In vivo swine kidney viscoelasticity during acute gradual decrease in renal blood flow: pilot study
Elasticity imaging methods have been used to study kidney mechanical properties and have demonstrated that the kidney elastic modulus increases with disease state. However, studies in swine suggest that kidney elastic modulus is also affected by hemodynamic variables. A newly emerging method called...
- Autores:
-
Amador, C. (Carolina)
Urban, M. (Matthew)
Kinnick, R. (Randall)
Greenleaf, J. (James)
Shigao Chen
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2013
- Institución:
- Universidad EIA .
- Repositorio:
- Repositorio EIA .
- Idioma:
- eng
- OAI Identifier:
- oai:repository.eia.edu.co:11190/521
- Acceso en línea:
- https://repository.eia.edu.co/handle/11190/521
- Palabra clave:
- RBI00111
TECNOLOGÍAS PARA LA SALUD
TECHNOLOGY IN HEALTH
KIDNEY - PHYSIOLOGY
RIÑÓN - FISIOLOGÍA
RENAL CORTEX
CORTEZA RENAL
- Rights
- openAccess
- License
- Derechos Reservados - Universidad EIA, 2020
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| dc.title.spa.fl_str_mv |
In vivo swine kidney viscoelasticity during acute gradual decrease in renal blood flow: pilot study |
| dc.title.alternative.spa.fl_str_mv |
Viscoelasticidad renal durante la disminución gradual de flujo sanguíneo en un modelo porcino in vivo: estudio piloto |
| title |
In vivo swine kidney viscoelasticity during acute gradual decrease in renal blood flow: pilot study |
| spellingShingle |
In vivo swine kidney viscoelasticity during acute gradual decrease in renal blood flow: pilot study RBI00111 TECNOLOGÍAS PARA LA SALUD TECHNOLOGY IN HEALTH KIDNEY - PHYSIOLOGY RIÑÓN - FISIOLOGÍA RENAL CORTEX CORTEZA RENAL |
| title_short |
In vivo swine kidney viscoelasticity during acute gradual decrease in renal blood flow: pilot study |
| title_full |
In vivo swine kidney viscoelasticity during acute gradual decrease in renal blood flow: pilot study |
| title_fullStr |
In vivo swine kidney viscoelasticity during acute gradual decrease in renal blood flow: pilot study |
| title_full_unstemmed |
In vivo swine kidney viscoelasticity during acute gradual decrease in renal blood flow: pilot study |
| title_sort |
In vivo swine kidney viscoelasticity during acute gradual decrease in renal blood flow: pilot study |
| dc.creator.fl_str_mv |
Amador, C. (Carolina) Urban, M. (Matthew) Kinnick, R. (Randall) Greenleaf, J. (James) Shigao Chen |
| dc.contributor.author.spa.fl_str_mv |
Amador, C. (Carolina) Urban, M. (Matthew) Kinnick, R. (Randall) Greenleaf, J. (James) Shigao Chen |
| dc.subject.lcsh.spa.fl_str_mv |
RBI00111 |
| topic |
RBI00111 TECNOLOGÍAS PARA LA SALUD TECHNOLOGY IN HEALTH KIDNEY - PHYSIOLOGY RIÑÓN - FISIOLOGÍA RENAL CORTEX CORTEZA RENAL |
| dc.subject.eia.spa.fl_str_mv |
TECNOLOGÍAS PARA LA SALUD TECHNOLOGY IN HEALTH |
| dc.subject.eurovoc.spa.fl_str_mv |
KIDNEY - PHYSIOLOGY RIÑÓN - FISIOLOGÍA |
| dc.subject.keywords.spa.fl_str_mv |
RENAL CORTEX CORTEZA RENAL |
| description |
Elasticity imaging methods have been used to study kidney mechanical properties and have demonstrated that the kidney elastic modulus increases with disease state. However, studies in swine suggest that kidney elastic modulus is also affected by hemodynamic variables. A newly emerging method called Shearwave Dispersion Ultrasound Vibrometry (SDUV) offers a tool to determine renal elasticity and viscosity in vivo. The purpose of this study was directed toward evaluating the feasibility of SDUV for in vivo measurements of healthy swine kidney during acute gradual decease of renal blood flow. In this study in vivo SDUV measurements were made on a group of 5 normal swine kidneys at baseline renal blood flow (RBF) and 25, 50, 75 and 100% decrease in RBF. The shear elastic modulus at full baseline was 7.04 ± 0.92 kPa and 3.48 ± 0.20 kPa at 100% decrease in RBF. The viscosity did not change between baseline (2.23 ± 0.33 Pa•s) and 100% decrease in RBF (2.03 ± 0.32 Pa•s). The data from this study indicates that other variables such as local blood flow, pressure and volume as well as method accuracy need to be measured to illustrate the relationship between shear elasticity and viscosity associated with acute kidney processes. |
| publishDate |
2013 |
| dc.date.created.spa.fl_str_mv |
2013-06 |
| dc.date.submitted.spa.fl_str_mv |
2013-05-02 |
| dc.date.accepted.spa.fl_str_mv |
2013-05-28 |
| dc.date.accessioned.spa.fl_str_mv |
2014-05-06T00:01:11Z |
| dc.date.available.spa.fl_str_mv |
2014-05-06T00:01:11Z |
| dc.date.issued.spa.fl_str_mv |
2014-05-05 |
| dc.type.spa.fl_str_mv |
Artículo de revista |
| dc.type.coar.fl_str_mv |
http://purl.org/coar/resource_type/c_2df8fbb1 |
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http://purl.org/coar/resource_type/c_6501 |
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info:eu-repo/semantics/article |
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info:eu-repo/semantics/publishedVersion |
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Text |
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https://purl.org/redcol/resource_type/ART |
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http://purl.org/coar/version/c_970fb48d4fbd8a85 |
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publishedVersion |
| dc.identifier.issn.spa.fl_str_mv |
ISSN 19099762 |
| dc.identifier.uri.spa.fl_str_mv |
https://repository.eia.edu.co/handle/11190/521 |
| dc.identifier.bibliographiccitation.spa.fl_str_mv |
Amador, C., Urban, M., Kinnick, R., Shigao Chen and Greenleaf, J. In vivo swine kidney viscoelasticity during acute gradual decrease in renal blood flow: pilot study, Revista Ingeniería Biomédica, 7 (13), 68-78. doi: http://repository. eia.edu.co/handle/11190/521 |
| identifier_str_mv |
ISSN 19099762 Amador, C., Urban, M., Kinnick, R., Shigao Chen and Greenleaf, J. In vivo swine kidney viscoelasticity during acute gradual decrease in renal blood flow: pilot study, Revista Ingeniería Biomédica, 7 (13), 68-78. doi: http://repository. eia.edu.co/handle/11190/521 |
| url |
https://repository.eia.edu.co/handle/11190/521 |
| dc.language.iso.spa.fl_str_mv |
eng |
| language |
eng |
| dc.relation.references.spa.fl_str_mv |
Y. H. Liu, "Renal fibrosis: New insights into the pathogenesis and therapeutics," Kidney International, 69, 213-217, January 2006. Y. Fung, Biomechanics: mechanical properties of living tissues: Springer-Verlag, 1993. D. Alleyne and P. Cawley, "A two-dimensional Fourier transform method for the measurement of propagating multimode signals," The Journal of the Acoustical Society of America, 89, 1159-1168, 1991. |
| dc.rights.spa.fl_str_mv |
Derechos Reservados - Universidad EIA, 2020 |
| dc.rights.uri.spa.fl_str_mv |
https://creativecommons.org/licenses/by-nc/4.0/ |
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info:eu-repo/semantics/openAccess |
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Atribución-NoComercial |
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http://purl.org/coar/access_right/c_abf2 |
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Derechos Reservados - Universidad EIA, 2020 https://creativecommons.org/licenses/by-nc/4.0/ Atribución-NoComercial http://purl.org/coar/access_right/c_abf2 |
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openAccess |
| dc.format.extent.spa.fl_str_mv |
11 p. |
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application/pdf |
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Biomédica, Mecatrónica y Mecánica |
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Escuela de Ingeniería de Antioquia EIA Universidad CES |
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Universidad EIA . |
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Amador, C. (Carolina)4637afcdd8df905c76640d37a6f14fb8-1Urban, M. (Matthew)2b28ac701f53ad63a8fd72b6dfb67037-1Kinnick, R. (Randall)733be96f9549ab984ada5e68dac3deba-1Greenleaf, J. (James)7fdbd6f5000356ab3c6bbfda4dad8d21-1Shigao Chend330abc2cc1c899b852e6c918d270239-1amadorcarrascal.carolina@mayo.edu2014-05-06T00:01:11Z2014-05-06T00:01:11Z2013-062014-05-052013-05-022013-05-28ISSN 19099762https://repository.eia.edu.co/handle/11190/521Amador, C., Urban, M., Kinnick, R., Shigao Chen and Greenleaf, J. In vivo swine kidney viscoelasticity during acute gradual decrease in renal blood flow: pilot study, Revista Ingeniería Biomédica, 7 (13), 68-78. doi: http://repository. eia.edu.co/handle/11190/521Elasticity imaging methods have been used to study kidney mechanical properties and have demonstrated that the kidney elastic modulus increases with disease state. However, studies in swine suggest that kidney elastic modulus is also affected by hemodynamic variables. A newly emerging method called Shearwave Dispersion Ultrasound Vibrometry (SDUV) offers a tool to determine renal elasticity and viscosity in vivo. The purpose of this study was directed toward evaluating the feasibility of SDUV for in vivo measurements of healthy swine kidney during acute gradual decease of renal blood flow. In this study in vivo SDUV measurements were made on a group of 5 normal swine kidneys at baseline renal blood flow (RBF) and 25, 50, 75 and 100% decrease in RBF. The shear elastic modulus at full baseline was 7.04 ± 0.92 kPa and 3.48 ± 0.20 kPa at 100% decrease in RBF. The viscosity did not change between baseline (2.23 ± 0.33 Pa•s) and 100% decrease in RBF (2.03 ± 0.32 Pa•s). The data from this study indicates that other variables such as local blood flow, pressure and volume as well as method accuracy need to be measured to illustrate the relationship between shear elasticity and viscosity associated with acute kidney processes.Métodos de imágenes de elasticidad se han utilizado para estudiar las propiedades mecánicas renales y han demostrado que el módulo elástico de los riñones del aumenta con el estado de enfermedades renales. Sin embargo, estudios en cerdos sugieren que el riñón módulo elástico también se ve afectada por las variables hemodinámicas. Un método emergente llamado Shearwave Dispersion Ultrasound Vibrometry (SDUV) ofrece una herramienta para determinar la elasticidad y la viscosidad renal. El propósito de este estudio se dirige a la evaluación de la viabilidad de SDUV para mediciones las propiedades viscoelasticas del riñón saludable durante variación aguda del flujo sanguíneo renal. En este estudio el método SDUV se realizó en un grupo de 5 riñones porcinos normales al inicio del flujo sanguíneo renal (RBF) basal y 25, 50, 75 y 100% de disminución en el RBF. El módulo elástico basal fue de 7,04 ± 0,92 kPa y 3,48 ± 0,20 kPa a 100% de disminución del RBF. La viscosidad no cambió entre el momento basal (2,23 ± 0,33 Pa • s) y el 100% de disminución del RBF (2,03 ± 0,32 Pa • s). Los datos de este estudio indican que variables tales como el flujo local de sangre, la presión y el volumen así como el método exactitud deben ser medidos para ilustrar la relación entre la elasticidad y la viscosidad asociada con los procesos renales agudos.11 p.application/pdfengDerechos Reservados - Universidad EIA, 2020https://creativecommons.org/licenses/by-nc/4.0/El autor de la obra, actuando en nombre propio, hace entrega del ejemplar respectivo y de sus anexos en formato digital o electrónico y autoriza a la ESCUELA DE INGENIERIA DE ANTIOQUIA, para que en los términos establecidos en la Ley 23 de 1982, Ley 44 de 1993, Decisión andina 351 de 1993, Decreto 460 de 1995, y demás normas generales sobre la materia, utilice y use por cualquier medio conocido o por conocer, los derechos patrimoniales de reproducción, comunicación pública, transformación y distribución de la obra objeto del presente documento. PARÁGRAFO: La presente autorización se hace extensiva no sólo a las dependencias y derechos de uso sobre la obra en formato o soporte material, sino también para formato virtual, electrónico, digital, y en red, internet, extranet, intranet, etc., y en general en cualquier formato conocido o por conocer. EL AUTOR, manifiesta que la obra objeto de la presente autorización es original y la realiza sin violar o usurpar derechos de autor de terceros, por lo tanto la obra es de exclusiva autoría y tiene la titularidad sobre la misma. PARÁGRAFO: En caso de presentarse cualquier reclamación o acción por parte de un tercero en cuanto a los derechos de autor sobre la obra en cuestión, EL AUTOR, asumirá toda la responsabilidad, y saldrá en defensa de los derechos aquí autorizados; para todos los efectos la ESCUELA DE INGENIERÍA DE ANTIOQUIA actúa como un tercero de buena fe.info:eu-repo/semantics/openAccessAtribución-NoComercialhttp://purl.org/coar/access_right/c_abf2RBI00111TECNOLOGÍAS PARA LA SALUDTECHNOLOGY IN HEALTHKIDNEY - PHYSIOLOGYRIÑÓN - FISIOLOGÍARENAL CORTEXCORTEZA RENALIn vivo swine kidney viscoelasticity during acute gradual decrease in renal blood flow: pilot studyViscoelasticidad renal durante la disminución gradual de flujo sanguíneo en un modelo porcino in vivo: estudio pilotoArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionTexthttps://purl.org/redcol/resource_type/ARThttp://purl.org/coar/version/c_970fb48d4fbd8a85Biomédica, Mecatrónica y MecánicaEscuela de Ingeniería de Antioquia EIAUniversidad CESY. H. Liu, "Renal fibrosis: New insights into the pathogenesis and therapeutics," Kidney International, 69, 213-217, January 2006.Y. Fung, Biomechanics: mechanical properties of living tissues: Springer-Verlag, 1993.D. Alleyne and P. Cawley, "A two-dimensional Fourier transform method for the measurement of propagating multimode signals," The Journal of the Acoustical Society of America, 89, 1159-1168, 1991.PublicationTHUMBNAILRBI00111.pdf.jpgRBI00111.pdf.jpgGenerated Thumbnailimage/jpeg13832https://repository.eia.edu.co/bitstreams/26a557ab-e6fc-4190-9df8-ff079ab706a0/download81aac8947eb37f43605ba640bf0710cbMD57ORIGINALRBI00111.pdfRBI00111.pdfapplication/pdf1905845https://repository.eia.edu.co/bitstreams/0ebf88ef-9b9d-49a3-8822-5d94b4c95bd9/download2a26fcc65225078ed85a3dc032cb94daMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81494https://repository.eia.edu.co/bitstreams/352b56f8-6726-4f2f-998e-bb17ed281ebd/download66874b0b9366b748c60895d2fb6339f8MD52CC-LICENSElicense_urllicense_urltext/plain; charset=utf-849https://repository.eia.edu.co/bitstreams/1601f08b-fb09-4e8b-b493-494807b059cc/download4afdbb8c545fd630ea7db775da747b2fMD53license_textlicense_texttext/html; charset=utf-821310https://repository.eia.edu.co/bitstreams/781752e3-07c8-47ae-af0e-61e55f5f0923/download10a9da7597c333616da297895d0393ecMD54license_rdflicense_rdfapplication/rdf+xml; charset=utf-823253https://repository.eia.edu.co/bitstreams/acce178e-6067-472e-87cc-eb4782c4177f/downloadcd76e7886171c964e259dcf5e912e299MD55TEXTRBI00111.pdf.txtRBI00111.pdf.txtExtracted texttext/plain38972https://repository.eia.edu.co/bitstreams/8abe8009-72f1-4181-a680-4b5399196027/download375479df1f038602add9dc349612addbMD5611190/521oai:repository.eia.edu.co:11190/5212023-07-25 16:46:06.038https://creativecommons.org/licenses/by-nc/4.0/Derechos Reservados - Universidad EIA, 2020open.accesshttps://repository.eia.edu.coRepositorio Institucional Universidad EIAbdigital@metabiblioteca.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 |