Deep brain stimulation in the posteromedial hypothalamic nuclei in refractory aggressiveness: post-surgical results of 19 cases

Aggression is a clinical manifestation that usually occurs in neurodevelopmental disorders. In intellectual disability, dysfunctional behavior and aggressive and maladaptive responses are common. These facts put at risk the patient’s safety and cause discomfort in family members and caregivers (Gouv...

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Autores:
Benedetti, Juan Carlos
Camargo, Loida
GARGIULO, Pascual
López Velásquez, Norman Darío
Tipo de recurso:
Article of journal
Fecha de publicación:
2021
Institución:
Corporación Universidad de la Costa
Repositorio:
REDICUC - Repositorio CUC
Idioma:
eng
OAI Identifier:
oai:repositorio.cuc.edu.co:11323/8898
Acceso en línea:
https://hdl.handle.net/11323/8898
https://doi.org/10.1093/ijnp/pyab059
https://repositorio.cuc.edu.co/
Palabra clave:
Brain stimulation
Hypothalamic
Post-surgical
Rights
openAccess
License
CC0 1.0 Universal
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dc.title.spa.fl_str_mv Deep brain stimulation in the posteromedial hypothalamic nuclei in refractory aggressiveness: post-surgical results of 19 cases
title Deep brain stimulation in the posteromedial hypothalamic nuclei in refractory aggressiveness: post-surgical results of 19 cases
spellingShingle Deep brain stimulation in the posteromedial hypothalamic nuclei in refractory aggressiveness: post-surgical results of 19 cases
Brain stimulation
Hypothalamic
Post-surgical
title_short Deep brain stimulation in the posteromedial hypothalamic nuclei in refractory aggressiveness: post-surgical results of 19 cases
title_full Deep brain stimulation in the posteromedial hypothalamic nuclei in refractory aggressiveness: post-surgical results of 19 cases
title_fullStr Deep brain stimulation in the posteromedial hypothalamic nuclei in refractory aggressiveness: post-surgical results of 19 cases
title_full_unstemmed Deep brain stimulation in the posteromedial hypothalamic nuclei in refractory aggressiveness: post-surgical results of 19 cases
title_sort Deep brain stimulation in the posteromedial hypothalamic nuclei in refractory aggressiveness: post-surgical results of 19 cases
dc.creator.fl_str_mv Benedetti, Juan Carlos
Camargo, Loida
GARGIULO, Pascual
López Velásquez, Norman Darío
dc.contributor.author.spa.fl_str_mv Benedetti, Juan Carlos
Camargo, Loida
GARGIULO, Pascual
López Velásquez, Norman Darío
dc.subject.spa.fl_str_mv Brain stimulation
Hypothalamic
Post-surgical
topic Brain stimulation
Hypothalamic
Post-surgical
description Aggression is a clinical manifestation that usually occurs in neurodevelopmental disorders. In intellectual disability, dysfunctional behavior and aggressive and maladaptive responses are common. These facts put at risk the patient’s safety and cause discomfort in family members and caregivers (Gouveia et al., 2019). In general, drug prescription and behavioral therapy have favorable results in these individuals. However, there is a subset of patients who do not respond adequately to pharmacological and psychological treatment due to the severity of clinical symptoms and associated brain dysfunction (Torres et al., 2013) responsible for aggressive behavior. For this limited population of individuals, surgical interventions targeting the amygdala or hypothalamus have been proposed.
publishDate 2021
dc.date.accessioned.none.fl_str_mv 2021-11-23T19:18:31Z
dc.date.available.none.fl_str_mv 2021-11-23T19:18:31Z
dc.date.issued.none.fl_str_mv 2021
dc.type.spa.fl_str_mv Artículo de revista
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dc.identifier.issn.spa.fl_str_mv 1461-1457
1469-5111
dc.identifier.uri.spa.fl_str_mv https://hdl.handle.net/11323/8898
dc.identifier.doi.spa.fl_str_mv https://doi.org/10.1093/ijnp/pyab059
dc.identifier.instname.spa.fl_str_mv Corporación Universidad de la Costa
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identifier_str_mv 1461-1457
1469-5111
Corporación Universidad de la Costa
REDICUC - Repositorio CUC
url https://hdl.handle.net/11323/8898
https://doi.org/10.1093/ijnp/pyab059
https://repositorio.cuc.edu.co/
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.references.spa.fl_str_mv Ashkan K, Mirza AB, Tambirajoo K, Furlanetti L (2020) Deep brain stimulation in the management of paediatric neuropsychiatric conditions: current evidence and future directions. Eur J Paediatr Neurol 33:146–158.
Beszłej JA, Wieczorek T, Kobyłko A, Piotrowski P, Siwicki D, Weiser A, Fila-Witecka K, Rymaszewska J, Tabakow P (2019) Deep brain stimulation: new possibilities for the treatment of mental disorders. Psychiatr Pol 53:789–806.
Farrokhi F, Buchlak QD, Sikora M, Esmaili N, Marsans M, McLeod P, Mark J, Cox E, Bennett C, Carlson J (2020) Investigating risk factors and predicting complications in deep brain stimulation surgery with machine learning algorithms. World Neurosurg 134:e325–e338.
Franzini A, Marras C, Ferroli P, Bugiani O, Broggi G (2005) Stimulation of the posterior hypothalamus for medically intractable impulsive and violent behavior. Stereotact Funct Neurosurg 83:63–66.
Franzini A, Broggi G, Cordella R, Dones I, Messina G (2013) Deepbrain stimulation for aggressive and disruptive behavior. World Neurosurg 80:S29.e11–S29.e14.
Gouveia FV, Hamani C, Fonoff ET, Brentani H, Alho EJL, de Morais RMCB, de Souza AL, Rigonatti SP, Martinez RCR (2019) Amygdala and hypothalamus: historical overview with focus on aggression. Neurosurgery 85:11–30.
Micieli R, Rios AL, Aguilar RP, Posada LF, Hutchison WD (2017) Single-unit analysis of the human posterior hypothalamus and red nucleus during deep brain stimulation for aggressivity. J Neurosurg 126:1158–1164.
Silver JM, Yudofsky SC (1991) The Overt Aggression Scale: overview and guiding principles. J Neuropsychiatry Clin Neurosci 3:S22–S29.
Torres CV, Sola RG, Pastor J, Pedrosa M, Navas M, GarcíaNavarrete E, Ezquiaga E, García-Camba E (2013) Long-term results of posteromedial hypothalamic deep brain stimulation for patients with resistant aggressiveness. J Neurosurg 119:277–287.
Tsuboi T, Cif L, Coubes P, Ostrem JL, Romero DA, Miyagi Y, Lozano AM, De Vloo P, Haq I, Meng F, Sharma N, Ozelius LJ, Wagle Shukla A, Cauraugh JH, Foote KD, Okun MS (2020) Secondary worsening following DYT1 dystonia deep brain stimulation: a multi-country cohort. Front Hum Neurosci 14:242.
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dc.source.spa.fl_str_mv International Journal of Neuropsychopharmacology
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spelling Benedetti, Juan CarlosCamargo, LoidaGARGIULO, PascualLópez Velásquez, Norman Darío2021-11-23T19:18:31Z2021-11-23T19:18:31Z20211461-14571469-5111https://hdl.handle.net/11323/8898https://doi.org/10.1093/ijnp/pyab059Corporación Universidad de la CostaREDICUC - Repositorio CUChttps://repositorio.cuc.edu.co/Aggression is a clinical manifestation that usually occurs in neurodevelopmental disorders. In intellectual disability, dysfunctional behavior and aggressive and maladaptive responses are common. These facts put at risk the patient’s safety and cause discomfort in family members and caregivers (Gouveia et al., 2019). In general, drug prescription and behavioral therapy have favorable results in these individuals. However, there is a subset of patients who do not respond adequately to pharmacological and psychological treatment due to the severity of clinical symptoms and associated brain dysfunction (Torres et al., 2013) responsible for aggressive behavior. For this limited population of individuals, surgical interventions targeting the amygdala or hypothalamus have been proposed.Benedetti, Juan Carlos-will be generated-orcid-0000-0002-2307-6724-600Camargo, Loida-will be generated-orcid-0000-0003-0056-6832-600GARGIULO, Pascual-will be generated-orcid-0000-0003-2962-4346-600López Velásquez, Norman Darío-will be generated-orcid-0000-0003-1272-7429-600application/pdfengCorporación Universidad de la CostaCC0 1.0 Universalhttp://creativecommons.org/publicdomain/zero/1.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2International Journal of Neuropsychopharmacologyhttps://academic.oup.com/ijnp/advance-article/doi/10.1093/ijnp/pyab059/6358514Brain stimulationHypothalamicPost-surgicalDeep brain stimulation in the posteromedial hypothalamic nuclei in refractory aggressiveness: post-surgical results of 19 casesArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/acceptedVersionAshkan K, Mirza AB, Tambirajoo K, Furlanetti L (2020) Deep brain stimulation in the management of paediatric neuropsychiatric conditions: current evidence and future directions. Eur J Paediatr Neurol 33:146–158.Beszłej JA, Wieczorek T, Kobyłko A, Piotrowski P, Siwicki D, Weiser A, Fila-Witecka K, Rymaszewska J, Tabakow P (2019) Deep brain stimulation: new possibilities for the treatment of mental disorders. Psychiatr Pol 53:789–806.Farrokhi F, Buchlak QD, Sikora M, Esmaili N, Marsans M, McLeod P, Mark J, Cox E, Bennett C, Carlson J (2020) Investigating risk factors and predicting complications in deep brain stimulation surgery with machine learning algorithms. World Neurosurg 134:e325–e338.Franzini A, Marras C, Ferroli P, Bugiani O, Broggi G (2005) Stimulation of the posterior hypothalamus for medically intractable impulsive and violent behavior. Stereotact Funct Neurosurg 83:63–66.Franzini A, Broggi G, Cordella R, Dones I, Messina G (2013) Deepbrain stimulation for aggressive and disruptive behavior. World Neurosurg 80:S29.e11–S29.e14.Gouveia FV, Hamani C, Fonoff ET, Brentani H, Alho EJL, de Morais RMCB, de Souza AL, Rigonatti SP, Martinez RCR (2019) Amygdala and hypothalamus: historical overview with focus on aggression. Neurosurgery 85:11–30.Micieli R, Rios AL, Aguilar RP, Posada LF, Hutchison WD (2017) Single-unit analysis of the human posterior hypothalamus and red nucleus during deep brain stimulation for aggressivity. J Neurosurg 126:1158–1164.Silver JM, Yudofsky SC (1991) The Overt Aggression Scale: overview and guiding principles. J Neuropsychiatry Clin Neurosci 3:S22–S29.Torres CV, Sola RG, Pastor J, Pedrosa M, Navas M, GarcíaNavarrete E, Ezquiaga E, García-Camba E (2013) Long-term results of posteromedial hypothalamic deep brain stimulation for patients with resistant aggressiveness. J Neurosurg 119:277–287.Tsuboi T, Cif L, Coubes P, Ostrem JL, Romero DA, Miyagi Y, Lozano AM, De Vloo P, Haq I, Meng F, Sharma N, Ozelius LJ, Wagle Shukla A, Cauraugh JH, Foote KD, Okun MS (2020) Secondary worsening following DYT1 dystonia deep brain stimulation: a multi-country cohort. 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