Antimicrobial resistance trends in methicillin-resistant and methicillin-susceptible Staphylococcus aureus and Staphylococcus epidermidisisolates obtained from patients admitted to intensive care units. 2010-2015
Introduction: The emergence and spread of antimicrobial-resistant strains in hospitals, mainly in intensive care units (ICU), has become a serious public health problem.Objective: To analyze the temporal trends of bacterial resistance phenotypes of methicillin-resistant and methicillin-susceptible S...
- Autores:
-
Castro Orozco, Raimundo
Consuegra-Mayor, Claudia
Mejía-Chávez, Gloria
Hernández-Escolar, Jacqueline
Alvis-Guzmán, Nelson
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2019
- Institución:
- Corporación Universidad de la Costa
- Repositorio:
- REDICUC - Repositorio CUC
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.cuc.edu.co:11323/7474
- Acceso en línea:
- https://hdl.handle.net/11323/7474
https://doi.org/10.15446/revfacmed.v67n3.65741
https://repositorio.cuc.edu.co/
- Palabra clave:
- Staphylococcus Aureus
Staphylococcus Epidermidis
Staphylococcal Infections
Methicillin Resistance
Methicillin-Resistant Staphylococcus Aureus
Intensive Care Units (MeSH)
- Rights
- openAccess
- License
- Attribution-NonCommercial-NoDerivatives 4.0 International
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Antimicrobial resistance trends in methicillin-resistant and methicillin-susceptible Staphylococcus aureus and Staphylococcus epidermidisisolates obtained from patients admitted to intensive care units. 2010-2015 |
| dc.title.translated.spa.fl_str_mv |
Tendencias de resistencia antimicrobiana en Staphylococcus aureus y Staphylococcus epidermidis resistentes y susceptibles a meticilina aislados, obtenidos en unidades de cuidados intensivos, 2010-2015 |
| title |
Antimicrobial resistance trends in methicillin-resistant and methicillin-susceptible Staphylococcus aureus and Staphylococcus epidermidisisolates obtained from patients admitted to intensive care units. 2010-2015 |
| spellingShingle |
Antimicrobial resistance trends in methicillin-resistant and methicillin-susceptible Staphylococcus aureus and Staphylococcus epidermidisisolates obtained from patients admitted to intensive care units. 2010-2015 Staphylococcus Aureus Staphylococcus Epidermidis Staphylococcal Infections Methicillin Resistance Methicillin-Resistant Staphylococcus Aureus Intensive Care Units (MeSH) |
| title_short |
Antimicrobial resistance trends in methicillin-resistant and methicillin-susceptible Staphylococcus aureus and Staphylococcus epidermidisisolates obtained from patients admitted to intensive care units. 2010-2015 |
| title_full |
Antimicrobial resistance trends in methicillin-resistant and methicillin-susceptible Staphylococcus aureus and Staphylococcus epidermidisisolates obtained from patients admitted to intensive care units. 2010-2015 |
| title_fullStr |
Antimicrobial resistance trends in methicillin-resistant and methicillin-susceptible Staphylococcus aureus and Staphylococcus epidermidisisolates obtained from patients admitted to intensive care units. 2010-2015 |
| title_full_unstemmed |
Antimicrobial resistance trends in methicillin-resistant and methicillin-susceptible Staphylococcus aureus and Staphylococcus epidermidisisolates obtained from patients admitted to intensive care units. 2010-2015 |
| title_sort |
Antimicrobial resistance trends in methicillin-resistant and methicillin-susceptible Staphylococcus aureus and Staphylococcus epidermidisisolates obtained from patients admitted to intensive care units. 2010-2015 |
| dc.creator.fl_str_mv |
Castro Orozco, Raimundo Consuegra-Mayor, Claudia Mejía-Chávez, Gloria Hernández-Escolar, Jacqueline Alvis-Guzmán, Nelson |
| dc.contributor.author.spa.fl_str_mv |
Castro Orozco, Raimundo Consuegra-Mayor, Claudia Mejía-Chávez, Gloria Hernández-Escolar, Jacqueline Alvis-Guzmán, Nelson |
| dc.subject.spa.fl_str_mv |
Staphylococcus Aureus Staphylococcus Epidermidis Staphylococcal Infections Methicillin Resistance Methicillin-Resistant Staphylococcus Aureus Intensive Care Units (MeSH) |
| topic |
Staphylococcus Aureus Staphylococcus Epidermidis Staphylococcal Infections Methicillin Resistance Methicillin-Resistant Staphylococcus Aureus Intensive Care Units (MeSH) |
| description |
Introduction: The emergence and spread of antimicrobial-resistant strains in hospitals, mainly in intensive care units (ICU), has become a serious public health problem.Objective: To analyze the temporal trends of bacterial resistance phenotypes of methicillin-resistant and methicillin-susceptible Staphylococcus aureus and Staphylococcus epidermidis isolates obtained from ICU patients of a tertiary hospital in Cartagena, Colombia, between 2010 and 2015.Methods: A cross-sectional study was carried out between January 2010 and December 2015. Methicillin-resistant and Methicillin-susceptible S. aureus and S. epidermidis isolates (MRSA, MSSA, MRSE and MSSE) were used. Culture medium microdilution technique was used to detect minimal inhibitory concentration (MIC).Results: 313 Staphylococcus spp. isolates were identified, and most of them were methicillin-resistant (63.6%). Methicillin-resistant S. aureus (MRSA) and methicillin-resistant S. epidermidis (MRSE) strains represented 13.7% and 27.8%, respectively, of the total sample. The highest antibiotic resistance values in MRSA and MRSE isolates were observed for the following antibiotics: erythromycin (57.6% and 81.2%, respectively), clindamycin (54.6% and 71.0%), ciprofloxacin (48.4% and 36.4%) and trimethoprim-sulfametoxazole (36.4% and 51.4%). Conclusions: The results reported here suggest the need to rethink the control strategies designed to minimize antibiotic resistance in the hospital in which the study was conducted. |
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2019 |
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2019 |
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2020-11-24T16:32:47Z |
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2020-11-24T16:32:47Z |
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1. Morillo-Garcia A, Aldana-Espinal JM, Olry de Labry-Lima A, Valen-cia-Martín R, López-Márquez R, Loscertales-Abril M, et al.Hospital costs associated with nosocomial infections in a pediatric intensive care unit. Gac Sanit. 2015;29(4):282-7. http://doi.org/f3gxt9. 2. Lee CR, Cho IH, Jeong BC, Lee SH. Strategies to minimize antibiotic resistance. Int J Environ Res Public Health. 2013;10(9):4274-305. http://doi.org/gchm6p. 3. Friedman ND, Temkin E, Carmeli Y. The negative impact of antibiotic re-sistance. Clinic Microbiol Infect. 2016;22(5):416-422. http://doi.org/f8n8mp. 4. Morales FE, Villa LA, Fernández PB, López MA, Mella S, Muñoz M. Evolución del consumo de antimicrobianos de uso restringido y tendencia de la susceptibilidad in vitro en el Hospital Regional de Concepción, Chile. Rev Chilena Infectol. 2012;29(5):492-8. http://doi.org/c4c8. 5. Brusselaers N, Vogelaers D, Blot S. The rising problem of antimicro-bial resistance in the intensive care unit. Ann Intensive Care. 2011;1:47. http://doi.org/dfvghv. 6. Briceño I, Suarez ME. Resistencia Bacteriana en la Unidad de Cuidados Intensivos del Hospital Universitario de Los Andes. MEDICRIT. 2006 [cited 2019 Apr 10];3(2):30-42. Available from: https://bit.ly/2KlBmdA. 7. López-Pueyo MJ, Barcenilla-Gaite F, Amaya-Villar R, Garna-cho-Montero J. Multirresistencia antibiótica en unidades de críticos. Med Intensiva. 2011;35(1):41-53. http://doi.org/dx2x87. 8. De Waele JJ, Akova M, Antonelli M, Canton R, Carlet J, De Backer D, et al.Antimicrobial resistance and antibiotic stewardship programs in the ICU: insistence and persistence in the fight against resistance. A position statement from ESICM/ESCMID/WAAAR round table on multi-drug resistance. Intensive Care Med. 2018;44(2):189-96. http://doi.org/gc4xmn. 9. Bassetti M, Poulakou G, Timsit JF. Focus on antimicrobial use in the era of increasing antimicrobial resistance in ICU. Intensive Care Med. 2016;42(6):955-8. http://doi.org/c4c9. 10. Castro-Orozco R, Barreto-Maya AC, Guzmán-Álvarez H, Orte-ga-Quiroz RJ, Benítez-Peña L. [Antimicrobial resistance pattern for gram-negative uropathogens isolated from hospitalised patients and out-patients in Cartagena, 2005-2008]. Rev Salud Pública. 2010;12(6):1010-9. 11. Cook E, Marchaim D, Kaye KS. Building a successful infection pre-vention program: key components, processes, and economics. Infect Dis Clin North Am. 2011;25(1):1-19. http://doi.org/b3m92z. 12. De Santis V, Gresoiu M, Corona A, Wilson AP, Singer M. Bacteraemia incidence, causative organisms and resistance patterns, antibiotic strategies and outcomes in a single university hospital ICU: continuing improvement between 2000 and 2013. J Antimicrob Chemother. 2015;70(1):273-8. http://doi.org/f63zzp. 13. Tukenmez Tigen E, Dogru A, Koltka EN, Unlu C, Gura M. Devi-ce-associated nosocomial infection rates and distribution of antimicrobial resistance in a medical-surgical intensive care unit in Turkey. Jpn J Infect Dis. 2014;67(1):5-8. |
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Castro Orozco, RaimundoConsuegra-Mayor, ClaudiaMejía-Chávez, GloriaHernández-Escolar, JacquelineAlvis-Guzmán, Nelson2020-11-24T16:32:47Z2020-11-24T16:32:47Z2019https://hdl.handle.net/11323/7474https://doi.org/10.15446/revfacmed.v67n3.65741Corporación Universidad de la CostaREDICUC - Repositorio CUChttps://repositorio.cuc.edu.co/Introduction: The emergence and spread of antimicrobial-resistant strains in hospitals, mainly in intensive care units (ICU), has become a serious public health problem.Objective: To analyze the temporal trends of bacterial resistance phenotypes of methicillin-resistant and methicillin-susceptible Staphylococcus aureus and Staphylococcus epidermidis isolates obtained from ICU patients of a tertiary hospital in Cartagena, Colombia, between 2010 and 2015.Methods: A cross-sectional study was carried out between January 2010 and December 2015. Methicillin-resistant and Methicillin-susceptible S. aureus and S. epidermidis isolates (MRSA, MSSA, MRSE and MSSE) were used. Culture medium microdilution technique was used to detect minimal inhibitory concentration (MIC).Results: 313 Staphylococcus spp. isolates were identified, and most of them were methicillin-resistant (63.6%). Methicillin-resistant S. aureus (MRSA) and methicillin-resistant S. epidermidis (MRSE) strains represented 13.7% and 27.8%, respectively, of the total sample. The highest antibiotic resistance values in MRSA and MRSE isolates were observed for the following antibiotics: erythromycin (57.6% and 81.2%, respectively), clindamycin (54.6% and 71.0%), ciprofloxacin (48.4% and 36.4%) and trimethoprim-sulfametoxazole (36.4% and 51.4%). Conclusions: The results reported here suggest the need to rethink the control strategies designed to minimize antibiotic resistance in the hospital in which the study was conducted.Castro Orozco, Raimundo-will be generated-orcid-0000-0001-5484-9024-600Consuegra-Mayor, ClaudiaMejía-Chávez, GloriaHernández-Escolar, JacquelineAlvis-Guzmán, Nelsonapplication/pdfengCorporación Universidad de la CostaAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Revista Facultad de Medicinahttps://revistas.unal.edu.co/index.php/revfacmed/article/view/65741Staphylococcus AureusStaphylococcus EpidermidisStaphylococcal InfectionsMethicillin ResistanceMethicillin-Resistant Staphylococcus AureusIntensive Care Units (MeSH)Antimicrobial resistance trends in methicillin-resistant and methicillin-susceptible Staphylococcus aureus and Staphylococcus epidermidisisolates obtained from patients admitted to intensive care units. 2010-2015Tendencias de resistencia antimicrobiana en Staphylococcus aureus y Staphylococcus epidermidis resistentes y susceptibles a meticilina aislados, obtenidos en unidades de cuidados intensivos, 2010-2015Artículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/acceptedVersion1. Morillo-Garcia A, Aldana-Espinal JM, Olry de Labry-Lima A, Valen-cia-Martín R, López-Márquez R, Loscertales-Abril M, et al.Hospital costs associated with nosocomial infections in a pediatric intensive care unit. Gac Sanit. 2015;29(4):282-7. http://doi.org/f3gxt9.2. Lee CR, Cho IH, Jeong BC, Lee SH. Strategies to minimize antibiotic resistance. Int J Environ Res Public Health. 2013;10(9):4274-305. http://doi.org/gchm6p.3. Friedman ND, Temkin E, Carmeli Y. The negative impact of antibiotic re-sistance. Clinic Microbiol Infect. 2016;22(5):416-422. http://doi.org/f8n8mp.4. Morales FE, Villa LA, Fernández PB, López MA, Mella S, Muñoz M. Evolución del consumo de antimicrobianos de uso restringido y tendencia de la susceptibilidad in vitro en el Hospital Regional de Concepción, Chile. Rev Chilena Infectol. 2012;29(5):492-8. http://doi.org/c4c8.5. Brusselaers N, Vogelaers D, Blot S. The rising problem of antimicro-bial resistance in the intensive care unit. Ann Intensive Care. 2011;1:47. http://doi.org/dfvghv.6. Briceño I, Suarez ME. Resistencia Bacteriana en la Unidad de Cuidados Intensivos del Hospital Universitario de Los Andes. MEDICRIT. 2006 [cited 2019 Apr 10];3(2):30-42. Available from: https://bit.ly/2KlBmdA.7. López-Pueyo MJ, Barcenilla-Gaite F, Amaya-Villar R, Garna-cho-Montero J. Multirresistencia antibiótica en unidades de críticos. Med Intensiva. 2011;35(1):41-53. http://doi.org/dx2x87.8. De Waele JJ, Akova M, Antonelli M, Canton R, Carlet J, De Backer D, et al.Antimicrobial resistance and antibiotic stewardship programs in the ICU: insistence and persistence in the fight against resistance. A position statement from ESICM/ESCMID/WAAAR round table on multi-drug resistance. Intensive Care Med. 2018;44(2):189-96. http://doi.org/gc4xmn.9. Bassetti M, Poulakou G, Timsit JF. Focus on antimicrobial use in the era of increasing antimicrobial resistance in ICU. Intensive Care Med. 2016;42(6):955-8. http://doi.org/c4c9.10. Castro-Orozco R, Barreto-Maya AC, Guzmán-Álvarez H, Orte-ga-Quiroz RJ, Benítez-Peña L. [Antimicrobial resistance pattern for gram-negative uropathogens isolated from hospitalised patients and out-patients in Cartagena, 2005-2008]. Rev Salud Pública. 2010;12(6):1010-9.11. Cook E, Marchaim D, Kaye KS. Building a successful infection pre-vention program: key components, processes, and economics. Infect Dis Clin North Am. 2011;25(1):1-19. http://doi.org/b3m92z.12. De Santis V, Gresoiu M, Corona A, Wilson AP, Singer M. Bacteraemia incidence, causative organisms and resistance patterns, antibiotic strategies and outcomes in a single university hospital ICU: continuing improvement between 2000 and 2013. J Antimicrob Chemother. 2015;70(1):273-8. http://doi.org/f63zzp.13. Tukenmez Tigen E, Dogru A, Koltka EN, Unlu C, Gura M. Devi-ce-associated nosocomial infection rates and distribution of antimicrobial resistance in a medical-surgical intensive care unit in Turkey. 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