Effects of coconut oil long-term supplementation in Wistar rats during metabolic syndrome - regulation of metabolic conditions involving glucose homeostasis, inflammatory signals, and oxidative stress
This study was designed to evaluate the long-term effects of Fructose (20%) feeding in rats, simulating metabolic syndrome (MetS), and the effects of coconut oil (C.O.) supplementation when administered in a MetS context. MetS is a cluster of systemic conditions that represent an increased chance of...
- Autores:
-
Mautone Gomes, Henrique
Silveira, Alexandre K.
Gasparotto, Juciano
Bortolin, Rafael Calixto
Terra, Silvia R.
Brum, Pedro O.
Gelain, Daniel
Fonseca Moreira, José C.
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2023
- Institución:
- Corporación Universidad de la Costa
- Repositorio:
- REDICUC - Repositorio CUC
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.cuc.edu.co:11323/10365
- Acceso en línea:
- https://hdl.handle.net/11323/10365
https://repositorio.cuc.edu.co/
- Palabra clave:
- Coconut oil
Glucose homeostasis
Inflammatory signals
Oxidative stress
- Rights
- embargoedAccess
- License
- Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)
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Effects of coconut oil long-term supplementation in Wistar rats during metabolic syndrome - regulation of metabolic conditions involving glucose homeostasis, inflammatory signals, and oxidative stress |
| title |
Effects of coconut oil long-term supplementation in Wistar rats during metabolic syndrome - regulation of metabolic conditions involving glucose homeostasis, inflammatory signals, and oxidative stress |
| spellingShingle |
Effects of coconut oil long-term supplementation in Wistar rats during metabolic syndrome - regulation of metabolic conditions involving glucose homeostasis, inflammatory signals, and oxidative stress Coconut oil Glucose homeostasis Inflammatory signals Oxidative stress |
| title_short |
Effects of coconut oil long-term supplementation in Wistar rats during metabolic syndrome - regulation of metabolic conditions involving glucose homeostasis, inflammatory signals, and oxidative stress |
| title_full |
Effects of coconut oil long-term supplementation in Wistar rats during metabolic syndrome - regulation of metabolic conditions involving glucose homeostasis, inflammatory signals, and oxidative stress |
| title_fullStr |
Effects of coconut oil long-term supplementation in Wistar rats during metabolic syndrome - regulation of metabolic conditions involving glucose homeostasis, inflammatory signals, and oxidative stress |
| title_full_unstemmed |
Effects of coconut oil long-term supplementation in Wistar rats during metabolic syndrome - regulation of metabolic conditions involving glucose homeostasis, inflammatory signals, and oxidative stress |
| title_sort |
Effects of coconut oil long-term supplementation in Wistar rats during metabolic syndrome - regulation of metabolic conditions involving glucose homeostasis, inflammatory signals, and oxidative stress |
| dc.creator.fl_str_mv |
Mautone Gomes, Henrique Silveira, Alexandre K. Gasparotto, Juciano Bortolin, Rafael Calixto Terra, Silvia R. Brum, Pedro O. Gelain, Daniel Fonseca Moreira, José C. |
| dc.contributor.author.none.fl_str_mv |
Mautone Gomes, Henrique Silveira, Alexandre K. Gasparotto, Juciano Bortolin, Rafael Calixto Terra, Silvia R. Brum, Pedro O. Gelain, Daniel Fonseca Moreira, José C. |
| dc.subject.proposal.eng.fl_str_mv |
Coconut oil Glucose homeostasis Inflammatory signals Oxidative stress |
| topic |
Coconut oil Glucose homeostasis Inflammatory signals Oxidative stress |
| description |
This study was designed to evaluate the long-term effects of Fructose (20%) feeding in rats, simulating metabolic syndrome (MetS), and the effects of coconut oil (C.O.) supplementation when administered in a MetS context. MetS is a cluster of systemic conditions that represent an increased chance of developing cardiovascular diseases and type 2 diabetes in the future. C.O. has been the target of media speculation, and recent studies report inconsistent results. C.O. improved glucose homeostasis and reduced fat accumulation in Fructose-fed rats while decreasing the levels of triglycerides (TGs) in the liver. C.O. supplementation also increased TGs levels and fructosamine in serum during MetS, possibly due to white adipose tissue breakdown and high fructose feeding. Pro-inflammatory cytokines IL-1β and TNF-α were also increased in rats treated with Fructose and C.O. Oxidative stress marker nitrotyrosine is increased in fructose-fed animals, and C.O. treatment did not prevent this damage. No significant changes were observed in lipoperoxidation marker 4-Hydroxynonenal; however, fructose feeding increased total conjugated dienes and caused conjugated dienes to switch their conformation from cis-trans to trans-trans, which was not prevented by C.O. treatment. Potential benefits of C.O. have been reported with inconsistent results, and indeed we observed some benefits of C.O. supplementation in aiding weight loss, fat accumulation, and improving glucose homeostasis. Nonetheless, we also demonstrated that long-term C.O. supplementation could present some problematic effects with higher risk for individuals suffering MetS, including increased TGs and fructosamine levels and conformational changes in dienes. |
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2023 |
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2023-08-08T19:02:03Z |
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2023-08-08T19:02:03Z 2024 |
| dc.date.issued.none.fl_str_mv |
2023 |
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Artículo de revista |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
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Text |
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Henrique Mautone Gomes, Alexandre K. Silveira, Juciano Gasparotto, Rafael Calixto Bortolin, Silvia R. Terra, Pedro O. Brum, Daniel P. Gelain, José C. Fonseca Moreira, Effects of coconut oil long-term supplementation in Wistar rats during metabolic syndrome - regulation of metabolic conditions involving glucose homeostasis, inflammatory signals, and oxidative stress, The Journal of Nutritional Biochemistry, Volume 114, 2023, 109272, ISSN 0955-2863, https://doi.org/10.1016/j.jnutbio.2023.109272 |
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0955-2863 |
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https://hdl.handle.net/11323/10365 |
| dc.identifier.doi.none.fl_str_mv |
10.1016/j.jnutbio.2023.109272 |
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1873-4847 |
| dc.identifier.instname.spa.fl_str_mv |
Corporación Universidad de la Costa |
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REDICUC - Repositorio CUC |
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https://repositorio.cuc.edu.co/ |
| identifier_str_mv |
Henrique Mautone Gomes, Alexandre K. Silveira, Juciano Gasparotto, Rafael Calixto Bortolin, Silvia R. Terra, Pedro O. Brum, Daniel P. Gelain, José C. Fonseca Moreira, Effects of coconut oil long-term supplementation in Wistar rats during metabolic syndrome - regulation of metabolic conditions involving glucose homeostasis, inflammatory signals, and oxidative stress, The Journal of Nutritional Biochemistry, Volume 114, 2023, 109272, ISSN 0955-2863, https://doi.org/10.1016/j.jnutbio.2023.109272 0955-2863 10.1016/j.jnutbio.2023.109272 1873-4847 Corporación Universidad de la Costa REDICUC - Repositorio CUC |
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https://hdl.handle.net/11323/10365 https://repositorio.cuc.edu.co/ |
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eng |
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eng |
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Journal of Nutritional Biochemistry |
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B Swinburn et al. Increased food energy supply is more than sufficient to explain the US epidemic of obesity Am J Clin Nutr (2009) BA Swinburn et al. The global obesity pandemic: shaped by global drivers and local environments Lancet (2011) SL Samson et al. Metabolic syndrome Endocrinol Metab Clin North Am (2014) RH Eckel et al. The metabolic syndrome Lancet (2005) I Grattagliano et al. Oxidative stress-induced risk factors associated with the metabolic syndrome: a unifying hypothesis J Nutr Biochem (2008) AM Lottenberg et al. The role of dietary fatty acids in the pathology of metabolic syndrome J Nutr Biochem (2012) K Albracht-Schulte et al. Omega-3 fatty acids in obesity and metabolic syndrome: a mechanistic update J Nutr Biochem (2018) CK Roberts et al. Oxidative stress and metabolic syndrome Life Sci (2009) CC Martins et al. Increased oxidative stress and inflammatory markers contrasting with the activation of the cholinergic anti-inflammatory pathway in patients with metabolic syndrome Clin Biochem (2021) S Kannappan et al. Suppression of hepatic oxidative events and regulation of eNOS expression in the liver by naringenin in fructose-administered rats Eur J Pharmacol (2010) AI Mohamed et al. The effect of dietary menhaden, olive, and coconut oil fed with three levels of vitamin E on plasma and liver lipids and plasma fatty acid composition in rats J Nutr Biochem (2002) V López-Salazar et al. Consumption of soybean or olive oil at recommended concentrations increased the intestinal microbiota diversity and insulin sensitivity and prevented fatty liver compared to the effects of coconut oil J Nutr Biochem (2021) MM. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal Biochem (1976) GL. Ellman Tissue sulfhydryl groups Arch Biochem Biophys (1959) RO Recknagel et al. [40]Spectrophotometric detection of lipid conjugated dienes. Oxygen radicals in biological systems (1984) SW. Vetter Glycated serum albumin and AGE receptors Adv Clin Chem (2015) N Mittman et al. Serum fructosamine versus glycosylated hemoglobin as an index of glycemic control, hospitalization, and infection in diabetic hemodialysis patients Kidney Int Suppl (2010) D Jahn et al. Animal models of NAFLD from a hepatologist's point of view Biochim Biophys Acta Mol Basis Dis (2019) P Dandona et al. Inflammation: the link between insulin resistance, obesity and diabetes Trends Immunol (2004) M Kunitomo et al. Beneficial effect of coenzyme Q10 on increased oxidative and nitrative stress and inflammation and individual metabolic components developing in a rat model of metabolic syndrome J Pharmacol Sci (2008) W-C Lee et al. Pathophysiological studies of overactive bladder and bladder motor dysfunction in a rat model of metabolic syndrome J Urol (2011) S Kagota et al. Chronic oxidative-nitrosative stress impairs coronary vasodilation in metabolic syndrome model rats Microvasc Res (2013) PK Bagul et al. Attenuation of insulin resistance, metabolic syndrome and hepatic oxidative stress by resveratrol in fructose-fed rats Pharmacol Res (2012) D Bhagya et al. Therapeutic effects of tender coconut water on oxidative stress in fructose fed insulin resistant hypertensive rats Asian Pac J Trop Med (2012) WJ Adeyemi et al. Investigation of the effects of dietary modification in experimental obesity: low dose of virgin coconut oil has a potent therapeutic value Biomed Pharmacother (2020) D Cutler et al. Why have americans become more obese? (2003) |
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114 |
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Copyright © 2023 Elsevier B.V. |
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Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0) |
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https://creativecommons.org/licenses/by-nc-nd/4.0/ |
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Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)Copyright © 2023 Elsevier B.V.https://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/embargoedAccesshttp://purl.org/coar/access_right/c_f1cfMautone Gomes, HenriqueSilveira, Alexandre K.Gasparotto, JucianoBortolin, Rafael CalixtoTerra, Silvia R.Brum, Pedro O.Gelain, DanielFonseca Moreira, José C.2023-08-08T19:02:03Z20242023-08-08T19:02:03Z2023Henrique Mautone Gomes, Alexandre K. Silveira, Juciano Gasparotto, Rafael Calixto Bortolin, Silvia R. Terra, Pedro O. Brum, Daniel P. Gelain, José C. Fonseca Moreira, Effects of coconut oil long-term supplementation in Wistar rats during metabolic syndrome - regulation of metabolic conditions involving glucose homeostasis, inflammatory signals, and oxidative stress, The Journal of Nutritional Biochemistry, Volume 114, 2023, 109272, ISSN 0955-2863, https://doi.org/10.1016/j.jnutbio.2023.1092720955-2863https://hdl.handle.net/11323/1036510.1016/j.jnutbio.2023.1092721873-4847Corporación Universidad de la CostaREDICUC - Repositorio CUChttps://repositorio.cuc.edu.co/This study was designed to evaluate the long-term effects of Fructose (20%) feeding in rats, simulating metabolic syndrome (MetS), and the effects of coconut oil (C.O.) supplementation when administered in a MetS context. MetS is a cluster of systemic conditions that represent an increased chance of developing cardiovascular diseases and type 2 diabetes in the future. C.O. has been the target of media speculation, and recent studies report inconsistent results. C.O. improved glucose homeostasis and reduced fat accumulation in Fructose-fed rats while decreasing the levels of triglycerides (TGs) in the liver. C.O. supplementation also increased TGs levels and fructosamine in serum during MetS, possibly due to white adipose tissue breakdown and high fructose feeding. Pro-inflammatory cytokines IL-1β and TNF-α were also increased in rats treated with Fructose and C.O. Oxidative stress marker nitrotyrosine is increased in fructose-fed animals, and C.O. treatment did not prevent this damage. No significant changes were observed in lipoperoxidation marker 4-Hydroxynonenal; however, fructose feeding increased total conjugated dienes and caused conjugated dienes to switch their conformation from cis-trans to trans-trans, which was not prevented by C.O. treatment. Potential benefits of C.O. have been reported with inconsistent results, and indeed we observed some benefits of C.O. supplementation in aiding weight loss, fat accumulation, and improving glucose homeostasis. Nonetheless, we also demonstrated that long-term C.O. supplementation could present some problematic effects with higher risk for individuals suffering MetS, including increased TGs and fructosamine levels and conformational changes in dienes.1 páginaapplication/pdfengElsevier Inc.United Stateshttps://www.sciencedirect.com/science/article/abs/pii/S0955286323000062Effects of coconut oil long-term supplementation in Wistar rats during metabolic syndrome - regulation of metabolic conditions involving glucose homeostasis, inflammatory signals, and oxidative stressArtículo de revistahttp://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/drafthttp://purl.org/coar/version/c_b1a7d7d4d402bcceJournal of Nutritional BiochemistryB Swinburn et al. Increased food energy supply is more than sufficient to explain the US epidemic of obesity Am J Clin Nutr (2009)BA Swinburn et al. The global obesity pandemic: shaped by global drivers and local environments Lancet (2011)SL Samson et al. Metabolic syndrome Endocrinol Metab Clin North Am (2014)RH Eckel et al. The metabolic syndrome Lancet (2005)I Grattagliano et al. Oxidative stress-induced risk factors associated with the metabolic syndrome: a unifying hypothesis J Nutr Biochem (2008)AM Lottenberg et al. The role of dietary fatty acids in the pathology of metabolic syndrome J Nutr Biochem (2012)K Albracht-Schulte et al. Omega-3 fatty acids in obesity and metabolic syndrome: a mechanistic update J Nutr Biochem (2018)CK Roberts et al. Oxidative stress and metabolic syndrome Life Sci (2009)CC Martins et al. Increased oxidative stress and inflammatory markers contrasting with the activation of the cholinergic anti-inflammatory pathway in patients with metabolic syndrome Clin Biochem (2021)S Kannappan et al. Suppression of hepatic oxidative events and regulation of eNOS expression in the liver by naringenin in fructose-administered rats Eur J Pharmacol (2010)AI Mohamed et al. The effect of dietary menhaden, olive, and coconut oil fed with three levels of vitamin E on plasma and liver lipids and plasma fatty acid composition in rats J Nutr Biochem (2002)V López-Salazar et al. Consumption of soybean or olive oil at recommended concentrations increased the intestinal microbiota diversity and insulin sensitivity and prevented fatty liver compared to the effects of coconut oil J Nutr Biochem (2021)MM. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal Biochem (1976)GL. Ellman Tissue sulfhydryl groups Arch Biochem Biophys (1959)RO Recknagel et al. [40]Spectrophotometric detection of lipid conjugated dienes. Oxygen radicals in biological systems (1984)SW. Vetter Glycated serum albumin and AGE receptors Adv Clin Chem (2015)N Mittman et al. Serum fructosamine versus glycosylated hemoglobin as an index of glycemic control, hospitalization, and infection in diabetic hemodialysis patients Kidney Int Suppl (2010)D Jahn et al. Animal models of NAFLD from a hepatologist's point of view Biochim Biophys Acta Mol Basis Dis (2019)P Dandona et al. Inflammation: the link between insulin resistance, obesity and diabetes Trends Immunol (2004)M Kunitomo et al. Beneficial effect of coenzyme Q10 on increased oxidative and nitrative stress and inflammation and individual metabolic components developing in a rat model of metabolic syndrome J Pharmacol Sci (2008)W-C Lee et al. Pathophysiological studies of overactive bladder and bladder motor dysfunction in a rat model of metabolic syndrome J Urol (2011)S Kagota et al. Chronic oxidative-nitrosative stress impairs coronary vasodilation in metabolic syndrome model rats Microvasc Res (2013)PK Bagul et al. Attenuation of insulin resistance, metabolic syndrome and hepatic oxidative stress by resveratrol in fructose-fed rats Pharmacol Res (2012)D Bhagya et al. Therapeutic effects of tender coconut water on oxidative stress in fructose fed insulin resistant hypertensive rats Asian Pac J Trop Med (2012)WJ Adeyemi et al. Investigation of the effects of dietary modification in experimental obesity: low dose of virgin coconut oil has a potent therapeutic value Biomed Pharmacother (2020)D Cutler et al. Why have americans become more obese? (2003)114Coconut oilGlucose homeostasisInflammatory signalsOxidative stressPublicationORIGINALEffects of coconut oil long-term supplementation in Wistar rats during metabolic syndrome - regulation of metabolic conditions involving glucose homeostasis, inflammatory signals, and oxidative stress.pdfEffects of coconut oil long-term supplementation in Wistar rats during metabolic syndrome - regulation of metabolic conditions involving glucose homeostasis, inflammatory signals, and oxidative stress.pdfArtículoapplication/pdf59113https://repositorio.cuc.edu.co/bitstreams/68ba7ddb-cc3f-4e1f-87c9-7394557cf7ca/download35e042bb8ed40244f9cd20de05b60549MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-814828https://repositorio.cuc.edu.co/bitstreams/7b6569bf-b4d1-408f-a7ba-6a7a075c62db/download2f9959eaf5b71fae44bbf9ec84150c7aMD52TEXTEffects of coconut oil long-term supplementation in Wistar rats during metabolic syndrome - regulation of metabolic conditions involving glucose homeostasis, inflammatory signals, and oxidative stress.pdf.txtEffects of coconut oil long-term supplementation in Wistar rats during metabolic syndrome - regulation of metabolic conditions involving glucose homeostasis, inflammatory signals, and oxidative stress.pdf.txtExtracted texttext/plain2226https://repositorio.cuc.edu.co/bitstreams/bdf4a011-727d-4d4e-9139-8f0bfc2d0127/downloadd7bd30fd293fb21d34bf81788f79048eMD53THUMBNAILEffects of coconut oil long-term supplementation in Wistar rats during metabolic syndrome - regulation of metabolic conditions involving glucose homeostasis, inflammatory signals, and oxidative stress.pdf.jpgEffects of coconut oil long-term supplementation in Wistar rats during metabolic syndrome - regulation of metabolic conditions involving glucose homeostasis, inflammatory signals, and oxidative stress.pdf.jpgGenerated 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ada en las Obras Colectivas.

b.	Distribuir copias o fonogramas de las Obras, exhibirlas públicamente, ejecutarlas públicamente y/o ponerlas a disposición pública, incluyéndolas como incorporadas en Obras Colectivas, según corresponda.

c.	Distribuir copias de las Obras Derivadas que se generen, exhibirlas públicamente, ejecutarlas públicamente y/o ponerlas a disposición pública.
Los derechos mencionados anteriormente pueden ser ejercidos en todos los medios y formatos, actualmente conocidos o que se inventen en el futuro. Los derechos antes mencionados incluyen el derecho a realizar dichas modificaciones en la medida que sean técnicamente necesarias para ejercer los derechos en otro medio o formatos, pero de otra manera usted no está autorizado para realizar obras derivadas. Todos los derechos no otorgados expresamente por el Licenciante quedan por este medio reservados, incluyendo pero sin limitarse a aquellos que se mencionan en las secciones 4(d) y 4(e).

4. Restricciones.
La licencia otorgada en la anterior Sección 3 está expresamente sujeta y limitada por las siguientes restricciones:

a.	Usted puede distribuir, exhibir públicamente, ejecutar públicamente, o poner a disposición pública la Obra sólo bajo las condiciones de esta Licencia, y Usted debe incluir una copia de esta licencia o del Identificador Universal de Recursos de la misma con cada copia de la Obra que distribuya, exhiba públicamente, ejecute públicamente o ponga a disposición pública. No es posible ofrecer o imponer ninguna condición sobre la Obra que altere o limite las condiciones de esta Licencia o el ejercicio de los derechos de los destinatarios otorgados en este documento. No es posible sublicenciar la Obra. Usted debe mantener intactos todos los avisos que hagan referencia a esta Licencia y a la cláusula de limitación de garantías. Usted no puede distribuir, exhibir públicamente, ejecutar públicamente, o poner a disposición pública la Obra con alguna medida tecnológica que controle el acceso o la utilización de ella de una forma que sea inconsistente con las condiciones de esta Licencia. Lo anterior se aplica a la Obra incorporada a una Obra Colectiva, pero esto no exige que la Obra Colectiva aparte de la obra misma quede sujeta a las condiciones de esta Licencia. Si Usted crea una Obra Colectiva, previo aviso de cualquier Licenciante debe, en la medida de lo posible, eliminar de la Obra Colectiva cualquier referencia a dicho Licenciante o al Autor Original, según lo solicitado por el Licenciante y conforme lo exige la cláusula 4(c).

b.	Usted no puede ejercer ninguno de los derechos que le han sido otorgados en la Sección 3 precedente de modo que estén principalmente destinados o directamente dirigidos a conseguir un provecho comercial o una compensación monetaria privada. El intercambio de la Obra por otras obras protegidas por derechos de autor, ya sea a través de un sistema para compartir archivos digitales (digital file-sharing) o de cualquier otra manera no será considerado como estar destinado principalmente o dirigido directamente a conseguir un provecho comercial o una compensación monetaria privada, siempre que no se realice un pago mediante una compensación monetaria en relación con el intercambio de obras protegidas por el derecho de autor.

c.	Si usted distribuye, exhibe públicamente, ejecuta públicamente o ejecuta públicamente en forma digital la Obra o cualquier Obra Derivada u Obra Colectiva, Usted debe mantener intacta toda la información de derecho de autor de la Obra y proporcionar, de forma razonable según el medio o manera que Usted esté utilizando: (i) el nombre del Autor Original si está provisto (o seudónimo, si fuere aplicable), y/o (ii) el nombre de la parte o las partes que el Autor Original y/o el Licenciante hubieren designado para la atribución (v.g., un instituto patrocinador, editorial, publicación) en la información de los derechos de autor del Licenciante, términos de servicios o de otras formas razonables; el título de la Obra si está provisto; en la medida de lo razonablemente factible y, si está provisto, el Identificador Uniforme de Recursos (Uniform Resource Identifier) que el Licenciante especifica para ser asociado con la Obra, salvo que tal URI no se refiera a la nota sobre los derechos de autor o a la información sobre el licenciamiento de la Obra; y en el caso de una Obra Derivada, atribuir el crédito identificando el uso de la Obra en la Obra Derivada (v.g., "Traducción Francesa de la Obra del Autor Original," o "Guión Cinematográfico basado en la Obra original del Autor Original"). Tal crédito puede ser implementado de cualquier forma razonable; en el caso, sin embargo, de Obras Derivadas u Obras Colectivas, tal crédito aparecerá, como mínimo, donde aparece el crédito de cualquier otro autor comparable y de una manera, al menos, tan destacada como el crédito de otro autor comparable.

d.	Para evitar toda confusión, el Licenciante aclara que, cuando la obra es una composición musical:

i.	Regalías por interpretación y ejecución bajo licencias generales. El Licenciante se reserva el derecho exclusivo de autorizar la ejecución pública o la ejecución pública digital de la obra y de recolectar, sea individualmente o a través de una sociedad de gestión colectiva de derechos de autor y derechos conexos (por ejemplo, SAYCO), las regalías por la ejecución pública o por la ejecución pública digital de la obra (por ejemplo Webcast) licenciada bajo licencias generales, si la interpretación o ejecución de la obra está primordialmente orientada por o dirigida a la obtención de una ventaja comercial o una compensación monetaria privada.

ii.	Regalías por Fonogramas. El Licenciante se reserva el derecho exclusivo de recolectar, individualmente o a través de una sociedad de gestión colectiva de derechos de autor y derechos conexos (por ejemplo, los consagrados por la SAYCO), una agencia de derechos musicales o algún agente designado, las regalías por cualquier fonograma que Usted cree a partir de la obra (“versión cover”) y distribuya, en los términos del régimen de derechos de autor, si la creación o distribución de esa versión cover está primordialmente destinada o dirigida a obtener una ventaja comercial o una compensación monetaria privada.

e.	Gestión de Derechos de Autor sobre Interpretaciones y Ejecuciones Digitales (WebCasting). Para evitar toda confusión, el Licenciante aclara que, cuando la obra sea un fonograma, el Licenciante se reserva el derecho exclusivo de autorizar la ejecución pública digital de la obra (por ejemplo, webcast) y de recolectar, individualmente o a través de una sociedad de gestión colectiva de derechos de autor y derechos conexos (por ejemplo, ACINPRO), las regalías por la ejecución pública digital de la obra (por ejemplo, webcast), sujeta a las disposiciones aplicables del régimen de Derecho de Autor, si esta ejecución pública digital está primordialmente dirigida a obtener una ventaja comercial o una compensación monetaria privada.

5. Representaciones, Garantías y Limitaciones de Responsabilidad.
A MENOS QUE LAS PARTES LO ACORDARAN DE OTRA FORMA POR ESCRITO, EL LICENCIANTE OFRECE LA OBRA (EN EL ESTADO EN EL QUE SE ENCUENTRA) “TAL CUAL”, SIN BRINDAR GARANTÍAS DE CLASE ALGUNA RESPECTO DE LA OBRA, YA SEA EXPRESA, IMPLÍCITA, LEGAL O CUALQUIERA OTRA, INCLUYENDO, SIN LIMITARSE A ELLAS, GARANTÍAS DE TITULARIDAD, COMERCIABILIDAD, ADAPTABILIDAD O ADECUACIÓN A PROPÓSITO DETERMINADO, AUSENCIA DE INFRACCIÓN, DE AUSENCIA DE DEFECTOS LATENTES O DE OTRO TIPO, O LA PRESENCIA O AUSENCIA DE ERRORES, SEAN O NO DESCUBRIBLES (PUEDAN O NO SER ESTOS DESCUBIERTOS). ALGUNAS JURISDICCIONES NO PERMITEN LA EXCLUSIÓN DE GARANTÍAS IMPLÍCITAS, EN CUYO CASO ESTA EXCLUSIÓN PUEDE NO APLICARSE A USTED.

6. Limitación de responsabilidad.
A MENOS QUE LO EXIJA EXPRESAMENTE LA LEY APLICABLE, EL LICENCIANTE NO SERÁ RESPONSABLE ANTE USTED POR DAÑO ALGUNO, SEA POR RESPONSABILIDAD EXTRACONTRACTUAL, PRECONTRACTUAL O CONTRACTUAL, OBJETIVA O SUBJETIVA, SE TRATE DE DAÑOS MORALES O PATRIMONIALES, DIRECTOS O INDIRECTOS, PREVISTOS O IMPREVISTOS PRODUCIDOS POR EL USO DE ESTA LICENCIA O DE LA OBRA, AUN CUANDO EL LICENCIANTE HAYA SIDO ADVERTIDO DE LA POSIBILIDAD DE DICHOS DAÑOS. ALGUNAS LEYES NO PERMITEN LA EXCLUSIÓN DE CIERTA RESPONSABILIDAD, EN CUYO CASO ESTA EXCLUSIÓN PUEDE NO APLICARSE A USTED.

7. Término.

a.	Esta Licencia y los derechos otorgados en virtud de ella terminarán automáticamente si Usted infringe alguna condición establecida en ella. Sin embargo, los individuos o entidades que han recibido Obras Derivadas o Colectivas de Usted de conformidad con esta Licencia, no verán terminadas sus licencias, siempre que estos individuos o entidades sigan cumpliendo íntegramente las condiciones de estas licencias. Las Secciones 1, 2, 5, 6, 7, y 8 subsistirán a cualquier terminación de esta Licencia.

b.	Sujeta a las condiciones y términos anteriores, la licencia otorgada aquí es perpetua (durante el período de vigencia de los derechos de autor de la obra). No obstante lo anterior, el Licenciante se reserva el derecho a publicar y/o estrenar la Obra bajo condiciones de licencia diferentes o a dejar de distribuirla en los términos de esta Licencia en cualquier momento; en el entendido, sin embargo, que esa elección no servirá para revocar esta licencia o que deba ser otorgada , bajo los términos de esta licencia), y esta licencia continuará en pleno vigor y efecto a menos que sea terminada como se expresa atrás. La Licencia revocada continuará siendo plenamente vigente y efectiva si no se le da término en las condiciones indicadas anteriormente.

8. Varios.

a.	Cada vez que Usted distribuya o ponga a disposición pública la Obra o una Obra Colectiva, el Licenciante ofrecerá al destinatario una licencia en los mismos términos y condiciones que la licencia otorgada a Usted bajo esta Licencia.

b.	Si alguna disposición de esta Licencia resulta invalidada o no exigible, según la legislación vigente, esto no afectará ni la validez ni la aplicabilidad del resto de condiciones de esta Licencia y, sin acción adicional por parte de los sujetos de este acuerdo, aquélla se entenderá reformada lo mínimo necesario para hacer que dicha disposición sea válida y exigible.

c.	Ningún término o disposición de esta Licencia se estimará renunciada y ninguna violación de ella será consentida a menos que esa renuncia o consentimiento sea otorgado por escrito y firmado por la parte que renuncie o consienta.

d.	Esta Licencia refleja el acuerdo pleno entre las partes respecto a la Obra aquí licenciada. No hay arreglos, acuerdos o declaraciones respecto a la Obra que no estén especificados en este documento. El Licenciante no se verá limitado por ninguna disposición adicional que pueda surgir en alguna comunicación emanada de Usted. Esta Licencia no puede ser modificada sin el consentimiento mutuo por escrito del Licenciante y Usted.
 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