Reversible cognitive impairment and parkinsonism with leukoencephalopathy due to cranial dural arteriovenous fistula

Parkinsonism and rapid cognitive impairment may have many causes, but only a few have specific treatment. Cra-nial dural arteriovenous fistula (DAVF) represents 10%-15% of intracranial arteriovenous malformations. Clini-cal manifestations depend on location and venous drainage. It is common the pres...

Full description

Autores:
Laran Sánchez, Melanie
Dossi, Daiana E.
AMERISO, SEBASTIAN FRANCISCO
Tipo de recurso:
Article of journal
Fecha de publicación:
2022
Institución:
Corporación Universidad de la Costa
Repositorio:
REDICUC - Repositorio CUC
Idioma:
eng
OAI Identifier:
oai:repositorio.cuc.edu.co:11323/9723
Acceso en línea:
https://hdl.handle.net/11323/9723
https://repositorio.cuc.edu.co/
Palabra clave:
Cognitive impairment
Parkinsonism
Leukoencephalopathy
Cranial dural arteriovenous fistula
Deterioro cognitivo
Parkinsonismo
Leucoencefalopatía
Fistula arteriovenosa dural intracraneal
Rights
openAccess
License
Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)
Description
Summary:Parkinsonism and rapid cognitive impairment may have many causes, but only a few have specific treatment. Cra-nial dural arteriovenous fistula (DAVF) represents 10%-15% of intracranial arteriovenous malformations. Clini-cal manifestations depend on location and venous drainage. It is common the presence of pulsatile tinnitus, bruits and headache or headache and papilledema. Progressive cognitive decline is an unusual presentation due to bilateral thalamic edema or cortical venous hypertension. Endovascular or surgical treatment can reverse disease symptoms.We present a 74-year old man with rapidly progressive cognitive impairment and parkinsonism and a subsequent diagnosis of dural arteriovenous fistula (DAVF). Brain MRI revealed diffuse leukoencephalopathy probably attributable to elevated venous pressure. He was treated with partial embolization with Onix and left transverse sinus angioplasty. Following the procedure, there was a substantial reduction of venous pressure signs and remarkable clinical and imaging improvement, persisting at two years follow-up. This case represents an unusual presentation of DAVF. It is important to suspect the di-agnosis of DAVF in cases with rapidly evolving cognitive impairment, parkinsonism and leukoencephalopathy as it can be reversible with early treatment.