Direct medical costs and healthcare resource utilization of treating patients with two clinical subtypes of axial spondyloarthritis in Colombia
Objectives: This study aimed to calculate the healthcare resource utilization and direct medical costs in patients with 2 subtypes of axial spondyloarthritis (axSpA) in a rheumatic care center in Colombia. Methods: This is a retrospective cost-of-illness study. Patients with at least 1 medical consu...
- Autores:
-
Santos-Moreno, Pedro
Parra Padilla, Devian
Gómez-De la Rosa, Fernando
Carrasquilla-Sotomayor, María
Villarreal, Laura
Jervis-Jálabe, David Scott
ALVIS-ZAKZUK, NELSON J.
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2022
- Institución:
- Corporación Universidad de la Costa
- Repositorio:
- REDICUC - Repositorio CUC
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.cuc.edu.co:11323/10763
- Acceso en línea:
- https://hdl.handle.net/11323/10763
https://repositorio.cuc.edu.co/
- Palabra clave:
- Axial spondyloarthritis
Cost-of-illness
Economic burden
Healthcare resource utilization
- Rights
- embargoedAccess
- License
- Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)
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Direct medical costs and healthcare resource utilization of treating patients with two clinical subtypes of axial spondyloarthritis in Colombia |
| title |
Direct medical costs and healthcare resource utilization of treating patients with two clinical subtypes of axial spondyloarthritis in Colombia |
| spellingShingle |
Direct medical costs and healthcare resource utilization of treating patients with two clinical subtypes of axial spondyloarthritis in Colombia Axial spondyloarthritis Cost-of-illness Economic burden Healthcare resource utilization |
| title_short |
Direct medical costs and healthcare resource utilization of treating patients with two clinical subtypes of axial spondyloarthritis in Colombia |
| title_full |
Direct medical costs and healthcare resource utilization of treating patients with two clinical subtypes of axial spondyloarthritis in Colombia |
| title_fullStr |
Direct medical costs and healthcare resource utilization of treating patients with two clinical subtypes of axial spondyloarthritis in Colombia |
| title_full_unstemmed |
Direct medical costs and healthcare resource utilization of treating patients with two clinical subtypes of axial spondyloarthritis in Colombia |
| title_sort |
Direct medical costs and healthcare resource utilization of treating patients with two clinical subtypes of axial spondyloarthritis in Colombia |
| dc.creator.fl_str_mv |
Santos-Moreno, Pedro Parra Padilla, Devian Gómez-De la Rosa, Fernando Carrasquilla-Sotomayor, María Villarreal, Laura Jervis-Jálabe, David Scott ALVIS-ZAKZUK, NELSON J. |
| dc.contributor.author.none.fl_str_mv |
Santos-Moreno, Pedro Parra Padilla, Devian Gómez-De la Rosa, Fernando Carrasquilla-Sotomayor, María Villarreal, Laura Jervis-Jálabe, David Scott ALVIS-ZAKZUK, NELSON J. |
| dc.subject.proposal.eng.fl_str_mv |
Axial spondyloarthritis Cost-of-illness Economic burden Healthcare resource utilization |
| topic |
Axial spondyloarthritis Cost-of-illness Economic burden Healthcare resource utilization |
| description |
Objectives: This study aimed to calculate the healthcare resource utilization and direct medical costs in patients with 2 subtypes of axial spondyloarthritis (axSpA) in a rheumatic care center in Colombia. Methods: This is a retrospective cost-of-illness study. Patients with at least 1 medical consultation associated with an axSpA diagnosis between October 2018 and October 2019 were identified. Patients were classified as having radiographic (r-axSpA) or nonradiographic axSpA (nr-axSpA). Direct medical costs were calculated in Colombian pesos and expressed in American dollars using an exchange rate of 3263 Colombian pesos = 1 US dollar ($). Predictors of total direct costs were identified using a generalized linear model with gamma distribution and log-link. Results: A total of 162 patients with a mean age of 49.6 years (6 13.7) were included in the study. Among these, 147 (90.7%) were considered as having r-axSpA and 15 (9.3%) nr-axSpA, with mean costs of $6600 (6 6203) and $843 (6 1135), respectively (P , .001). The total direct mean cost was calculated at $6067 (6 6144) per patient. Medication costs were the main driver of total costs (97.6%, $5921), with biologic disease-modifying antirheumatic drugs accounting for nearly 92.0% ($5582) of these costs. Rheumatologist (100%) and physiatrist (64.2%) visits were the most frequently used medical service. Conclusions: The economic burden associated with axSpA in the Colombian setting is substantial. There is a significant difference in direct medical costs between the r-axSpA and the nr-axSpA. Health policies aimed at the comprehensive management of nr-axSpA would have an important role in the reduction of the associated direct medical costs. |
| publishDate |
2022 |
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2022 |
| dc.date.available.none.fl_str_mv |
2023 2024-02-21T22:29:15Z |
| dc.date.accessioned.none.fl_str_mv |
2024-02-21T22:29:15Z |
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Artículo de revista |
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info:eu-repo/semantics/article |
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http://purl.org/redcol/resource_type/ART |
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Pedro Santos-Moreno, Devian Parra-Padilla, Fernando Gómez-De la Rosa, María Carrasquilla-Sotomayor, Laura Villarreal, David Scott Jervis-Jálabe, Nelson J. Alvis-Zakzuk, Direct Medical Costs and Healthcare Resource Utilization of Treating Patients With Two Clinical Subtypes of Axial Spondyloarthritis in Colombia, Value in Health Regional Issues, Volume 32, 2022, Pages 88-94, ISSN 2212-1099, https://doi.org/10.1016/j.vhri.2022.08.003 |
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2212-1099 |
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https://hdl.handle.net/11323/10763 |
| dc.identifier.doi.none.fl_str_mv |
10.1016/j.vhri.2022.08.003 |
| dc.identifier.eissn.spa.fl_str_mv |
2212-1102 |
| dc.identifier.instname.spa.fl_str_mv |
Corporación Universidad de la Costa |
| dc.identifier.reponame.spa.fl_str_mv |
REDICUC – Repositorio CUC |
| dc.identifier.repourl.spa.fl_str_mv |
https://repositorio.cuc.edu.co/ |
| identifier_str_mv |
Pedro Santos-Moreno, Devian Parra-Padilla, Fernando Gómez-De la Rosa, María Carrasquilla-Sotomayor, Laura Villarreal, David Scott Jervis-Jálabe, Nelson J. Alvis-Zakzuk, Direct Medical Costs and Healthcare Resource Utilization of Treating Patients With Two Clinical Subtypes of Axial Spondyloarthritis in Colombia, Value in Health Regional Issues, Volume 32, 2022, Pages 88-94, ISSN 2212-1099, https://doi.org/10.1016/j.vhri.2022.08.003 2212-1099 10.1016/j.vhri.2022.08.003 2212-1102 Corporación Universidad de la Costa REDICUC – Repositorio CUC |
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https://hdl.handle.net/11323/10763 https://repositorio.cuc.edu.co/ |
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eng |
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eng |
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Value in Health Regional Issues |
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1. Sebbag E, Felten R, Sagez F, Sibilia J, Devilliers H, Arnaud L. The world-wide burden of musculoskeletal diseases: a systematic analysis of the World Health Organization Burden of Diseases Database. Ann Rheum Dis. 2019;78(6):844–848. 2. Cross M, Smith E, Hoy D, et al. The global burden of rheumatoid arthritis: estimates from the Global Burden of Disease 2010 study. Ann Rheum Dis. 2014;73(7):1316–1322. 3. GBD 2017 Disease and Injury Incidence and Prevalence Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017 [published correction appears in Lancet. 2019;393(10190):e44]. Lancet. 2018;392(10159):1789–1858. 4. Sieper J, Poddubnyy D. Axial spondyloarthritis. Lancet. 2017;390(10089): 73–84. 5. Strand V, Singh JA. Patient burden of axial spondyloarthritis. J Clin Rheumatol. 2017;23(7):383–391. 6. Rohde G, Hansen BK, Prøven A, Haugeberg G. The relationship between demographic- and disease-related variables and health-related quality of life in patients with axial spondyloarthritis. BMC Musculoskelet Disord. 2017;18(1):328. 7. López-Medina C, Ramiro S, van der Heijde D, Sieper J, Dougados M, Molto A. Characteristics and burden of disease in patients with radiographic and nonradiographic axial spondyloarthritis: a comparison by systematic literature review and meta-analysis. RMD Open. 2019;5(2):e001108. 8. Kwan YH, Kwoh SY, Phang JK, et al. The direct and indirect costs of axial spondyloarthritis (axSpA) in Singapore. Int J Rheum Dis. 2020;23(3): 334–341. 9. MachadoMAdÁ, Ferre F, deMoura CS, et al. Costs of drug therapyin patientswith ankylosing spondylitis in Brazil. Rheumatol Ther. 2016;3(2):353–361. 10. Boonen A, van der Heijde D, Landewé R, et al. Direct costs of ankylosing spondylitis and its determinants: an analysis among three European countries. Ann Rheum Dis. 2003;62(8):732–740. 11. Akkoç N, Direskeneli H, Erdem H, et al. Direct and indirect costs associated with ankylosing spondylitis and related disease activity scores in Turkey. Rheumatol Int. 2015;35(9):1473–1478. 12. Krüger K, von Hinüber U, Meier F, et al. Ankylosing spondylitis causes high burden to patients and the healthcare system: results from a German claims database analysis. Rheumatol Int. 2018;38(11):2121–2131. 13. Reveille JD, Ximenes A, Ward MM. Economic considerations of the treatment of ankylosing spondylitis. Am J Med Sci. 2012;343(5):371–374. 14. Malaviya A. Classification of spondyloarthritis: a journey well worth. Indian J Rheumatol. 2013;8(3):122–129. 15. Yi E, Ahuja A, Rajput T, George AT, Park Y. Clinical, economic, and humanistic burden associated with delayed diagnosis of axial spondyloarthritis: a systematic review. Rheumatol Ther. 2020;7(1):65–87. 16. Rocha FAC. Latin-American challenges and opportunities in rheumatology. Arthritis Res Ther. 2017;19(1):29. 17. Brenol CV, Ivan J, Nava G, Soriano ER. Proper management of rheumatoid arthritis in Latin America. What the guidelines say? [published correction appears in Clin Rheumatol. 2015;34(suppl 1):S57]. Clin Rheumatol. 2015;34(suppl 1):S51–S55. 18. Colombia - Régimen subsidiado del sistema general de seguridad social en salud de Colombia - Serie de estudios ÚNICO. Banco Mundial. https:// openknowledge.worldbank.org/handle/10986/13285. Accessed June 5, 2022. 19. Guerrero MC R, Gallego AI, Becerril-Montekio V, et al. Sistema de salud de Colombia. Salud Publ Mex. 2011;53(suppl 2):S144–S155. 20. Acceso a servicios de salud en Colombia. Décimo primer Informe Técnico Bogotá. Instituto Nacional de Salud. Observatorio Nacional de Salud. https:// www.ins.gov.co/Direcciones/ONS/Resumenes%20Ejecutivos/Resumen%20ej ecutivo%20informe%2011%20acceso%20a%20servicios%20en%20salud%20en %20Colombia.pdf. Accessed June 5, 2022. 21. Comportamiento del aseguramiento. Ministerio de Salud y Protección Social. https://www.minsalud.gov.co/proteccionsocial/Regimensubsidiado/Paginas/ coberturas-del-regimen-subsidiado.aspx. Accessed May 21, 2020. 22. Lindström U, Bremander A, Bergman S, Haglund E, Petersson IF, Jacobsson LT. SAT0253 patients with non-as axial SPA have similar prevalence compared to as, but worse perceived health. Results from a population based study. Ann Rheum Dis. 2013;72(suppl 3):A667-A668. https://ard.bmj.com/content/72/ Suppl_3/A667.3. Accessed June 5, 2022. 23. Jovani V, Loza E, García de Yébenes MJ, et al. Variability in resource consumption in patients with spondyloarthritis in Spain. Preliminary descriptive data from the emAR II study. ReumatolClin. 2012;8:114–119. 24. SISMED, Sistema de Información de Precios de Medicamentos. Ministerio de Salud y Protección Social. https://www.sispro.gov.co/central-prestadores-deservicios/Pages/SISMED-Sistema-de-Informacion-de-Precios-de-Medicamentos. aspx. Accessed June 5, 2022. 25. Manual para la elaboración de evaluaciones económicas en salud. Instituto de Evaluación Tecnológica en Salud-IETS. http://www.iets.org.co/ Archivos/64/Manual_evaluacion_economica.pdf. Accessed June 5, 2022. 26. Santos-Moreno P, Gómez-De la Rosa F, Parra-Padilla D, et al. Frequency of health care resource utilization and direct medical costs associated with psoriatic arthritisin a Rheumatic Care Centerin Colombia. Psoriasis (Auckl). 2021;11:31–39. 27. Acuerdo No. 256 de 2001 - manual de tarifas de la entidad promotora de salud del seguro social. Ministerio de Salud y Protección Social. https:// lexsaludcolombia.files.wordpress.com/2010/10/tarifas-iss-2001.pdf. Accessed June 6, 2022. 28. Tasa representativa del mercado (TRM - Peso por dólar). Banco de la República, Colombia. https://www.banrep.gov.co/es/estadisticas/trm. Accessed February 12, 2021. 29. Ramsey SD, Willke RJ, Glick H, et al. Cost-effectiveness analysis alongside clinical trials II—an ISPOR good research practices task force report. Value Health. 2015;18(2):161–172. 30. Mihaylova B, Briggs A, O’Hagan A, Thompson SG. Review of statistical methods for analysing healthcare resources and costs. Health Econ. 2011;20(8):897–916. 31. Barber J, Thompson S. Multiple regression of cost data: use of generalised linear models. J Health Serv Res Policy. 2004;9(4):197–204. 32. Azevedo VF, Rossetto CN, Lorencetti PG, Tramontin MY, Fornazari B, Araújo DV. Indirect and direct costs of treating patients with ankylosing spondylitis in the Brazilian public health system. Rev Bras Reumatol Engl Ed. 2016;56(2):131–137. 33. Fitzgerald GE, Maguire S, Lopez-Medina C, Dougados M, O’Shea FD, Haroon N. Tender to touch - prevalence and impact of concomitant fibromyalgia and enthesitis in spondyloarthritis: an ancillary analysis of the ASAS PerSpA study. Joint Bone Spine. 2022;89(6):105420. 34. Zhao SS, Robertson S, Reich T, Harrison NL, Moots RJ, Goodson NJ. Prevalence and impact of comorbidities in axial spondyloarthritis: systematic review and meta-analysis. Rheumatology (Oxford). 2020;59(suppl 4):iv47–iv57. 35. Puche-Larrubia MÁ, Ladehesa-Pineda L, Font-Ugalde P, et al. Distribution of comorbidities in spondyloarthritis with regard to the phenotype and psoriasis: data from the ASAS-COMOSPA study. Ther Adv Musculoskelet Dis. 2021;13:1759720X211045263. 36. Westhovens R, Annemans L. Costs of drugs for treatment of rheumatic diseases. RMD Open. 2016;2(2):e000259. |
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ª 2022 International Society for Health Economics and Outcomes Research. Published by Elsevier Inc |
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Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0) |
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Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)ª 2022 International Society for Health Economics and Outcomes Research. Published by Elsevier Inchttps://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/embargoedAccesshttp://purl.org/coar/access_right/c_f1cfSantos-Moreno, Pedro3ed99bf75e8c26aaf5968cb25da0141d600Parra Padilla, Devian1cd82259818901e72117a6c61da72b0f600Gómez-De la Rosa, Fernando88cc29abeabf182a6b474770a8df5468Carrasquilla-Sotomayor, María1730673880ce48e776774aa7c088e6ffVillarreal, Laurac08a32f86cf59a5be1490c08195ab35bJervis-Jálabe, David Scottf680c8fc23a1075c5bc9c77f3a03310dALVIS-ZAKZUK, NELSON J.00644ca08291213271c11d23d82b8cb56002024-02-21T22:29:15Z20232024-02-21T22:29:15Z2022Pedro Santos-Moreno, Devian Parra-Padilla, Fernando Gómez-De la Rosa, María Carrasquilla-Sotomayor, Laura Villarreal, David Scott Jervis-Jálabe, Nelson J. Alvis-Zakzuk, Direct Medical Costs and Healthcare Resource Utilization of Treating Patients With Two Clinical Subtypes of Axial Spondyloarthritis in Colombia, Value in Health Regional Issues, Volume 32, 2022, Pages 88-94, ISSN 2212-1099, https://doi.org/10.1016/j.vhri.2022.08.0032212-1099https://hdl.handle.net/11323/1076310.1016/j.vhri.2022.08.0032212-1102Corporación Universidad de la CostaREDICUC – Repositorio CUChttps://repositorio.cuc.edu.co/Objectives: This study aimed to calculate the healthcare resource utilization and direct medical costs in patients with 2 subtypes of axial spondyloarthritis (axSpA) in a rheumatic care center in Colombia. Methods: This is a retrospective cost-of-illness study. Patients with at least 1 medical consultation associated with an axSpA diagnosis between October 2018 and October 2019 were identified. Patients were classified as having radiographic (r-axSpA) or nonradiographic axSpA (nr-axSpA). Direct medical costs were calculated in Colombian pesos and expressed in American dollars using an exchange rate of 3263 Colombian pesos = 1 US dollar ($). Predictors of total direct costs were identified using a generalized linear model with gamma distribution and log-link. Results: A total of 162 patients with a mean age of 49.6 years (6 13.7) were included in the study. Among these, 147 (90.7%) were considered as having r-axSpA and 15 (9.3%) nr-axSpA, with mean costs of $6600 (6 6203) and $843 (6 1135), respectively (P , .001). The total direct mean cost was calculated at $6067 (6 6144) per patient. Medication costs were the main driver of total costs (97.6%, $5921), with biologic disease-modifying antirheumatic drugs accounting for nearly 92.0% ($5582) of these costs. Rheumatologist (100%) and physiatrist (64.2%) visits were the most frequently used medical service. Conclusions: The economic burden associated with axSpA in the Colombian setting is substantial. There is a significant difference in direct medical costs between the r-axSpA and the nr-axSpA. Health policies aimed at the comprehensive management of nr-axSpA would have an important role in the reduction of the associated direct medical costs.7 páginasapplication/pdfengElsevier USAUnited Stateshttps://www.sciencedirect.com/science/article/pii/S2212109922001455?via%3DihubDirect medical costs and healthcare resource utilization of treating patients with two clinical subtypes of axial spondyloarthritis in ColombiaArtículo de revistahttp://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85Value in Health Regional Issues1. Sebbag E, Felten R, Sagez F, Sibilia J, Devilliers H, Arnaud L. The world-wide burden of musculoskeletal diseases: a systematic analysis of the World Health Organization Burden of Diseases Database. Ann Rheum Dis. 2019;78(6):844–848.2. Cross M, Smith E, Hoy D, et al. The global burden of rheumatoid arthritis: estimates from the Global Burden of Disease 2010 study. Ann Rheum Dis. 2014;73(7):1316–1322.3. GBD 2017 Disease and Injury Incidence and Prevalence Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017 [published correction appears in Lancet. 2019;393(10190):e44]. Lancet. 2018;392(10159):1789–1858.4. Sieper J, Poddubnyy D. Axial spondyloarthritis. Lancet. 2017;390(10089): 73–84.5. Strand V, Singh JA. Patient burden of axial spondyloarthritis. J Clin Rheumatol. 2017;23(7):383–391.6. Rohde G, Hansen BK, Prøven A, Haugeberg G. The relationship between demographic- and disease-related variables and health-related quality of life in patients with axial spondyloarthritis. BMC Musculoskelet Disord. 2017;18(1):328.7. López-Medina C, Ramiro S, van der Heijde D, Sieper J, Dougados M, Molto A. Characteristics and burden of disease in patients with radiographic and nonradiographic axial spondyloarthritis: a comparison by systematic literature review and meta-analysis. RMD Open. 2019;5(2):e001108.8. Kwan YH, Kwoh SY, Phang JK, et al. The direct and indirect costs of axial spondyloarthritis (axSpA) in Singapore. Int J Rheum Dis. 2020;23(3): 334–341.9. MachadoMAdÁ, Ferre F, deMoura CS, et al. Costs of drug therapyin patientswith ankylosing spondylitis in Brazil. Rheumatol Ther. 2016;3(2):353–361.10. Boonen A, van der Heijde D, Landewé R, et al. Direct costs of ankylosing spondylitis and its determinants: an analysis among three European countries. Ann Rheum Dis. 2003;62(8):732–740.11. Akkoç N, Direskeneli H, Erdem H, et al. Direct and indirect costs associated with ankylosing spondylitis and related disease activity scores in Turkey. Rheumatol Int. 2015;35(9):1473–1478.12. Krüger K, von Hinüber U, Meier F, et al. Ankylosing spondylitis causes high burden to patients and the healthcare system: results from a German claims database analysis. Rheumatol Int. 2018;38(11):2121–2131.13. Reveille JD, Ximenes A, Ward MM. Economic considerations of the treatment of ankylosing spondylitis. Am J Med Sci. 2012;343(5):371–374.14. Malaviya A. Classification of spondyloarthritis: a journey well worth. Indian J Rheumatol. 2013;8(3):122–129.15. Yi E, Ahuja A, Rajput T, George AT, Park Y. Clinical, economic, and humanistic burden associated with delayed diagnosis of axial spondyloarthritis: a systematic review. Rheumatol Ther. 2020;7(1):65–87.16. Rocha FAC. Latin-American challenges and opportunities in rheumatology. Arthritis Res Ther. 2017;19(1):29.17. Brenol CV, Ivan J, Nava G, Soriano ER. Proper management of rheumatoid arthritis in Latin America. What the guidelines say? [published correction appears in Clin Rheumatol. 2015;34(suppl 1):S57]. Clin Rheumatol. 2015;34(suppl 1):S51–S55.18. Colombia - Régimen subsidiado del sistema general de seguridad social en salud de Colombia - Serie de estudios ÚNICO. Banco Mundial. https:// openknowledge.worldbank.org/handle/10986/13285. Accessed June 5, 2022.19. Guerrero MC R, Gallego AI, Becerril-Montekio V, et al. Sistema de salud de Colombia. Salud Publ Mex. 2011;53(suppl 2):S144–S155.20. Acceso a servicios de salud en Colombia. Décimo primer Informe Técnico Bogotá. Instituto Nacional de Salud. Observatorio Nacional de Salud. https:// www.ins.gov.co/Direcciones/ONS/Resumenes%20Ejecutivos/Resumen%20ej ecutivo%20informe%2011%20acceso%20a%20servicios%20en%20salud%20en %20Colombia.pdf. Accessed June 5, 2022.21. Comportamiento del aseguramiento. Ministerio de Salud y Protección Social. https://www.minsalud.gov.co/proteccionsocial/Regimensubsidiado/Paginas/ coberturas-del-regimen-subsidiado.aspx. 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corporada en las Obras Colectivas.

b.	Distribuir copias o fonogramas de las Obras, exhibirlas públicamente, ejecutarlas públicamente y/o ponerlas a disposición pública, incluyéndolas como incorporadas en Obras Colectivas, según corresponda.

c.	Distribuir copias de las Obras Derivadas que se generen, exhibirlas públicamente, ejecutarlas públicamente y/o ponerlas a disposición pública.
Los derechos mencionados anteriormente pueden ser ejercidos en todos los medios y formatos, actualmente conocidos o que se inventen en el futuro. Los derechos antes mencionados incluyen el derecho a realizar dichas modificaciones en la medida que sean técnicamente necesarias para ejercer los derechos en otro medio o formatos, pero de otra manera usted no está autorizado para realizar obras derivadas. Todos los derechos no otorgados expresamente por el Licenciante quedan por este medio reservados, incluyendo pero sin limitarse a aquellos que se mencionan en las secciones 4(d) y 4(e).

4. Restricciones.
La licencia otorgada en la anterior Sección 3 está expresamente sujeta y limitada por las siguientes restricciones:

a.	Usted puede distribuir, exhibir públicamente, ejecutar públicamente, o poner a disposición pública la Obra sólo bajo las condiciones de esta Licencia, y Usted debe incluir una copia de esta licencia o del Identificador Universal de Recursos de la misma con cada copia de la Obra que distribuya, exhiba públicamente, ejecute públicamente o ponga a disposición pública. No es posible ofrecer o imponer ninguna condición sobre la Obra que altere o limite las condiciones de esta Licencia o el ejercicio de los derechos de los destinatarios otorgados en este documento. No es posible sublicenciar la Obra. Usted debe mantener intactos todos los avisos que hagan referencia a esta Licencia y a la cláusula de limitación de garantías. Usted no puede distribuir, exhibir públicamente, ejecutar públicamente, o poner a disposición pública la Obra con alguna medida tecnológica que controle el acceso o la utilización de ella de una forma que sea inconsistente con las condiciones de esta Licencia. Lo anterior se aplica a la Obra incorporada a una Obra Colectiva, pero esto no exige que la Obra Colectiva aparte de la obra misma quede sujeta a las condiciones de esta Licencia. Si Usted crea una Obra Colectiva, previo aviso de cualquier Licenciante debe, en la medida de lo posible, eliminar de la Obra Colectiva cualquier referencia a dicho Licenciante o al Autor Original, según lo solicitado por el Licenciante y conforme lo exige la cláusula 4(c).

b.	Usted no puede ejercer ninguno de los derechos que le han sido otorgados en la Sección 3 precedente de modo que estén principalmente destinados o directamente dirigidos a conseguir un provecho comercial o una compensación monetaria privada. El intercambio de la Obra por otras obras protegidas por derechos de autor, ya sea a través de un sistema para compartir archivos digitales (digital file-sharing) o de cualquier otra manera no será considerado como estar destinado principalmente o dirigido directamente a conseguir un provecho comercial o una compensación monetaria privada, siempre que no se realice un pago mediante una compensación monetaria en relación con el intercambio de obras protegidas por el derecho de autor.

c.	Si usted distribuye, exhibe públicamente, ejecuta públicamente o ejecuta públicamente en forma digital la Obra o cualquier Obra Derivada u Obra Colectiva, Usted debe mantener intacta toda la información de derecho de autor de la Obra y proporcionar, de forma razonable según el medio o manera que Usted esté utilizando: (i) el nombre del Autor Original si está provisto (o seudónimo, si fuere aplicable), y/o (ii) el nombre de la parte o las partes que el Autor Original y/o el Licenciante hubieren designado para la atribución (v.g., un instituto patrocinador, editorial, publicación) en la información de los derechos de autor del Licenciante, términos de servicios o de otras formas razonables; el título de la Obra si está provisto; en la medida de lo razonablemente factible y, si está provisto, el Identificador Uniforme de Recursos (Uniform Resource Identifier) que el Licenciante especifica para ser asociado con la Obra, salvo que tal URI no se refiera a la nota sobre los derechos de autor o a la información sobre el licenciamiento de la Obra; y en el caso de una Obra Derivada, atribuir el crédito identificando el uso de la Obra en la Obra Derivada (v.g., "Traducción Francesa de la Obra del Autor Original," o "Guión Cinematográfico basado en la Obra original del Autor Original"). Tal crédito puede ser implementado de cualquier forma razonable; en el caso, sin embargo, de Obras Derivadas u Obras Colectivas, tal crédito aparecerá, como mínimo, donde aparece el crédito de cualquier otro autor comparable y de una manera, al menos, tan destacada como el crédito de otro autor comparable.

d.	Para evitar toda confusión, el Licenciante aclara que, cuando la obra es una composición musical:

i.	Regalías por interpretación y ejecución bajo licencias generales. El Licenciante se reserva el derecho exclusivo de autorizar la ejecución pública o la ejecución pública digital de la obra y de recolectar, sea individualmente o a través de una sociedad de gestión colectiva de derechos de autor y derechos conexos (por ejemplo, SAYCO), las regalías por la ejecución pública o por la ejecución pública digital de la obra (por ejemplo Webcast) licenciada bajo licencias generales, si la interpretación o ejecución de la obra está primordialmente orientada por o dirigida a la obtención de una ventaja comercial o una compensación monetaria privada.

ii.	Regalías por Fonogramas. El Licenciante se reserva el derecho exclusivo de recolectar, individualmente o a través de una sociedad de gestión colectiva de derechos de autor y derechos conexos (por ejemplo, los consagrados por la SAYCO), una agencia de derechos musicales o algún agente designado, las regalías por cualquier fonograma que Usted cree a partir de la obra (“versión cover”) y distribuya, en los términos del régimen de derechos de autor, si la creación o distribución de esa versión cover está primordialmente destinada o dirigida a obtener una ventaja comercial o una compensación monetaria privada.

e.	Gestión de Derechos de Autor sobre Interpretaciones y Ejecuciones Digitales (WebCasting). Para evitar toda confusión, el Licenciante aclara que, cuando la obra sea un fonograma, el Licenciante se reserva el derecho exclusivo de autorizar la ejecución pública digital de la obra (por ejemplo, webcast) y de recolectar, individualmente o a través de una sociedad de gestión colectiva de derechos de autor y derechos conexos (por ejemplo, ACINPRO), las regalías por la ejecución pública digital de la obra (por ejemplo, webcast), sujeta a las disposiciones aplicables del régimen de Derecho de Autor, si esta ejecución pública digital está primordialmente dirigida a obtener una ventaja comercial o una compensación monetaria privada.

5. Representaciones, Garantías y Limitaciones de Responsabilidad.
A MENOS QUE LAS PARTES LO ACORDARAN DE OTRA FORMA POR ESCRITO, EL LICENCIANTE OFRECE LA OBRA (EN EL ESTADO EN EL QUE SE ENCUENTRA) “TAL CUAL”, SIN BRINDAR GARANTÍAS DE CLASE ALGUNA RESPECTO DE LA OBRA, YA SEA EXPRESA, IMPLÍCITA, LEGAL O CUALQUIERA OTRA, INCLUYENDO, SIN LIMITARSE A ELLAS, GARANTÍAS DE TITULARIDAD, COMERCIABILIDAD, ADAPTABILIDAD O ADECUACIÓN A PROPÓSITO DETERMINADO, AUSENCIA DE INFRACCIÓN, DE AUSENCIA DE DEFECTOS LATENTES O DE OTRO TIPO, O LA PRESENCIA O AUSENCIA DE ERRORES, SEAN O NO DESCUBRIBLES (PUEDAN O NO SER ESTOS DESCUBIERTOS). ALGUNAS JURISDICCIONES NO PERMITEN LA EXCLUSIÓN DE GARANTÍAS IMPLÍCITAS, EN CUYO CASO ESTA EXCLUSIÓN PUEDE NO APLICARSE A USTED.

6. Limitación de responsabilidad.
A MENOS QUE LO EXIJA EXPRESAMENTE LA LEY APLICABLE, EL LICENCIANTE NO SERÁ RESPONSABLE ANTE USTED POR DAÑO ALGUNO, SEA POR RESPONSABILIDAD EXTRACONTRACTUAL, PRECONTRACTUAL O CONTRACTUAL, OBJETIVA O SUBJETIVA, SE TRATE DE DAÑOS MORALES O PATRIMONIALES, DIRECTOS O INDIRECTOS, PREVISTOS O IMPREVISTOS PRODUCIDOS POR EL USO DE ESTA LICENCIA O DE LA OBRA, AUN CUANDO EL LICENCIANTE HAYA SIDO ADVERTIDO DE LA POSIBILIDAD DE DICHOS DAÑOS. ALGUNAS LEYES NO PERMITEN LA EXCLUSIÓN DE CIERTA RESPONSABILIDAD, EN CUYO CASO ESTA EXCLUSIÓN PUEDE NO APLICARSE A USTED.

7. Término.

a.	Esta Licencia y los derechos otorgados en virtud de ella terminarán automáticamente si Usted infringe alguna condición establecida en ella. Sin embargo, los individuos o entidades que han recibido Obras Derivadas o Colectivas de Usted de conformidad con esta Licencia, no verán terminadas sus licencias, siempre que estos individuos o entidades sigan cumpliendo íntegramente las condiciones de estas licencias. Las Secciones 1, 2, 5, 6, 7, y 8 subsistirán a cualquier terminación de esta Licencia.

b.	Sujeta a las condiciones y términos anteriores, la licencia otorgada aquí es perpetua (durante el período de vigencia de los derechos de autor de la obra). No obstante lo anterior, el Licenciante se reserva el derecho a publicar y/o estrenar la Obra bajo condiciones de licencia diferentes o a dejar de distribuirla en los términos de esta Licencia en cualquier momento; en el entendido, sin embargo, que esa elección no servirá para revocar esta licencia o que deba ser otorgada , bajo los términos de esta licencia), y esta licencia continuará en pleno vigor y efecto a menos que sea terminada como se expresa atrás. La Licencia revocada continuará siendo plenamente vigente y efectiva si no se le da término en las condiciones indicadas anteriormente.

8. Varios.

a.	Cada vez que Usted distribuya o ponga a disposición pública la Obra o una Obra Colectiva, el Licenciante ofrecerá al destinatario una licencia en los mismos términos y condiciones que la licencia otorgada a Usted bajo esta Licencia.

b.	Si alguna disposición de esta Licencia resulta invalidada o no exigible, según la legislación vigente, esto no afectará ni la validez ni la aplicabilidad del resto de condiciones de esta Licencia y, sin acción adicional por parte de los sujetos de este acuerdo, aquélla se entenderá reformada lo mínimo necesario para hacer que dicha disposición sea válida y exigible.

c.	Ningún término o disposición de esta Licencia se estimará renunciada y ninguna violación de ella será consentida a menos que esa renuncia o consentimiento sea otorgado por escrito y firmado por la parte que renuncie o consienta.

d.	Esta Licencia refleja el acuerdo pleno entre las partes respecto a la Obra aquí licenciada. No hay arreglos, acuerdos o declaraciones respecto a la Obra que no estén especificados en este documento. El Licenciante no se verá limitado por ninguna disposición adicional que pueda surgir en alguna comunicación emanada de Usted. Esta Licencia no puede ser modificada sin el consentimiento mutuo por escrito del Licenciante y Usted.
0000-0001-7802-03173ed99bf75e8c26aaf5968cb25da0141d6000000-0002-0781-84411cd82259818901e72117a6c61da72b0f6000000-0001-9382-214X00644ca08291213271c11d23d82b8cb5600 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