Submerged cultivation of Nigrospora sp. in batch and fed-batch modes for microbial oil production
Microbial lipids are a valuable source of potential biofuels and essential polyunsaturated fatty acids. The optimization of the fermentation conditions is a strategy that affects the total lipid concentration. The genus Nigrospora sp. has been the target of investigations based on its potential bioh...
- Autores:
-
Tonato, Denise
Brun, Thiarles
Luft, Luciana
Nascimento dos Santos, Maicon Sérgio
Drumm, Fernanda Caroline
Grassi, Patrícia
georgin, jordana
Kuhn, Raquel C.
Zabot, Giovani L.
Mazutti, Marcio A.
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2023
- Institución:
- Corporación Universidad de la Costa
- Repositorio:
- REDICUC - Repositorio CUC
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.cuc.edu.co:11323/10570
- Acceso en línea:
- https://hdl.handle.net/11323/10570
https://repositorio.cuc.edu.co/
- Palabra clave:
- Agroindustrial residue
Fatty acids
Lipid accumulation
Oleaginous microorganisms
Stirred tank bioreactor
- Rights
- embargoedAccess
- License
- Atribución 4.0 Internacional (CC BY 4.0)
Summary: | Microbial lipids are a valuable source of potential biofuels and essential polyunsaturated fatty acids. The optimization of the fermentation conditions is a strategy that affects the total lipid concentration. The genus Nigrospora sp. has been the target of investigations based on its potential bioherbicidal action. Therefore, this study developed a strategy to maximize the biomass concentration and lipid accumulation by Nigrospora sp. in submerged fermentation. Different media compositions and process variables were investigated in shaken flasks and bioreactor in batch and fed-batch modes. Maximum biomass concentration and lipid accumulations were 40.17 g/L and 21.32 wt% in the bioreactor, which was 2.1 and 5.4 times higher than the same condition in shaken flasks, respectively. This study presents relevant information to the production of fungal lipids since few investigations are exploring the fed-batch strategy to increase the yield of fungi lipids, as well as few studies investigating Nigrospora sp. to produce lipids. |
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