Evolutionary and sequence-based relationships in bacterial AdoMet-dependent non-coding RNA methyltransferases

RNA post-transcriptional modification is an exciting field of research that has evidenced this editing process as a sophisticated epigenetic mechanism to fine tune the ribosome function and to control gene expression. Although tRNA modifications seem to be more relevant for the ribosome function and...

Full description

Autores:
Tipo de recurso:
Fecha de publicación:
2014
Institución:
Ministerio de Ciencia, Tecnología e Innovación
Repositorio:
Repositorio Minciencias
Idioma:
eng
OAI Identifier:
oai:repositorio.minciencias.gov.co:20.500.14143/34128
Acceso en línea:
http://repositorio.colciencias.gov.co/handle/11146/34128
Palabra clave:
Molecular evolution
Conserved sequnce motifs
Antibiotic resistance
RNA methyltransferases
Bioquímica
Bacterias
Secuencia de aminoácidos
Penisilinas
Rights
License
http://purl.org/coar/access_right/c_abf2
id RCENDOC_f19af0b021a2464776e15defd3b29995
oai_identifier_str oai:repositorio.minciencias.gov.co:20.500.14143/34128
network_acronym_str RCENDOC
network_name_str Repositorio Minciencias
repository_id_str
dc.title.es_CO.fl_str_mv Evolutionary and sequence-based relationships in bacterial AdoMet-dependent non-coding RNA methyltransferases
title Evolutionary and sequence-based relationships in bacterial AdoMet-dependent non-coding RNA methyltransferases
spellingShingle Evolutionary and sequence-based relationships in bacterial AdoMet-dependent non-coding RNA methyltransferases
Molecular evolution
Conserved sequnce motifs
Antibiotic resistance
RNA methyltransferases
Bioquímica
Bacterias
Secuencia de aminoácidos
Penisilinas
title_short Evolutionary and sequence-based relationships in bacterial AdoMet-dependent non-coding RNA methyltransferases
title_full Evolutionary and sequence-based relationships in bacterial AdoMet-dependent non-coding RNA methyltransferases
title_fullStr Evolutionary and sequence-based relationships in bacterial AdoMet-dependent non-coding RNA methyltransferases
title_full_unstemmed Evolutionary and sequence-based relationships in bacterial AdoMet-dependent non-coding RNA methyltransferases
title_sort Evolutionary and sequence-based relationships in bacterial AdoMet-dependent non-coding RNA methyltransferases
dc.subject.keyword.es_CO.fl_str_mv Molecular evolution
Conserved sequnce motifs
Antibiotic resistance
RNA methyltransferases
topic Molecular evolution
Conserved sequnce motifs
Antibiotic resistance
RNA methyltransferases
Bioquímica
Bacterias
Secuencia de aminoácidos
Penisilinas
dc.subject.spines.es_CO.fl_str_mv Bioquímica
Bacterias
Secuencia de aminoácidos
Penisilinas
description RNA post-transcriptional modification is an exciting field of research that has evidenced this editing process as a sophisticated epigenetic mechanism to fine tune the ribosome function and to control gene expression. Although tRNA modifications seem to be more relevant for the ribosome function and cell physiology as a whole, some rRNA modifications have also been seen to play pivotal roles, essentially those located in central ribosome region. RNA methylation at nucleobases and ribose moieties of nucleotides appear to frequently modulate its chemistry and structure. RNA methyltransferases comprise a superfamily of highly specialized enzymes that accomplish a wide variety of modifications. These enzymes exhibit a poor degree of sequence similarity in spite of using a common reaction cofactor and modifying the same substrate type.
publishDate 2014
dc.date.issued.none.fl_str_mv 2014
dc.date.accessioned.none.fl_str_mv 2019-03-25T18:18:18Z
dc.date.available.none.fl_str_mv 2019-03-25T18:18:18Z
dc.type.es_CO.fl_str_mv Artículo científico
dc.type.coarversion.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_2df8fbb1
dc.type.driver.es_CO.fl_str_mv info:eu-repo/semantics/article
dc.identifier.issn.none.fl_str_mv 1756-0500
dc.identifier.uri.none.fl_str_mv http://repositorio.colciencias.gov.co/handle/11146/34128
dc.identifier.bibliographicCitation.es_CO.fl_str_mv Contiene 106 referencias bibliográficas. Véase el documento adjunto
identifier_str_mv 1756-0500
Contiene 106 referencias bibliográficas. Véase el documento adjunto
url http://repositorio.colciencias.gov.co/handle/11146/34128
dc.language.iso.es_CO.fl_str_mv eng
language eng
dc.relation.ispartof.es_CO.fl_str_mv Establecimiento de módulos funcionales de secuencia en familias de metiltransferasas de RNA y su uso en la búsqueda de genes de resistencia a antibióticos en patógenos humanos. La publicación completa está disponible en : <a href="http://repositorio.colciencias.gov.co/handle/11146/34125" target="blank">http://repositorio.colciencias.gov.co/handle/11146/34125</a>
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
rights_invalid_str_mv http://purl.org/coar/access_right/c_abf2
dc.format.es_CO.fl_str_mv pdf
dc.format.extent.es_CO.fl_str_mv 15 páginas
dc.coverage.spatial.es_CO.fl_str_mv Colombia
dc.source.es_CO.fl_str_mv BMC Research Notes 2014, 7:440. 1-15
institution Ministerio de Ciencia, Tecnología e Innovación
bitstream.url.fl_str_mv https://repositorio.minciencias.gov.co/bitstreams/5503283a-0d1c-4322-9dd9-9942e8fb0ec9/download
https://repositorio.minciencias.gov.co/bitstreams/f5e819b9-b405-411a-a20a-df13c4cfafbe/download
https://repositorio.minciencias.gov.co/bitstreams/dd64cc22-4a95-417a-8534-20f1ce970349/download
https://repositorio.minciencias.gov.co/bitstreams/4558e70a-26aa-44cb-83b9-f5b325207f7f/download
bitstream.checksum.fl_str_mv c991c59edaabcdb845ea34843f492b85
8a4605be74aa9ea9d79846c1fba20a33
429079e52f342c49301a02e207bfde06
c28e68f187ed39ed9848a2fd02e21c5f
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
MD5
repository.name.fl_str_mv Repositorio Institucional de Minciencias
repository.mail.fl_str_mv cendoc@minciencias.gov.co
_version_ 1811305899954798592
spelling Colombia2019-03-25T18:18:18Z2019-03-25T18:18:18Z20141756-0500http://repositorio.colciencias.gov.co/handle/11146/34128Contiene 106 referencias bibliográficas. Véase el documento adjuntoRNA post-transcriptional modification is an exciting field of research that has evidenced this editing process as a sophisticated epigenetic mechanism to fine tune the ribosome function and to control gene expression. Although tRNA modifications seem to be more relevant for the ribosome function and cell physiology as a whole, some rRNA modifications have also been seen to play pivotal roles, essentially those located in central ribosome region. RNA methylation at nucleobases and ribose moieties of nucleotides appear to frequently modulate its chemistry and structure. RNA methyltransferases comprise a superfamily of highly specialized enzymes that accomplish a wide variety of modifications. These enzymes exhibit a poor degree of sequence similarity in spite of using a common reaction cofactor and modifying the same substrate type.Departamento Administrativo de Ciencia, Tecnología e Innovación [CO] Colciencias5817-569-34856Establecimiento de módulo funcionales de secuencia en familias de metiltransferasas de RNA y su uso en la búsqueda de genes de resistencia a antibióticos en patógenos humanosnopdf15 páginasengEstablecimiento de módulos funcionales de secuencia en familias de metiltransferasas de RNA y su uso en la búsqueda de genes de resistencia a antibióticos en patógenos humanos. La publicación completa está disponible en : <a href="http://repositorio.colciencias.gov.co/handle/11146/34125" target="blank">http://repositorio.colciencias.gov.co/handle/11146/34125</a>BMC Research Notes 2014, 7:440. 1-15Evolutionary and sequence-based relationships in bacterial AdoMet-dependent non-coding RNA methyltransferasesArtículo científicoinfo:eu-repo/semantics/articlehttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_2df8fbb1Entidades gubernamentalesProfesoresInvestigadoresMolecular evolutionConserved sequnce motifsAntibiotic resistanceRNA methyltransferasesBioquímicaBacteriasSecuencia de aminoácidosPenisilinashttp://purl.org/coar/access_right/c_abf2Benítez Páez, AlfonsoMosquera Rendón, JeannethCárdenas Brito, SoniaPineda, Juan D.Corredor Rodríguez, MauricioCentro de Investigación y Desarrollo en BiotecnologíaUniversidad de Antioquia, UdeAUniversidad Cooperativa de Colombia, UCC2015-08-10Programa Nacional de BiotecnologíaComunidad científica colombiana0020-2013Artículos de investigaciónPublicationORIGINALEvolutionary and sequencebased relationships in bacterial Ado Met dependet non coding RNA methyltransferases.pdfEvolutionary and sequencebased relationships in bacterial Ado Met dependet non coding RNA methyltransferases.pdfArticulo BMC Research Notesapplication/pdf1418281https://repositorio.minciencias.gov.co/bitstreams/5503283a-0d1c-4322-9dd9-9942e8fb0ec9/downloadc991c59edaabcdb845ea34843f492b85MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://repositorio.minciencias.gov.co/bitstreams/f5e819b9-b405-411a-a20a-df13c4cfafbe/download8a4605be74aa9ea9d79846c1fba20a33MD52TEXTEvolutionary and sequencebased relationships in bacterial Ado Met dependet non coding RNA methyltransferases.pdf.txtEvolutionary and sequencebased relationships in bacterial Ado Met dependet non coding RNA methyltransferases.pdf.txtExtracted texttext/plain15https://repositorio.minciencias.gov.co/bitstreams/dd64cc22-4a95-417a-8534-20f1ce970349/download429079e52f342c49301a02e207bfde06MD55THUMBNAILEvolutionary and sequencebased relationships in bacterial Ado Met dependet non coding RNA methyltransferases.pdf.jpgEvolutionary and sequencebased relationships in bacterial Ado Met dependet non coding RNA methyltransferases.pdf.jpgGenerated Thumbnailimage/jpeg18353https://repositorio.minciencias.gov.co/bitstreams/4558e70a-26aa-44cb-83b9-f5b325207f7f/downloadc28e68f187ed39ed9848a2fd02e21c5fMD5620.500.14143/34128oai:repositorio.minciencias.gov.co:20.500.14143/341282023-11-29 17:45:53.308restrictedhttps://repositorio.minciencias.gov.coRepositorio Institucional de Mincienciascendoc@minciencias.gov.co

Publicaciones similares