Antimicrobial resistance trends in methicillin-resistant and methicillin-susceptible Staphylococcus aureus and Staphylococcus epidermidisisolates obtained from patients admitted to intensive care units. 2010-2015

Introduction: The emergence and spread of antimicrobial-resistant strains in hospitals, mainly in intensive care units (ICU), has become a serious public health problem.Objective: To analyze the temporal trends of bacterial resistance phenotypes of methicillin-resistant and methicillin-susceptible Staphylococcus aureus and Staphylococcus epidermidis isolates obtained from ICU patients of a tertiary hospital in Cartagena, Colombia, between 2010 and 2015.Methods: A cross-sectional study was carried out between January 2010 and December 2015. Methicillin-resistant and Methicillin-susceptible S. aureus and S. epidermidis isolates (MRSA, MSSA, MRSE and MSSE) were used. Culture medium microdilution technique was used to detect minimal inhibitory concentration (MIC).Results: 313 Staphylococcus spp. isolates were identified, and most of them were methicillin-resistant (63.6%). Methicillin-resistant S. aureus (MRSA) and methicillin-resistant S. epidermidis (MRSE) strains represented 13.7% and 27.8%, respectively, of the total sample. The highest antibiotic resistance values in MRSA and MRSE isolates were observed for the following antibiotics: erythromycin (57.6% and 81.2%, respectively), clindamycin (54.6% and 71.0%), ciprofloxacin (48.4% and 36.4%) and trimethoprim-sulfametoxazole (36.4% and 51.4%). Conclusions: The results reported here suggest the need to rethink the control strategies designed to minimize antibiotic resistance in the hospital in which the study was conducted.

• Autores: Castro Orozco, Raimundo; Consuegra-Mayor, Claudia; Mejía-Chávez, Gloria; Hernández-Escolar, Jacqueline; Alvis-Guzmán, Nelson
• Tipo de recurso: Article of journal
• Fecha de publicación: 2019
• Institución: Corporación Universidad de la Costa
• Repositorio: REDICUC - Repositorio CUC
• Idioma: eng
• OAI Identifier: oai:repositorio.cuc.edu.co:11323/7474
• Acceso en línea: https://hdl.handle.net/11323/7474; https://doi.org/10.15446/revfacmed.v67n3.65741; https://repositorio.cuc.edu.co/
• Palabra clave: Staphylococcus Aureus; Staphylococcus Epidermidis; Staphylococcal Infections; Methicillin Resistance; Methicillin-Resistant Staphylococcus Aureus; Intensive Care Units (MeSH)
• Rights: openAccess
• License: Attribution-NonCommercial-NoDerivatives 4.0 International