Budgetary impact analysis of preexposure prophylaxis (prep) strategy for the prevention of hiv in Colombia, 2019-2021

We aimed to estimate the budgetary impact of a PrEP strategy for the prevention and control of HIV in men who have sex with men (MSM) and transgender women (TGW) in Colombia. We adapted a budgetary impact model developed by Fundación Oswaldo Fiocruz, Brazil. Modelling was performed from the third-pa...

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Autores:
ALVIS-ZAKZUK, NELSON J.
Tolosa Perez, N
Buitrago, Giancarlo
Alvarez Moreno, Carlos
CARRASQUILLA SOTOMAYOR, MARIA
De La Hoz, Fernando Pio
Tipo de recurso:
http://purl.org/coar/resource_type/c_816b
Fecha de publicación:
2020
Institución:
Corporación Universidad de la Costa
Repositorio:
REDICUC - Repositorio CUC
Idioma:
eng
OAI Identifier:
oai:repositorio.cuc.edu.co:11323/8338
Acceso en línea:
https://hdl.handle.net/11323/8338
https://doi.org/10.1016/j.jval.2020.04.508
https://repositorio.cuc.edu.co/
Palabra clave:
VIH
Colombia
Prevention
Control
Rights
openAccess
License
CC0 1.0 Universal
id RCUC2_d1c5ed1a1e7ed06b8e31181c42e57676
oai_identifier_str oai:repositorio.cuc.edu.co:11323/8338
network_acronym_str RCUC2
network_name_str REDICUC - Repositorio CUC
repository_id_str
dc.title.eng.fl_str_mv Budgetary impact analysis of preexposure prophylaxis (prep) strategy for the prevention of hiv in Colombia, 2019-2021
title Budgetary impact analysis of preexposure prophylaxis (prep) strategy for the prevention of hiv in Colombia, 2019-2021
spellingShingle Budgetary impact analysis of preexposure prophylaxis (prep) strategy for the prevention of hiv in Colombia, 2019-2021
VIH
Colombia
Prevention
Control
title_short Budgetary impact analysis of preexposure prophylaxis (prep) strategy for the prevention of hiv in Colombia, 2019-2021
title_full Budgetary impact analysis of preexposure prophylaxis (prep) strategy for the prevention of hiv in Colombia, 2019-2021
title_fullStr Budgetary impact analysis of preexposure prophylaxis (prep) strategy for the prevention of hiv in Colombia, 2019-2021
title_full_unstemmed Budgetary impact analysis of preexposure prophylaxis (prep) strategy for the prevention of hiv in Colombia, 2019-2021
title_sort Budgetary impact analysis of preexposure prophylaxis (prep) strategy for the prevention of hiv in Colombia, 2019-2021
dc.creator.fl_str_mv ALVIS-ZAKZUK, NELSON J.
Tolosa Perez, N
Buitrago, Giancarlo
Alvarez Moreno, Carlos
CARRASQUILLA SOTOMAYOR, MARIA
De La Hoz, Fernando Pio
dc.contributor.author.spa.fl_str_mv ALVIS-ZAKZUK, NELSON J.
Tolosa Perez, N
Buitrago, Giancarlo
Alvarez Moreno, Carlos
CARRASQUILLA SOTOMAYOR, MARIA
De La Hoz, Fernando Pio
dc.subject.eng.fl_str_mv VIH
Colombia
Prevention
Control
topic VIH
Colombia
Prevention
Control
description We aimed to estimate the budgetary impact of a PrEP strategy for the prevention and control of HIV in men who have sex with men (MSM) and transgender women (TGW) in Colombia. We adapted a budgetary impact model developed by Fundación Oswaldo Fiocruz, Brazil. Modelling was performed from the third-payer perspective over a 3-year period. Epidemiological and cost inputs were extracted from literature reviews and Colombian data. Two scenarios were simulated: 1. No PrEP scenario; and, 2. New scenario: MSM and TGW would have access to a PrEP program, which potentially reduce the HIV cases. Costs include the sum of PrEP program costs for MSM and TGW, and the treatment costs of cases that will occur in the 3-years of implementation. The new scenario was modelled at different risk and PrEP program coverage levels. Budget impact analysis (BIA) was calculated as the difference between the two scenarios. Cost were reported in Colombian pesos (COP). At a PrEP coverage of 80% and an incidence of 4.5 per 100 person-year would be avoid 4,057, 4,315 and 4,383 HIV cases in MSM for years 1, 2 and 3, respectively. The BIA was COP$47 billion for year 1; COP$20 billion for the second, and for the third year the PrEP program would save COP$11 billion. In TGW, at a PrEP coverage of 80% and an incidence of 7.3 per 100 person-year would be avoid 757, 805 and 817 HIV cases for the three years. The BIA was COP$3.3 billion, COP$-2.1 billion and COP$-8.1 billion, respectively. PrEP strategy should focus on small fractions of the population at high risk, such as those addressed in our study. Our results suggest that PrEP program would avoid cases and save costs for the Colombian health system.
publishDate 2020
dc.date.issued.none.fl_str_mv 2020
dc.date.accessioned.none.fl_str_mv 2021-06-02T19:10:40Z
dc.date.available.none.fl_str_mv 2021-06-02T19:10:40Z
dc.date.embargoEnd.none.fl_str_mv 2022
dc.type.spa.fl_str_mv Pre-Publicación
dc.type.coar.spa.fl_str_mv http://purl.org/coar/resource_type/c_816b
dc.type.content.spa.fl_str_mv Text
dc.type.driver.spa.fl_str_mv info:eu-repo/semantics/preprint
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dc.identifier.issn.spa.fl_str_mv 1098-3015
dc.identifier.uri.spa.fl_str_mv https://hdl.handle.net/11323/8338
dc.identifier.doi.spa.fl_str_mv https://doi.org/10.1016/j.jval.2020.04.508
dc.identifier.instname.spa.fl_str_mv Corporación Universidad de la Costa
dc.identifier.reponame.spa.fl_str_mv REDICUC - Repositorio CUC
dc.identifier.repourl.spa.fl_str_mv https://repositorio.cuc.edu.co/
identifier_str_mv 1098-3015
Corporación Universidad de la Costa
REDICUC - Repositorio CUC
url https://hdl.handle.net/11323/8338
https://doi.org/10.1016/j.jval.2020.04.508
https://repositorio.cuc.edu.co/
dc.language.iso.none.fl_str_mv eng
language eng
dc.rights.spa.fl_str_mv CC0 1.0 Universal
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rights_invalid_str_mv CC0 1.0 Universal
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eu_rights_str_mv openAccess
dc.format.mimetype.spa.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Corporación Universidad de la Costa
dc.source.spa.fl_str_mv Value in Health
institution Corporación Universidad de la Costa
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spelling ALVIS-ZAKZUK, NELSON J.Tolosa Perez, NBuitrago, GiancarloAlvarez Moreno, CarlosCARRASQUILLA SOTOMAYOR, MARIADe La Hoz, Fernando Pio2021-06-02T19:10:40Z2021-06-02T19:10:40Z202020221098-3015https://hdl.handle.net/11323/8338https://doi.org/10.1016/j.jval.2020.04.508Corporación Universidad de la CostaREDICUC - Repositorio CUChttps://repositorio.cuc.edu.co/We aimed to estimate the budgetary impact of a PrEP strategy for the prevention and control of HIV in men who have sex with men (MSM) and transgender women (TGW) in Colombia. We adapted a budgetary impact model developed by Fundación Oswaldo Fiocruz, Brazil. Modelling was performed from the third-payer perspective over a 3-year period. Epidemiological and cost inputs were extracted from literature reviews and Colombian data. Two scenarios were simulated: 1. No PrEP scenario; and, 2. New scenario: MSM and TGW would have access to a PrEP program, which potentially reduce the HIV cases. Costs include the sum of PrEP program costs for MSM and TGW, and the treatment costs of cases that will occur in the 3-years of implementation. The new scenario was modelled at different risk and PrEP program coverage levels. Budget impact analysis (BIA) was calculated as the difference between the two scenarios. Cost were reported in Colombian pesos (COP). At a PrEP coverage of 80% and an incidence of 4.5 per 100 person-year would be avoid 4,057, 4,315 and 4,383 HIV cases in MSM for years 1, 2 and 3, respectively. The BIA was COP$47 billion for year 1; COP$20 billion for the second, and for the third year the PrEP program would save COP$11 billion. In TGW, at a PrEP coverage of 80% and an incidence of 7.3 per 100 person-year would be avoid 757, 805 and 817 HIV cases for the three years. The BIA was COP$3.3 billion, COP$-2.1 billion and COP$-8.1 billion, respectively. PrEP strategy should focus on small fractions of the population at high risk, such as those addressed in our study. 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