Riesgo de cáncer en agricultores expuestos a glifosato: una revisión sistemática y metaanálisis

The use of herbicides such as glyphosate has increased and at the same time general concern about the increased associated risks. Further, the Environmental Protection Agency-USEPA and the International Agency for Research on Cancer-IARC have discussed the possible association between glyphosate exp...

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Autores:
Llanos Polo, Anyeris
Tipo de recurso:
Fecha de publicación:
2020
Institución:
Corporación Universidad de la Costa
Repositorio:
REDICUC - Repositorio CUC
Idioma:
spa
OAI Identifier:
oai:repositorio.cuc.edu.co:11323/8172
Acceso en línea:
https://hdl.handle.net/11323/8172
https://repositorio.cuc.edu.co/
Palabra clave:
Herbicide
Farmers
Neoplasm
Health
Risk
Exposure
Herbicida
Agricultor
Neoplasia
Salud
Riesgo
Exposición
Rights
openAccess
License
Attribution-NonCommercial-ShareAlike 4.0 International
id RCUC2_371ce7c050c1d4ec3a330ca8d46d20c0
oai_identifier_str oai:repositorio.cuc.edu.co:11323/8172
network_acronym_str RCUC2
network_name_str REDICUC - Repositorio CUC
repository_id_str
dc.title.spa.fl_str_mv Riesgo de cáncer en agricultores expuestos a glifosato: una revisión sistemática y metaanálisis
title Riesgo de cáncer en agricultores expuestos a glifosato: una revisión sistemática y metaanálisis
spellingShingle Riesgo de cáncer en agricultores expuestos a glifosato: una revisión sistemática y metaanálisis
Herbicide
Farmers
Neoplasm
Health
Risk
Exposure
Herbicida
Agricultor
Neoplasia
Salud
Riesgo
Exposición
title_short Riesgo de cáncer en agricultores expuestos a glifosato: una revisión sistemática y metaanálisis
title_full Riesgo de cáncer en agricultores expuestos a glifosato: una revisión sistemática y metaanálisis
title_fullStr Riesgo de cáncer en agricultores expuestos a glifosato: una revisión sistemática y metaanálisis
title_full_unstemmed Riesgo de cáncer en agricultores expuestos a glifosato: una revisión sistemática y metaanálisis
title_sort Riesgo de cáncer en agricultores expuestos a glifosato: una revisión sistemática y metaanálisis
dc.creator.fl_str_mv Llanos Polo, Anyeris
dc.contributor.advisor.spa.fl_str_mv Schnorr, Carlos Eduardo
Silva Oliveira, Luis Felipe
dc.contributor.author.spa.fl_str_mv Llanos Polo, Anyeris
dc.subject.eng.fl_str_mv Herbicide
Farmers
Neoplasm
Health
Risk
Exposure
topic Herbicide
Farmers
Neoplasm
Health
Risk
Exposure
Herbicida
Agricultor
Neoplasia
Salud
Riesgo
Exposición
dc.subject.spa.fl_str_mv Herbicida
Agricultor
Neoplasia
Salud
Riesgo
Exposición
description The use of herbicides such as glyphosate has increased and at the same time general concern about the increased associated risks. Further, the Environmental Protection Agency-USEPA and the International Agency for Research on Cancer-IARC have discussed the possible association between glyphosate exposure and cancer in farmers reporting different results. Thus, the objective of this systematic review and meta-analysis was to evaluate the risk of cancer in farmers occupationally exposed to glyphosate. Cohort studies, case controls and systematic reviews were included, whose population was farmers exposed to glyphosate, and with a medical diagnosis of cancer. In total, 313 potential studies were identified, of which only 6 studies met the inclusion and exclusion criteria. The meta-analysis revealed a higher risk of non-Hodgkin lymphoma (OR 0.39; 95% CI = 0.35-0.41; Z = 31.37 and p<0.00001), and multiple myeloma (OR 0.04; 95% CI = 0.03-0.05; Z = 30.27 p <0.00001) in exposed farmers compared to farmers not exposed. These results are the basis for future studies on the potential carcinogenic effect in farmers who are exposed to glyphosate on a daily basis. Further, our results seek to contribute to establish safety and health standards for the protection of agricultural workers.
publishDate 2020
dc.date.issued.none.fl_str_mv 2020
dc.date.accessioned.none.fl_str_mv 2021-04-21T20:06:59Z
dc.date.available.none.fl_str_mv 2021-04-21T20:06:59Z
dc.type.spa.fl_str_mv Trabajo de grado - Maestría
dc.type.content.spa.fl_str_mv Text
dc.type.driver.spa.fl_str_mv info:eu-repo/semantics/masterThesis
dc.type.redcol.spa.fl_str_mv http://purl.org/redcol/resource_type/TM
dc.type.version.spa.fl_str_mv info:eu-repo/semantics/acceptedVersion
status_str acceptedVersion
dc.identifier.citation.spa.fl_str_mv Llanos, A. (2020) Riesgo de cáncer en agricultores expuestos a glifosato: una revisión sistemática y metaanálisis. Trabajo de Maestría. Recuperado de https://hdl.handle.net/11323/8172
dc.identifier.uri.spa.fl_str_mv https://hdl.handle.net/11323/8172
dc.identifier.instname.spa.fl_str_mv Corporación Universidad de la Costa
dc.identifier.reponame.spa.fl_str_mv REDICUC - Repositorio CUC
dc.identifier.repourl.spa.fl_str_mv https://repositorio.cuc.edu.co/
identifier_str_mv Llanos, A. (2020) Riesgo de cáncer en agricultores expuestos a glifosato: una revisión sistemática y metaanálisis. Trabajo de Maestría. Recuperado de https://hdl.handle.net/11323/8172
Corporación Universidad de la Costa
REDICUC - Repositorio CUC
url https://hdl.handle.net/11323/8172
https://repositorio.cuc.edu.co/
dc.language.iso.none.fl_str_mv spa
language spa
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spelling Schnorr, Carlos EduardoSilva Oliveira, Luis FelipeLlanos Polo, Anyeris2021-04-21T20:06:59Z2021-04-21T20:06:59Z2020Llanos, A. (2020) Riesgo de cáncer en agricultores expuestos a glifosato: una revisión sistemática y metaanálisis. Trabajo de Maestría. Recuperado de https://hdl.handle.net/11323/8172https://hdl.handle.net/11323/8172Corporación Universidad de la CostaREDICUC - Repositorio CUChttps://repositorio.cuc.edu.co/The use of herbicides such as glyphosate has increased and at the same time general concern about the increased associated risks. Further, the Environmental Protection Agency-USEPA and the International Agency for Research on Cancer-IARC have discussed the possible association between glyphosate exposure and cancer in farmers reporting different results. Thus, the objective of this systematic review and meta-analysis was to evaluate the risk of cancer in farmers occupationally exposed to glyphosate. Cohort studies, case controls and systematic reviews were included, whose population was farmers exposed to glyphosate, and with a medical diagnosis of cancer. In total, 313 potential studies were identified, of which only 6 studies met the inclusion and exclusion criteria. The meta-analysis revealed a higher risk of non-Hodgkin lymphoma (OR 0.39; 95% CI = 0.35-0.41; Z = 31.37 and p<0.00001), and multiple myeloma (OR 0.04; 95% CI = 0.03-0.05; Z = 30.27 p <0.00001) in exposed farmers compared to farmers not exposed. These results are the basis for future studies on the potential carcinogenic effect in farmers who are exposed to glyphosate on a daily basis. Further, our results seek to contribute to establish safety and health standards for the protection of agricultural workers.El uso de herbicidas como el glifosato ha aumentado y paralelamente ha incrementado también la preocupación general acerca de los riesgos asociados. Incluso la Environmetal Protetion Agency- USEPA y la International Agency for Research on Cancer- IARC han debatido de la posible asociación entre la exposición al glifosato y el cáncer en agricultores obteniendo diferentes resultados. Así, el objetivo de esta revisión sistemática y metaanálisis fue evaluar el riesgo de cáncer en agricultores ocupacionalmente expuestos al glifosato. En la revisión fueron incluidos estudios de cohorte, casos control y revisiones sistemáticas, cuya población fueron agricultores expuesto al glifosato, y con diagnóstico médico de cáncer. En total se identificaron 313 estudios potenciales, de los cuales solo 6 estudios cumplieron con los criterios de inclusión y exclusión. El metaanálisis reveló un mayor riesgo de linfoma de no Hodgkin (OR 0,39; IC95%=0,35-0,41; Z= 31.37 y p< 0.00001), linfoma de Hodgkin (OR 0,36; IC95%= 0,15- 0,30; Z= 9.86 y p< 0.00001), y mieloma múltiple (OR 0,04; IC95%= 0,03- 0,05; Z= 30.27 p< 0.00001) en los agricultores expuestos en comparación con los agricultores no expuestos. Estos resultados son la base para estudios futuros sobre el potencial efecto cancerígeno en los agricultores que se exponen a diario al glifosato. Además, buscan contribuir para establecer normas de seguridad y salud en protección de los trabajadores agrícolas.Llanos Polo, Anyerisapplication/pdfspaCorporación Universidad de la CostaMaestría de Investigación en Desarrollo Sostenible MIDESAttribution-NonCommercial-ShareAlike 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-sa/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2HerbicideFarmersNeoplasmHealthRiskExposureHerbicidaAgricultorNeoplasiaSaludRiesgoExposiciónRiesgo de cáncer en agricultores expuestos a glifosato: una revisión sistemática y metaanálisisTrabajo de grado - MaestríaTextinfo:eu-repo/semantics/masterThesishttp://purl.org/redcol/resource_type/TMinfo:eu-repo/semantics/acceptedVersionAcquavella, J., Garabrant, D., Marsh, G., Sorahan, T., & Weed, D. L. (2016). 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