Cognitive alterations in patients with alterations in sleep architecture in a court of Colombian patients

Introduction: Increasing evidence suggests that sleep disorders precede the onset of Alzheimer's disease by years, which is why it has been proposed that patients with alterations in sleep architecture have some degree of cognitive impairment (subjective complaint of memory or cognitive level impairment). In neurological clinical practice, we observe that sleep studies ordered to rule out OSAHS generally do not show severe alterations in this aspect, but they do show alterations in sleep architecture, mainly low sleep efficiency and N3 sleep proportion. Patients with memory problems may have alterations in the structure of sleep, however it remains unclear if having an affectation in the organization of sleep affects the cognition of the subjects. With this work we want to describe the results of cognitive tests in patients with results in sleep architecture. Materials and methods: Descriptive cross-sectional study, where 160 polysomnographies were reviewed, 68 patients met the inclusion criteria and 31 agreed to the Montreal Cognitive Assessment (MOCA) cognitive test to detect level cognitive impairment and the Hopkins test. for memory evaluation, they cannot have moderate or severe sleep apnea syndrome and cannot be taking medications that cause the sleep-wake cycle. Results: 77% presented the MOCA test below the normal values validated for the Colombian population, without finding significant differences between patients without OSAHS and with mild OSAHS, with delayed recall being the most affected domain. Conclusions: 1. 77% of the patients included in the study presented MOCA test values below the normal values validated for the Colombian population. 2. There were no significant differences between patients with AHI <5 and AHI 5 - 15. 3. The Hopkins test was used in the majority of patients with alterations in the architecture of sleep. 4. Alterations in sleep architecture could be a factor associated with cognitive disorders and thus could motivate a complete neuropsychological assessment. Acknowledgements: To my mother Alma Luz, my teachers and patients who inspire us to study every day

• Autores: Diaz Rodríguez, María Cecilia; Camargo, Loida; Rojas, A.; Castillo-Tamara, Edgard ELIUD; Tavera, L; López, Norman; Ramos, E.; Porto, María F.
• Tipo de recurso: Article of investigation
• Fecha de publicación: 2022
• Institución: Corporación Universidad de la Costa
• Repositorio: REDICUC - Repositorio CUC
• Idioma: eng
• OAI Identifier: oai:repositorio.cuc.edu.co:11323/10727
• Acceso en línea: https://hdl.handle.net/11323/10727; https://repositorio.cuc.edu.co/
• Palabra clave: Alterations in sleep; Sleep architecture; Colombia
• Rights: openAccess
• License: Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)