Costs and trends in the usage of biological therapy for rheumatoid arthritis - a retrospective study

Objectives: The aim of this study was to identify the risk of depression and assess the relationship between comorbid depression, healthcare utilization and healthcare expenditures in patients with rheumatoid arthritis (RA). Methods: We used 2015 Medical Expenditure Panel Survey (MEPS) to identify p...

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Autores:
Santos-Moreno, P
Buitrago-Garcia, D
Villarreal, L
Alvis-Zakzuk, N
Carrasquilla, M
Alvis Guzman, N
Tipo de recurso:
Article of journal
Fecha de publicación:
2018
Institución:
Corporación Universidad de la Costa
Repositorio:
REDICUC - Repositorio CUC
Idioma:
eng
OAI Identifier:
oai:repositorio.cuc.edu.co:11323/4701
Acceso en línea:
http://hdl.handle.net/11323/4701
https://repositorio.cuc.edu.co/
Palabra clave:
Riesgo de depresión
Asistencia sanitaria
Risk of depression
Healthcare
Rights
openAccess
License
Attribution-NonCommercial-ShareAlike 4.0 International
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dc.title.spa.fl_str_mv Costs and trends in the usage of biological therapy for rheumatoid arthritis - a retrospective study
dc.title.translated.spa.fl_str_mv Costos y tendencias en el uso de la terapia biológica para la artritis reumatoide: un estudio retrospectivo
title Costs and trends in the usage of biological therapy for rheumatoid arthritis - a retrospective study
spellingShingle Costs and trends in the usage of biological therapy for rheumatoid arthritis - a retrospective study
Riesgo de depresión
Asistencia sanitaria
Risk of depression
Healthcare
title_short Costs and trends in the usage of biological therapy for rheumatoid arthritis - a retrospective study
title_full Costs and trends in the usage of biological therapy for rheumatoid arthritis - a retrospective study
title_fullStr Costs and trends in the usage of biological therapy for rheumatoid arthritis - a retrospective study
title_full_unstemmed Costs and trends in the usage of biological therapy for rheumatoid arthritis - a retrospective study
title_sort Costs and trends in the usage of biological therapy for rheumatoid arthritis - a retrospective study
dc.creator.fl_str_mv Santos-Moreno, P
Buitrago-Garcia, D
Villarreal, L
Alvis-Zakzuk, N
Carrasquilla, M
Alvis Guzman, N
dc.contributor.author.spa.fl_str_mv Santos-Moreno, P
Buitrago-Garcia, D
Villarreal, L
Alvis-Zakzuk, N
Carrasquilla, M
Alvis Guzman, N
dc.subject.spa.fl_str_mv Riesgo de depresión
Asistencia sanitaria
Risk of depression
Healthcare
topic Riesgo de depresión
Asistencia sanitaria
Risk of depression
Healthcare
description Objectives: The aim of this study was to identify the risk of depression and assess the relationship between comorbid depression, healthcare utilization and healthcare expenditures in patients with rheumatoid arthritis (RA). Methods: We used 2015 Medical Expenditure Panel Survey (MEPS) to identify patients with RA and depression. The risk of being depressed was estimated using multiple logistic regression with survey weights. Generalized linear regression was employed to evaluate whether depression is statistically significantly associated with increased utilization and cost for office-based provider care, hospital outpatient care, hospital inpatient care, emergency room care and prescription medications. The results were adjusted for age, sex, race, marital status, education, health insurance, metropolitan area status, region, income level, and comorbidities. Results: A total number of 6,290 RA patients were identified from 2015 MEPS data set, representing a population size of 244,515,143. Of all the RA patients in 2015, 1,163 were found to have medical records of comorbid depression. Patients with RA were 2.1 times more likely to be depressed after adjusting for confounding variables (95%CI 1.80-2.42). Depressed patients had more office-based visits (p emergency room visits (p=0.0136), hospital admissions (p=0.0330), filled more prescriptions (p spent more on outpatient care (p=0.001), prescription medications (p=0.0003) compared to their counterparts. The difference in total health care cost per person was around $4,000. Conclusions: RA is associated with an increased cost and utilization of health care. Collaborative care might be indicated for future cost savings
publishDate 2018
dc.date.issued.none.fl_str_mv 2018
dc.date.accessioned.none.fl_str_mv 2019-05-27T12:36:48Z
dc.date.available.none.fl_str_mv 2019-05-27T12:36:48Z
dc.type.spa.fl_str_mv Artículo de revista
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dc.type.content.spa.fl_str_mv Text
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dc.identifier.uri.spa.fl_str_mv http://hdl.handle.net/11323/4701
dc.identifier.instname.spa.fl_str_mv Corporación Universidad de la Costa
dc.identifier.reponame.spa.fl_str_mv REDICUC - Repositorio CUC
dc.identifier.repourl.spa.fl_str_mv https://repositorio.cuc.edu.co/
url http://hdl.handle.net/11323/4701
https://repositorio.cuc.edu.co/
identifier_str_mv Corporación Universidad de la Costa
REDICUC - Repositorio CUC
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.ispartof.spa.fl_str_mv https://doi.org/10.1016/j.jval.2018.04.1328
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dc.publisher.spa.fl_str_mv VALUE IN HEALTH 21
institution Corporación Universidad de la Costa
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spelling Santos-Moreno, PBuitrago-Garcia, DVillarreal, LAlvis-Zakzuk, NCarrasquilla, MAlvis Guzman, N2019-05-27T12:36:48Z2019-05-27T12:36:48Z2018http://hdl.handle.net/11323/4701Corporación Universidad de la CostaREDICUC - Repositorio CUChttps://repositorio.cuc.edu.co/Objectives: The aim of this study was to identify the risk of depression and assess the relationship between comorbid depression, healthcare utilization and healthcare expenditures in patients with rheumatoid arthritis (RA). Methods: We used 2015 Medical Expenditure Panel Survey (MEPS) to identify patients with RA and depression. The risk of being depressed was estimated using multiple logistic regression with survey weights. Generalized linear regression was employed to evaluate whether depression is statistically significantly associated with increased utilization and cost for office-based provider care, hospital outpatient care, hospital inpatient care, emergency room care and prescription medications. The results were adjusted for age, sex, race, marital status, education, health insurance, metropolitan area status, region, income level, and comorbidities. Results: A total number of 6,290 RA patients were identified from 2015 MEPS data set, representing a population size of 244,515,143. Of all the RA patients in 2015, 1,163 were found to have medical records of comorbid depression. Patients with RA were 2.1 times more likely to be depressed after adjusting for confounding variables (95%CI 1.80-2.42). Depressed patients had more office-based visits (p emergency room visits (p=0.0136), hospital admissions (p=0.0330), filled more prescriptions (p spent more on outpatient care (p=0.001), prescription medications (p=0.0003) compared to their counterparts. The difference in total health care cost per person was around $4,000. Conclusions: RA is associated with an increased cost and utilization of health care. Collaborative care might be indicated for future cost savingsObjetivos: El objetivo de este estudio fue identificar el riesgo de depresión y evaluar la relación entre la depresión comórbida, la utilización de la asistencia sanitaria y los gastos de asistencia sanitaria en pacientes con artritis reumatoide (AR). Métodos: utilizamos la Encuesta de Panel de Gastos Médicos 2015 (MEPS) para identificar a los pacientes con AR y depresión. El riesgo de depresión se estimó mediante regresión logística múltiple con ponderaciones de la encuesta. Se empleó una regresión lineal generalizada para evaluar si la depresión se asocia estadísticamente de manera significativa con el aumento de la utilización y el costo de la atención de un proveedor en el consultorio, la atención ambulatoria en el hospital, la atención hospitalaria para pacientes hospitalizados, la atención en la sala de emergencia y los medicamentos recetados. Los resultados se ajustaron por edad, sexo, raza, estado civil, educación, seguro de salud, estado del área metropolitana, región, nivel de ingresos y comorbilidades. Resultados: Se identificó un número total de 6,290 pacientes con AR a partir del conjunto de datos de MEPS 2015, que representa un tamaño de población de 244,515,143. De todos los pacientes con AR en 2015, se encontró que 1.163 tenían registros médicos de depresión comórbida. Los pacientes con AR tenían 2.1 veces más probabilidades de estar deprimidos después de ajustar las variables de confusión (IC 95% 1.80-2.42). Los pacientes deprimidos tuvieron más consultas en el consultorio (p visitas a la sala de emergencias (p = 0.0136), ingresos hospitalarios (p = 0.0330), surtieron más recetas (p gastaron más en atención ambulatoria (p = 0.001), medicamentos recetados (p = 0.0003) En comparación con sus homólogos, la diferencia en el costo total de atención médica por persona fue de alrededor de $ 4,000. Conclusiones: la AR se asocia con un aumento en el costo y la utilización de la atención médica. El cuidado colaborativo podría estar indicado para futuros ahorros de costos.Santos-Moreno, P-4c8bf522-fd2f-4d0d-bd00-433bf39bccbf-0Buitrago-Garcia, D-f72f35bb-b832-4224-b846-95d3948c1509-0Villarreal, L-0e7db4bd-aaff-42eb-b6c7-f475dbb3fe50-0Alvis-Zakzuk, N-4ad43f03-69e9-4fe7-b60d-070645964218-0Carrasquilla, M-c777b5bf-3e08-468d-9bb7-9fdd4a8f5e28-0Alvis Guzman, N-2d13fafb-f99f-45da-90f0-c24f33bc4418-0engVALUE IN HEALTH 21https://doi.org/10.1016/j.jval.2018.04.1328Attribution-NonCommercial-ShareAlike 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-sa/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Riesgo de depresiónAsistencia sanitariaRisk of depressionHealthcareCosts and trends in the usage of biological therapy for rheumatoid arthritis - a retrospective studyCostos y tendencias en el uso de la terapia biológica para la artritis reumatoide: un estudio retrospectivoArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/acceptedVersionPublicationORIGINALThe Cost of Comorbid Depression Among Patients with Rheumatoid.pdfThe Cost of Comorbid Depression Among Patients with Rheumatoid.pdfapplication/pdf75119https://repositorio.cuc.edu.co/bitstreams/f18d0f7b-06b0-4337-bad1-ceb25215bdf7/download1cc375689839b5e4330cca3a33858adcMD51CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-81031https://repositorio.cuc.edu.co/bitstreams/d7dd7155-b5bd-438c-87ed-46c84431d93e/download934f4ca17e109e0a05eaeaba504d7ce4MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://repositorio.cuc.edu.co/bitstreams/12234853-d6fe-470b-bdec-e3a62d382bb3/download8a4605be74aa9ea9d79846c1fba20a33MD53THUMBNAILThe Cost of Comorbid Depression Among Patients with Rheumatoid.pdf.jpgThe Cost of Comorbid Depression Among Patients with Rheumatoid.pdf.jpgimage/jpeg85099https://repositorio.cuc.edu.co/bitstreams/65381f01-cf1f-490a-aaa1-b58011cfa671/download8b9044a09a3046caae928c57667b9769MD55TEXTThe Cost of Comorbid Depression Among Patients with Rheumatoid.pdf.txtThe Cost of Comorbid Depression Among Patients with Rheumatoid.pdf.txttext/plain13059https://repositorio.cuc.edu.co/bitstreams/09cf14b8-791e-4ccd-afb5-1ed9a17c0133/downloadcef4af5bc4ec60933b7e7f9493966b24MD5611323/4701oai:repositorio.cuc.edu.co:11323/47012024-09-16 16:45:42.6http://creativecommons.org/licenses/by-nc-sa/4.0/Attribution-NonCommercial-ShareAlike 4.0 Internationalopen.accesshttps://repositorio.cuc.edu.coRepositorio de la Universidad de la Costa CUCrepdigital@cuc.edu.coTk9URTogUExBQ0UgWU9VUiBPV04gTElDRU5TRSBIRVJFClRoaXMgc2FtcGxlIGxpY2Vuc2UgaXMgcHJvdmlkZWQgZm9yIGluZm9ybWF0aW9uYWwgcHVycG9zZXMgb25seS4KCk5PTi1FWENMVVNJVkUgRElTVFJJQlVUSU9OIExJQ0VOU0UKCkJ5IHNpZ25pbmcgYW5kIHN1Ym1pdHRpbmcgdGhpcyBsaWNlbnNlLCB5b3UgKHRoZSBhdXRob3Iocykgb3IgY29weXJpZ2h0Cm93bmVyKSBncmFudHMgdG8gRFNwYWNlIFVuaXZlcnNpdHkgKERTVSkgdGhlIG5vbi1leGNsdXNpdmUgcmlnaHQgdG8gcmVwcm9kdWNlLAp0cmFuc2xhdGUgKGFzIGRlZmluZWQgYmVsb3cpLCBhbmQvb3IgZGlzdHJpYnV0ZSB5b3VyIHN1Ym1pc3Npb24gKGluY2x1ZGluZwp0aGUgYWJzdHJhY3QpIHdvcmxkd2lkZSBpbiBwcmludCBhbmQgZWxlY3Ryb25pYyBmb3JtYXQgYW5kIGluIGFueSBtZWRpdW0sCmluY2x1ZGluZyBidXQgbm90IGxpbWl0ZWQgdG8gYXVkaW8gb3IgdmlkZW8uCgpZb3UgYWdyZWUgdGhhdCBEU1UgbWF5LCB3aXRob3V0IGNoYW5naW5nIHRoZSBjb250ZW50LCB0cmFuc2xhdGUgdGhlCnN1Ym1pc3Npb24gdG8gYW55IG1lZGl1bSBvciBmb3JtYXQgZm9yIHRoZSBwdXJwb3NlIG9mIHByZXNlcnZhdGlvbi4KCllvdSBhbHNvIGFncmVlIHRoYXQgRFNVIG1heSBrZWVwIG1vcmUgdGhhbiBvbmUgY29weSBvZiB0aGlzIHN1Ym1pc3Npb24gZm9yCnB1cnBvc2VzIG9mIHNlY3VyaXR5LCBiYWNrLXVwIGFuZCBwcmVzZXJ2YXRpb24uCgpZb3UgcmVwcmVzZW50IHRoYXQgdGhlIHN1Ym1pc3Npb24gaXMgeW91ciBvcmlnaW5hbCB3b3JrLCBhbmQgdGhhdCB5b3UgaGF2ZQp0aGUgcmlnaHQgdG8gZ3JhbnQgdGhlIHJpZ2h0cyBjb250YWluZWQgaW4gdGhpcyBsaWNlbnNlLiBZb3UgYWxzbyByZXByZXNlbnQKdGhhdCB5b3VyIHN1Ym1pc3Npb24gZG9lcyBub3QsIHRvIHRoZSBiZXN0IG9mIHlvdXIga25vd2xlZGdlLCBpbmZyaW5nZSB1cG9uCmFueW9uZSdzIGNvcHlyaWdodC4KCklmIHRoZSBzdWJtaXNzaW9uIGNvbnRhaW5zIG1hdGVyaWFsIGZvciB3aGljaCB5b3UgZG8gbm90IGhvbGQgY29weXJpZ2h0LAp5b3UgcmVwcmVzZW50IHRoYXQgeW91IGhhdmUgb2J0YWluZWQgdGhlIHVucmVzdHJpY3RlZCBwZXJtaXNzaW9uIG9mIHRoZQpjb3B5cmlnaHQgb3duZXIgdG8gZ3JhbnQgRFNVIHRoZSByaWdodHMgcmVxdWlyZWQgYnkgdGhpcyBsaWNlbnNlLCBhbmQgdGhhdApzdWNoIHRoaXJkLXBhcnR5IG93bmVkIG1hdGVyaWFsIGlzIGNsZWFybHkgaWRlbnRpZmllZCBhbmQgYWNrbm93bGVkZ2VkCndpdGhpbiB0aGUgdGV4dCBvciBjb250ZW50IG9mIHRoZSBzdWJtaXNzaW9uLgoKSUYgVEhFIFNVQk1JU1NJT04gSVMgQkFTRUQgVVBPTiBXT1JLIFRIQVQgSEFTIEJFRU4gU1BPTlNPUkVEIE9SIFNVUFBPUlRFRApCWSBBTiBBR0VOQ1kgT1IgT1JHQU5JWkFUSU9OIE9USEVSIFRIQU4gRFNVLCBZT1UgUkVQUkVTRU5UIFRIQVQgWU9VIEhBVkUKRlVMRklMTEVEIEFOWSBSSUdIVCBPRiBSRVZJRVcgT1IgT1RIRVIgT0JMSUdBVElPTlMgUkVRVUlSRUQgQlkgU1VDSApDT05UUkFDVCBPUiBBR1JFRU1FTlQuCgpEU1Ugd2lsbCBjbGVhcmx5IGlkZW50aWZ5IHlvdXIgbmFtZShzKSBhcyB0aGUgYXV0aG9yKHMpIG9yIG93bmVyKHMpIG9mIHRoZQpzdWJtaXNzaW9uLCBhbmQgd2lsbCBub3QgbWFrZSBhbnkgYWx0ZXJhdGlvbiwgb3RoZXIgdGhhbiBhcyBhbGxvd2VkIGJ5IHRoaXMKbGljZW5zZSwgdG8geW91ciBzdWJtaXNzaW9uLgo=