Using discrete-event-simulation for improving operational efficiency in laboratories: a case study in pharmaceutical industry
Just-in-time delivery has become a key aspect of pharmaceutical industry when loyalizing customers and competing internationally. Additionally, prolonged lead times may lead to increased work-in-process inventory, penalties for non-compliance and cost overrun. The problem is more complex upon consid...
- Autores:
-
Troncoso Palacio, Alexander
Neira Rodado, Dionicio
Ortiz Barrios, Miguel Angel
Jimenez, Genett
Hernandez Palma, Hugo Gaspar
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2018
- Institución:
- Corporación Universidad de la Costa
- Repositorio:
- REDICUC - Repositorio CUC
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.cuc.edu.co:11323/1545
- Acceso en línea:
- https://hdl.handle.net/11323/1545
https://repositorio.cuc.edu.co/
- Palabra clave:
- Discrete-event simulation (DES)
Pharmaceutical industry
Productivity rate
Proportion of tardy jobs
- Rights
- openAccess
- License
- Atribución – No comercial – Compartir igual
id |
RCUC2_f43b78d05cd6d35feda9efb2c9348683 |
---|---|
oai_identifier_str |
oai:repositorio.cuc.edu.co:11323/1545 |
network_acronym_str |
RCUC2 |
network_name_str |
REDICUC - Repositorio CUC |
repository_id_str |
|
dc.title.eng.fl_str_mv |
Using discrete-event-simulation for improving operational efficiency in laboratories: a case study in pharmaceutical industry |
title |
Using discrete-event-simulation for improving operational efficiency in laboratories: a case study in pharmaceutical industry |
spellingShingle |
Using discrete-event-simulation for improving operational efficiency in laboratories: a case study in pharmaceutical industry Discrete-event simulation (DES) Pharmaceutical industry Productivity rate Proportion of tardy jobs |
title_short |
Using discrete-event-simulation for improving operational efficiency in laboratories: a case study in pharmaceutical industry |
title_full |
Using discrete-event-simulation for improving operational efficiency in laboratories: a case study in pharmaceutical industry |
title_fullStr |
Using discrete-event-simulation for improving operational efficiency in laboratories: a case study in pharmaceutical industry |
title_full_unstemmed |
Using discrete-event-simulation for improving operational efficiency in laboratories: a case study in pharmaceutical industry |
title_sort |
Using discrete-event-simulation for improving operational efficiency in laboratories: a case study in pharmaceutical industry |
dc.creator.fl_str_mv |
Troncoso Palacio, Alexander Neira Rodado, Dionicio Ortiz Barrios, Miguel Angel Jimenez, Genett Hernandez Palma, Hugo Gaspar |
dc.contributor.author.spa.fl_str_mv |
Troncoso Palacio, Alexander Neira Rodado, Dionicio Ortiz Barrios, Miguel Angel Jimenez, Genett Hernandez Palma, Hugo Gaspar |
dc.subject.eng.fl_str_mv |
Discrete-event simulation (DES) Pharmaceutical industry Productivity rate Proportion of tardy jobs |
topic |
Discrete-event simulation (DES) Pharmaceutical industry Productivity rate Proportion of tardy jobs |
description |
Just-in-time delivery has become a key aspect of pharmaceutical industry when loyalizing customers and competing internationally. Additionally, prolonged lead times may lead to increased work-in-process inventory, penalties for non-compliance and cost overrun. The problem is more complex upon considering a wide variety of products as often noted in pharmaceutical companies. It is then relevant to design strategies focusing on improving the delivery performance. Therefore, this paper proposes the use of Discrete-event simulation (DES) to identify inefficiencies and define solutions for the delivery problem. First, input data were gathered and analyzed. Then, a DES model was developed and validated. Finally, potential improvement scenarios were simulated and analyzed regarding productivity rate and proportion of tardy jobs. A case study in a pharmaceutical laboratory is presented to validate the proposed methodology. The results evidenced that, by implementing the best scenario, the productivity may be augmented by 44.83% which would generate zero tardy jobs. © 2018, Springer International Publishing AG, part of Springer Nature |
publishDate |
2018 |
dc.date.accessioned.none.fl_str_mv |
2018-11-20T22:08:01Z |
dc.date.available.none.fl_str_mv |
2018-11-20T22:08:01Z |
dc.date.issued.none.fl_str_mv |
2018 |
dc.type.spa.fl_str_mv |
Artículo de revista |
dc.type.coar.fl_str_mv |
http://purl.org/coar/resource_type/c_2df8fbb1 |
dc.type.coar.spa.fl_str_mv |
http://purl.org/coar/resource_type/c_6501 |
dc.type.content.spa.fl_str_mv |
Text |
dc.type.driver.spa.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.redcol.spa.fl_str_mv |
http://purl.org/redcol/resource_type/ART |
dc.type.version.spa.fl_str_mv |
info:eu-repo/semantics/acceptedVersion |
format |
http://purl.org/coar/resource_type/c_6501 |
status_str |
acceptedVersion |
dc.identifier.issn.spa.fl_str_mv |
0302-9743 |
dc.identifier.uri.spa.fl_str_mv |
https://hdl.handle.net/11323/1545 |
dc.identifier.instname.spa.fl_str_mv |
Corporación Universidad de la Costa |
dc.identifier.reponame.spa.fl_str_mv |
REDICUC - Repositorio CUC |
dc.identifier.repourl.spa.fl_str_mv |
https://repositorio.cuc.edu.co/ |
identifier_str_mv |
0302-9743 Corporación Universidad de la Costa REDICUC - Repositorio CUC |
url |
https://hdl.handle.net/11323/1545 https://repositorio.cuc.edu.co/ |
dc.language.iso.none.fl_str_mv |
eng |
language |
eng |
dc.rights.spa.fl_str_mv |
Atribución – No comercial – Compartir igual |
dc.rights.accessrights.spa.fl_str_mv |
info:eu-repo/semantics/openAccess |
dc.rights.coar.spa.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 |
rights_invalid_str_mv |
Atribución – No comercial – Compartir igual http://purl.org/coar/access_right/c_abf2 |
eu_rights_str_mv |
openAccess |
dc.publisher.spa.fl_str_mv |
Lecture Notes in Computer Science |
institution |
Corporación Universidad de la Costa |
bitstream.url.fl_str_mv |
https://repositorio.cuc.edu.co/bitstreams/5c12ea11-618a-4322-95eb-e54e75c28bcb/download https://repositorio.cuc.edu.co/bitstreams/9669771c-380c-4783-87be-2a658456573f/download https://repositorio.cuc.edu.co/bitstreams/c1f5f738-2394-4aa2-a9fd-4e977f838e6b/download https://repositorio.cuc.edu.co/bitstreams/1d6b4a3b-fb7a-4220-9dfe-e5c0121638d2/download |
bitstream.checksum.fl_str_mv |
9d97698a2652fd4f88cc1e5ede3b62cc 8a4605be74aa9ea9d79846c1fba20a33 e31695b4382c242ba60e75c496c412cd 5381643ff68f76cefd358ea2b760a84e |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 MD5 |
repository.name.fl_str_mv |
Repositorio de la Universidad de la Costa CUC |
repository.mail.fl_str_mv |
repdigital@cuc.edu.co |
_version_ |
1811760847679127552 |
spelling |
Troncoso Palacio, AlexanderNeira Rodado, DionicioOrtiz Barrios, Miguel AngelJimenez, GenettHernandez Palma, Hugo Gaspar2018-11-20T22:08:01Z2018-11-20T22:08:01Z20180302-9743https://hdl.handle.net/11323/1545Corporación Universidad de la CostaREDICUC - Repositorio CUChttps://repositorio.cuc.edu.co/Just-in-time delivery has become a key aspect of pharmaceutical industry when loyalizing customers and competing internationally. Additionally, prolonged lead times may lead to increased work-in-process inventory, penalties for non-compliance and cost overrun. The problem is more complex upon considering a wide variety of products as often noted in pharmaceutical companies. It is then relevant to design strategies focusing on improving the delivery performance. Therefore, this paper proposes the use of Discrete-event simulation (DES) to identify inefficiencies and define solutions for the delivery problem. First, input data were gathered and analyzed. Then, a DES model was developed and validated. Finally, potential improvement scenarios were simulated and analyzed regarding productivity rate and proportion of tardy jobs. A case study in a pharmaceutical laboratory is presented to validate the proposed methodology. The results evidenced that, by implementing the best scenario, the productivity may be augmented by 44.83% which would generate zero tardy jobs. © 2018, Springer International Publishing AG, part of Springer NatureTroncoso Palacio, Alexander Humberto-0000-0001-6034-695X-600Neira Rodado, Dionicio-0000-0003-0837-7083-600Ortiz Barrios, Miguel Angel-0000-0001-6890-7547-600Jimenez, Genett-c617c38d-cd1c-4e6d-86d7-f49de63ce897-0Hernandez Palma, Hugo Gaspar-e61b91ea-3fac-4266-9fbc-a1c4e4286f47-0engLecture Notes in Computer ScienceAtribución – No comercial – Compartir igualinfo:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Discrete-event simulation (DES)Pharmaceutical industryProductivity rateProportion of tardy jobsUsing discrete-event-simulation for improving operational efficiency in laboratories: a case study in pharmaceutical industryArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/acceptedVersionPublicationORIGINALUsing discrete-event-simulation for improving operational efficiency in laboratories a case study in pharmaceutical industry.pdfUsing discrete-event-simulation for improving operational efficiency in laboratories a case study in pharmaceutical industry.pdfapplication/pdf179845https://repositorio.cuc.edu.co/bitstreams/5c12ea11-618a-4322-95eb-e54e75c28bcb/download9d97698a2652fd4f88cc1e5ede3b62ccMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://repositorio.cuc.edu.co/bitstreams/9669771c-380c-4783-87be-2a658456573f/download8a4605be74aa9ea9d79846c1fba20a33MD52THUMBNAILUsing discrete-event-simulation for improving operational efficiency in laboratories a case study in pharmaceutical industry.pdf.jpgUsing discrete-event-simulation for improving operational efficiency in laboratories a case study in pharmaceutical industry.pdf.jpgimage/jpeg41881https://repositorio.cuc.edu.co/bitstreams/c1f5f738-2394-4aa2-a9fd-4e977f838e6b/downloade31695b4382c242ba60e75c496c412cdMD54TEXTUsing discrete-event-simulation for improving operational efficiency in laboratories a case study in pharmaceutical industry.pdf.txtUsing discrete-event-simulation for improving operational efficiency in laboratories a case study in pharmaceutical industry.pdf.txttext/plain1521https://repositorio.cuc.edu.co/bitstreams/1d6b4a3b-fb7a-4220-9dfe-e5c0121638d2/download5381643ff68f76cefd358ea2b760a84eMD5511323/1545oai:repositorio.cuc.edu.co:11323/15452024-09-17 14:10:16.656open.accesshttps://repositorio.cuc.edu.coRepositorio de la Universidad de la Costa CUCrepdigital@cuc.edu.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 |