Social cognition in early multiple sclerosis: neuropsychological and anatomical approach
Cognitive impairment and deficits in Social Cognition (SC) are frequent in patients with Multiple Sclerosis (MS). The aim of the present work is to study SC in patients with early MS and to analyze its neuroanatomical correlation. Thirty-four patients with relapsing remitting MS, with ≤ 2 years of d...
- Autores:
-
Crivelli, Lucía
Calandri, Ismael Luis
Helou, Belén
Keller, Greta
Fiol, Marcela Paula
Ysraelit, María-Célica
Gaitán, María-Inés
Correale, Jorge
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2021
- Institución:
- Corporación Universidad de la Costa
- Repositorio:
- REDICUC - Repositorio CUC
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.cuc.edu.co:11323/10133
- Acceso en línea:
- https://hdl.handle.net/11323/10133
https://repositorio.cuc.edu.co/
- Palabra clave:
- Cognitive dysfunction
Social cognition
Multiple sclerosis
Neuropsychological test
Disease progression
Disfunción cognitiva
Cognición social
Esclerosis múltiple
Test neuropsicológico
Progresión de la enfermedad
- Rights
- openAccess
- License
- Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)
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Social cognition in early multiple sclerosis: neuropsychological and anatomical approach |
| dc.title.translated.none.fl_str_mv |
La cognición social en la esclerosis múltiple temprana: enfoque neuropsicológico y anatómico |
| title |
Social cognition in early multiple sclerosis: neuropsychological and anatomical approach |
| spellingShingle |
Social cognition in early multiple sclerosis: neuropsychological and anatomical approach Cognitive dysfunction Social cognition Multiple sclerosis Neuropsychological test Disease progression Disfunción cognitiva Cognición social Esclerosis múltiple Test neuropsicológico Progresión de la enfermedad |
| title_short |
Social cognition in early multiple sclerosis: neuropsychological and anatomical approach |
| title_full |
Social cognition in early multiple sclerosis: neuropsychological and anatomical approach |
| title_fullStr |
Social cognition in early multiple sclerosis: neuropsychological and anatomical approach |
| title_full_unstemmed |
Social cognition in early multiple sclerosis: neuropsychological and anatomical approach |
| title_sort |
Social cognition in early multiple sclerosis: neuropsychological and anatomical approach |
| dc.creator.fl_str_mv |
Crivelli, Lucía Calandri, Ismael Luis Helou, Belén Keller, Greta Fiol, Marcela Paula Ysraelit, María-Célica Gaitán, María-Inés Correale, Jorge |
| dc.contributor.author.none.fl_str_mv |
Crivelli, Lucía Calandri, Ismael Luis Helou, Belén Keller, Greta Fiol, Marcela Paula Ysraelit, María-Célica Gaitán, María-Inés Correale, Jorge |
| dc.subject.proposal.eng.fl_str_mv |
Cognitive dysfunction Social cognition Multiple sclerosis Neuropsychological test Disease progression |
| topic |
Cognitive dysfunction Social cognition Multiple sclerosis Neuropsychological test Disease progression Disfunción cognitiva Cognición social Esclerosis múltiple Test neuropsicológico Progresión de la enfermedad |
| dc.subject.proposal.spa.fl_str_mv |
Disfunción cognitiva Cognición social Esclerosis múltiple Test neuropsicológico Progresión de la enfermedad |
| description |
Cognitive impairment and deficits in Social Cognition (SC) are frequent in patients with Multiple Sclerosis (MS). The aim of the present work is to study SC in patients with early MS and to analyze its neuroanatomical correlation. Thirty-four patients with relapsing remitting MS, with ≤ 2 years of disease progression and EDSS and ≤ 2, and 30 healthy control subjects matched for age, sex, and educational level were recruited. Subjects performed a comprehensive neuropsychological assessment (Rao BRB). SC was assessed using the International Affective Picture System IAPS, The Eyes in the Mind Test, the Empathy Quotient, and the Faux Pas Test. The anatomical correlation of patients with deficits in social cognition was studied through brain MRI and voxel-based morphometric for which cortical reconstruction and volumetric segmentation were performed using Freesurfer processing software. Patients showed significant deficits in executive functions, verbal memory and language tests. SC assessment showed that patients presented greater difficulties in the Faux Pas Test (p = 0.023), The Mind in the Eyes Test (p = 0.014), and presented a positive bias in the interpretation of neutral images of the IAPS (P = 0.023). Furthermore, patients with CS deficits presented less cortical thickness in areas of the right supramarginal gyrus, pars opercularis, and anterior cingulum. |
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2021 |
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2021-03-27 |
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2023-05-15T13:09:09Z |
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2023-05-15T13:09:09Z |
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Artículo de revista |
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Crivelli, L., Calandri, I.-L., Helou, B., Keller, G., Fiol, M.-P., Ysraelit, M.-C., Gaitan, M.-I., & Correale, J. (2021). Social Cognition In Early Multiple Sclerosis: Neuropsychological And Anatomical Approach: Cognición Social En La Esclerosis Múltiple Temprana: Enfoque Neuropsicológico Y Anatómico. Journal of Applied Cognitive Neuroscience, 2(1), e00153735. https://doi.org/10.17981/JACN.2.1.2021.03 |
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https://hdl.handle.net/11323/10133 |
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10.17981/JACN.2.1.2021.03 |
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2745-0031 |
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Corporación Universidad de la Costa |
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REDICUC – Repositorio CUC |
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Crivelli, L., Calandri, I.-L., Helou, B., Keller, G., Fiol, M.-P., Ysraelit, M.-C., Gaitan, M.-I., & Correale, J. (2021). Social Cognition In Early Multiple Sclerosis: Neuropsychological And Anatomical Approach: Cognición Social En La Esclerosis Múltiple Temprana: Enfoque Neuropsicológico Y Anatómico. Journal of Applied Cognitive Neuroscience, 2(1), e00153735. https://doi.org/10.17981/JACN.2.1.2021.03 10.17981/JACN.2.1.2021.03 2745-0031 Corporación Universidad de la Costa REDICUC – Repositorio CUC |
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eng |
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Journal of Applied Cognitive Neuroscience |
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Apps, M. A.; Rushworth, M. F. & Chang, S. W. (2016). The Anterior Cingulate Gyrus and Social Cognition: Tracking the Motivation of Others. Neuron, 90(4), 692–707. https://doi.org/10.1016/j.neuron.2016.04.018 Banati, M.; Sandor, J.; Mike A.; Illes, E.; Bors, L.; Feldmann, A.; Herold, R. & Illes, Z. (2010). Social cognition and Theory of Mind in patients with relapsing-remitting multiple sclerosis. Europena Journal of Neurology, 17(3), 426–433. https://doi.org/10.1111/j.1468-1331.2009.02836.x Baron-Cohen, S. & Wheelwright, S. (2004). The Empathy Quotient: An Investigation Of Adults With Asperger Syndrome Or High Functioning Autism, And NormalSex Differences, Journal of Autism and Developmental Disorders, 34(2), 163–175. https://doi.org/10.1023/b:jadd.0000022607.19833.00 Batista, S.; D’Almeida, O. C.; Afonso, A.; Freitas, S.; Macário, C.; Sousa, L.; Castelo-Branco, M.; Santana, I. & Cunha, L. (2017). Impairment of social cognition in multiple sclerosis: Amygdala atrophy is the main predictor. Multiple Sclerosis Journal, 23(10), 1358–1366. https://doi.org/10.1177/1352458516680750 Bradley, M. & Lang, P. (1994). Measuring emotion: The self-assessment manikin and the semantic differential. Journal of Behavior Therapy and Experimental Psychiatry, 25(1), 49–59. https://doi.org/10.1016/0005-7916(94)90063-9 Cáceres, F.; Vanotti, S.; Rao, S. & RECONEM Workgroup. (2011). Epidemiological characteristics of cognitive impairment of multiple sclerosis patients in a Latin American country. Journal of Clinical and Experimental Neuropsychology, 33(10), 1094–1098. https://doi.org/10.1080/13803395.2011.603690 Calder, A. J.; Keane, J.; Lawrence, A. D. & Manes F. (2004). Impaired recognition of anger following damage to the ventral striatum. Brain: a journal of Neulogy, 127(Pt 9), 1958–1969. https://doi.org/10.1093/brain/awh214 Chiaravalloti, N. D. & DeLuca, J. (2008). Cognitive impairment in multiple sclerosis. The Lancet Neurol, 7(12), 1139–1151. https://doi.org/10.1016/s1474-4422(08)70259-x Cotter J.; Firth, J.; Enzinger, C.; Kontopantelis, E.; Yung, A. R.; Elliott, R. & Drake, R. J. (2016). Social cognition in multiple sclerosis: A systematic review and meta-analysis. Neurology, 87(16), 1727–1736. https://doi.org/10.1212/wnl.0000000000003236 Di Bitonto, L.; Longato, N.; Jung, B.; Fleury, M.; Marcel, C.; Collongues, N.; de Seze, J. & Blanc, F. (2011). Reduced emotional reactivity to negative stimuli in multiple sclerosis, preliminary results. Revue Neurolique (Paris), 167(11), 820–826. https://doi.org/10.1016/j.neurol.2011.01.02477 Henry, J. D.; Phillips, L. H.; Beatty, W. W.; McDonald, S.; Longley, W. A.; Joscelyne, A. & Rendell, P. G. (2009). Evidence for deficits in facial affect recognition and theory of mind in multiple sclerosis. Journal of the International Neuropsychological Society, 15(2), 277–285. https://doi.org/10.1017/s1355617709090195 Jehna, M.; Langkammer, C.; Wallner-Blazek, M.; Neuper, Ch.; Loitfelder, M.; Ropele, S.; Fuchs, S.; Khalil, M.; Pluta-Fuerst, A.; Fazekas, F. & Enzinger, Ch. (2011). Cognitively preserved MS patients demonstrate functional differences in processing neutral and emotional faces. Brain Imaging and Behavior, 5(4), 241–251. https://doi.org/10.1007/s11682-011-9128-1 Kurtzke J. F. (1983). Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology, 33(11), 1444–1452. https://doi.org/10.1212/wnl.33.11.1444 Lang, P. J.; Bradley, M. M. & Cuthbert, B. N. (2008). International affective picture system (IAPS): Affective ratings of pictures and instruction manual. [Technical Report A-8]. Gainesville: University of Florida. Available from https://www2.unifesp.br/dpsicobio/adap/instructions.pdf Langdon, D. W. (2011). Cognition in Multiple Sclerosis. Current Opinion in Neurology, 24(3), 244–249. https://doi.org/10.1097/wco.0b013e328346a43b Louwerse, A.; Tulen, J. H.; van der Geest, J. N.; van der Ende, J. & Verhulst, F. C. (2014). Greaves-Lord K. Autonomic responses to social and nonsocial pictures in adolescents with autism spectrum disorder. Autism Research, 7(1), 17–27. https://doi.org/10.1002/aur.1327 Mao, C. V.; Araujo, M. F.; Nishimaru, H.; Matsumoto, J.; Tran, A. H.; Hori, E.; Ono, T. & Nishijo, H. (2017). Pregenual Anterior Cingulate Gyrus Involvement in Spontaneous Social Interactions in Primates-Evidence from Behavioral, Pharmacological, Neuropsychiatric, and Neurophysiological Findings. Frontiers in Neuroscience, 11, 1–10. https://dx.doi.org/10.3389%2Ffnins.2017.00034 McDonald, W. I.; Compston, A.; Edan, G.; Goodkin, D.; Hartung, H. P.; Lublin, F. D.; McFarland, H. F.; Paty, D. W.; Polman, C. H.; Reingold, S. C.; Sandberg-Wollheim, M.; Sibley, W.; Thompson, A.; Van den Noort, S.; Weinshenker, B. Y.; Wolinsky, J. S. (2001). Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis. Annals of Neurology, 50(1), 121–127. https://doi.org/10.1002/ana.1032 Ouellet, J.; Scherzer, P. B.; Rouleau, I.; Métras, P.; Bertrand-Gauvin, C.; Djerroud, N.; Boisseau E. & Duquette, P. (2010). Assessment of social cognition in patients with multiple sclerosis. Journal of the IntNeuropsychological Society, 16(2), 287–296. https://doi.org/10.1017/s1355617709991329 Román, F.; Rojas, Galeno; N. R., Iturry, M.; Blanco, R.; Leis, A.; Bartoloni, L. & Allegri , R. F. (2012). Baremos del Test de la Mirada en español en adultos normales de Buenos Aires. Revista Neuropsicología Latinoamericana, 4(3), 1–5. Disponible en https://www.neuropsicolatina.org/index.php/Neuropsicologia_Latinoamericana/article/view/108 Schulz, K. P.; Clerkin, S. M.; Halperin, J. M.; Newcorn, J. H.; Tang, C. Y. & Fan, J. (2009). Dissociable neural effects of stimulus valence and preceding context during the inhibition of responses to emotional faces. Hum Brain Mapp, 30(9), 2821–2833. https://doi.org/10.1002/hbm.20706 Sprengelmeyer, R.; Young, A. W., Calder, A. J., Karnat, A.; Lange, H.; Hömberg, V.; Perrett, D. I. & Rowland, D. (1996). Loss of disgust. Perception of faces and emotions in Huntington’s disease. Brain: a journal of Neulogy, 119( Pt 5), 1647–1665. https://doi.org/10.1093/brain/119.5.1647 Stone, V. E.; Baron-Cohen, S. & Knight, R. T. (1998). Frontal lobe contributions to theory of mind. Journal of Cognitive Neuroscience, 10(5), 640–656. https://doi.org/10.1162/089892998562942 |
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Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)Copyright (c) 2021 Journal of Applied Cognitive Neurosciencehttps://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Crivelli, LucíaCalandri, Ismael LuisHelou, BelénKeller, GretaFiol, Marcela Paula Ysraelit, María-CélicaGaitán, María-InésCorreale, Jorge2023-05-15T13:09:09Z2023-05-15T13:09:09Z2021-03-27Crivelli, L., Calandri, I.-L., Helou, B., Keller, G., Fiol, M.-P., Ysraelit, M.-C., Gaitan, M.-I., & Correale, J. (2021). Social Cognition In Early Multiple Sclerosis: Neuropsychological And Anatomical Approach: Cognición Social En La Esclerosis Múltiple Temprana: Enfoque Neuropsicológico Y Anatómico. Journal of Applied Cognitive Neuroscience, 2(1), e00153735. https://doi.org/10.17981/JACN.2.1.2021.03https://hdl.handle.net/11323/1013310.17981/JACN.2.1.2021.032745-0031Corporación Universidad de la CostaREDICUC – Repositorio CUChttps://repositorio.cuc.edu.co/Cognitive impairment and deficits in Social Cognition (SC) are frequent in patients with Multiple Sclerosis (MS). The aim of the present work is to study SC in patients with early MS and to analyze its neuroanatomical correlation. Thirty-four patients with relapsing remitting MS, with ≤ 2 years of disease progression and EDSS and ≤ 2, and 30 healthy control subjects matched for age, sex, and educational level were recruited. Subjects performed a comprehensive neuropsychological assessment (Rao BRB). SC was assessed using the International Affective Picture System IAPS, The Eyes in the Mind Test, the Empathy Quotient, and the Faux Pas Test. The anatomical correlation of patients with deficits in social cognition was studied through brain MRI and voxel-based morphometric for which cortical reconstruction and volumetric segmentation were performed using Freesurfer processing software. Patients showed significant deficits in executive functions, verbal memory and language tests. SC assessment showed that patients presented greater difficulties in the Faux Pas Test (p = 0.023), The Mind in the Eyes Test (p = 0.014), and presented a positive bias in the interpretation of neutral images of the IAPS (P = 0.023). Furthermore, patients with CS deficits presented less cortical thickness in areas of the right supramarginal gyrus, pars opercularis, and anterior cingulum.El deterioro cognitivo y los déficits en la cognición Social (CS) son frecuentes en pacientes con Esclerosis Múltiple (EM). El objetivo del presente trabajo es estudiar la CS en pacientes con EM temprana y analizar su correlación neuroanatómica. Se reclutaron 34 pacientes con EM remitente recidivante, con ≤ 2 años de progresión de la enfermedad y EDSS y ≤ 2, y 30 sujetos control sanos emparejados por edad, sexo y nivel educativo. Los sujetos realizaron una evaluación neuropsicológica completa (Rao BRB). La CS se evaluó mediante el Sistema Internacional de Imágenes Afectivas IAPS, el Test de la Mirada, el Cociente de Empatía y el Test de Faux Pas. La correlación anatómica de los pacientes con los déficits en cognición social se estudió mediante resonancia magnética cerebral y morfometría basada en vóxeles, para lo cual se realizó la reconstrucción cortical y la segmentación volumétrica mediante el software de procesamiento Freesurfer. Los pacientes mostraron déficits significativos en las funciones ejecutivas, la memoria verbal y las pruebas de lenguaje. La evaluación de la CS mostró que los pacientes presentaban mayores dificultades en el Faux Pas Test (p = 0.023), el Test de la Mirada (p = 0.014), y presentaban un sesgo positivo en la interpretación de imágenes neutras del IAPS (P = 0.023). Además, los pacientes con déficits de CS presentaron un menor grosor cortical en áreas del giro supramarginal derecho, la pars opercularis y el cíngulo anterior.14 páginasapplication/pdfengCorporación Universidad de la CostaColombiahttps://revistascientificas.cuc.edu.co/JACN/article/view/3735Social cognition in early multiple sclerosis: neuropsychological and anatomical approachLa cognición social en la esclerosis múltiple temprana: enfoque neuropsicológico y anatómicoArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85Journal of Applied Cognitive NeuroscienceApps, M. A.; Rushworth, M. F. & Chang, S. W. (2016). The Anterior Cingulate Gyrus and Social Cognition: Tracking the Motivation of Others. Neuron, 90(4), 692–707. https://doi.org/10.1016/j.neuron.2016.04.018Banati, M.; Sandor, J.; Mike A.; Illes, E.; Bors, L.; Feldmann, A.; Herold, R. & Illes, Z. (2010). Social cognition and Theory of Mind in patients with relapsing-remitting multiple sclerosis. Europena Journal of Neurology, 17(3), 426–433. https://doi.org/10.1111/j.1468-1331.2009.02836.xBaron-Cohen, S. & Wheelwright, S. (2004). The Empathy Quotient: An Investigation Of Adults With Asperger Syndrome Or High Functioning Autism, And NormalSex Differences, Journal of Autism and Developmental Disorders, 34(2), 163–175. https://doi.org/10.1023/b:jadd.0000022607.19833.00Batista, S.; D’Almeida, O. C.; Afonso, A.; Freitas, S.; Macário, C.; Sousa, L.; Castelo-Branco, M.; Santana, I. & Cunha, L. (2017). Impairment of social cognition in multiple sclerosis: Amygdala atrophy is the main predictor. Multiple Sclerosis Journal, 23(10), 1358–1366. https://doi.org/10.1177/1352458516680750Bradley, M. & Lang, P. (1994). Measuring emotion: The self-assessment manikin and the semantic differential. Journal of Behavior Therapy and Experimental Psychiatry, 25(1), 49–59. https://doi.org/10.1016/0005-7916(94)90063-9Cáceres, F.; Vanotti, S.; Rao, S. & RECONEM Workgroup. (2011). Epidemiological characteristics of cognitive impairment of multiple sclerosis patients in a Latin American country. Journal of Clinical and Experimental Neuropsychology, 33(10), 1094–1098. https://doi.org/10.1080/13803395.2011.603690Calder, A. J.; Keane, J.; Lawrence, A. D. & Manes F. (2004). Impaired recognition of anger following damage to the ventral striatum. Brain: a journal of Neulogy, 127(Pt 9), 1958–1969. https://doi.org/10.1093/brain/awh214Chiaravalloti, N. D. & DeLuca, J. (2008). Cognitive impairment in multiple sclerosis. The Lancet Neurol, 7(12), 1139–1151. https://doi.org/10.1016/s1474-4422(08)70259-xCotter J.; Firth, J.; Enzinger, C.; Kontopantelis, E.; Yung, A. R.; Elliott, R. & Drake, R. J. (2016). Social cognition in multiple sclerosis: A systematic review and meta-analysis. Neurology, 87(16), 1727–1736. https://doi.org/10.1212/wnl.0000000000003236Di Bitonto, L.; Longato, N.; Jung, B.; Fleury, M.; Marcel, C.; Collongues, N.; de Seze, J. & Blanc, F. (2011). Reduced emotional reactivity to negative stimuli in multiple sclerosis, preliminary results. Revue Neurolique (Paris), 167(11), 820–826. https://doi.org/10.1016/j.neurol.2011.01.02477Henry, J. D.; Phillips, L. H.; Beatty, W. W.; McDonald, S.; Longley, W. A.; Joscelyne, A. & Rendell, P. G. (2009). Evidence for deficits in facial affect recognition and theory of mind in multiple sclerosis. Journal of the International Neuropsychological Society, 15(2), 277–285. https://doi.org/10.1017/s1355617709090195Jehna, M.; Langkammer, C.; Wallner-Blazek, M.; Neuper, Ch.; Loitfelder, M.; Ropele, S.; Fuchs, S.; Khalil, M.; Pluta-Fuerst, A.; Fazekas, F. & Enzinger, Ch. (2011). 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Journal of Cognitive Neuroscience, 10(5), 640–656. https://doi.org/10.1162/08989299856294214112Cognitive dysfunctionSocial cognitionMultiple sclerosisNeuropsychological testDisease progressionDisfunción cognitivaCognición socialEsclerosis múltipleTest neuropsicológicoProgresión de la enfermedadPublicationORIGINALSocial Cognition In Early Multiple Sclerosis.pdfSocial Cognition In Early Multiple Sclerosis.pdfArtículoapplication/pdf932901https://repositorio.cuc.edu.co/bitstreams/f397ec53-ccba-4cb1-88dd-ac039ab78c8d/downloadad3fec7f031317ee1b06790dec928182MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-814828https://repositorio.cuc.edu.co/bitstreams/e37b7247-05e3-4a2b-a5a1-8c2138239ded/download2f9959eaf5b71fae44bbf9ec84150c7aMD52TEXTSocial Cognition In Early Multiple Sclerosis.pdf.txtSocial Cognition In Early Multiple Sclerosis.pdf.txtExtracted texttext/plain36295https://repositorio.cuc.edu.co/bitstreams/4d6662f2-768e-4959-ad2b-32eecd22a3c5/downloadf944622cffa88c51048681c77254345bMD53THUMBNAILSocial Cognition In Early Multiple Sclerosis.pdf.jpgSocial Cognition In Early Multiple Sclerosis.pdf.jpgGenerated Thumbnailimage/jpeg12687https://repositorio.cuc.edu.co/bitstreams/7cc8ceb0-712d-4b3c-84fd-51151365013b/downloadbe63e6edfc03d34b456a339b273d0782MD5411323/10133oai:repositorio.cuc.edu.co:11323/101332024-09-17 11:00:15.07https://creativecommons.org/licenses/by-nc-nd/4.0/Copyright (c) 2021 Journal of Applied Cognitive Neuroscienceopen.accesshttps://repositorio.cuc.edu.coRepositorio de la Universidad de la Costa 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ada en las Obras Colectivas.

b.	Distribuir copias o fonogramas de las Obras, exhibirlas públicamente, ejecutarlas públicamente y/o ponerlas a disposición pública, incluyéndolas como incorporadas en Obras Colectivas, según corresponda.

c.	Distribuir copias de las Obras Derivadas que se generen, exhibirlas públicamente, ejecutarlas públicamente y/o ponerlas a disposición pública.
Los derechos mencionados anteriormente pueden ser ejercidos en todos los medios y formatos, actualmente conocidos o que se inventen en el futuro. Los derechos antes mencionados incluyen el derecho a realizar dichas modificaciones en la medida que sean técnicamente necesarias para ejercer los derechos en otro medio o formatos, pero de otra manera usted no está autorizado para realizar obras derivadas. Todos los derechos no otorgados expresamente por el Licenciante quedan por este medio reservados, incluyendo pero sin limitarse a aquellos que se mencionan en las secciones 4(d) y 4(e).

4. Restricciones.
La licencia otorgada en la anterior Sección 3 está expresamente sujeta y limitada por las siguientes restricciones:

a.	Usted puede distribuir, exhibir públicamente, ejecutar públicamente, o poner a disposición pública la Obra sólo bajo las condiciones de esta Licencia, y Usted debe incluir una copia de esta licencia o del Identificador Universal de Recursos de la misma con cada copia de la Obra que distribuya, exhiba públicamente, ejecute públicamente o ponga a disposición pública. No es posible ofrecer o imponer ninguna condición sobre la Obra que altere o limite las condiciones de esta Licencia o el ejercicio de los derechos de los destinatarios otorgados en este documento. No es posible sublicenciar la Obra. Usted debe mantener intactos todos los avisos que hagan referencia a esta Licencia y a la cláusula de limitación de garantías. Usted no puede distribuir, exhibir públicamente, ejecutar públicamente, o poner a disposición pública la Obra con alguna medida tecnológica que controle el acceso o la utilización de ella de una forma que sea inconsistente con las condiciones de esta Licencia. Lo anterior se aplica a la Obra incorporada a una Obra Colectiva, pero esto no exige que la Obra Colectiva aparte de la obra misma quede sujeta a las condiciones de esta Licencia. Si Usted crea una Obra Colectiva, previo aviso de cualquier Licenciante debe, en la medida de lo posible, eliminar de la Obra Colectiva cualquier referencia a dicho Licenciante o al Autor Original, según lo solicitado por el Licenciante y conforme lo exige la cláusula 4(c).

b.	Usted no puede ejercer ninguno de los derechos que le han sido otorgados en la Sección 3 precedente de modo que estén principalmente destinados o directamente dirigidos a conseguir un provecho comercial o una compensación monetaria privada. El intercambio de la Obra por otras obras protegidas por derechos de autor, ya sea a través de un sistema para compartir archivos digitales (digital file-sharing) o de cualquier otra manera no será considerado como estar destinado principalmente o dirigido directamente a conseguir un provecho comercial o una compensación monetaria privada, siempre que no se realice un pago mediante una compensación monetaria en relación con el intercambio de obras protegidas por el derecho de autor.

c.	Si usted distribuye, exhibe públicamente, ejecuta públicamente o ejecuta públicamente en forma digital la Obra o cualquier Obra Derivada u Obra Colectiva, Usted debe mantener intacta toda la información de derecho de autor de la Obra y proporcionar, de forma razonable según el medio o manera que Usted esté utilizando: (i) el nombre del Autor Original si está provisto (o seudónimo, si fuere aplicable), y/o (ii) el nombre de la parte o las partes que el Autor Original y/o el Licenciante hubieren designado para la atribución (v.g., un instituto patrocinador, editorial, publicación) en la información de los derechos de autor del Licenciante, términos de servicios o de otras formas razonables; el título de la Obra si está provisto; en la medida de lo razonablemente factible y, si está provisto, el Identificador Uniforme de Recursos (Uniform Resource Identifier) que el Licenciante especifica para ser asociado con la Obra, salvo que tal URI no se refiera a la nota sobre los derechos de autor o a la información sobre el licenciamiento de la Obra; y en el caso de una Obra Derivada, atribuir el crédito identificando el uso de la Obra en la Obra Derivada (v.g., "Traducción Francesa de la Obra del Autor Original," o "Guión Cinematográfico basado en la Obra original del Autor Original"). Tal crédito puede ser implementado de cualquier forma razonable; en el caso, sin embargo, de Obras Derivadas u Obras Colectivas, tal crédito aparecerá, como mínimo, donde aparece el crédito de cualquier otro autor comparable y de una manera, al menos, tan destacada como el crédito de otro autor comparable.

d.	Para evitar toda confusión, el Licenciante aclara que, cuando la obra es una composición musical:

i.	Regalías por interpretación y ejecución bajo licencias generales. El Licenciante se reserva el derecho exclusivo de autorizar la ejecución pública o la ejecución pública digital de la obra y de recolectar, sea individualmente o a través de una sociedad de gestión colectiva de derechos de autor y derechos conexos (por ejemplo, SAYCO), las regalías por la ejecución pública o por la ejecución pública digital de la obra (por ejemplo Webcast) licenciada bajo licencias generales, si la interpretación o ejecución de la obra está primordialmente orientada por o dirigida a la obtención de una ventaja comercial o una compensación monetaria privada.

ii.	Regalías por Fonogramas. El Licenciante se reserva el derecho exclusivo de recolectar, individualmente o a través de una sociedad de gestión colectiva de derechos de autor y derechos conexos (por ejemplo, los consagrados por la SAYCO), una agencia de derechos musicales o algún agente designado, las regalías por cualquier fonograma que Usted cree a partir de la obra (“versión cover”) y distribuya, en los términos del régimen de derechos de autor, si la creación o distribución de esa versión cover está primordialmente destinada o dirigida a obtener una ventaja comercial o una compensación monetaria privada.

e.	Gestión de Derechos de Autor sobre Interpretaciones y Ejecuciones Digitales (WebCasting). Para evitar toda confusión, el Licenciante aclara que, cuando la obra sea un fonograma, el Licenciante se reserva el derecho exclusivo de autorizar la ejecución pública digital de la obra (por ejemplo, webcast) y de recolectar, individualmente o a través de una sociedad de gestión colectiva de derechos de autor y derechos conexos (por ejemplo, ACINPRO), las regalías por la ejecución pública digital de la obra (por ejemplo, webcast), sujeta a las disposiciones aplicables del régimen de Derecho de Autor, si esta ejecución pública digital está primordialmente dirigida a obtener una ventaja comercial o una compensación monetaria privada.

5. Representaciones, Garantías y Limitaciones de Responsabilidad.
A MENOS QUE LAS PARTES LO ACORDARAN DE OTRA FORMA POR ESCRITO, EL LICENCIANTE OFRECE LA OBRA (EN EL ESTADO EN EL QUE SE ENCUENTRA) “TAL CUAL”, SIN BRINDAR GARANTÍAS DE CLASE ALGUNA RESPECTO DE LA OBRA, YA SEA EXPRESA, IMPLÍCITA, LEGAL O CUALQUIERA OTRA, INCLUYENDO, SIN LIMITARSE A ELLAS, GARANTÍAS DE TITULARIDAD, COMERCIABILIDAD, ADAPTABILIDAD O ADECUACIÓN A PROPÓSITO DETERMINADO, AUSENCIA DE INFRACCIÓN, DE AUSENCIA DE DEFECTOS LATENTES O DE OTRO TIPO, O LA PRESENCIA O AUSENCIA DE ERRORES, SEAN O NO DESCUBRIBLES (PUEDAN O NO SER ESTOS DESCUBIERTOS). ALGUNAS JURISDICCIONES NO PERMITEN LA EXCLUSIÓN DE GARANTÍAS IMPLÍCITAS, EN CUYO CASO ESTA EXCLUSIÓN PUEDE NO APLICARSE A USTED.

6. Limitación de responsabilidad.
A MENOS QUE LO EXIJA EXPRESAMENTE LA LEY APLICABLE, EL LICENCIANTE NO SERÁ RESPONSABLE ANTE USTED POR DAÑO ALGUNO, SEA POR RESPONSABILIDAD EXTRACONTRACTUAL, PRECONTRACTUAL O CONTRACTUAL, OBJETIVA O SUBJETIVA, SE TRATE DE DAÑOS MORALES O PATRIMONIALES, DIRECTOS O INDIRECTOS, PREVISTOS O IMPREVISTOS PRODUCIDOS POR EL USO DE ESTA LICENCIA O DE LA OBRA, AUN CUANDO EL LICENCIANTE HAYA SIDO ADVERTIDO DE LA POSIBILIDAD DE DICHOS DAÑOS. ALGUNAS LEYES NO PERMITEN LA EXCLUSIÓN DE CIERTA RESPONSABILIDAD, EN CUYO CASO ESTA EXCLUSIÓN PUEDE NO APLICARSE A USTED.

7. Término.

a.	Esta Licencia y los derechos otorgados en virtud de ella terminarán automáticamente si Usted infringe alguna condición establecida en ella. Sin embargo, los individuos o entidades que han recibido Obras Derivadas o Colectivas de Usted de conformidad con esta Licencia, no verán terminadas sus licencias, siempre que estos individuos o entidades sigan cumpliendo íntegramente las condiciones de estas licencias. Las Secciones 1, 2, 5, 6, 7, y 8 subsistirán a cualquier terminación de esta Licencia.

b.	Sujeta a las condiciones y términos anteriores, la licencia otorgada aquí es perpetua (durante el período de vigencia de los derechos de autor de la obra). No obstante lo anterior, el Licenciante se reserva el derecho a publicar y/o estrenar la Obra bajo condiciones de licencia diferentes o a dejar de distribuirla en los términos de esta Licencia en cualquier momento; en el entendido, sin embargo, que esa elección no servirá para revocar esta licencia o que deba ser otorgada , bajo los términos de esta licencia), y esta licencia continuará en pleno vigor y efecto a menos que sea terminada como se expresa atrás. La Licencia revocada continuará siendo plenamente vigente y efectiva si no se le da término en las condiciones indicadas anteriormente.

8. Varios.

a.	Cada vez que Usted distribuya o ponga a disposición pública la Obra o una Obra Colectiva, el Licenciante ofrecerá al destinatario una licencia en los mismos términos y condiciones que la licencia otorgada a Usted bajo esta Licencia.

b.	Si alguna disposición de esta Licencia resulta invalidada o no exigible, según la legislación vigente, esto no afectará ni la validez ni la aplicabilidad del resto de condiciones de esta Licencia y, sin acción adicional por parte de los sujetos de este acuerdo, aquélla se entenderá reformada lo mínimo necesario para hacer que dicha disposición sea válida y exigible.

c.	Ningún término o disposición de esta Licencia se estimará renunciada y ninguna violación de ella será consentida a menos que esa renuncia o consentimiento sea otorgado por escrito y firmado por la parte que renuncie o consienta.

d.	Esta Licencia refleja el acuerdo pleno entre las partes respecto a la Obra aquí licenciada. No hay arreglos, acuerdos o declaraciones respecto a la Obra que no estén especificados en este documento. El Licenciante no se verá limitado por ninguna disposición adicional que pueda surgir en alguna comunicación emanada de Usted. Esta Licencia no puede ser modificada sin el consentimiento mutuo por escrito del Licenciante y Usted.
 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