Epigenetic mechanisms and posttranslational Modifications in systemic lupus erythematosus

The complex physiology of eukaryotic cells is regulated through numerous mechanisms, including epigenetic changes and posttranslational modifications. The wide-ranging diversity of these mechanisms constitutes a way of dynamic regulation of the functionality of proteins, their activity, and their su...

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Autores:
Navarro Quiroz, Elkin
Chavez-Estrada, Valeria
Macias-Ochoa, Karime
Ayala-Navarro, María Fernanda
Flores-Aguilar, Aniyensy Sarai
Morales Navarrete, Francisco
de la Cruz Lopez, Fernando
GOMEZ ESCORCIA, LORENA
Musso, Carlos
Aroca Martínez, Gustavo
Gonzales Torres, Henry
Díaz Pérez, Anderson
Cadena Bonfanti, Andres Angélo
Sarmiento Gutiérrez, Joany
Meza, Jainy
Diaz Arroyo, Esperanza
Bello-Lemus, Yesit
Ahmad, Mostapha
Navarro Quiroz, Roberto
Tipo de recurso:
Article of journal
Fecha de publicación:
2019
Institución:
Corporación Universidad de la Costa
Repositorio:
REDICUC - Repositorio CUC
Idioma:
eng
OAI Identifier:
oai:repositorio.cuc.edu.co:11323/6084
Acceso en línea:
https://hdl.handle.net/11323/6084
https://repositorio.cuc.edu.co/
Palabra clave:
Posttranslational modifications
Epigenetic mechanisms
Systemic lupus erythematosus
Ubiquitination
SUMOylation
Glycosylation
Hydroxylation
Phosphorylation
Sulfation
Acetylation
Rights
openAccess
License
CC0 1.0 Universal
id RCUC2_fc075bb8c934a4e35ceaf628850cdf8b
oai_identifier_str oai:repositorio.cuc.edu.co:11323/6084
network_acronym_str RCUC2
network_name_str REDICUC - Repositorio CUC
repository_id_str
dc.title.spa.fl_str_mv Epigenetic mechanisms and posttranslational Modifications in systemic lupus erythematosus
title Epigenetic mechanisms and posttranslational Modifications in systemic lupus erythematosus
spellingShingle Epigenetic mechanisms and posttranslational Modifications in systemic lupus erythematosus
Posttranslational modifications
Epigenetic mechanisms
Systemic lupus erythematosus
Ubiquitination
SUMOylation
Glycosylation
Hydroxylation
Phosphorylation
Sulfation
Acetylation
title_short Epigenetic mechanisms and posttranslational Modifications in systemic lupus erythematosus
title_full Epigenetic mechanisms and posttranslational Modifications in systemic lupus erythematosus
title_fullStr Epigenetic mechanisms and posttranslational Modifications in systemic lupus erythematosus
title_full_unstemmed Epigenetic mechanisms and posttranslational Modifications in systemic lupus erythematosus
title_sort Epigenetic mechanisms and posttranslational Modifications in systemic lupus erythematosus
dc.creator.fl_str_mv Navarro Quiroz, Elkin
Chavez-Estrada, Valeria
Macias-Ochoa, Karime
Ayala-Navarro, María Fernanda
Flores-Aguilar, Aniyensy Sarai
Morales Navarrete, Francisco
de la Cruz Lopez, Fernando
GOMEZ ESCORCIA, LORENA
Musso, Carlos
Aroca Martínez, Gustavo
Gonzales Torres, Henry
Díaz Pérez, Anderson
Cadena Bonfanti, Andres Angélo
Sarmiento Gutiérrez, Joany
Meza, Jainy
Diaz Arroyo, Esperanza
Bello-Lemus, Yesit
Ahmad, Mostapha
Navarro Quiroz, Roberto
dc.contributor.author.spa.fl_str_mv Navarro Quiroz, Elkin
Chavez-Estrada, Valeria
Macias-Ochoa, Karime
Ayala-Navarro, María Fernanda
Flores-Aguilar, Aniyensy Sarai
Morales Navarrete, Francisco
de la Cruz Lopez, Fernando
GOMEZ ESCORCIA, LORENA
Musso, Carlos
Aroca Martínez, Gustavo
Gonzales Torres, Henry
Díaz Pérez, Anderson
Cadena Bonfanti, Andres Angélo
Sarmiento Gutiérrez, Joany
Meza, Jainy
Diaz Arroyo, Esperanza
Bello-Lemus, Yesit
Ahmad, Mostapha
Navarro Quiroz, Roberto
dc.subject.spa.fl_str_mv Posttranslational modifications
Epigenetic mechanisms
Systemic lupus erythematosus
Ubiquitination
SUMOylation
Glycosylation
Hydroxylation
Phosphorylation
Sulfation
Acetylation
topic Posttranslational modifications
Epigenetic mechanisms
Systemic lupus erythematosus
Ubiquitination
SUMOylation
Glycosylation
Hydroxylation
Phosphorylation
Sulfation
Acetylation
description The complex physiology of eukaryotic cells is regulated through numerous mechanisms, including epigenetic changes and posttranslational modifications. The wide-ranging diversity of these mechanisms constitutes a way of dynamic regulation of the functionality of proteins, their activity, and their subcellular localization as well as modulation of the di erential expression of genes in response to external and internal stimuli that allow an organism to respond or adapt to accordingly. However, alterations in these mechanisms have been evidenced in several autoimmune diseases, including systemic lupus erythematosus (SLE). The present review aims to provide an approach to the current knowledge of the implications of these mechanisms in SLE pathophysiology.
publishDate 2019
dc.date.issued.none.fl_str_mv 2019-11-13
dc.date.accessioned.none.fl_str_mv 2020-03-06T19:37:56Z
dc.date.available.none.fl_str_mv 2020-03-06T19:37:56Z
dc.type.spa.fl_str_mv Artículo de revista
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_2df8fbb1
dc.type.coar.spa.fl_str_mv http://purl.org/coar/resource_type/c_6501
dc.type.content.spa.fl_str_mv Text
dc.type.driver.spa.fl_str_mv info:eu-repo/semantics/article
dc.type.redcol.spa.fl_str_mv http://purl.org/redcol/resource_type/ART
dc.type.version.spa.fl_str_mv info:eu-repo/semantics/acceptedVersion
format http://purl.org/coar/resource_type/c_6501
status_str acceptedVersion
dc.identifier.issn.spa.fl_str_mv 1422-0067
dc.identifier.uri.spa.fl_str_mv https://hdl.handle.net/11323/6084
dc.identifier.doi.spa.fl_str_mv doi:10.3390/ijms20225679
dc.identifier.instname.spa.fl_str_mv Corporación Universidad de la Costa
dc.identifier.reponame.spa.fl_str_mv REDICUC - Repositorio CUC
dc.identifier.repourl.spa.fl_str_mv https://repositorio.cuc.edu.co/
identifier_str_mv 1422-0067
doi:10.3390/ijms20225679
Corporación Universidad de la Costa
REDICUC - Repositorio CUC
url https://hdl.handle.net/11323/6084
https://repositorio.cuc.edu.co/
dc.language.iso.none.fl_str_mv eng
language eng
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spelling Navarro Quiroz, ElkinChavez-Estrada, ValeriaMacias-Ochoa, KarimeAyala-Navarro, María FernandaFlores-Aguilar, Aniyensy SaraiMorales Navarrete, Franciscode la Cruz Lopez, FernandoGOMEZ ESCORCIA, LORENAMusso, CarlosAroca Martínez, GustavoGonzales Torres, HenryDíaz Pérez, AndersonCadena Bonfanti, Andres AngéloSarmiento Gutiérrez, JoanyMeza, JainyDiaz Arroyo, EsperanzaBello-Lemus, YesitAhmad, MostaphaNavarro Quiroz, Roberto2020-03-06T19:37:56Z2020-03-06T19:37:56Z2019-11-131422-0067https://hdl.handle.net/11323/6084doi:10.3390/ijms20225679Corporación Universidad de la CostaREDICUC - Repositorio CUChttps://repositorio.cuc.edu.co/The complex physiology of eukaryotic cells is regulated through numerous mechanisms, including epigenetic changes and posttranslational modifications. The wide-ranging diversity of these mechanisms constitutes a way of dynamic regulation of the functionality of proteins, their activity, and their subcellular localization as well as modulation of the di erential expression of genes in response to external and internal stimuli that allow an organism to respond or adapt to accordingly. However, alterations in these mechanisms have been evidenced in several autoimmune diseases, including systemic lupus erythematosus (SLE). The present review aims to provide an approach to the current knowledge of the implications of these mechanisms in SLE pathophysiology.Navarro Quiroz, Elkin-will be generated-orcid-0000-0001-7567-6409-600Chavez-Estrada, ValeriaMacias-Ochoa, KarimeAyala-Navarro, María FernandaFlores-Aguilar, Aniyensy SaraiMorales Navarrete, Francisco-will be generated-orcid-0000-0002-3461-7186-600de la Cruz Lopez, FernandoGOMEZ ESCORCIA, LORENA-will be generated-orcid-0000-0002-9736-6417-600Musso, Carlos-will be generated-orcid-0000-0003-4928-1280-600Aroca Martínez, GustavoGonzales Torres, HenryDíaz Pérez, AndersonCadena Bonfanti, Andres Angélo-will be generated-orcid-0000-0003-3903-1915-600Sarmiento Gutiérrez, JoanyMeza, JainyDiaz Arroyo, Esperanza-will be generated-orcid-0000-0002-3286-022X-600Bello-Lemus, Yesit-will be generated-orcid-0000-0003-1006-0042-600Ahmad, Mostapha-will be generated-orcid-0000-0002-3825-9478-600Navarro Quiroz, RobertoengInternational Journal of Molecular SciencesCC0 1.0 Universalhttp://creativecommons.org/publicdomain/zero/1.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Posttranslational modificationsEpigenetic mechanismsSystemic lupus erythematosusUbiquitinationSUMOylationGlycosylationHydroxylationPhosphorylationSulfationAcetylationEpigenetic mechanisms and posttranslational Modifications in systemic lupus erythematosusArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/acceptedVersion1. 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