Driving and Alzheimer's disease: A neuropsychological screening battery for the elderly

As life expectancy increases, there is a marked increase in the elderly population eager to continue driving. A large proportion of these elderly drive safely, however, patients with mild dementia are high-risk drivers. Objective: to identify the cognitive tests that best predict driving ability in...

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Autores:
Crivelli, Lucía
Julieta Russo, María
Franco Farez, Mauricio
Bonetto, Mariana
Prado, Cecilia
Calandri, Ismael Luis
Campos, Jorge
Cohen, Gabriela
Chrem Mendez, Patricio
Sabe, Liliana Raquel
Tipo de recurso:
Article of journal
Fecha de publicación:
2019
Institución:
Corporación Universidad de la Costa
Repositorio:
REDICUC - Repositorio CUC
Idioma:
eng
OAI Identifier:
oai:repositorio.cuc.edu.co:11323/7465
Acceso en línea:
https://hdl.handle.net/11323/7465
http://dx.doi.org/10.1590/1980-57642018dn13-030008
https://repositorio.cuc.edu.co/
Palabra clave:
automobile driving
cognition
Alzheimer's disease
dementia
Rights
openAccess
License
Attribution-NonCommercial-NoDerivatives 4.0 International
id RCUC2_cec821e2dade09f979c8750e9ccbda04
oai_identifier_str oai:repositorio.cuc.edu.co:11323/7465
network_acronym_str RCUC2
network_name_str REDICUC - Repositorio CUC
repository_id_str
dc.title.spa.fl_str_mv Driving and Alzheimer's disease: A neuropsychological screening battery for the elderly
dc.title.translated.spa.fl_str_mv CONDUÇÃO E DOENÇA DE ALZHEIMER: UMA BATERIA DE TRIAGEM NEUROPSICOLÓGICA PARA IDOSOS
title Driving and Alzheimer's disease: A neuropsychological screening battery for the elderly
spellingShingle Driving and Alzheimer's disease: A neuropsychological screening battery for the elderly
automobile driving
cognition
Alzheimer's disease
dementia
title_short Driving and Alzheimer's disease: A neuropsychological screening battery for the elderly
title_full Driving and Alzheimer's disease: A neuropsychological screening battery for the elderly
title_fullStr Driving and Alzheimer's disease: A neuropsychological screening battery for the elderly
title_full_unstemmed Driving and Alzheimer's disease: A neuropsychological screening battery for the elderly
title_sort Driving and Alzheimer's disease: A neuropsychological screening battery for the elderly
dc.creator.fl_str_mv Crivelli, Lucía
Julieta Russo, María
Franco Farez, Mauricio
Bonetto, Mariana
Prado, Cecilia
Calandri, Ismael Luis
Campos, Jorge
Cohen, Gabriela
Chrem Mendez, Patricio
Sabe, Liliana Raquel
dc.contributor.author.spa.fl_str_mv Crivelli, Lucía
Julieta Russo, María
Franco Farez, Mauricio
Bonetto, Mariana
Prado, Cecilia
Calandri, Ismael Luis
Campos, Jorge
Cohen, Gabriela
Chrem Mendez, Patricio
Sabe, Liliana Raquel
dc.subject.spa.fl_str_mv automobile driving
cognition
Alzheimer's disease
dementia
topic automobile driving
cognition
Alzheimer's disease
dementia
description As life expectancy increases, there is a marked increase in the elderly population eager to continue driving. A large proportion of these elderly drive safely, however, patients with mild dementia are high-risk drivers. Objective: to identify the cognitive tests that best predict driving ability in subjects with mild dementia. Methods: 28 drivers with mild dementia and 28 healthy elderly subjects underwent an extensive cognitive assessment (NACC Uniform Data Set Neuropsychological Battery), completed an adapted On Road Driving Test (ORDT) and a Driving Simulator assessment. Results: drivers with mild dementia made more mistakes on the ORDT and had slower responses in the simulator tasks. Cognitive tests correlated strongly with on road and simulator driving performance. Age, the Digit Symbol Modalities Test and Boston Naming Test scores were the variables that best predicted performance on the ORDT and were included in a logistic regression model. Conclusion: the strong correlation between driving performance and performance on specific cognitive tests supports the importance of cognitive assessment as a useful tool for deciding whether patients with mild dementia can drive safely. The algorithm including these three variables could be used as a screening tool for the detection of unsafe driving in elderly subjects with cognitive decline.
publishDate 2019
dc.date.issued.none.fl_str_mv 2019
dc.date.accessioned.none.fl_str_mv 2020-11-24T16:29:02Z
dc.date.available.none.fl_str_mv 2020-11-24T16:29:02Z
dc.type.spa.fl_str_mv Artículo de revista
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dc.identifier.doi.spa.fl_str_mv http://dx.doi.org/10.1590/1980-57642018dn13-030008
dc.identifier.instname.spa.fl_str_mv Corporación Universidad de la Costa
dc.identifier.reponame.spa.fl_str_mv REDICUC - Repositorio CUC
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url https://hdl.handle.net/11323/7465
http://dx.doi.org/10.1590/1980-57642018dn13-030008
https://repositorio.cuc.edu.co/
identifier_str_mv Corporación Universidad de la Costa
REDICUC - Repositorio CUC
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.references.spa.fl_str_mv 1. Arizaga RL, Gogorza RE, Allegri RF, Baumann D, Morales de Barrios MC, Harris P, et al. Deterioro cognitivo en mayores de 60 años en Cañuelas (Argentina) Resultados del piloto del estudio ceibo (estudio epidemiológico poblacional de demencia) Rev Neurol Arg. 2005;30(2):83-90.
2. Iverson DJ, Gronseth GS, Reger MA, Classen S, Dubinsky RM, Rizzo M. QualityStandards Subcommittee of the American Academy of Neurology. Practice parameterupdate: evaluation and management of driving risk in dementia: report of theQuality Standards Subcommittee of the American Academy of Neurology. Neurology.2010;74(16):1316-24.
3. Edwards JD, Perkins M, Ross LA, Reynolds SL. Driving status and threeyear mortality among community-dwelling older adults. J Gerontol A Biol Sci Med Sci. 2009; 64(2):300-5.
4. Liddle J, Reaston T, Pachana N, Mitchell G, Gustafsson L. Is planning for driving cessation critical for the well-being and lifestyle of older drivers? Int Psychogeriatr. 2014;26(7):1111-20.
5. American Geriatrics Society & A. Pomidor, Ed. (2016, January). Clinician’s guide to assessing and counseling older drivers, 3rd edition. (Report No. DOT HS 812 228).Washington, DC: Chapter 3—Screening and Assessment of Functional Abilities for Driving. National Highway Traffic Safety Administration. Copyright retained by The American Geriatrics Society.
6. Iverson DJ, Gronseth GS, Reger MA, Classen S, Dubinsky RM, Rizzo M. Quality Standards Subcommittee of the American Academy of Neurology. Practice parameter update: evaluation and management of driving risk in dementia: report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 2010;74(16):1316-24.
7. Bédard M, Weaver B, Darzins P, Porter MM. Predicting driving performance in older adults: We are not there yet! Traffic Inj Prev. 2008;9(4): 336-41.
8. Baldock MRJ, Mathias J, McLean J, Berndt A. Visual attention as a predictor of on-road driving performance of older drivers. Aust J Psychol. 2007;59:159-68.
9. Barco PP, Wallendorf MJ, Snellgrove CA, Ott BR. Predicting road test performance in drivers with dementia. J Am Geriatr Soc. 2011;59: 2112-7.
10. Bieri R, Jäger M, Gruber N, Nef T, Müri RM, Mosimann UP. A novel computer test to assess driving-relevant cognitive functions--a pilot study. Int Psychogeriatr. 2014;26(2):229-38.
11. Mathias JL, Lucas LK. Cognitive predictors of unsafe driving in older drivers: a meta-analysis. Int Psychogeriatr. 2009;21(4):637-53.
12. Grillo R, Mangone CA. “Desarrollo de batería neuropsicológica sensible para predecir el rendimiento en la Conducción de vehículos en adultos mayores de 55 años” Vertex 2007; XVIII: 473-9.
13. ZuinDR, RecchiaL,BarbosaA, Ortiz, H. Utilidad de una Batería Neuropsicológica Breve (BNB) en el Screening de Deterioro Cognitivo en Pacientes que Mantienen el Hábito de Manejo Vehicular. Neurol Arg. 2008;33:28-32.
14. McKhann G, Drachman D, Folstein M et al. Clinical Diagnosis of Alzheimer’s Disease: Report of the NINCDS-ADRA work group under the auspices of the Department of Health and Human Service Task Force on Alzheimer’s Disease. Neurology 1984;34:939-44.
15. Morris JC. The Clinical Dementia Rating (CDR). Current Version and Scoring Rules. Neurology 1994;44:1983-4.
16. Benson G, de Felipe J , Xiaodong L, Sanoa M. Performance of Spanishspeaking community-dwelling elders in the United States on the Uniform Data Set. Alzheimers Dement. 2014;10(0):S338-S343.
17. Morris JC, Weintraub S, Chui HC, Cummings J, Decarli C, Ferris S, et al. The Uniform Data Set (UDS): clinical and cognitive variables and descriptive data from Alzheimer Disease Centers. Alzheimer Dis Assoc Disord. 2006;20(4):210-6
18. Folstein MF, Folstein SE, McHugh PR. Mini-Mental State: a practical method for grading the cognitive state of patients for the physician. J Psychiatr Res. 1975;12:189-98.
19. Wechsler, D. Wechsler Memory Scale-Revised Manual. Psychological Corporation; San Antonio, TX; 1987.
20. Wechsler, D. The Wechsler Adult Intelligence Scale-Revised. Psychological Corporation; New York, NY; 1981.
21. Morris JC, Heyman A, Mohs RC, Hughes JP, van Belle G, Fillenbaum G, et al. The Consortium to establish a registry for Alzheimer’s Disease (CERAD). Part I. Clinical and neuropsychological assessment of Alzheimer’s disease. Neurology. 1989;39:1159-65.
22. Kaplan E, Goodglass H, Weintraub S. Test de Vocabulario de Boston [Boston Naming Test]. Editorial Médica Panamericana; Madrid, Spain; 1996.
23. Adjutant General’s Office. Army individual test battery manual of directions and scoring. War Department, Adjutant General’s Office; Washington DC; 1944.
24. Lezak MD. Neuropsychological Assessment, 3er ed. New York : Oxford University Press; 1995.
25. Goodglass H, Kaplan E. The Assessment of Aphasia and Related Disorders. Philadelphia: Lea & Febiger; 1983.
26. Dubois B, Slachevsky A, Litvan I, Pillon B. The FAB: a Frontal Assessment Battery at bedside. Neurology. 2000;55(11):1621-6.
27. Kaufer DI, Cummings JL, Ketchel P, Smith V, MacMillan A, Shelley, et al. Validation of the NPI-Q, a brief clinical form of the Neuropsychiatric Inventory. J Neuropsychiatry Clin Neurosci. 2000;12(2):233-9.
28. Pfeffer RI, Kurosaki TT, Harrah CH, Chance JM, Filos S. Measurement of functional activities in older adults in the community. J Gerontol. 1982;37(3):323-9.
29. Galvin JE, Roe CM, Xiong C, Morris JC. Validity and reliability of the AD8 informant interview in dementia. Neurology. 2006;67(11):1942-8.
30. Dawson JD, Anderson SW, Uc EY, Dastrup E, Rizzo M. Predictors of driving safety in early Alzheimer disease. Neurology. 2009;72(6):521-7.
31. Ott BR, Heindel WC, Papandonatos GD, Festa EK, Davis JD, Daiello LA, et al. A longitudinal study of drivers with Alzheimer disease. Neurology. 2008;70(14):1171-8.
32. Duchek JM, Carr DB, Hunt L, Roe CM, Xiong C, Shah K, et al. Longitudinal driving performance in early-stage dementia of the Alzheimer type. J Am Geriatr Soc. 2003; 51(10):1342-7.
33. Iverson DJ, Gronseth GS, Reger MA, Classen S, Dubinsky RM, Rizzo M. Quality Standards Subcommittee of the American Academy of Neurology. Practice parameter update: evaluation and management of driving risk in dementia: report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 201074(16):1316-24.
34. Bixby K, Davis JD, Ott BR. Comparing caregiver and clinician predictions of fitness to drive in people with Alzheimer’s disease. Am J Occup Ther.2015;69(3):6903270030 p1-7.
35. Wild K, Cotrell V. Identifying driving impairment in Alzheimer disease: a comparison of self and observer reports versus driving evaluation. Alzheimer Dis Assoc Disord. 2003;17(1):27-34.
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spelling Crivelli, LucíaJulieta Russo, MaríaFranco Farez, MauricioBonetto, MarianaPrado, CeciliaCalandri, Ismael LuisCampos, JorgeCohen, GabrielaChrem Mendez, PatricioSabe, Liliana Raquel2020-11-24T16:29:02Z2020-11-24T16:29:02Z2019https://hdl.handle.net/11323/7465http://dx.doi.org/10.1590/1980-57642018dn13-030008Corporación Universidad de la CostaREDICUC - Repositorio CUChttps://repositorio.cuc.edu.co/As life expectancy increases, there is a marked increase in the elderly population eager to continue driving. A large proportion of these elderly drive safely, however, patients with mild dementia are high-risk drivers. Objective: to identify the cognitive tests that best predict driving ability in subjects with mild dementia. Methods: 28 drivers with mild dementia and 28 healthy elderly subjects underwent an extensive cognitive assessment (NACC Uniform Data Set Neuropsychological Battery), completed an adapted On Road Driving Test (ORDT) and a Driving Simulator assessment. Results: drivers with mild dementia made more mistakes on the ORDT and had slower responses in the simulator tasks. Cognitive tests correlated strongly with on road and simulator driving performance. Age, the Digit Symbol Modalities Test and Boston Naming Test scores were the variables that best predicted performance on the ORDT and were included in a logistic regression model. Conclusion: the strong correlation between driving performance and performance on specific cognitive tests supports the importance of cognitive assessment as a useful tool for deciding whether patients with mild dementia can drive safely. The algorithm including these three variables could be used as a screening tool for the detection of unsafe driving in elderly subjects with cognitive decline.Crivelli, LucíaJulieta Russo, MaríaFranco Farez, MauricioBonetto, MarianaPrado, CeciliaCalandri, Ismael LuisCampos, JorgeCohen, GabrielaChrem Mendez, Patricio-will be generated-orcid-0000-0002-6790-6566-600Sabe, Liliana Raquelapplication/pdfengCorporación Universidad de la CostaAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Dementia & Neuropsychologiahttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642019000300312&tlng=enautomobile drivingcognitionAlzheimer's diseasedementiaDriving and Alzheimer's disease: A neuropsychological screening battery for the elderlyCONDUÇÃO E DOENÇA DE ALZHEIMER: UMA BATERIA DE TRIAGEM NEUROPSICOLÓGICA PARA IDOSOSArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/acceptedVersion1. Arizaga RL, Gogorza RE, Allegri RF, Baumann D, Morales de Barrios MC, Harris P, et al. Deterioro cognitivo en mayores de 60 años en Cañuelas (Argentina) Resultados del piloto del estudio ceibo (estudio epidemiológico poblacional de demencia) Rev Neurol Arg. 2005;30(2):83-90.2. Iverson DJ, Gronseth GS, Reger MA, Classen S, Dubinsky RM, Rizzo M. QualityStandards Subcommittee of the American Academy of Neurology. Practice parameterupdate: evaluation and management of driving risk in dementia: report of theQuality Standards Subcommittee of the American Academy of Neurology. Neurology.2010;74(16):1316-24.3. Edwards JD, Perkins M, Ross LA, Reynolds SL. Driving status and threeyear mortality among community-dwelling older adults. J Gerontol A Biol Sci Med Sci. 2009; 64(2):300-5.4. Liddle J, Reaston T, Pachana N, Mitchell G, Gustafsson L. Is planning for driving cessation critical for the well-being and lifestyle of older drivers? Int Psychogeriatr. 2014;26(7):1111-20.5. American Geriatrics Society & A. Pomidor, Ed. (2016, January). Clinician’s guide to assessing and counseling older drivers, 3rd edition. (Report No. DOT HS 812 228).Washington, DC: Chapter 3—Screening and Assessment of Functional Abilities for Driving. National Highway Traffic Safety Administration. Copyright retained by The American Geriatrics Society.6. Iverson DJ, Gronseth GS, Reger MA, Classen S, Dubinsky RM, Rizzo M. Quality Standards Subcommittee of the American Academy of Neurology. Practice parameter update: evaluation and management of driving risk in dementia: report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 2010;74(16):1316-24.7. Bédard M, Weaver B, Darzins P, Porter MM. Predicting driving performance in older adults: We are not there yet! Traffic Inj Prev. 2008;9(4): 336-41.8. Baldock MRJ, Mathias J, McLean J, Berndt A. Visual attention as a predictor of on-road driving performance of older drivers. Aust J Psychol. 2007;59:159-68.9. Barco PP, Wallendorf MJ, Snellgrove CA, Ott BR. Predicting road test performance in drivers with dementia. J Am Geriatr Soc. 2011;59: 2112-7.10. Bieri R, Jäger M, Gruber N, Nef T, Müri RM, Mosimann UP. A novel computer test to assess driving-relevant cognitive functions--a pilot study. Int Psychogeriatr. 2014;26(2):229-38.11. Mathias JL, Lucas LK. Cognitive predictors of unsafe driving in older drivers: a meta-analysis. Int Psychogeriatr. 2009;21(4):637-53.12. Grillo R, Mangone CA. “Desarrollo de batería neuropsicológica sensible para predecir el rendimiento en la Conducción de vehículos en adultos mayores de 55 años” Vertex 2007; XVIII: 473-9.13. ZuinDR, RecchiaL,BarbosaA, Ortiz, H. Utilidad de una Batería Neuropsicológica Breve (BNB) en el Screening de Deterioro Cognitivo en Pacientes que Mantienen el Hábito de Manejo Vehicular. Neurol Arg. 2008;33:28-32.14. McKhann G, Drachman D, Folstein M et al. Clinical Diagnosis of Alzheimer’s Disease: Report of the NINCDS-ADRA work group under the auspices of the Department of Health and Human Service Task Force on Alzheimer’s Disease. Neurology 1984;34:939-44.15. Morris JC. The Clinical Dementia Rating (CDR). Current Version and Scoring Rules. Neurology 1994;44:1983-4.16. Benson G, de Felipe J , Xiaodong L, Sanoa M. Performance of Spanishspeaking community-dwelling elders in the United States on the Uniform Data Set. Alzheimers Dement. 2014;10(0):S338-S343.17. Morris JC, Weintraub S, Chui HC, Cummings J, Decarli C, Ferris S, et al. The Uniform Data Set (UDS): clinical and cognitive variables and descriptive data from Alzheimer Disease Centers. Alzheimer Dis Assoc Disord. 2006;20(4):210-618. Folstein MF, Folstein SE, McHugh PR. Mini-Mental State: a practical method for grading the cognitive state of patients for the physician. J Psychiatr Res. 1975;12:189-98.19. Wechsler, D. Wechsler Memory Scale-Revised Manual. Psychological Corporation; San Antonio, TX; 1987.20. Wechsler, D. The Wechsler Adult Intelligence Scale-Revised. Psychological Corporation; New York, NY; 1981.21. Morris JC, Heyman A, Mohs RC, Hughes JP, van Belle G, Fillenbaum G, et al. The Consortium to establish a registry for Alzheimer’s Disease (CERAD). Part I. Clinical and neuropsychological assessment of Alzheimer’s disease. Neurology. 1989;39:1159-65.22. Kaplan E, Goodglass H, Weintraub S. Test de Vocabulario de Boston [Boston Naming Test]. Editorial Médica Panamericana; Madrid, Spain; 1996.23. Adjutant General’s Office. Army individual test battery manual of directions and scoring. War Department, Adjutant General’s Office; Washington DC; 1944.24. Lezak MD. Neuropsychological Assessment, 3er ed. New York : Oxford University Press; 1995.25. Goodglass H, Kaplan E. The Assessment of Aphasia and Related Disorders. Philadelphia: Lea & Febiger; 1983.26. Dubois B, Slachevsky A, Litvan I, Pillon B. The FAB: a Frontal Assessment Battery at bedside. Neurology. 2000;55(11):1621-6.27. Kaufer DI, Cummings JL, Ketchel P, Smith V, MacMillan A, Shelley, et al. Validation of the NPI-Q, a brief clinical form of the Neuropsychiatric Inventory. J Neuropsychiatry Clin Neurosci. 2000;12(2):233-9.28. Pfeffer RI, Kurosaki TT, Harrah CH, Chance JM, Filos S. Measurement of functional activities in older adults in the community. J Gerontol. 1982;37(3):323-9.29. Galvin JE, Roe CM, Xiong C, Morris JC. Validity and reliability of the AD8 informant interview in dementia. Neurology. 2006;67(11):1942-8.30. Dawson JD, Anderson SW, Uc EY, Dastrup E, Rizzo M. Predictors of driving safety in early Alzheimer disease. Neurology. 2009;72(6):521-7.31. Ott BR, Heindel WC, Papandonatos GD, Festa EK, Davis JD, Daiello LA, et al. A longitudinal study of drivers with Alzheimer disease. Neurology. 2008;70(14):1171-8.32. Duchek JM, Carr DB, Hunt L, Roe CM, Xiong C, Shah K, et al. Longitudinal driving performance in early-stage dementia of the Alzheimer type. J Am Geriatr Soc. 2003; 51(10):1342-7.33. Iverson DJ, Gronseth GS, Reger MA, Classen S, Dubinsky RM, Rizzo M. Quality Standards Subcommittee of the American Academy of Neurology. Practice parameter update: evaluation and management of driving risk in dementia: report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 201074(16):1316-24.34. Bixby K, Davis JD, Ott BR. Comparing caregiver and clinician predictions of fitness to drive in people with Alzheimer’s disease. Am J Occup Ther.2015;69(3):6903270030 p1-7.35. Wild K, Cotrell V. Identifying driving impairment in Alzheimer disease: a comparison of self and observer reports versus driving evaluation. 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