Antibiotic resistance of airborne viable bacteria and size distribution in neonatal intensive care units
Despite their significant impact on public health, antibiotic resistance and size distributions of airborne viable bacteria in indoor environments in neonatal intensive care units (NICU) remain understudied. Therefore, the objective of this study was to assess the antibiotic resistance of airborne v...
- Autores:
-
MORGADO GAMERO, WENDY BEATRIZ
Mendoza Hernandez, Martha
Castillo Ramirez, Margarita
MEDINA ALTAHONA, JHORMA JOSE
La Hoz Theuer, Stephanie
Posso Mendoza, Heidy
Parody, Alexander
Teixeira, Elba C.
Agudelo-Castañeda, Dayana Milena
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2019
- Institución:
- Corporación Universidad de la Costa
- Repositorio:
- REDICUC - Repositorio CUC
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.cuc.edu.co:11323/5393
- Acceso en línea:
- https://hdl.handle.net/11323/5393
https://repositorio.cuc.edu.co/
- Palabra clave:
- Bioaerosols
Neonatal intensive care unit
Antibiotic resistance
Public health
- Rights
- openAccess
- License
- CC0 1.0 Universal
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| dc.title.spa.fl_str_mv |
Antibiotic resistance of airborne viable bacteria and size distribution in neonatal intensive care units |
| title |
Antibiotic resistance of airborne viable bacteria and size distribution in neonatal intensive care units |
| spellingShingle |
Antibiotic resistance of airborne viable bacteria and size distribution in neonatal intensive care units Bioaerosols Neonatal intensive care unit Antibiotic resistance Public health |
| title_short |
Antibiotic resistance of airborne viable bacteria and size distribution in neonatal intensive care units |
| title_full |
Antibiotic resistance of airborne viable bacteria and size distribution in neonatal intensive care units |
| title_fullStr |
Antibiotic resistance of airborne viable bacteria and size distribution in neonatal intensive care units |
| title_full_unstemmed |
Antibiotic resistance of airborne viable bacteria and size distribution in neonatal intensive care units |
| title_sort |
Antibiotic resistance of airborne viable bacteria and size distribution in neonatal intensive care units |
| dc.creator.fl_str_mv |
MORGADO GAMERO, WENDY BEATRIZ Mendoza Hernandez, Martha Castillo Ramirez, Margarita MEDINA ALTAHONA, JHORMA JOSE La Hoz Theuer, Stephanie Posso Mendoza, Heidy Parody, Alexander Teixeira, Elba C. Agudelo-Castañeda, Dayana Milena |
| dc.contributor.author.spa.fl_str_mv |
MORGADO GAMERO, WENDY BEATRIZ Mendoza Hernandez, Martha Castillo Ramirez, Margarita MEDINA ALTAHONA, JHORMA JOSE La Hoz Theuer, Stephanie Posso Mendoza, Heidy Parody, Alexander Teixeira, Elba C. Agudelo-Castañeda, Dayana Milena |
| dc.subject.spa.fl_str_mv |
Bioaerosols Neonatal intensive care unit Antibiotic resistance Public health |
| topic |
Bioaerosols Neonatal intensive care unit Antibiotic resistance Public health |
| description |
Despite their significant impact on public health, antibiotic resistance and size distributions of airborne viable bacteria in indoor environments in neonatal intensive care units (NICU) remain understudied. Therefore, the objective of this study was to assess the antibiotic resistance of airborne viable bacteria for different sizes (0.65–7 µm) in private-style and public-style neonatal intensive care units (NICU). Airborne bacteria concentrations were assessed by a six-stage Andersen impactor, operating at 28.3 L/min. Public-style NICU revealed higher concentrations of airborne viable bacteria (53.00 to 214.37 CFU/m3) than private-style NICU (151.94–466.43), indicating a possible threat to health. In the public-style NICU, Staphylococcus was the highest bacterial genera identified in the present study, were Staphylococcus saprophyticus and Staphylococcus epidermidis predominated, especially in the second bronchi and alveoli size ranges. Alloiococcus otitidis, Bacillus subtiles, Bacillus thuringiensis, Kocuria rosea, and Pseudomonas pseudoalcaligene, were identified in the alveoli size range. In NICU#2, eight species were identified in the alveoli size range: Bacillus cereus, Bacillus subtilis, Bacillus thuringiensis, Eikenella corrodens, Pseudomonas aeruginosa, Staphylococcus aureus, Staphylococcus epidermidis, and Streptococcus gordoni. Multi-drug-resistant organisms (MDROs) were found in both of the NICUs. Bacillus cereus strains were resistant to Ampicillin, Cefoxitin, Ceftaroline, and Penicillin G. Staphylococcus cohnii ssp. cohnii was resistant in parallel to ampicillin and G penicillin. Staphylococcus saprophyticus strains were resistant to Ampicillin, Penicillin G, Oxaxilin, and Erythromycin. Results may indicate a potential threat to human health due to the airborne bacteria concentration and their antibiotic resistance ability. The results may provide evidence for the need of interventions to reduce indoor airborne particle concentrations and their transfer to premature infants with underdeveloped immune systems, even though protocols for visitors and cleaning are well-established. |
| publishDate |
2019 |
| dc.date.accessioned.none.fl_str_mv |
2019-10-02T15:29:12Z |
| dc.date.available.none.fl_str_mv |
2019-10-02T15:29:12Z |
| dc.date.issued.none.fl_str_mv |
2019-09-10 |
| dc.type.spa.fl_str_mv |
Artículo de revista |
| dc.type.coar.fl_str_mv |
http://purl.org/coar/resource_type/c_2df8fbb1 |
| dc.type.coar.spa.fl_str_mv |
http://purl.org/coar/resource_type/c_6501 |
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Text |
| dc.type.driver.spa.fl_str_mv |
info:eu-repo/semantics/article |
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http://purl.org/redcol/resource_type/ART |
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info:eu-repo/semantics/acceptedVersion |
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http://purl.org/coar/resource_type/c_6501 |
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acceptedVersion |
| dc.identifier.issn.spa.fl_str_mv |
1661-7827 1660-4601 |
| dc.identifier.uri.spa.fl_str_mv |
https://hdl.handle.net/11323/5393 |
| dc.identifier.instname.spa.fl_str_mv |
Corporación Universidad de la Costa |
| dc.identifier.reponame.spa.fl_str_mv |
REDICUC - Repositorio CUC |
| dc.identifier.repourl.spa.fl_str_mv |
https://repositorio.cuc.edu.co/ |
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1661-7827 1660-4601 Corporación Universidad de la Costa REDICUC - Repositorio CUC |
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https://hdl.handle.net/11323/5393 https://repositorio.cuc.edu.co/ |
| dc.language.iso.none.fl_str_mv |
eng |
| language |
eng |
| dc.relation.ispartof.spa.fl_str_mv |
https://doi.org/10.3390/ijerph16183340 |
| dc.relation.references.spa.fl_str_mv |
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MORGADO GAMERO, WENDY BEATRIZMendoza Hernandez, MarthaCastillo Ramirez, MargaritaMEDINA ALTAHONA, JHORMA JOSELa Hoz Theuer, StephaniePosso Mendoza, HeidyParody, AlexanderTeixeira, Elba C.Agudelo-Castañeda, Dayana Milena2019-10-02T15:29:12Z2019-10-02T15:29:12Z2019-09-101661-78271660-4601https://hdl.handle.net/11323/5393Corporación Universidad de la CostaREDICUC - Repositorio CUChttps://repositorio.cuc.edu.co/Despite their significant impact on public health, antibiotic resistance and size distributions of airborne viable bacteria in indoor environments in neonatal intensive care units (NICU) remain understudied. Therefore, the objective of this study was to assess the antibiotic resistance of airborne viable bacteria for different sizes (0.65–7 µm) in private-style and public-style neonatal intensive care units (NICU). Airborne bacteria concentrations were assessed by a six-stage Andersen impactor, operating at 28.3 L/min. Public-style NICU revealed higher concentrations of airborne viable bacteria (53.00 to 214.37 CFU/m3) than private-style NICU (151.94–466.43), indicating a possible threat to health. In the public-style NICU, Staphylococcus was the highest bacterial genera identified in the present study, were Staphylococcus saprophyticus and Staphylococcus epidermidis predominated, especially in the second bronchi and alveoli size ranges. Alloiococcus otitidis, Bacillus subtiles, Bacillus thuringiensis, Kocuria rosea, and Pseudomonas pseudoalcaligene, were identified in the alveoli size range. In NICU#2, eight species were identified in the alveoli size range: Bacillus cereus, Bacillus subtilis, Bacillus thuringiensis, Eikenella corrodens, Pseudomonas aeruginosa, Staphylococcus aureus, Staphylococcus epidermidis, and Streptococcus gordoni. Multi-drug-resistant organisms (MDROs) were found in both of the NICUs. Bacillus cereus strains were resistant to Ampicillin, Cefoxitin, Ceftaroline, and Penicillin G. Staphylococcus cohnii ssp. cohnii was resistant in parallel to ampicillin and G penicillin. Staphylococcus saprophyticus strains were resistant to Ampicillin, Penicillin G, Oxaxilin, and Erythromycin. Results may indicate a potential threat to human health due to the airborne bacteria concentration and their antibiotic resistance ability. The results may provide evidence for the need of interventions to reduce indoor airborne particle concentrations and their transfer to premature infants with underdeveloped immune systems, even though protocols for visitors and cleaning are well-established.MORGADO GAMERO, WENDY BEATRIZ-will be generated-orcid-0000-0003-2394-2589-600Mendoza Hernandez, MarthaCastillo Ramirez, MargaritaMEDINA ALTAHONA, JHORMA JOSE-will be generated-orcid-0000-0002-3683-6905-600La Hoz Theuer, Stephanie-will be generated-orcid-0000-0001-5606-655X-600Posso Mendoza, HeidyParody, AlexanderTeixeira, Elba C.Agudelo-Castañeda, Dayana Milena-will be generated-orcid-0000-0002-6589-6835-600engInternational Journal of Environmental Research and Public Healthhttps://doi.org/10.3390/ijerph161833401. Gao, M.; Yan, X.; Qiu, T.; Han, M.; Wang, X. Variation of correlations between factors and culturable airborne bacteria and fungi. Atmos. Environ. 2016, 128, 10–19. [CrossRef] 2. 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