Deep brain stimulation in the posteromedial hypothalamic nuclei in refractory aggressiveness: post-surgical results of 19 cases
Aggression is a clinical manifestation that usually occurs in neurodevelopmental disorders. In intellectual disability, dysfunctional behavior and aggressive and maladaptive responses are common. These facts put at risk the patient’s safety and cause discomfort in family members and caregivers (Gouv...
- Autores:
-
Benedetti, Juan Carlos
Camargo, Loida
GARGIULO, Pascual
López Velásquez, Norman Darío
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2021
- Institución:
- Corporación Universidad de la Costa
- Repositorio:
- REDICUC - Repositorio CUC
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.cuc.edu.co:11323/8898
- Acceso en línea:
- https://hdl.handle.net/11323/8898
https://doi.org/10.1093/ijnp/pyab059
https://repositorio.cuc.edu.co/
- Palabra clave:
- Brain stimulation
Hypothalamic
Post-surgical
- Rights
- openAccess
- License
- CC0 1.0 Universal
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dc.title.spa.fl_str_mv |
Deep brain stimulation in the posteromedial hypothalamic nuclei in refractory aggressiveness: post-surgical results of 19 cases |
title |
Deep brain stimulation in the posteromedial hypothalamic nuclei in refractory aggressiveness: post-surgical results of 19 cases |
spellingShingle |
Deep brain stimulation in the posteromedial hypothalamic nuclei in refractory aggressiveness: post-surgical results of 19 cases Brain stimulation Hypothalamic Post-surgical |
title_short |
Deep brain stimulation in the posteromedial hypothalamic nuclei in refractory aggressiveness: post-surgical results of 19 cases |
title_full |
Deep brain stimulation in the posteromedial hypothalamic nuclei in refractory aggressiveness: post-surgical results of 19 cases |
title_fullStr |
Deep brain stimulation in the posteromedial hypothalamic nuclei in refractory aggressiveness: post-surgical results of 19 cases |
title_full_unstemmed |
Deep brain stimulation in the posteromedial hypothalamic nuclei in refractory aggressiveness: post-surgical results of 19 cases |
title_sort |
Deep brain stimulation in the posteromedial hypothalamic nuclei in refractory aggressiveness: post-surgical results of 19 cases |
dc.creator.fl_str_mv |
Benedetti, Juan Carlos Camargo, Loida GARGIULO, Pascual López Velásquez, Norman Darío |
dc.contributor.author.spa.fl_str_mv |
Benedetti, Juan Carlos Camargo, Loida GARGIULO, Pascual López Velásquez, Norman Darío |
dc.subject.spa.fl_str_mv |
Brain stimulation Hypothalamic Post-surgical |
topic |
Brain stimulation Hypothalamic Post-surgical |
description |
Aggression is a clinical manifestation that usually occurs in neurodevelopmental disorders. In intellectual disability, dysfunctional behavior and aggressive and maladaptive responses are common. These facts put at risk the patient’s safety and cause discomfort in family members and caregivers (Gouveia et al., 2019). In general, drug prescription and behavioral therapy have favorable results in these individuals. However, there is a subset of patients who do not respond adequately to pharmacological and psychological treatment due to the severity of clinical symptoms and associated brain dysfunction (Torres et al., 2013) responsible for aggressive behavior. For this limited population of individuals, surgical interventions targeting the amygdala or hypothalamus have been proposed. |
publishDate |
2021 |
dc.date.accessioned.none.fl_str_mv |
2021-11-23T19:18:31Z |
dc.date.available.none.fl_str_mv |
2021-11-23T19:18:31Z |
dc.date.issued.none.fl_str_mv |
2021 |
dc.type.spa.fl_str_mv |
Artículo de revista |
dc.type.coar.fl_str_mv |
http://purl.org/coar/resource_type/c_2df8fbb1 |
dc.type.coar.spa.fl_str_mv |
http://purl.org/coar/resource_type/c_6501 |
dc.type.content.spa.fl_str_mv |
Text |
dc.type.driver.spa.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.redcol.spa.fl_str_mv |
http://purl.org/redcol/resource_type/ART |
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acceptedVersion |
dc.identifier.issn.spa.fl_str_mv |
1461-1457 1469-5111 |
dc.identifier.uri.spa.fl_str_mv |
https://hdl.handle.net/11323/8898 |
dc.identifier.doi.spa.fl_str_mv |
https://doi.org/10.1093/ijnp/pyab059 |
dc.identifier.instname.spa.fl_str_mv |
Corporación Universidad de la Costa |
dc.identifier.reponame.spa.fl_str_mv |
REDICUC - Repositorio CUC |
dc.identifier.repourl.spa.fl_str_mv |
https://repositorio.cuc.edu.co/ |
identifier_str_mv |
1461-1457 1469-5111 Corporación Universidad de la Costa REDICUC - Repositorio CUC |
url |
https://hdl.handle.net/11323/8898 https://doi.org/10.1093/ijnp/pyab059 https://repositorio.cuc.edu.co/ |
dc.language.iso.none.fl_str_mv |
eng |
language |
eng |
dc.relation.references.spa.fl_str_mv |
Ashkan K, Mirza AB, Tambirajoo K, Furlanetti L (2020) Deep brain stimulation in the management of paediatric neuropsychiatric conditions: current evidence and future directions. Eur J Paediatr Neurol 33:146–158. Beszłej JA, Wieczorek T, Kobyłko A, Piotrowski P, Siwicki D, Weiser A, Fila-Witecka K, Rymaszewska J, Tabakow P (2019) Deep brain stimulation: new possibilities for the treatment of mental disorders. Psychiatr Pol 53:789–806. Farrokhi F, Buchlak QD, Sikora M, Esmaili N, Marsans M, McLeod P, Mark J, Cox E, Bennett C, Carlson J (2020) Investigating risk factors and predicting complications in deep brain stimulation surgery with machine learning algorithms. World Neurosurg 134:e325–e338. Franzini A, Marras C, Ferroli P, Bugiani O, Broggi G (2005) Stimulation of the posterior hypothalamus for medically intractable impulsive and violent behavior. Stereotact Funct Neurosurg 83:63–66. Franzini A, Broggi G, Cordella R, Dones I, Messina G (2013) Deepbrain stimulation for aggressive and disruptive behavior. World Neurosurg 80:S29.e11–S29.e14. Gouveia FV, Hamani C, Fonoff ET, Brentani H, Alho EJL, de Morais RMCB, de Souza AL, Rigonatti SP, Martinez RCR (2019) Amygdala and hypothalamus: historical overview with focus on aggression. Neurosurgery 85:11–30. Micieli R, Rios AL, Aguilar RP, Posada LF, Hutchison WD (2017) Single-unit analysis of the human posterior hypothalamus and red nucleus during deep brain stimulation for aggressivity. J Neurosurg 126:1158–1164. Silver JM, Yudofsky SC (1991) The Overt Aggression Scale: overview and guiding principles. J Neuropsychiatry Clin Neurosci 3:S22–S29. Torres CV, Sola RG, Pastor J, Pedrosa M, Navas M, GarcíaNavarrete E, Ezquiaga E, García-Camba E (2013) Long-term results of posteromedial hypothalamic deep brain stimulation for patients with resistant aggressiveness. J Neurosurg 119:277–287. Tsuboi T, Cif L, Coubes P, Ostrem JL, Romero DA, Miyagi Y, Lozano AM, De Vloo P, Haq I, Meng F, Sharma N, Ozelius LJ, Wagle Shukla A, Cauraugh JH, Foote KD, Okun MS (2020) Secondary worsening following DYT1 dystonia deep brain stimulation: a multi-country cohort. Front Hum Neurosci 14:242. |
dc.rights.spa.fl_str_mv |
CC0 1.0 Universal |
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http://creativecommons.org/publicdomain/zero/1.0/ |
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openAccess |
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application/pdf |
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Corporación Universidad de la Costa |
dc.source.spa.fl_str_mv |
International Journal of Neuropsychopharmacology |
institution |
Corporación Universidad de la Costa |
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Benedetti, Juan CarlosCamargo, LoidaGARGIULO, PascualLópez Velásquez, Norman Darío2021-11-23T19:18:31Z2021-11-23T19:18:31Z20211461-14571469-5111https://hdl.handle.net/11323/8898https://doi.org/10.1093/ijnp/pyab059Corporación Universidad de la CostaREDICUC - Repositorio CUChttps://repositorio.cuc.edu.co/Aggression is a clinical manifestation that usually occurs in neurodevelopmental disorders. In intellectual disability, dysfunctional behavior and aggressive and maladaptive responses are common. These facts put at risk the patient’s safety and cause discomfort in family members and caregivers (Gouveia et al., 2019). In general, drug prescription and behavioral therapy have favorable results in these individuals. However, there is a subset of patients who do not respond adequately to pharmacological and psychological treatment due to the severity of clinical symptoms and associated brain dysfunction (Torres et al., 2013) responsible for aggressive behavior. For this limited population of individuals, surgical interventions targeting the amygdala or hypothalamus have been proposed.Benedetti, Juan Carlos-will be generated-orcid-0000-0002-2307-6724-600Camargo, Loida-will be generated-orcid-0000-0003-0056-6832-600GARGIULO, Pascual-will be generated-orcid-0000-0003-2962-4346-600López Velásquez, Norman Darío-will be generated-orcid-0000-0003-1272-7429-600application/pdfengCorporación Universidad de la CostaCC0 1.0 Universalhttp://creativecommons.org/publicdomain/zero/1.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2International Journal of Neuropsychopharmacologyhttps://academic.oup.com/ijnp/advance-article/doi/10.1093/ijnp/pyab059/6358514Brain stimulationHypothalamicPost-surgicalDeep brain stimulation in the posteromedial hypothalamic nuclei in refractory aggressiveness: post-surgical results of 19 casesArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/acceptedVersionAshkan K, Mirza AB, Tambirajoo K, Furlanetti L (2020) Deep brain stimulation in the management of paediatric neuropsychiatric conditions: current evidence and future directions. Eur J Paediatr Neurol 33:146–158.Beszłej JA, Wieczorek T, Kobyłko A, Piotrowski P, Siwicki D, Weiser A, Fila-Witecka K, Rymaszewska J, Tabakow P (2019) Deep brain stimulation: new possibilities for the treatment of mental disorders. Psychiatr Pol 53:789–806.Farrokhi F, Buchlak QD, Sikora M, Esmaili N, Marsans M, McLeod P, Mark J, Cox E, Bennett C, Carlson J (2020) Investigating risk factors and predicting complications in deep brain stimulation surgery with machine learning algorithms. World Neurosurg 134:e325–e338.Franzini A, Marras C, Ferroli P, Bugiani O, Broggi G (2005) Stimulation of the posterior hypothalamus for medically intractable impulsive and violent behavior. Stereotact Funct Neurosurg 83:63–66.Franzini A, Broggi G, Cordella R, Dones I, Messina G (2013) Deepbrain stimulation for aggressive and disruptive behavior. World Neurosurg 80:S29.e11–S29.e14.Gouveia FV, Hamani C, Fonoff ET, Brentani H, Alho EJL, de Morais RMCB, de Souza AL, Rigonatti SP, Martinez RCR (2019) Amygdala and hypothalamus: historical overview with focus on aggression. Neurosurgery 85:11–30.Micieli R, Rios AL, Aguilar RP, Posada LF, Hutchison WD (2017) Single-unit analysis of the human posterior hypothalamus and red nucleus during deep brain stimulation for aggressivity. J Neurosurg 126:1158–1164.Silver JM, Yudofsky SC (1991) The Overt Aggression Scale: overview and guiding principles. J Neuropsychiatry Clin Neurosci 3:S22–S29.Torres CV, Sola RG, Pastor J, Pedrosa M, Navas M, GarcíaNavarrete E, Ezquiaga E, García-Camba E (2013) Long-term results of posteromedial hypothalamic deep brain stimulation for patients with resistant aggressiveness. J Neurosurg 119:277–287.Tsuboi T, Cif L, Coubes P, Ostrem JL, Romero DA, Miyagi Y, Lozano AM, De Vloo P, Haq I, Meng F, Sharma N, Ozelius LJ, Wagle Shukla A, Cauraugh JH, Foote KD, Okun MS (2020) Secondary worsening following DYT1 dystonia deep brain stimulation: a multi-country cohort. 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