Budgetary impact analysis of preexposure prophylaxis (prep) strategy for the prevention of hiv in Colombia, 2019-2021

We aimed to estimate the budgetary impact of a PrEP strategy for the prevention and control of HIV in men who have sex with men (MSM) and transgender women (TGW) in Colombia. We adapted a budgetary impact model developed by Fundación Oswaldo Fiocruz, Brazil. Modelling was performed from the third-pa...

Full description

Autores:
ALVIS-ZAKZUK, NELSON J.
Tolosa Perez, N
Buitrago, Giancarlo
Alvarez Moreno, Carlos
CARRASQUILLA SOTOMAYOR, MARIA
De La Hoz, Fernando Pio
Tipo de recurso:
http://purl.org/coar/resource_type/c_816b
Fecha de publicación:
2020
Institución:
Corporación Universidad de la Costa
Repositorio:
REDICUC - Repositorio CUC
Idioma:
eng
OAI Identifier:
oai:repositorio.cuc.edu.co:11323/8338
Acceso en línea:
https://hdl.handle.net/11323/8338
https://doi.org/10.1016/j.jval.2020.04.508
https://repositorio.cuc.edu.co/
Palabra clave:
VIH
Colombia
Prevention
Control
Rights
openAccess
License
CC0 1.0 Universal
id RCUC2_d1c5ed1a1e7ed06b8e31181c42e57676
oai_identifier_str oai:repositorio.cuc.edu.co:11323/8338
network_acronym_str RCUC2
network_name_str REDICUC - Repositorio CUC
repository_id_str
dc.title.eng.fl_str_mv Budgetary impact analysis of preexposure prophylaxis (prep) strategy for the prevention of hiv in Colombia, 2019-2021
title Budgetary impact analysis of preexposure prophylaxis (prep) strategy for the prevention of hiv in Colombia, 2019-2021
spellingShingle Budgetary impact analysis of preexposure prophylaxis (prep) strategy for the prevention of hiv in Colombia, 2019-2021
VIH
Colombia
Prevention
Control
title_short Budgetary impact analysis of preexposure prophylaxis (prep) strategy for the prevention of hiv in Colombia, 2019-2021
title_full Budgetary impact analysis of preexposure prophylaxis (prep) strategy for the prevention of hiv in Colombia, 2019-2021
title_fullStr Budgetary impact analysis of preexposure prophylaxis (prep) strategy for the prevention of hiv in Colombia, 2019-2021
title_full_unstemmed Budgetary impact analysis of preexposure prophylaxis (prep) strategy for the prevention of hiv in Colombia, 2019-2021
title_sort Budgetary impact analysis of preexposure prophylaxis (prep) strategy for the prevention of hiv in Colombia, 2019-2021
dc.creator.fl_str_mv ALVIS-ZAKZUK, NELSON J.
Tolosa Perez, N
Buitrago, Giancarlo
Alvarez Moreno, Carlos
CARRASQUILLA SOTOMAYOR, MARIA
De La Hoz, Fernando Pio
dc.contributor.author.spa.fl_str_mv ALVIS-ZAKZUK, NELSON J.
Tolosa Perez, N
Buitrago, Giancarlo
Alvarez Moreno, Carlos
CARRASQUILLA SOTOMAYOR, MARIA
De La Hoz, Fernando Pio
dc.subject.eng.fl_str_mv VIH
Colombia
Prevention
Control
topic VIH
Colombia
Prevention
Control
description We aimed to estimate the budgetary impact of a PrEP strategy for the prevention and control of HIV in men who have sex with men (MSM) and transgender women (TGW) in Colombia. We adapted a budgetary impact model developed by Fundación Oswaldo Fiocruz, Brazil. Modelling was performed from the third-payer perspective over a 3-year period. Epidemiological and cost inputs were extracted from literature reviews and Colombian data. Two scenarios were simulated: 1. No PrEP scenario; and, 2. New scenario: MSM and TGW would have access to a PrEP program, which potentially reduce the HIV cases. Costs include the sum of PrEP program costs for MSM and TGW, and the treatment costs of cases that will occur in the 3-years of implementation. The new scenario was modelled at different risk and PrEP program coverage levels. Budget impact analysis (BIA) was calculated as the difference between the two scenarios. Cost were reported in Colombian pesos (COP). At a PrEP coverage of 80% and an incidence of 4.5 per 100 person-year would be avoid 4,057, 4,315 and 4,383 HIV cases in MSM for years 1, 2 and 3, respectively. The BIA was COP$47 billion for year 1; COP$20 billion for the second, and for the third year the PrEP program would save COP$11 billion. In TGW, at a PrEP coverage of 80% and an incidence of 7.3 per 100 person-year would be avoid 757, 805 and 817 HIV cases for the three years. The BIA was COP$3.3 billion, COP$-2.1 billion and COP$-8.1 billion, respectively. PrEP strategy should focus on small fractions of the population at high risk, such as those addressed in our study. Our results suggest that PrEP program would avoid cases and save costs for the Colombian health system.
publishDate 2020
dc.date.issued.none.fl_str_mv 2020
dc.date.accessioned.none.fl_str_mv 2021-06-02T19:10:40Z
dc.date.available.none.fl_str_mv 2021-06-02T19:10:40Z
dc.date.embargoEnd.none.fl_str_mv 2022
dc.type.spa.fl_str_mv Pre-Publicación
dc.type.coar.spa.fl_str_mv http://purl.org/coar/resource_type/c_816b
dc.type.content.spa.fl_str_mv Text
dc.type.driver.spa.fl_str_mv info:eu-repo/semantics/preprint
dc.type.redcol.spa.fl_str_mv http://purl.org/redcol/resource_type/ARTOTR
dc.type.version.spa.fl_str_mv info:eu-repo/semantics/acceptedVersion
format http://purl.org/coar/resource_type/c_816b
status_str acceptedVersion
dc.identifier.issn.spa.fl_str_mv 1098-3015
dc.identifier.uri.spa.fl_str_mv https://hdl.handle.net/11323/8338
dc.identifier.doi.spa.fl_str_mv https://doi.org/10.1016/j.jval.2020.04.508
dc.identifier.instname.spa.fl_str_mv Corporación Universidad de la Costa
dc.identifier.reponame.spa.fl_str_mv REDICUC - Repositorio CUC
dc.identifier.repourl.spa.fl_str_mv https://repositorio.cuc.edu.co/
identifier_str_mv 1098-3015
Corporación Universidad de la Costa
REDICUC - Repositorio CUC
url https://hdl.handle.net/11323/8338
https://doi.org/10.1016/j.jval.2020.04.508
https://repositorio.cuc.edu.co/
dc.language.iso.none.fl_str_mv eng
language eng
dc.rights.spa.fl_str_mv CC0 1.0 Universal
dc.rights.uri.spa.fl_str_mv http://creativecommons.org/publicdomain/zero/1.0/
dc.rights.accessrights.spa.fl_str_mv info:eu-repo/semantics/openAccess
dc.rights.coar.spa.fl_str_mv http://purl.org/coar/access_right/c_abf2
rights_invalid_str_mv CC0 1.0 Universal
http://creativecommons.org/publicdomain/zero/1.0/
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.mimetype.spa.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Corporación Universidad de la Costa
dc.source.spa.fl_str_mv Value in Health
institution Corporación Universidad de la Costa
dc.source.url.spa.fl_str_mv https://www.valueinhealthjournal.com/article/S1098-3015(20)30696-3/fulltext
bitstream.url.fl_str_mv https://repositorio.cuc.edu.co/bitstream/11323/8338/2/license_rdf
https://repositorio.cuc.edu.co/bitstream/11323/8338/3/license.txt
https://repositorio.cuc.edu.co/bitstream/11323/8338/4/Budgetary%20impact%20analysis%20of%20preexposure%20prophylaxis%20%28prep%29%20strategy%20for%20the%20prevention%20of%20hiv%20in%20Colombia%2c%202019-2021.pdf
https://repositorio.cuc.edu.co/bitstream/11323/8338/5/Budgetary%20impact%20analysis%20of%20preexposure%20prophylaxis%20%28prep%29%20strategy%20for%20the%20prevention%20of%20hiv%20in%20Colombia%2c%202019-2021.pdf.jpg
https://repositorio.cuc.edu.co/bitstream/11323/8338/6/Budgetary%20impact%20analysis%20of%20preexposure%20prophylaxis%20%28prep%29%20strategy%20for%20the%20prevention%20of%20hiv%20in%20Colombia%2c%202019-2021.pdf.txt
bitstream.checksum.fl_str_mv 42fd4ad1e89814f5e4a476b409eb708c
e30e9215131d99561d40d6b0abbe9bad
f43b5299bf59e3663997143b3ad5cddb
6496418bb9acf8f866784c7bcf52ee19
bf7c276a013ad50174dbf0dea2d8bb79
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
MD5
MD5
repository.name.fl_str_mv Repositorio Universidad de La Costa
repository.mail.fl_str_mv bdigital@metabiblioteca.com
_version_ 1808400010774052864
spelling ALVIS-ZAKZUK, NELSON J.382e6397ae2b49cf5c0177ca2eded476Tolosa Perez, N5c0d85e3061d9270517308f5e2e0f1fdBuitrago, Giancarlo19a82f19b8c97c639a7055263d101c08Alvarez Moreno, Carlos870cdb671ade986a27081e74a4264a6fCARRASQUILLA SOTOMAYOR, MARIA67c9faeb542982223e54ba3908baaed7De La Hoz, Fernando Pio2d597537696afbc04ec279b54c3701562021-06-02T19:10:40Z2021-06-02T19:10:40Z202020221098-3015https://hdl.handle.net/11323/8338https://doi.org/10.1016/j.jval.2020.04.508Corporación Universidad de la CostaREDICUC - Repositorio CUChttps://repositorio.cuc.edu.co/We aimed to estimate the budgetary impact of a PrEP strategy for the prevention and control of HIV in men who have sex with men (MSM) and transgender women (TGW) in Colombia. We adapted a budgetary impact model developed by Fundación Oswaldo Fiocruz, Brazil. Modelling was performed from the third-payer perspective over a 3-year period. Epidemiological and cost inputs were extracted from literature reviews and Colombian data. Two scenarios were simulated: 1. No PrEP scenario; and, 2. New scenario: MSM and TGW would have access to a PrEP program, which potentially reduce the HIV cases. Costs include the sum of PrEP program costs for MSM and TGW, and the treatment costs of cases that will occur in the 3-years of implementation. The new scenario was modelled at different risk and PrEP program coverage levels. Budget impact analysis (BIA) was calculated as the difference between the two scenarios. Cost were reported in Colombian pesos (COP). At a PrEP coverage of 80% and an incidence of 4.5 per 100 person-year would be avoid 4,057, 4,315 and 4,383 HIV cases in MSM for years 1, 2 and 3, respectively. The BIA was COP$47 billion for year 1; COP$20 billion for the second, and for the third year the PrEP program would save COP$11 billion. In TGW, at a PrEP coverage of 80% and an incidence of 7.3 per 100 person-year would be avoid 757, 805 and 817 HIV cases for the three years. The BIA was COP$3.3 billion, COP$-2.1 billion and COP$-8.1 billion, respectively. PrEP strategy should focus on small fractions of the population at high risk, such as those addressed in our study. Our results suggest that PrEP program would avoid cases and save costs for the Colombian health system.application/pdfengCorporación Universidad de la CostaCC0 1.0 Universalhttp://creativecommons.org/publicdomain/zero/1.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Value in Healthhttps://www.valueinhealthjournal.com/article/S1098-3015(20)30696-3/fulltextVIHColombiaPreventionControlBudgetary impact analysis of preexposure prophylaxis (prep) strategy for the prevention of hiv in Colombia, 2019-2021Pre-Publicaciónhttp://purl.org/coar/resource_type/c_816bTextinfo:eu-repo/semantics/preprinthttp://purl.org/redcol/resource_type/ARTOTRinfo:eu-repo/semantics/acceptedVersionCC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8701https://repositorio.cuc.edu.co/bitstream/11323/8338/2/license_rdf42fd4ad1e89814f5e4a476b409eb708cMD52open accessLICENSElicense.txtlicense.txttext/plain; charset=utf-83196https://repositorio.cuc.edu.co/bitstream/11323/8338/3/license.txte30e9215131d99561d40d6b0abbe9badMD53open accessORIGINALBudgetary impact analysis of preexposure prophylaxis (prep) strategy for the prevention of hiv in Colombia, 2019-2021.pdfBudgetary impact analysis of preexposure prophylaxis (prep) strategy for the prevention of hiv in Colombia, 2019-2021.pdfapplication/pdf61030https://repositorio.cuc.edu.co/bitstream/11323/8338/4/Budgetary%20impact%20analysis%20of%20preexposure%20prophylaxis%20%28prep%29%20strategy%20for%20the%20prevention%20of%20hiv%20in%20Colombia%2c%202019-2021.pdff43b5299bf59e3663997143b3ad5cddbMD54open accessTHUMBNAILBudgetary impact analysis of preexposure prophylaxis (prep) strategy for the prevention of hiv in Colombia, 2019-2021.pdf.jpgBudgetary impact analysis of preexposure prophylaxis (prep) strategy for the prevention of hiv in Colombia, 2019-2021.pdf.jpgimage/jpeg64306https://repositorio.cuc.edu.co/bitstream/11323/8338/5/Budgetary%20impact%20analysis%20of%20preexposure%20prophylaxis%20%28prep%29%20strategy%20for%20the%20prevention%20of%20hiv%20in%20Colombia%2c%202019-2021.pdf.jpg6496418bb9acf8f866784c7bcf52ee19MD55open accessTEXTBudgetary impact analysis of preexposure prophylaxis (prep) strategy for the prevention of hiv in Colombia, 2019-2021.pdf.txtBudgetary impact analysis of preexposure prophylaxis (prep) strategy for the prevention of hiv in Colombia, 2019-2021.pdf.txttext/plain2006https://repositorio.cuc.edu.co/bitstream/11323/8338/6/Budgetary%20impact%20analysis%20of%20preexposure%20prophylaxis%20%28prep%29%20strategy%20for%20the%20prevention%20of%20hiv%20in%20Colombia%2c%202019-2021.pdf.txtbf7c276a013ad50174dbf0dea2d8bb79MD56open access11323/8338oai:repositorio.cuc.edu.co:11323/83382023-12-14 11:28:17.57CC0 1.0 Universal|||http://creativecommons.org/publicdomain/zero/1.0/open accessRepositorio Universidad de La Costabdigital@metabiblioteca.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