Analyzing the biochemistry of saliva: flow, total protein, amylase enzymatic activity, and their interconnections
This study examines the biochemical profile of saliva, focusing on flow rate, total protein concentration, and the enzymatic activities of amylase and catalase. The study aims to explore the correlations between these parameters and their response to physiological stress induced by physical activity...
- Autores:
-
Parraca, Jose A.
Rubio Zarapuz, Alejandro
Tornero Aguilera, José Francisco
Clemente-Suárez, Vicente Javier
Tomas Carus, Pablo
Rodrigues Costa, Ana
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2025
- Institución:
- Corporación Universidad de la Costa
- Repositorio:
- REDICUC - Repositorio CUC
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.cuc.edu.co:11323/14157
- Acceso en línea:
- https://hdl.handle.net/11323/14157
https://repositorio.cuc.edu.co/
- Palabra clave:
- Non-invasive biomarker
Physical activity
Protein concentration
Amylase activity
Saliva biochemistry
- Rights
- openAccess
- License
- Atribución 4.0 Internacional (CC BY 4.0)
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Analyzing the biochemistry of saliva: flow, total protein, amylase enzymatic activity, and their interconnections |
| title |
Analyzing the biochemistry of saliva: flow, total protein, amylase enzymatic activity, and their interconnections |
| spellingShingle |
Analyzing the biochemistry of saliva: flow, total protein, amylase enzymatic activity, and their interconnections Non-invasive biomarker Physical activity Protein concentration Amylase activity Saliva biochemistry |
| title_short |
Analyzing the biochemistry of saliva: flow, total protein, amylase enzymatic activity, and their interconnections |
| title_full |
Analyzing the biochemistry of saliva: flow, total protein, amylase enzymatic activity, and their interconnections |
| title_fullStr |
Analyzing the biochemistry of saliva: flow, total protein, amylase enzymatic activity, and their interconnections |
| title_full_unstemmed |
Analyzing the biochemistry of saliva: flow, total protein, amylase enzymatic activity, and their interconnections |
| title_sort |
Analyzing the biochemistry of saliva: flow, total protein, amylase enzymatic activity, and their interconnections |
| dc.creator.fl_str_mv |
Parraca, Jose A. Rubio Zarapuz, Alejandro Tornero Aguilera, José Francisco Clemente-Suárez, Vicente Javier Tomas Carus, Pablo Rodrigues Costa, Ana |
| dc.contributor.author.none.fl_str_mv |
Parraca, Jose A. Rubio Zarapuz, Alejandro Tornero Aguilera, José Francisco Clemente-Suárez, Vicente Javier Tomas Carus, Pablo Rodrigues Costa, Ana |
| dc.subject.proposal.eng.fl_str_mv |
Non-invasive biomarker Physical activity Protein concentration Amylase activity Saliva biochemistry |
| topic |
Non-invasive biomarker Physical activity Protein concentration Amylase activity Saliva biochemistry |
| description |
This study examines the biochemical profile of saliva, focusing on flow rate, total protein concentration, and the enzymatic activities of amylase and catalase. The study aims to explore the correlations between these parameters and their response to physiological stress induced by physical activity, providing insights into saliva’s diagnostic potential. Thirty-one participants were recruited, and saliva samples were collected before and after a structured physical activity session. Biochemical parameters were analyzed using established protocols to assess changes induced by exercise. Significant positive correlations were observed between protein concentration and amylase activity, particularly in post-exercise conditions. No significant correlations were found between the salivary flow and enzyme activities. Catalase activity displayed a weaker association with protein levels. These findings suggest that saliva can be a non-invasive biomarker for systemic health and stress responses. The study highlights the diagnostic utility of saliva and underscores the need for further investigations in younger and healthier populations to broaden the applicability of these results |
| publishDate |
2025 |
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2025-04-25T16:44:51Z |
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2025-04-25T16:44:51Z |
| dc.date.issued.none.fl_str_mv |
2025-01-19 |
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Artículo de revista |
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Parraca, J. A., Rubio-Zarapuz, A., Tornero-Aguilera, J. F., Clemente-Suárez, V. J., Tomas-Carus, P., & Costa, A. R. (2025). Analyzing the Biochemistry of Saliva: Flow, Total Protein, Amylase Enzymatic Activity, and Their Interconnections. International Journal of Molecular Sciences, 26(3), 1164. https://doi.org/10.3390/ijms26031164 |
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1422-0067 |
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https://hdl.handle.net/11323/14157 |
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10.3390/ijms26031164 |
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1661-6596 |
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Corporación Universidad de la Costa |
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REDICUC - Repositorio CUC |
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https://repositorio.cuc.edu.co/ |
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Parraca, J. A., Rubio-Zarapuz, A., Tornero-Aguilera, J. F., Clemente-Suárez, V. J., Tomas-Carus, P., & Costa, A. R. (2025). Analyzing the Biochemistry of Saliva: Flow, Total Protein, Amylase Enzymatic Activity, and Their Interconnections. International Journal of Molecular Sciences, 26(3), 1164. https://doi.org/10.3390/ijms26031164 1422-0067 10.3390/ijms26031164 1661-6596 Corporación Universidad de la Costa REDICUC - Repositorio CUC |
| url |
https://hdl.handle.net/11323/14157 https://repositorio.cuc.edu.co/ |
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eng |
| language |
eng |
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International Journal of Molecular Sciences |
| dc.relation.references.none.fl_str_mv |
Llena-Puy, C. The Rôle of Saliva in Maintaining Oral Health and as an Aid to Diagnosis. Med. Oral Patol. Oral Cirugía Bucal 2006, 11, 449–455 Dodds, M.; Roland, S.; Edgar, M.; Thornhill, M. Saliva A Review of Its Role in Maintaining Oral Health and Preventing Dental Disease. BDJ Team 2015, 2, 15123 Liao, C.; Chen, X.; Fu, Y. Salivary Analysis: An Emerging Paradigm for Non-invasive Healthcare Diagnosis and Monitoring. Interdiscip. Med. 2023, 1, e20230009 Khurshid, Z.; Jameela, A.H.; Rabia, S.K.; Zafar, M.S.; Altaf, M.; Najeeb, S. Human Saliva and Its Role in Oral and Systemic Health. J. Pak. Dent. Assoc. 2016, 25, 170–174 Van’T Hof, W.; Veerman, E.C.I.; Amerongen, A.V.N.; Ligtenberg, A.J.M. Antimicrobial Defense Systems in Saliva. Monogr. Oral Sci. 2014, 24, 40–51 Pappa, E.; Vougas, K.; Zoidakis, J.; Vastardis, H. Proteomic Advances in Salivary Diagnostics. Biochim. Et Biophys. Acta-Proteins Proteom. 2020, 1868, 140494 Kumar, P.; Gupta, S.; Das, B.C. Saliva as a Potential Non-Invasive Liquid Biopsy for Early and Easy Diagnosis/Prognosis of Head and Neck Cancer. Transl. Oncol. 2024, 40, 101827 Cižmárová, B.; Tomeˇcková, V.; Hubková, B.; Hurajtová, A.; Ohlasová, J.; Birková, A. Salivary Redox Homeostasis in Human ˇ Health and Disease. Int. J. Mol. Sci. 2022, 23, 10076 Lynge Pedersen, A.M.; Belstrøm, D. The Role of Natural Salivary Defences in Maintaining a Healthy Oral Microbiota. J. Dent. 2019, 80, S3–S12 Thoma, M.V.; Kirschbaum, C.; Wolf, J.M.; Rohleder, N. Acute Stress Responses in Salivary Alpha-Amylase Predict Increases of Plasma Norepinephrine. Biol. Psychol. 2012, 91, 342–348 Rubio-Zarapuz, A.; Apolo-Arenas, M.D.; Tomas-Carus, P.; Tornero-Aguilera, J.F.; Clemente-Suárez, V.J.; Parraca, J.A. Comparative Analysis of Psychophysiological Responses in Fibromyalgia Patients: Evaluating Neuromodulation Alone, Neuromodulation Combined with Virtual Reality, and Exercise Interventions. Medicina 2024, 60, 404 Siqueira, W.L.; Dawes, C. The Salivary Proteome: Challenges and Perspectives. Proteom. Clin. Appl. 2011, 5, 575–579 Lamy, E.; Simões, C.; Rodrigues, L.; Costa, A.R.; Vitorino, R.; Amado, F.; Antunes, C.; do Carmo, I. Changes in the Salivary Protein Profile of Morbidly Obese Women Either Previously Subjected to Bariatric Surgery or Not. J. Physiol. Biochem. 2015, 71, 691–702 Bradford, M.M. A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding. Anal. Biochem. 1976, 72, 248–254 Rodrigues, L.; Mouta, R.; Costa, A.R.; Pereira, A.; Capela E Silva, F.; Amado, F.; Antunes, C.M.; Lamy, E. Effects of High Fat Diet on Salivary α-Amylase, Serum Parameters and Food Consumption in Rats. Arch. Oral Biol. 2015, 60, 854–862 Aebi, H. [13] Catalase In Vitro. Methods Enzymol. 1984, 105, 121–126 Pérez-Ros, P.; Navarro-Flores, E.; Julián-Rochina, I.; Martínez-Arnau, F.M.; Cauli, O. Changes in Salivary Amylase and Glucose in Diabetes: A Scoping Review. Diagnostics 2021, 11, 453 Al-Bedak, O.A.H.; Sakr, R.S.; AL-Kolaibe, A.M. The Microbial Amylases: An Overview with Practical Consequences and Applications. J. Microbiol. Exp. 2022, 10, 130–134 Obayashi, K. Salivary Mental Stress Proteins. Clin. Chim. Acta 2013, 425, 196–201 Peyrot des Gachons, C.; Breslin, P.A.S. Salivary Amylase: Digestion and Metabolic Syndrome. Curr. Diabetes Rep. 2016, 16, 1–7 |
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© 2025 The authors |
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Atribución 4.0 Internacional (CC BY 4.0) |
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11 páginas |
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Switzerland |
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Multidisciplinary Digital Publishing Institute (MDPI) |
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Atribución 4.0 Internacional (CC BY 4.0)© 2025 The authorshttps://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Parraca, Jose A.Rubio Zarapuz, AlejandroTornero Aguilera, José FranciscoClemente-Suárez, Vicente Javiervirtual::1131-1Tomas Carus, PabloRodrigues Costa, Ana2025-04-25T16:44:51Z2025-04-25T16:44:51Z2025-01-19Parraca, J. A., Rubio-Zarapuz, A., Tornero-Aguilera, J. F., Clemente-Suárez, V. J., Tomas-Carus, P., & Costa, A. R. (2025). Analyzing the Biochemistry of Saliva: Flow, Total Protein, Amylase Enzymatic Activity, and Their Interconnections. International Journal of Molecular Sciences, 26(3), 1164. https://doi.org/10.3390/ijms260311641422-0067https://hdl.handle.net/11323/1415710.3390/ijms260311641661-6596Corporación Universidad de la CostaREDICUC - Repositorio CUChttps://repositorio.cuc.edu.co/This study examines the biochemical profile of saliva, focusing on flow rate, total protein concentration, and the enzymatic activities of amylase and catalase. The study aims to explore the correlations between these parameters and their response to physiological stress induced by physical activity, providing insights into saliva’s diagnostic potential. Thirty-one participants were recruited, and saliva samples were collected before and after a structured physical activity session. Biochemical parameters were analyzed using established protocols to assess changes induced by exercise. Significant positive correlations were observed between protein concentration and amylase activity, particularly in post-exercise conditions. No significant correlations were found between the salivary flow and enzyme activities. Catalase activity displayed a weaker association with protein levels. These findings suggest that saliva can be a non-invasive biomarker for systemic health and stress responses. The study highlights the diagnostic utility of saliva and underscores the need for further investigations in younger and healthier populations to broaden the applicability of these results11 páginasapplication/pdfengMultidisciplinary Digital Publishing Institute (MDPI)Switzerlandhttps://www.mdpi.com/1422-0067/26/3/1164Analyzing the biochemistry of saliva: flow, total protein, amylase enzymatic activity, and their interconnectionsArtículo de revistahttp://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85International Journal of Molecular SciencesLlena-Puy, C. The Rôle of Saliva in Maintaining Oral Health and as an Aid to Diagnosis. Med. Oral Patol. Oral Cirugía Bucal 2006, 11, 449–455Dodds, M.; Roland, S.; Edgar, M.; Thornhill, M. Saliva A Review of Its Role in Maintaining Oral Health and Preventing Dental Disease. BDJ Team 2015, 2, 15123Liao, C.; Chen, X.; Fu, Y. Salivary Analysis: An Emerging Paradigm for Non-invasive Healthcare Diagnosis and Monitoring. Interdiscip. Med. 2023, 1, e20230009Khurshid, Z.; Jameela, A.H.; Rabia, S.K.; Zafar, M.S.; Altaf, M.; Najeeb, S. Human Saliva and Its Role in Oral and Systemic Health. J. Pak. Dent. Assoc. 2016, 25, 170–174Van’T Hof, W.; Veerman, E.C.I.; Amerongen, A.V.N.; Ligtenberg, A.J.M. Antimicrobial Defense Systems in Saliva. Monogr. Oral Sci. 2014, 24, 40–51Pappa, E.; Vougas, K.; Zoidakis, J.; Vastardis, H. Proteomic Advances in Salivary Diagnostics. Biochim. Et Biophys. Acta-Proteins Proteom. 2020, 1868, 140494Kumar, P.; Gupta, S.; Das, B.C. Saliva as a Potential Non-Invasive Liquid Biopsy for Early and Easy Diagnosis/Prognosis of Head and Neck Cancer. Transl. Oncol. 2024, 40, 101827Cižmárová, B.; Tomeˇcková, V.; Hubková, B.; Hurajtová, A.; Ohlasová, J.; Birková, A. Salivary Redox Homeostasis in Human ˇ Health and Disease. Int. J. Mol. Sci. 2022, 23, 10076Lynge Pedersen, A.M.; Belstrøm, D. The Role of Natural Salivary Defences in Maintaining a Healthy Oral Microbiota. J. Dent. 2019, 80, S3–S12Thoma, M.V.; Kirschbaum, C.; Wolf, J.M.; Rohleder, N. Acute Stress Responses in Salivary Alpha-Amylase Predict Increases of Plasma Norepinephrine. Biol. Psychol. 2012, 91, 342–348Rubio-Zarapuz, A.; Apolo-Arenas, M.D.; Tomas-Carus, P.; Tornero-Aguilera, J.F.; Clemente-Suárez, V.J.; Parraca, J.A. Comparative Analysis of Psychophysiological Responses in Fibromyalgia Patients: Evaluating Neuromodulation Alone, Neuromodulation Combined with Virtual Reality, and Exercise Interventions. Medicina 2024, 60, 404Siqueira, W.L.; Dawes, C. The Salivary Proteome: Challenges and Perspectives. Proteom. Clin. Appl. 2011, 5, 575–579Lamy, E.; Simões, C.; Rodrigues, L.; Costa, A.R.; Vitorino, R.; Amado, F.; Antunes, C.; do Carmo, I. Changes in the Salivary Protein Profile of Morbidly Obese Women Either Previously Subjected to Bariatric Surgery or Not. J. Physiol. Biochem. 2015, 71, 691–702Bradford, M.M. A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding. Anal. Biochem. 1976, 72, 248–254Rodrigues, L.; Mouta, R.; Costa, A.R.; Pereira, A.; Capela E Silva, F.; Amado, F.; Antunes, C.M.; Lamy, E. Effects of High Fat Diet on Salivary α-Amylase, Serum Parameters and Food Consumption in Rats. Arch. Oral Biol. 2015, 60, 854–862Aebi, H. [13] Catalase In Vitro. Methods Enzymol. 1984, 105, 121–126Pérez-Ros, P.; Navarro-Flores, E.; Julián-Rochina, I.; Martínez-Arnau, F.M.; Cauli, O. Changes in Salivary Amylase and Glucose in Diabetes: A Scoping Review. Diagnostics 2021, 11, 453Al-Bedak, O.A.H.; Sakr, R.S.; AL-Kolaibe, A.M. The Microbial Amylases: An Overview with Practical Consequences and Applications. J. Microbiol. Exp. 2022, 10, 130–134Obayashi, K. Salivary Mental Stress Proteins. Clin. Chim. Acta 2013, 425, 196–201Peyrot des Gachons, C.; Breslin, P.A.S. Salivary Amylase: Digestion and Metabolic Syndrome. Curr. 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ara ejercer estos derechos sobre la Obra tal y como se indica a continuación:</p>
    <ol type="a">
      <li>Reproducir la Obra, incorporar la Obra en una o más Obras Colectivas, y reproducir la Obra incorporada en las Obras Colectivas.</li>
      <li>Distribuir copias o fonogramas de las Obras, exhibirlas públicamente, ejecutarlas públicamente y/o ponerlas a disposición pública, incluyéndolas como incorporadas en Obras Colectivas, según corresponda.</li>
      <li>Distribuir copias de las Obras Derivadas que se generen, exhibirlas públicamente, ejecutarlas públicamente y/o ponerlas a disposición pública.</li>
    </ol>
    <p>Los derechos mencionados anteriormente pueden ser ejercidos en todos los medios y formatos, actualmente conocidos o que se inventen en el futuro. Los derechos antes mencionados incluyen el derecho a realizar dichas modificaciones en la medida que sean técnicamente necesarias para ejercer los derechos en otro medio o formatos, pero de otra manera usted no está autorizado para realizar obras derivadas. Todos los derechos no otorgados expresamente por el Licenciante quedan por este medio reservados, incluyendo pero sin limitarse a aquellos que se mencionan en las secciones 4(d) y 4(e).</p>
  </li>
  <br/>
  <li>
    Restricciones.
    <p>La licencia otorgada en la anterior Sección 3 está expresamente sujeta y limitada por las siguientes restricciones:</p>
    <ol type="a">
      <li>Usted puede distribuir, exhibir públicamente, ejecutar públicamente, o poner a disposición pública la Obra sólo bajo las condiciones de esta Licencia, y Usted debe incluir una copia de esta licencia o del Identificador Universal de Recursos de la misma con cada copia de la Obra que distribuya, exhiba públicamente, ejecute públicamente o ponga a disposición pública. No es posible ofrecer o imponer ninguna condición sobre la Obra que altere o limite las condiciones de esta Licencia o el ejercicio de los derechos de los destinatarios otorgados en este documento. No es posible sublicenciar la Obra. Usted debe mantener intactos todos los avisos que hagan referencia a esta Licencia y a la cláusula de limitación de garantías. Usted no puede distribuir, exhibir públicamente, ejecutar públicamente, o poner a disposición pública la Obra con alguna medida tecnológica que controle el acceso o la utilización de ella de una forma que sea inconsistente con las condiciones de esta Licencia. Lo anterior se aplica a la Obra incorporada a una Obra Colectiva, pero esto no exige que la Obra Colectiva aparte de la obra misma quede sujeta a las condiciones de esta Licencia. Si Usted crea una Obra Colectiva, previo aviso de cualquier Licenciante debe, en la medida de lo posible, eliminar de la Obra Colectiva cualquier referencia a dicho Licenciante o al Autor Original, según lo solicitado por el Licenciante y conforme lo exige la cláusula 4(c).</li>
      <li>Usted no puede ejercer ninguno de los derechos que le han sido otorgados en la Sección 3 precedente de modo que estén principalmente destinados o directamente dirigidos a conseguir un provecho comercial o una compensación monetaria privada. El intercambio de la Obra por otras obras protegidas por derechos de autor, ya sea a través de un sistema para compartir archivos digitales (digital file-sharing) o de cualquier otra manera no será considerado como estar destinado principalmente o dirigido directamente a conseguir un provecho comercial o una compensación monetaria privada, siempre que no se realice un pago mediante una compensación monetaria en relación con el intercambio de obras protegidas por el derecho de autor.</li>
      <li>Si usted distribuye, exhibe públicamente, ejecuta públicamente o ejecuta públicamente en forma digital la Obra o cualquier Obra Derivada u Obra Colectiva, Usted debe mantener intacta toda la información de derecho de autor de la Obra y proporcionar, de forma razonable según el medio o manera que Usted esté utilizando: (i) el nombre del Autor Original si está provisto (o seudónimo, si fuere aplicable), y/o (ii) el nombre de la parte o las partes que el Autor Original y/o el Licenciante hubieren designado para la atribución (v.g., un instituto patrocinador, editorial, publicación) en la información de los derechos de autor del Licenciante, términos de servicios o de otras formas razonables; el título de la Obra si está provisto; en la medida de lo razonablemente factible y, si está provisto, el Identificador Uniforme de Recursos (Uniform Resource Identifier) que el Licenciante especifica para ser asociado con la Obra, salvo que tal URI no se refiera a la nota sobre los derechos de autor o a la información sobre el licenciamiento de la Obra; y en el caso de una Obra Derivada, atribuir el crédito identificando el uso de la Obra en la Obra Derivada (v.g., "Traducción Francesa de la Obra del Autor Original," o "Guión Cinematográfico basado en la Obra original del Autor Original"). Tal crédito puede ser implementado de cualquier forma razonable; en el caso, sin embargo, de Obras Derivadas u Obras Colectivas, tal crédito aparecerá, como mínimo, donde aparece el crédito de cualquier otro autor comparable y de una manera, al menos, tan destacada como el crédito de otro autor comparable.</li>
      <li>
        Para evitar toda confusión, el Licenciante aclara que, cuando la obra es una composición musical:
        <ol type="i">
          <li>Regalías por interpretación y ejecución bajo licencias generales. El Licenciante se reserva el derecho exclusivo de autorizar la ejecución pública o la ejecución pública digital de la obra y de recolectar, sea individualmente o a través de una sociedad de gestión colectiva de derechos de autor y derechos conexos (por ejemplo, SAYCO), las regalías por la ejecución pública o por la ejecución pública digital de la obra (por ejemplo Webcast) licenciada bajo licencias generales, si la interpretación o ejecución de la obra está primordialmente orientada por o dirigida a la obtención de una ventaja comercial o una compensación monetaria privada.</li>
          <li>Regalías por Fonogramas. El Licenciante se reserva el derecho exclusivo de recolectar, individualmente o a través de una sociedad de gestión colectiva de derechos de autor y derechos conexos (por ejemplo, los consagrados por la SAYCO), una agencia de derechos musicales o algún agente designado, las regalías por cualquier fonograma que Usted cree a partir de la obra (“versión cover”) y distribuya, en los términos del régimen de derechos de autor, si la creación o distribución de esa versión cover está primordialmente destinada o dirigida a obtener una ventaja comercial o una compensación monetaria privada.</li>
        </ol>
      </li>
      <li>Gestión de Derechos de Autor sobre Interpretaciones y Ejecuciones Digitales (WebCasting). Para evitar toda confusión, el Licenciante aclara que, cuando la obra sea un fonograma, el Licenciante se reserva el derecho exclusivo de autorizar la ejecución pública digital de la obra (por ejemplo, webcast) y de recolectar, individualmente o a través de una sociedad de gestión colectiva de derechos de autor y derechos conexos (por ejemplo, ACINPRO), las regalías por la ejecución pública digital de la obra (por ejemplo, webcast), sujeta a las disposiciones aplicables del régimen de Derecho de Autor, si esta ejecución pública digital está primordialmente dirigida a obtener una ventaja comercial o una compensación monetaria privada.</li>
    </ol>
  </li>
  <br/>
  <li>
    Representaciones, Garantías y Limitaciones de Responsabilidad.
    <p>A MENOS QUE LAS PARTES LO ACORDARAN DE OTRA FORMA POR ESCRITO, EL LICENCIANTE OFRECE LA OBRA (EN EL ESTADO EN EL QUE SE ENCUENTRA) “TAL CUAL”, SIN BRINDAR GARANTÍAS DE CLASE ALGUNA RESPECTO DE LA OBRA, YA SEA EXPRESA, IMPLÍCITA, LEGAL O CUALQUIERA OTRA, INCLUYENDO, SIN LIMITARSE A ELLAS, GARANTÍAS DE TITULARIDAD, COMERCIABILIDAD, ADAPTABILIDAD O ADECUACIÓN A PROPÓSITO DETERMINADO, AUSENCIA DE INFRACCIÓN, DE AUSENCIA DE DEFECTOS LATENTES O DE OTRO TIPO, O LA PRESENCIA O AUSENCIA DE ERRORES, SEAN O NO DESCUBRIBLES (PUEDAN O NO SER ESTOS DESCUBIERTOS). ALGUNAS JURISDICCIONES NO PERMITEN LA EXCLUSIÓN DE GARANTÍAS IMPLÍCITAS, EN CUYO CASO ESTA EXCLUSIÓN PUEDE NO APLICARSE A USTED.</p>
  </li>
  <br/>
  <li>
    Limitación de responsabilidad.
    <p>A MENOS QUE LO EXIJA EXPRESAMENTE LA LEY APLICABLE, EL LICENCIANTE NO SERÁ RESPONSABLE ANTE USTED POR DAÑO ALGUNO, SEA POR RESPONSABILIDAD EXTRACONTRACTUAL, PRECONTRACTUAL O CONTRACTUAL, OBJETIVA O SUBJETIVA, SE TRATE DE DAÑOS MORALES O PATRIMONIALES, DIRECTOS O INDIRECTOS, PREVISTOS O IMPREVISTOS PRODUCIDOS POR EL USO DE ESTA LICENCIA O DE LA OBRA, AUN CUANDO EL LICENCIANTE HAYA SIDO ADVERTIDO DE LA POSIBILIDAD DE DICHOS DAÑOS. ALGUNAS LEYES NO PERMITEN LA EXCLUSIÓN DE CIERTA RESPONSABILIDAD, EN CUYO CASO ESTA EXCLUSIÓN PUEDE NO APLICARSE A USTED.</p>
  </li>
  <br/>
  <li>
    Término.
    <ol type="a">
      <li>Esta Licencia y los derechos otorgados en virtud de ella terminarán automáticamente si Usted infringe alguna condición establecida en ella. Sin embargo, los individuos o entidades que han recibido Obras Derivadas o Colectivas de Usted de conformidad con esta Licencia, no verán terminadas sus licencias, siempre que estos individuos o entidades sigan cumpliendo íntegramente las condiciones de estas licencias. Las Secciones 1, 2, 5, 6, 7, y 8 subsistirán a cualquier terminación de esta Licencia.</li>
      <li>Sujeta a las condiciones y términos anteriores, la licencia otorgada aquí es perpetua (durante el período de vigencia de los derechos de autor de la obra). No obstante lo anterior, el Licenciante se reserva el derecho a publicar y/o estrenar la Obra bajo condiciones de licencia diferentes o a dejar de distribuirla en los términos de esta Licencia en cualquier momento; en el entendido, sin embargo, que esa elección no servirá para revocar esta licencia o que deba ser otorgada , bajo los términos de esta licencia), y esta licencia continuará en pleno vigor y efecto a menos que sea terminada como se expresa atrás. La Licencia revocada continuará siendo plenamente vigente y efectiva si no se le da término en las condiciones indicadas anteriormente.</li>
    </ol>
  </li>
  <br/>
  <li>
    Varios.
    <ol type="a">
      <li>Cada vez que Usted distribuya o ponga a disposición pública la Obra o una Obra Colectiva, el Licenciante ofrecerá al destinatario una licencia en los mismos términos y condiciones que la licencia otorgada a Usted bajo esta Licencia.</li>
      <li>Si alguna disposición de esta Licencia resulta invalidada o no exigible, según la legislación vigente, esto no afectará ni la validez ni la aplicabilidad del resto de condiciones de esta Licencia y, sin acción adicional por parte de los sujetos de este acuerdo, aquélla se entenderá reformada lo mínimo necesario para hacer que dicha disposición sea válida y exigible.</li>
      <li>Ningún término o disposición de esta Licencia se estimará renunciada y ninguna violación de ella será consentida a menos que esa renuncia o consentimiento sea otorgado por escrito y firmado por la parte que renuncie o consienta.</li>
      <li>Esta Licencia refleja el acuerdo pleno entre las partes respecto a la Obra aquí licenciada. No hay arreglos, acuerdos o declaraciones respecto a la Obra que no estén especificados en este documento. El Licenciante no se verá limitado por ninguna disposición adicional que pueda surgir en alguna comunicación emanada de Usted. Esta Licencia no puede ser modificada sin el consentimiento mutuo por escrito del Licenciante y Usted.</li>
    </ol>
  </li>
  <br/>
</ol>
 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