses to nicotine in the rat are influenced by pretreatment dose and strain. Psychopharmacology (Berl) 2001; 158(1):73–9 [Oct].John U, Meyer C, Rumpf HJ, Hapke U. Probabilities of alcohol high-risk drinking, abuse or dependence estimated on grounds of tobacco smoking and nicotine dependence. Addiction 2003; 98:805–14.Kelley BM, Rowan JD. Long-term, low-level adolescent nicotine exposure produces dose-dependent changes in cocaine sensitivity and reward in adult mice. Int J Dev Neurosci 2004; 22(5–6):339–48 [Aug-Oct].Kozlowski LT, Porter CQ, Orleans CT, Pope MA, Heatherton T. Predicting smoking cessation with self-reported measures of nicotine dependence: FTQ, FTND, and HSI. Drug Alcohol Depend 1994; 34(3):211–6 [Feb].Kunin D, Smith BR, Amit Z. Nicotine and ethanol interaction on conditioned taste aversions induced by both drugs. Pharmacol Biochem Behav 1999; 62 (2):215–21 [Feb].Levin ED., Rezvani, A. H., Montoya D., Rose JE, Swartzwelder HS. Adolescent onset nicotine self-administration modeled in female rats. Psychopharmacology (Berl) 2003; 169(2):141–9 [Sep].Lingford-Hughes A, Nutt D. Neurobiology of addiction and implications for treatment. Br J. Psychiatry 2003; 182:97–100 [Feb].Liskow B., Campbell J., Nickel EJ. Powell BJ. Validity of the CAGE questionnaire in screening for alcohol dependence in a walk-in (triage) clinic. J. Stud Alcohol 1995; 56:277–81.Low EC, Ong MC, TanM. Breath carbon monoxide as an indication of smoking habit in the military setting. Singap Med J 2004; 45 (12):578–82 [Dec].Maldonado G, Greenland S. Estimating causal effects. Int J Epidemiol 2002; 31 (2):422–9 [Apr].Malet L, Schwan R, Boussiron D, Aublet-Cuvelier B, Llorca PM. Validity of the CAGE questionnaire in hospital. Eur Psychiatry 2005; 20(7):484–9 [Nov].Manzanares J, Ortiz S, Oliva JM, Perez-Rial S, Palomo T. Interactions between cannabinoid and opioid receptor systems in the mediation of ethanol effects. Alcohol Alcohol 2005; 40(1):25–34 [Jan-Feb].Merrill JC, Kleber HD, Shwartz M, Liu H, Lewis SR. Cigarettes, alcohol, marijuana, other risk behaviors, and American youth. Drug and Alcohol Depend 1999; 56:205–12.Nestler EJ. Is there a common molecular pathway for addiction? Nat Neurosci 2005; 8(11):1445–9 [Nov].O’dell LE, Bruijnzeel AW, Smith RT, Parsons LH, Merves ML, Goldberger BA, et al. Diminished nicotine withdrawal in adolescent rats: implications for vulnerability to addiction. Psychopharmacology (Berl) 2006; 186(4):612–9 [Jul].Pontieri FE, Tanda G, Orzi F, Di Chiara G. Effects of nicotine on the nucleus accumbens and similarity to those of addictive drugs. Nature 1996; 382 (6588):255–7 [Jul 18].Richter KP, Ahluwalia HK, Mosier MC, Nazir N, Ahluwalia JS. A population based study of cigarette smoking among illicit drug users in the United States. Addiction 2002; 97(7):861–9 [Jul].Robinson TE, Berridge KC. Incentive-sensitization and addiction. Addiction 2001; 96(1):103–14 [Jan].Saremi A, Hanson RL, Williams DE, Roumain J, Robin RW, Long JC, et al. Validity of the CAGE questionnaire in an American Indian population. J Stud Alcohol 2001; 62:294–300.Savola O, Niemela O, Hillbom M. Blood alcohol is the best indicator of hazardous alcohol drinking in young adults and working-age patients with trauma. Alcohol 2004; 39(4):340–5 [Jul-Aug].Sutherland I, Willner P. Patterns of alcohol, cigarette and illicit drug use in English adolescents. Addiction 1998; 93:1199–208.The Plinius Mayor society. Guidelines on evaluation of treatment of alcohol dependence. Alcoholism: Journal on alcoholism and related addictions, vol. XXX. 1994. Supplement.Núm. 14 , Año 2007 : Enero - Diciembrehttps://revistasojs.ucaldas.edu.co/index.php/culturaydroga/article/download/5492/4960Revista Cultura y Droga - 2007https://creativecommons.org/licenses/by-nc-sa/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Arango, Catalina Maríaoai:repositorio.ucaldas.edu.co:ucaldas/250502025-10-08T21:49:14Z

Uso de múltiples substancias entre hombres jóvenes

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