Biocatalysis: an eco-friendly scenario for the manufacturing of APIs

Nowadays, the worldwide demand for Active Pharmaceutical Ingredients (APIs) requires novel, cost-effective, safe, and environmentally friendly synthetic processes. Given this scenario, biocatalysis has started to take an ever-growing impact on industrial chemical processes [1,2]. The application of...

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Autores:
Fernández-Lucas, Jesús
Tipo de recurso:
Article of investigation
Fecha de publicación:
2023
Institución:
Corporación Universidad de la Costa
Repositorio:
REDICUC - Repositorio CUC
Idioma:
eng
OAI Identifier:
oai:repositorio.cuc.edu.co:11323/10446
Acceso en línea:
https://hdl.handle.net/11323/10446
https://repositorio.cuc.edu.co/
Palabra clave:
Biocatalysis
Manufacturing
APIs
Rights
openAccess
License
Atribución 4.0 Internacional (CC BY 4.0)
Description
Summary:Nowadays, the worldwide demand for Active Pharmaceutical Ingredients (APIs) requires novel, cost-effective, safe, and environmentally friendly synthetic processes. Given this scenario, biocatalysis has started to take an ever-growing impact on industrial chemical processes [1,2]. The application of enzymes to catalyze industrial reactions has the potential to make chemical processes less contaminant and more sustainable, in accordance with the concept and principles of Green Chemistry [3]. Moreover, biocatalysis offers additional advantages, such as the possibility to perform one-pot reactions, a higher region- and stereo-selectivity, or the absence of intermediates that require tedious purification steps, which make enzyme-mediated processes a powerful ally for a successful industrial implementation of a process.