Cost and effectivennes of a screening algorithm for the diagnosis of rheumatoid arthirits
Objectives Rheumatoid arthritis (RA) is a chronic, progressive autoimmune systemic disease affecting roughly 0.7% of the global population. According to direct medical costs, RA has an important economic burden worldwide. We aimed to describe the proportion of patients with a correct or wrong diagno...
- Autores:
-
Santos-Moreno, P
Buitrago-Garcia, D
Villarreal, L
Alvis-Zakzuk, N
Carrasquilla, M
Alvis Guzman, N
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2018
- Institución:
- Corporación Universidad de la Costa
- Repositorio:
- REDICUC - Repositorio CUC
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.cuc.edu.co:11323/4708
- Acceso en línea:
- https://hdl.handle.net/11323/4708
https://repositorio.cuc.edu.co/
- Palabra clave:
- Artritis reumatoide
Enfermedad sistémica autoinmune crónica y progresiva
Pacientes
Carga económica
Rheumatoid arthritis
Chronic and progressive autoimmune systemic disease
Patients
Economic load
- Rights
- openAccess
- License
- Attribution-NonCommercial-ShareAlike 4.0 International
id |
RCUC2_c8808b5bd9cb141dd3c38a9a5732283d |
---|---|
oai_identifier_str |
oai:repositorio.cuc.edu.co:11323/4708 |
network_acronym_str |
RCUC2 |
network_name_str |
REDICUC - Repositorio CUC |
repository_id_str |
|
dc.title.spa.fl_str_mv |
Cost and effectivennes of a screening algorithm for the diagnosis of rheumatoid arthirits |
dc.title.translated.spa.fl_str_mv |
Costo y eficacia de un algoritmo de detección para el diagnóstico de la artritis reumatoide |
title |
Cost and effectivennes of a screening algorithm for the diagnosis of rheumatoid arthirits |
spellingShingle |
Cost and effectivennes of a screening algorithm for the diagnosis of rheumatoid arthirits Artritis reumatoide Enfermedad sistémica autoinmune crónica y progresiva Pacientes Carga económica Rheumatoid arthritis Chronic and progressive autoimmune systemic disease Patients Economic load |
title_short |
Cost and effectivennes of a screening algorithm for the diagnosis of rheumatoid arthirits |
title_full |
Cost and effectivennes of a screening algorithm for the diagnosis of rheumatoid arthirits |
title_fullStr |
Cost and effectivennes of a screening algorithm for the diagnosis of rheumatoid arthirits |
title_full_unstemmed |
Cost and effectivennes of a screening algorithm for the diagnosis of rheumatoid arthirits |
title_sort |
Cost and effectivennes of a screening algorithm for the diagnosis of rheumatoid arthirits |
dc.creator.fl_str_mv |
Santos-Moreno, P Buitrago-Garcia, D Villarreal, L Alvis-Zakzuk, N Carrasquilla, M Alvis Guzman, N |
dc.contributor.author.spa.fl_str_mv |
Santos-Moreno, P Buitrago-Garcia, D Villarreal, L Alvis-Zakzuk, N Carrasquilla, M Alvis Guzman, N |
dc.subject.spa.fl_str_mv |
Artritis reumatoide Enfermedad sistémica autoinmune crónica y progresiva Pacientes Carga económica Rheumatoid arthritis Chronic and progressive autoimmune systemic disease Patients Economic load |
topic |
Artritis reumatoide Enfermedad sistémica autoinmune crónica y progresiva Pacientes Carga económica Rheumatoid arthritis Chronic and progressive autoimmune systemic disease Patients Economic load |
description |
Objectives Rheumatoid arthritis (RA) is a chronic, progressive autoimmune systemic disease affecting roughly 0.7% of the global population. According to direct medical costs, RA has an important economic burden worldwide. We aimed to describe the proportion of patients with a correct or wrong diagnosis of RA when an algorithm of disease diagnosis was applied. Also, we estimated the costs-savings associated with the correct diagnosis of the disease. Methods We performed a descriptive analysis of patients who were referred from primary care centers to a RA specialized one with presumptive diagnosis of RA. Each patient was evaluated to confirm or rule-out diagnosis of RA as follows: a rheumatologist fulfilled a complete musculoskeletal examination; it was assessed rheumatoid factor, anti-citrullinated antibodies and other laboratories depending on each case. Also, x-rays of hands/feet were made, and in cases of persistent doubt about the diagnosis, MRI of hands/feet, and/or ultrasound of hands/feet were requested. Descriptive epidemiology was done. We assessed the overall drug expenses related to correct diagnosis of RA. Costs were presented in US dollars at the official rate of exchange for December 2017. Results 1415 patients were evaluated during a 12-month period. After applying the diagnosis algorithm 45% of patients had confirmed RA, while 55% had other diagnosis mainly osteoarthritis. When we calculated the cost-savings related to the adequate diagnosis of RA we saved USD1.300 per patient/year regarding to the following cost items: drugs, medical services and diagnostic control tests. For all diagnosed patients (765) we saved USD$994.500 in twelve months. Conclusions Implementing a clear route to diagnose patients with presumptive RA reduces diagnostic errors, and at the same time it saves a large amount of money for the Colombian health system. Policy-makers should focus on implementing management routes for the adequate patient classification from primary care centers. |
publishDate |
2018 |
dc.date.issued.none.fl_str_mv |
2018 |
dc.date.accessioned.none.fl_str_mv |
2019-05-27T13:10:12Z |
dc.date.available.none.fl_str_mv |
2019-05-27T13:10:12Z |
dc.type.spa.fl_str_mv |
Artículo de revista |
dc.type.coar.fl_str_mv |
http://purl.org/coar/resource_type/c_2df8fbb1 |
dc.type.coar.spa.fl_str_mv |
http://purl.org/coar/resource_type/c_6501 |
dc.type.content.spa.fl_str_mv |
Text |
dc.type.driver.spa.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.redcol.spa.fl_str_mv |
http://purl.org/redcol/resource_type/ART |
dc.type.version.spa.fl_str_mv |
info:eu-repo/semantics/acceptedVersion |
format |
http://purl.org/coar/resource_type/c_6501 |
status_str |
acceptedVersion |
dc.identifier.uri.spa.fl_str_mv |
https://hdl.handle.net/11323/4708 |
dc.identifier.instname.spa.fl_str_mv |
Corporación Universidad de la Costa |
dc.identifier.reponame.spa.fl_str_mv |
REDICUC - Repositorio CUC |
dc.identifier.repourl.spa.fl_str_mv |
https://repositorio.cuc.edu.co/ |
url |
https://hdl.handle.net/11323/4708 https://repositorio.cuc.edu.co/ |
identifier_str_mv |
Corporación Universidad de la Costa REDICUC - Repositorio CUC |
dc.language.iso.none.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.spa.fl_str_mv |
https://doi.org/10.1016/j.jval.2018.04.867 |
dc.rights.spa.fl_str_mv |
Attribution-NonCommercial-ShareAlike 4.0 International |
dc.rights.uri.spa.fl_str_mv |
http://creativecommons.org/licenses/by-nc-sa/4.0/ |
dc.rights.accessrights.spa.fl_str_mv |
info:eu-repo/semantics/openAccess |
dc.rights.coar.spa.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 |
rights_invalid_str_mv |
Attribution-NonCommercial-ShareAlike 4.0 International http://creativecommons.org/licenses/by-nc-sa/4.0/ http://purl.org/coar/access_right/c_abf2 |
eu_rights_str_mv |
openAccess |
dc.publisher.spa.fl_str_mv |
Value in health 21 |
institution |
Corporación Universidad de la Costa |
bitstream.url.fl_str_mv |
https://repositorio.cuc.edu.co/bitstreams/12db19f3-8240-4d7a-aee5-b17ddae3c8ec/download https://repositorio.cuc.edu.co/bitstreams/19388578-777a-42cf-af03-ae11661c7182/download https://repositorio.cuc.edu.co/bitstreams/ca186528-2f30-467f-8777-62e5dcc4f3ea/download https://repositorio.cuc.edu.co/bitstreams/c97c8a70-d16f-47ab-832e-15258a8720df/download https://repositorio.cuc.edu.co/bitstreams/6f12e9d9-3770-44ea-b88b-ba544e587e70/download |
bitstream.checksum.fl_str_mv |
f055e1e155c9de4f603330c30800a816 934f4ca17e109e0a05eaeaba504d7ce4 8a4605be74aa9ea9d79846c1fba20a33 980e78734c6a292c7ce1cdffaee45b19 f5cb72bb6b57bba32334be3d910c90ff |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 MD5 MD5 |
repository.name.fl_str_mv |
Repositorio de la Universidad de la Costa CUC |
repository.mail.fl_str_mv |
repdigital@cuc.edu.co |
_version_ |
1828166741272821760 |
spelling |
Santos-Moreno, PBuitrago-Garcia, DVillarreal, LAlvis-Zakzuk, NCarrasquilla, MAlvis Guzman, N2019-05-27T13:10:12Z2019-05-27T13:10:12Z2018https://hdl.handle.net/11323/4708Corporación Universidad de la CostaREDICUC - Repositorio CUChttps://repositorio.cuc.edu.co/Objectives Rheumatoid arthritis (RA) is a chronic, progressive autoimmune systemic disease affecting roughly 0.7% of the global population. According to direct medical costs, RA has an important economic burden worldwide. We aimed to describe the proportion of patients with a correct or wrong diagnosis of RA when an algorithm of disease diagnosis was applied. Also, we estimated the costs-savings associated with the correct diagnosis of the disease. Methods We performed a descriptive analysis of patients who were referred from primary care centers to a RA specialized one with presumptive diagnosis of RA. Each patient was evaluated to confirm or rule-out diagnosis of RA as follows: a rheumatologist fulfilled a complete musculoskeletal examination; it was assessed rheumatoid factor, anti-citrullinated antibodies and other laboratories depending on each case. Also, x-rays of hands/feet were made, and in cases of persistent doubt about the diagnosis, MRI of hands/feet, and/or ultrasound of hands/feet were requested. Descriptive epidemiology was done. We assessed the overall drug expenses related to correct diagnosis of RA. Costs were presented in US dollars at the official rate of exchange for December 2017. Results 1415 patients were evaluated during a 12-month period. After applying the diagnosis algorithm 45% of patients had confirmed RA, while 55% had other diagnosis mainly osteoarthritis. When we calculated the cost-savings related to the adequate diagnosis of RA we saved USD1.300 per patient/year regarding to the following cost items: drugs, medical services and diagnostic control tests. For all diagnosed patients (765) we saved USD$994.500 in twelve months. Conclusions Implementing a clear route to diagnose patients with presumptive RA reduces diagnostic errors, and at the same time it saves a large amount of money for the Colombian health system. Policy-makers should focus on implementing management routes for the adequate patient classification from primary care centers.Los objetivos La artritis reumatoide (AR) es una enfermedad sistémica autoinmune crónica y progresiva que afecta a aproximadamente el 0,7% de la población mundial. Según los costos médicos directos, la AR tiene una importante carga económica en todo el mundo. El objetivo fue describir la proporción de pacientes con un diagnóstico correcto o incorrecto de AR cuando se aplicó un algoritmo de diagnóstico de enfermedad. Además, calculamos los ahorros en costos asociados con el diagnóstico correcto de la enfermedad. Los metodos Se realizó un análisis descriptivo de los pacientes que fueron remitidos de los centros de atención primaria a uno especializado en AR con diagnóstico presuntivo de AR. Cada paciente fue evaluado para confirmar o descartar el diagnóstico de AR de la siguiente manera: un reumatólogo realizó un examen musculoesquelético completo; Se evaluó el factor reumatoide, los anticuerpos anti-citrulinados y otros laboratorios según cada caso. Además, se realizaron radiografías de manos / pies y, en casos de dudas persistentes sobre el diagnóstico, se solicitaron IRM de manos / pies y / o ecografía de manos / pies. Se realizó epidemiología descriptiva. Se evaluaron los gastos generales de medicamentos relacionados con el diagnóstico correcto de la AR. Los costos se presentaron en dólares estadounidenses al tipo de cambio oficial de diciembre de 2017. Resultados 1415 pacientes fueron evaluados durante un período de 12 meses. Después de aplicar el algoritmo de diagnóstico, el 45% de los pacientes tenían AR confirmada, mientras que el 55% tenía otro diagnóstico, principalmente osteoartritis. Cuando calculamos los ahorros de costos relacionados con el diagnóstico adecuado de la AR, ahorramos USD 1,300 por paciente / año con respecto a los siguientes artículos de costos: medicamentos, servicios médicos y pruebas de control de diagnóstico. Para todos los pacientes diagnosticados (765), ahorramos USD $ 994.500 en doce meses. Conclusiones Implementar una ruta clara para diagnosticar a los pacientes con AR presunta reduce los errores de diagnóstico y, al mismo tiempo, ahorra una gran cantidad de dinero para el sistema de salud colombiano. Los responsables de la formulación de políticas deberían centrarse en implementar rutas de gestión para la clasificación adecuada de pacientes en los centros de atención primaria.Santos-Moreno, P-4c8bf522-fd2f-4d0d-bd00-433bf39bccbf-0Buitrago-Garcia, D-f72f35bb-b832-4224-b846-95d3948c1509-0Villarreal, L-0e7db4bd-aaff-42eb-b6c7-f475dbb3fe50-0Alvis-Zakzuk, N-4ad43f03-69e9-4fe7-b60d-070645964218-0Carrasquilla, M-c777b5bf-3e08-468d-9bb7-9fdd4a8f5e28-0Alvis Guzman, N-2d13fafb-f99f-45da-90f0-c24f33bc4418-0engValue in health 21https://doi.org/10.1016/j.jval.2018.04.867Attribution-NonCommercial-ShareAlike 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-sa/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Artritis reumatoideEnfermedad sistémica autoinmune crónica y progresivaPacientesCarga económicaRheumatoid arthritisChronic and progressive autoimmune systemic diseasePatientsEconomic loadCost and effectivennes of a screening algorithm for the diagnosis of rheumatoid arthiritsCosto y eficacia de un algoritmo de detección para el diagnóstico de la artritis reumatoideArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/acceptedVersionPublicationORIGINALCost and Effectivennes of a Screening Algorithm for the Diagnosis.pdfCost and Effectivennes of a Screening Algorithm for the Diagnosis.pdfapplication/pdf69440https://repositorio.cuc.edu.co/bitstreams/12db19f3-8240-4d7a-aee5-b17ddae3c8ec/downloadf055e1e155c9de4f603330c30800a816MD51CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-81031https://repositorio.cuc.edu.co/bitstreams/19388578-777a-42cf-af03-ae11661c7182/download934f4ca17e109e0a05eaeaba504d7ce4MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://repositorio.cuc.edu.co/bitstreams/ca186528-2f30-467f-8777-62e5dcc4f3ea/download8a4605be74aa9ea9d79846c1fba20a33MD53THUMBNAILCost and Effectivennes of a Screening Algorithm for the Diagnosis.pdf.jpgCost and Effectivennes of a Screening Algorithm for the Diagnosis.pdf.jpgimage/jpeg85847https://repositorio.cuc.edu.co/bitstreams/c97c8a70-d16f-47ab-832e-15258a8720df/download980e78734c6a292c7ce1cdffaee45b19MD55TEXTCost and Effectivennes of a Screening Algorithm for the Diagnosis.pdf.txtCost and Effectivennes of a Screening Algorithm for the Diagnosis.pdf.txttext/plain12992https://repositorio.cuc.edu.co/bitstreams/6f12e9d9-3770-44ea-b88b-ba544e587e70/downloadf5cb72bb6b57bba32334be3d910c90ffMD5611323/4708oai:repositorio.cuc.edu.co:11323/47082024-09-17 12:46:45.899http://creativecommons.org/licenses/by-nc-sa/4.0/Attribution-NonCommercial-ShareAlike 4.0 Internationalopen.accesshttps://repositorio.cuc.edu.coRepositorio de la Universidad de la Costa CUCrepdigital@cuc.edu.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 |