Acute thalamic ischemic stroke in an older patient newly vaccinated with COVID-19 vaccine based on adenoviral vectors

Introduction. Recent reports have shown several cases of cerebrovascular events after vaccination against COVID-19. The e ects have been described mainly in women within the ¬ rst two weeks of receiving the vaccine. Clinical Case. We describe here the ¬ rst Colombian case of a cerebrovascular event...

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Autores:: Mesa-Gamarra, Kelly
PINEDA PATERNINA, MARIO
Castillo, Edgar
Camargo, Loida
Pabón, Alexander
Herrera-Pino, Jorge Alfredo
Caldichoury, Nicole
Gargiulo, Pascual A.
Flórez, Yuliana
López, Norman

Tipo de recurso:: Article of investigation

Fecha de publicación:: 2022

Institución:: Corporación Universidad de la Costa

Repositorio:: REDICUC - Repositorio CUC

Idioma:: eng

Description
Summary:	Introduction. Recent reports have shown several cases of cerebrovascular events after vaccination against COVID-19. The e ects have been described mainly in women within the ¬ rst two weeks of receiving the vaccine. Clinical Case. We describe here the ¬ rst Colombian case of a cerebrovascular event after vaccination against COVID-19 in a 67-year-old woman with a vascular history. Four days after application of the messenger ribonucleic acid (mRNA) vaccine, she exhibited deviation of the labial commissure, ipsilateral ptosis, and limitation of march with lateralization. The event was associated with a subacute ischemic event in the right thalamus in parasagittal situation, changes in chronic ischemic microangiopathy of small vessels, and vascular crossing in the right cerebellar angle, without other alternative causes. Conclusion. The development and rapid use of vaccines has allowed the hospitalization and mortality statistics associated with COVID-19 to be reduced, but at the same time, it has generated concern about the potential side e ects, generating controversy among the general population, especially in individuals with cardiovascular diseases. In our case, we provided evidence for the discussion of potential cerebrovascular events related to the application of vaccines in older people with a history of cerebrovascular diseases. This was done in order to analyze and control in subsequent studies the modulation of medical history on the likely e ects of vaccination. However, despite the unavoidable side e ects, the bene¬ ts of vaccination are superior.

Acute thalamic ischemic stroke in an older patient newly vaccinated with COVID-19 vaccine based on adenoviral vectors

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