Using discrete-event-simulation for improving operational efficiency in laboratories: a case study in pharmaceutical industry

Just-in-time delivery has become a key aspect of pharmaceutical industry when loyalizing customers and competing internationally. Additionally, prolonged lead times may lead to increased work-in-process inventory, penalties for non-compliance and cost overrun. The problem is more complex upon consid...

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Autores:
Troncoso Palacio, Alexander
Neira Rodado, Dionicio
Ortiz Barrios, Miguel Angel
Jimenez, Genett
Hernandez Palma, Hugo Gaspar
Tipo de recurso:
Article of journal
Fecha de publicación:
2018
Institución:
Corporación Universidad de la Costa
Repositorio:
REDICUC - Repositorio CUC
Idioma:
eng
OAI Identifier:
oai:repositorio.cuc.edu.co:11323/1545
Acceso en línea:
https://hdl.handle.net/11323/1545
https://repositorio.cuc.edu.co/
Palabra clave:
Discrete-event simulation (DES)
Pharmaceutical industry
Productivity rate
Proportion of tardy jobs
Rights
openAccess
License
Atribución – No comercial – Compartir igual
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dc.title.eng.fl_str_mv Using discrete-event-simulation for improving operational efficiency in laboratories: a case study in pharmaceutical industry
title Using discrete-event-simulation for improving operational efficiency in laboratories: a case study in pharmaceutical industry
spellingShingle Using discrete-event-simulation for improving operational efficiency in laboratories: a case study in pharmaceutical industry
Discrete-event simulation (DES)
Pharmaceutical industry
Productivity rate
Proportion of tardy jobs
title_short Using discrete-event-simulation for improving operational efficiency in laboratories: a case study in pharmaceutical industry
title_full Using discrete-event-simulation for improving operational efficiency in laboratories: a case study in pharmaceutical industry
title_fullStr Using discrete-event-simulation for improving operational efficiency in laboratories: a case study in pharmaceutical industry
title_full_unstemmed Using discrete-event-simulation for improving operational efficiency in laboratories: a case study in pharmaceutical industry
title_sort Using discrete-event-simulation for improving operational efficiency in laboratories: a case study in pharmaceutical industry
dc.creator.fl_str_mv Troncoso Palacio, Alexander
Neira Rodado, Dionicio
Ortiz Barrios, Miguel Angel
Jimenez, Genett
Hernandez Palma, Hugo Gaspar
dc.contributor.author.spa.fl_str_mv Troncoso Palacio, Alexander
Neira Rodado, Dionicio
Ortiz Barrios, Miguel Angel
Jimenez, Genett
Hernandez Palma, Hugo Gaspar
dc.subject.eng.fl_str_mv Discrete-event simulation (DES)
Pharmaceutical industry
Productivity rate
Proportion of tardy jobs
topic Discrete-event simulation (DES)
Pharmaceutical industry
Productivity rate
Proportion of tardy jobs
description Just-in-time delivery has become a key aspect of pharmaceutical industry when loyalizing customers and competing internationally. Additionally, prolonged lead times may lead to increased work-in-process inventory, penalties for non-compliance and cost overrun. The problem is more complex upon considering a wide variety of products as often noted in pharmaceutical companies. It is then relevant to design strategies focusing on improving the delivery performance. Therefore, this paper proposes the use of Discrete-event simulation (DES) to identify inefficiencies and define solutions for the delivery problem. First, input data were gathered and analyzed. Then, a DES model was developed and validated. Finally, potential improvement scenarios were simulated and analyzed regarding productivity rate and proportion of tardy jobs. A case study in a pharmaceutical laboratory is presented to validate the proposed methodology. The results evidenced that, by implementing the best scenario, the productivity may be augmented by 44.83% which would generate zero tardy jobs. © 2018, Springer International Publishing AG, part of Springer Nature
publishDate 2018
dc.date.accessioned.none.fl_str_mv 2018-11-20T22:08:01Z
dc.date.available.none.fl_str_mv 2018-11-20T22:08:01Z
dc.date.issued.none.fl_str_mv 2018
dc.type.spa.fl_str_mv Artículo de revista
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dc.identifier.issn.spa.fl_str_mv 0302-9743
dc.identifier.uri.spa.fl_str_mv https://hdl.handle.net/11323/1545
dc.identifier.instname.spa.fl_str_mv Corporación Universidad de la Costa
dc.identifier.reponame.spa.fl_str_mv REDICUC - Repositorio CUC
dc.identifier.repourl.spa.fl_str_mv https://repositorio.cuc.edu.co/
identifier_str_mv 0302-9743
Corporación Universidad de la Costa
REDICUC - Repositorio CUC
url https://hdl.handle.net/11323/1545
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dc.language.iso.none.fl_str_mv eng
language eng
dc.rights.spa.fl_str_mv Atribución – No comercial – Compartir igual
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rights_invalid_str_mv Atribución – No comercial – Compartir igual
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.publisher.spa.fl_str_mv Lecture Notes in Computer Science
institution Corporación Universidad de la Costa
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spelling Troncoso Palacio, AlexanderNeira Rodado, DionicioOrtiz Barrios, Miguel AngelJimenez, GenettHernandez Palma, Hugo Gaspar2018-11-20T22:08:01Z2018-11-20T22:08:01Z20180302-9743https://hdl.handle.net/11323/1545Corporación Universidad de la CostaREDICUC - Repositorio CUChttps://repositorio.cuc.edu.co/Just-in-time delivery has become a key aspect of pharmaceutical industry when loyalizing customers and competing internationally. Additionally, prolonged lead times may lead to increased work-in-process inventory, penalties for non-compliance and cost overrun. The problem is more complex upon considering a wide variety of products as often noted in pharmaceutical companies. It is then relevant to design strategies focusing on improving the delivery performance. Therefore, this paper proposes the use of Discrete-event simulation (DES) to identify inefficiencies and define solutions for the delivery problem. First, input data were gathered and analyzed. Then, a DES model was developed and validated. Finally, potential improvement scenarios were simulated and analyzed regarding productivity rate and proportion of tardy jobs. A case study in a pharmaceutical laboratory is presented to validate the proposed methodology. The results evidenced that, by implementing the best scenario, the productivity may be augmented by 44.83% which would generate zero tardy jobs. © 2018, Springer International Publishing AG, part of Springer NatureTroncoso Palacio, Alexander Humberto-0000-0001-6034-695X-600Neira Rodado, Dionicio-0000-0003-0837-7083-600Ortiz Barrios, Miguel Angel-0000-0001-6890-7547-600Jimenez, Genett-c617c38d-cd1c-4e6d-86d7-f49de63ce897-0Hernandez Palma, Hugo Gaspar-e61b91ea-3fac-4266-9fbc-a1c4e4286f47-0engLecture Notes in Computer ScienceAtribución – No comercial – Compartir igualinfo:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Discrete-event simulation (DES)Pharmaceutical industryProductivity rateProportion of tardy jobsUsing discrete-event-simulation for improving operational efficiency in laboratories: a case study in pharmaceutical industryArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/acceptedVersionPublicationORIGINALUsing discrete-event-simulation for improving operational efficiency in laboratories a case study in pharmaceutical industry.pdfUsing discrete-event-simulation for improving operational efficiency in laboratories a case study in pharmaceutical industry.pdfapplication/pdf179845https://repositorio.cuc.edu.co/bitstreams/5c12ea11-618a-4322-95eb-e54e75c28bcb/download9d97698a2652fd4f88cc1e5ede3b62ccMD51LICENSElicense.txtlicense.txttext/plain; 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