New insights on enzyme stabilization for industrial biocatalysis
Due to their versatility and ability to provide tunable chemo-, regio-, and enantio-selectivitites, enzyme-mediated transformations offer an effective and eco-friendly alternative to the traditional multistep chemical synthesis methods, which often require organic solvents, hazardous reagents, and t...
- Autores:
-
Fernández-Lucas, Jesús
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2021
- Institución:
- Corporación Universidad de la Costa
- Repositorio:
- REDICUC - Repositorio CUC
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.cuc.edu.co:11323/9062
- Acceso en línea:
- https://hdl.handle.net/11323/9062
https://doi.org/10.1021/acssuschemeng.1c06785
https://repositorio.cuc.edu.co/
- Palabra clave:
- Peptides and proteins
Nanoparticles
Immobilization
Post-translational modification
Stability
- Rights
- embargoedAccess
- License
- Copyright © Published 2021 by American Chemical Society
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dc.title.eng.fl_str_mv |
New insights on enzyme stabilization for industrial biocatalysis |
title |
New insights on enzyme stabilization for industrial biocatalysis |
spellingShingle |
New insights on enzyme stabilization for industrial biocatalysis Peptides and proteins Nanoparticles Immobilization Post-translational modification Stability |
title_short |
New insights on enzyme stabilization for industrial biocatalysis |
title_full |
New insights on enzyme stabilization for industrial biocatalysis |
title_fullStr |
New insights on enzyme stabilization for industrial biocatalysis |
title_full_unstemmed |
New insights on enzyme stabilization for industrial biocatalysis |
title_sort |
New insights on enzyme stabilization for industrial biocatalysis |
dc.creator.fl_str_mv |
Fernández-Lucas, Jesús |
dc.contributor.author.spa.fl_str_mv |
Fernández-Lucas, Jesús |
dc.subject.proposal.eng.fl_str_mv |
Peptides and proteins Nanoparticles Immobilization Post-translational modification Stability |
topic |
Peptides and proteins Nanoparticles Immobilization Post-translational modification Stability |
description |
Due to their versatility and ability to provide tunable chemo-, regio-, and enantio-selectivitites, enzyme-mediated transformations offer an effective and eco-friendly alternative to the traditional multistep chemical synthesis methods, which often require organic solvents, hazardous reagents, and tedious purification processes. While enzymes provide high catalytic and specific activity at mild conditions, several operational drawbacks hamper the application of enzymes as industrial biocatalysts. These include poor performance when confronting non-natural substrates, inhibition by certain components in the reaction media, short lifetime, lack of reusability, and recovery postreaction. Among these, achieving enzyme stabilization is most challenging from a practical standpoint. |
publishDate |
2021 |
dc.date.issued.none.fl_str_mv |
2021 |
dc.date.accessioned.none.fl_str_mv |
2022-03-10T19:03:49Z |
dc.date.available.none.fl_str_mv |
2022 2022-03-10T19:03:49Z |
dc.type.spa.fl_str_mv |
Artículo de revista |
dc.type.coar.fl_str_mv |
http://purl.org/coar/resource_type/c_2df8fbb1 |
dc.type.coar.spa.fl_str_mv |
http://purl.org/coar/resource_type/c_6501 |
dc.type.content.spa.fl_str_mv |
Text |
dc.type.driver.spa.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.redcol.spa.fl_str_mv |
http://purl.org/redcol/resource_type/ART |
dc.type.version.spa.fl_str_mv |
info:eu-repo/semantics/acceptedVersion |
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http://purl.org/coar/resource_type/c_6501 |
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acceptedVersion |
dc.identifier.citation.spa.fl_str_mv |
ACS Sustainable Chem. Eng. 2021, 9, 45, 15073–15074 Publication Date:November 15, 2021 https://doi.org/10.1021/acssuschemeng.1c06785 |
dc.identifier.uri.spa.fl_str_mv |
https://hdl.handle.net/11323/9062 |
dc.identifier.url.spa.fl_str_mv |
https://doi.org/10.1021/acssuschemeng.1c06785 |
dc.identifier.doi.spa.fl_str_mv |
10.1021/acssuschemeng.1c06785 |
dc.identifier.eissn.spa.fl_str_mv |
2168-0485 |
dc.identifier.instname.spa.fl_str_mv |
Corporación Universidad de la Costa |
dc.identifier.reponame.spa.fl_str_mv |
REDICUC - Repositorio CUC |
dc.identifier.repourl.spa.fl_str_mv |
https://repositorio.cuc.edu.co/ |
identifier_str_mv |
ACS Sustainable Chem. Eng. 2021, 9, 45, 15073–15074 Publication Date:November 15, 2021 https://doi.org/10.1021/acssuschemeng.1c06785 10.1021/acssuschemeng.1c06785 2168-0485 Corporación Universidad de la Costa REDICUC - Repositorio CUC |
url |
https://hdl.handle.net/11323/9062 https://doi.org/10.1021/acssuschemeng.1c06785 https://repositorio.cuc.edu.co/ |
dc.language.iso.none.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartofjournal.spa.fl_str_mv |
ACS Sustainable Chemistry and Engineering |
dc.relation.citationvolume.spa.fl_str_mv |
9 |
dc.rights.spa.fl_str_mv |
Copyright © Published 2021 by American Chemical Society Atribución-NoComercial-CompartirIgual 4.0 Internacional (CC BY-NC-SA 4.0) |
dc.rights.uri.spa.fl_str_mv |
https://creativecommons.org/licenses/by-nc-sa/4.0/ |
dc.rights.accessrights.spa.fl_str_mv |
info:eu-repo/semantics/embargoedAccess |
dc.rights.coar.spa.fl_str_mv |
http://purl.org/coar/access_right/c_f1cf |
rights_invalid_str_mv |
Copyright © Published 2021 by American Chemical Society Atribución-NoComercial-CompartirIgual 4.0 Internacional (CC BY-NC-SA 4.0) https://creativecommons.org/licenses/by-nc-sa/4.0/ http://purl.org/coar/access_right/c_f1cf |
eu_rights_str_mv |
embargoedAccess |
dc.format.extent.spa.fl_str_mv |
2 páginas |
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application/pdf |
dc.publisher.spa.fl_str_mv |
American Chemical Society |
dc.publisher.place.spa.fl_str_mv |
United States |
institution |
Corporación Universidad de la Costa |
dc.source.url.spa.fl_str_mv |
https://pubs.acs.org/doi/full/10.1021/acssuschemeng.1c06785 |
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Fernández-Lucas, Jesús2022-03-10T19:03:49Z20222022-03-10T19:03:49Z2021ACS Sustainable Chem. Eng. 2021, 9, 45, 15073–15074 Publication Date:November 15, 2021 https://doi.org/10.1021/acssuschemeng.1c06785https://hdl.handle.net/11323/9062https://doi.org/10.1021/acssuschemeng.1c0678510.1021/acssuschemeng.1c067852168-0485Corporación Universidad de la CostaREDICUC - Repositorio CUChttps://repositorio.cuc.edu.co/Due to their versatility and ability to provide tunable chemo-, regio-, and enantio-selectivitites, enzyme-mediated transformations offer an effective and eco-friendly alternative to the traditional multistep chemical synthesis methods, which often require organic solvents, hazardous reagents, and tedious purification processes. While enzymes provide high catalytic and specific activity at mild conditions, several operational drawbacks hamper the application of enzymes as industrial biocatalysts. These include poor performance when confronting non-natural substrates, inhibition by certain components in the reaction media, short lifetime, lack of reusability, and recovery postreaction. Among these, achieving enzyme stabilization is most challenging from a practical standpoint.2 páginasapplication/pdfengAmerican Chemical SocietyUnited StatesCopyright © Published 2021 by American Chemical SocietyAtribución-NoComercial-CompartirIgual 4.0 Internacional (CC BY-NC-SA 4.0)https://creativecommons.org/licenses/by-nc-sa/4.0/info:eu-repo/semantics/embargoedAccesshttp://purl.org/coar/access_right/c_f1cfNew insights on enzyme stabilization for industrial biocatalysisArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/acceptedVersionhttps://pubs.acs.org/doi/full/10.1021/acssuschemeng.1c06785ACS Sustainable Chemistry and Engineering9Peptides and proteinsNanoparticlesImmobilizationPost-translational modificationStabilityPublicationORIGINALNew Insights on Enzyme Stabilization for Industrial Biocatalysis.pdfNew Insights on Enzyme 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