A review on computational fluid dynamics modelling in human thoracic aorta

It has long been recognized that the forces and stresses produced by the blood flow on the walls of the cardiovascular system are central to the development of different cardiovascular diseases. However, up to now, the reason why arterial diseases occur at preferential sites is still not fully under...

Full description

Autores:
Laín Beatove, Santiago
Caballero Gaviria, Andrés David
Tipo de recurso:
Article of journal
Fecha de publicación:
2013
Institución:
Universidad Autónoma de Occidente
Repositorio:
RED: Repositorio Educativo Digital UAO
Idioma:
eng
OAI Identifier:
oai:red.uao.edu.co:10614/11806
Acceso en línea:
http://red.uao.edu.co//handle/10614/11806
Palabra clave:
Aorta, Thoracic
Flujo sanguíneo
Hemodinámica
Blood flow
Hemodynamics
Blood flow
Computational fluid dynamics
Hemodynamics
Human thoracic aorta
Rights
openAccess
License
Derechos Reservados - Universidad Autónoma de Occidente
Description
Summary:It has long been recognized that the forces and stresses produced by the blood flow on the walls of the cardiovascular system are central to the development of different cardiovascular diseases. However, up to now, the reason why arterial diseases occur at preferential sites is still not fully understood. This paper reviews the progress, made largely within the last decade, towards the use of 3D computational fluid dynamics (CFD) models to simulate the blood flow dynamics and its interaction with the arterial wall within the human thoracic aorta (TA). We describe the technical aspects of model building, review methods to create anatomic and physiologic models, obtain material properties, assign boundary conditions, solve the equations governing blood flow , and describe the assumptions used in running the simulations. Detailed comparative information is provided in tabular format about the model setup, simulation results, and a summary of the major insights and contributions of each TA article reviewed. Several syntheses are given that summarize the research carried out by influential research groups, review important findings, discuss the methods employed, limitations, and opportunities for further research. We hope that this review will stimulate computational research that will contribute to the continued improvement of cardiovascular health through a strong interaction and cooperation between engineers and clinicians