A comprehensive care program achieves high remission rates in rheumatoid arthritis in a middle-income setting. Experience of a center of excellence in Colombia

Management of rheumatoid arthritis (RA) in many Latin-American countries is impaired by fragmentation and scarce healthcare provision, resulting in obstacles to access, diagnosis, and treatment, and consequently in poor health outcomes. The aim of this study is to propose a comprehensive care progra...

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Autores:
Santos Moreno, Pedro Ivan
Alvis Zakzuk, Nelson Jose
Villarreal Peralta, Laura
Carrasquilla Sotomayor, María
Paternina Caicedo, Angel Jose
Alvis Guzman, Nelson Rafael
Tipo de recurso:
Article of journal
Fecha de publicación:
2018
Institución:
Corporación Universidad de la Costa
Repositorio:
REDICUC - Repositorio CUC
Idioma:
eng
OAI Identifier:
oai:repositorio.cuc.edu.co:11323/1667
Acceso en línea:
http://hdl.handle.net/11323/1667
https://repositorio.cuc.edu.co/
Palabra clave:
Center of excellence
Patient-centered care
Rheumatoid arthritis
Treat to target
Rights
openAccess
License
Atribución – No comercial – Compartir igual
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network_acronym_str RCUC2
network_name_str REDICUC - Repositorio CUC
repository_id_str
dc.title.eng.fl_str_mv A comprehensive care program achieves high remission rates in rheumatoid arthritis in a middle-income setting. Experience of a center of excellence in Colombia
title A comprehensive care program achieves high remission rates in rheumatoid arthritis in a middle-income setting. Experience of a center of excellence in Colombia
spellingShingle A comprehensive care program achieves high remission rates in rheumatoid arthritis in a middle-income setting. Experience of a center of excellence in Colombia
Center of excellence
Patient-centered care
Rheumatoid arthritis
Treat to target
title_short A comprehensive care program achieves high remission rates in rheumatoid arthritis in a middle-income setting. Experience of a center of excellence in Colombia
title_full A comprehensive care program achieves high remission rates in rheumatoid arthritis in a middle-income setting. Experience of a center of excellence in Colombia
title_fullStr A comprehensive care program achieves high remission rates in rheumatoid arthritis in a middle-income setting. Experience of a center of excellence in Colombia
title_full_unstemmed A comprehensive care program achieves high remission rates in rheumatoid arthritis in a middle-income setting. Experience of a center of excellence in Colombia
title_sort A comprehensive care program achieves high remission rates in rheumatoid arthritis in a middle-income setting. Experience of a center of excellence in Colombia
dc.creator.fl_str_mv Santos Moreno, Pedro Ivan
Alvis Zakzuk, Nelson Jose
Villarreal Peralta, Laura
Carrasquilla Sotomayor, María
Paternina Caicedo, Angel Jose
Alvis Guzman, Nelson Rafael
dc.contributor.author.spa.fl_str_mv Santos Moreno, Pedro Ivan
Alvis Zakzuk, Nelson Jose
Villarreal Peralta, Laura
Carrasquilla Sotomayor, María
Paternina Caicedo, Angel Jose
Alvis Guzman, Nelson Rafael
dc.subject.eng.fl_str_mv Center of excellence
Patient-centered care
Rheumatoid arthritis
Treat to target
topic Center of excellence
Patient-centered care
Rheumatoid arthritis
Treat to target
description Management of rheumatoid arthritis (RA) in many Latin-American countries is impaired by fragmentation and scarce healthcare provision, resulting in obstacles to access, diagnosis, and treatment, and consequently in poor health outcomes. The aim of this study is to propose a comprehensive care program as a model to provide healthcare to RA patients receiving synthetic DMARDs in a Colombian setting by describing the model and its results. Health outcomes were prospectively collected in all patients entering the program. By protocol, patients are followed up during 24 months using a treat-to-target strategy with a patient-centered care (PCC) model, meaning that a patient should be seen by rheumatologist, physical and occupational therapist, physiatrist, nutritionist and psychologist, at least three times a year according to disease activity by DAS28. Otherwise, patients receive standard therapy. The incidence of remission and low disease activity (LDA) was calculated by periods of follow-up. A total of 968 patients entered the program from January 2015 to December 2016; 80.2% were women. At baseline, 41% of patients were in remission, 17% in LDA and 42% in MDS/SDA. At 24 months of follow-up, 66% were in remission, 18% in LDA and only 16% in MDS/SDA. Regarding DAS28, the mean at the beginning of the time analysis was 3.1 (SD 1.0) and after 24 months it was 2.4 (SD 0.7), showing a statistically significant improvement (p < 0.001). In all patients, the reduction of disease activity was 65% (95% CI, 58–71). Patients entering the PCC program benefited from a global improvement in disease activity in terms of DAS28.
publishDate 2018
dc.date.accessioned.none.fl_str_mv 2018-11-21T20:19:09Z
dc.date.available.none.fl_str_mv 2018-11-21T20:19:09Z
dc.date.issued.none.fl_str_mv 2018-03-01
dc.type.spa.fl_str_mv Artículo de revista
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_2df8fbb1
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dc.type.content.spa.fl_str_mv Text
dc.type.driver.spa.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.issn.spa.fl_str_mv 01728172
dc.identifier.uri.spa.fl_str_mv http://hdl.handle.net/11323/1667
dc.identifier.doi.spa.fl_str_mv DOI: 10.1007/s00296-017-3903-2
dc.identifier.instname.spa.fl_str_mv Corporación Universidad de la Costa
dc.identifier.reponame.spa.fl_str_mv REDICUC - Repositorio CUC
dc.identifier.repourl.spa.fl_str_mv https://repositorio.cuc.edu.co/
identifier_str_mv 01728172
DOI: 10.1007/s00296-017-3903-2
Corporación Universidad de la Costa
REDICUC - Repositorio CUC
url http://hdl.handle.net/11323/1667
https://repositorio.cuc.edu.co/
dc.language.iso.none.fl_str_mv eng
language eng
dc.rights.spa.fl_str_mv Atribución – No comercial – Compartir igual
dc.rights.accessrights.spa.fl_str_mv info:eu-repo/semantics/openAccess
dc.rights.coar.spa.fl_str_mv http://purl.org/coar/access_right/c_abf2
rights_invalid_str_mv Atribución – No comercial – Compartir igual
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.publisher.spa.fl_str_mv Rheumatology International
institution Corporación Universidad de la Costa
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spelling Santos Moreno, Pedro Ivanb72f970ada5db87243a728d23c32b87aAlvis Zakzuk, Nelson Josee8e4e8b7760b42a826bf860af8dba139Villarreal Peralta, Laura099fe9a5ad420ee57bb3403b38c45a92Carrasquilla Sotomayor, Maríaa72e1875265eedb090ed9210388404fcPaternina Caicedo, Angel Jose5772d8b5c928bdf3c863f3d060ade1cbAlvis Guzman, Nelson Rafael6248ccf71d6d3b55f5c54cca9315c03a2018-11-21T20:19:09Z2018-11-21T20:19:09Z2018-03-0101728172http://hdl.handle.net/11323/1667DOI: 10.1007/s00296-017-3903-2Corporación Universidad de la CostaREDICUC - Repositorio CUChttps://repositorio.cuc.edu.co/Management of rheumatoid arthritis (RA) in many Latin-American countries is impaired by fragmentation and scarce healthcare provision, resulting in obstacles to access, diagnosis, and treatment, and consequently in poor health outcomes. The aim of this study is to propose a comprehensive care program as a model to provide healthcare to RA patients receiving synthetic DMARDs in a Colombian setting by describing the model and its results. Health outcomes were prospectively collected in all patients entering the program. By protocol, patients are followed up during 24 months using a treat-to-target strategy with a patient-centered care (PCC) model, meaning that a patient should be seen by rheumatologist, physical and occupational therapist, physiatrist, nutritionist and psychologist, at least three times a year according to disease activity by DAS28. Otherwise, patients receive standard therapy. The incidence of remission and low disease activity (LDA) was calculated by periods of follow-up. A total of 968 patients entered the program from January 2015 to December 2016; 80.2% were women. At baseline, 41% of patients were in remission, 17% in LDA and 42% in MDS/SDA. At 24 months of follow-up, 66% were in remission, 18% in LDA and only 16% in MDS/SDA. Regarding DAS28, the mean at the beginning of the time analysis was 3.1 (SD 1.0) and after 24 months it was 2.4 (SD 0.7), showing a statistically significant improvement (p < 0.001). In all patients, the reduction of disease activity was 65% (95% CI, 58–71). Patients entering the PCC program benefited from a global improvement in disease activity in terms of DAS28.engRheumatology InternationalAtribución – No comercial – Compartir igualinfo:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Center of excellencePatient-centered careRheumatoid arthritisTreat to targetA comprehensive care program achieves high remission rates in rheumatoid arthritis in a middle-income setting. 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