DNA Immunization: evaluation of genetic vaccine potential of PFR in trypanosomatidae using the leishmania model, phase 11
1 documento
- Autores:
-
Gore Saravia, Nancy
- Tipo de recurso:
- Investigation report
- Fecha de publicación:
- 2001
- Institución:
- Ministerio de Ciencia, Tecnología e Innovación
- Repositorio:
- Repositorio Minciencias
- Idioma:
- spa
- OAI Identifier:
- oai:repositorio.minciencias.gov.co:20.500.14143/50100
- Acceso en línea:
- https://repositorio.minciencias.gov.co/handle/20.500.14143/50100
- Palabra clave:
- Vacunas
Proyectos de investigación
Parásitos
Leishmania
Inmunización
- Rights
- openAccess
- License
- https://creativecommons.org/licenses/by/4.0/
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DNA Immunization: evaluation of genetic vaccine potential of PFR in trypanosomatidae using the leishmania model, phase 11 |
| title |
DNA Immunization: evaluation of genetic vaccine potential of PFR in trypanosomatidae using the leishmania model, phase 11 |
| spellingShingle |
DNA Immunization: evaluation of genetic vaccine potential of PFR in trypanosomatidae using the leishmania model, phase 11 Vacunas Proyectos de investigación Parásitos Leishmania Inmunización |
| title_short |
DNA Immunization: evaluation of genetic vaccine potential of PFR in trypanosomatidae using the leishmania model, phase 11 |
| title_full |
DNA Immunization: evaluation of genetic vaccine potential of PFR in trypanosomatidae using the leishmania model, phase 11 |
| title_fullStr |
DNA Immunization: evaluation of genetic vaccine potential of PFR in trypanosomatidae using the leishmania model, phase 11 |
| title_full_unstemmed |
DNA Immunization: evaluation of genetic vaccine potential of PFR in trypanosomatidae using the leishmania model, phase 11 |
| title_sort |
DNA Immunization: evaluation of genetic vaccine potential of PFR in trypanosomatidae using the leishmania model, phase 11 |
| dc.creator.fl_str_mv |
Gore Saravia, Nancy |
| dc.contributor.author.none.fl_str_mv |
Gore Saravia, Nancy |
| dc.subject.lemb.none.fl_str_mv |
Vacunas Proyectos de investigación |
| topic |
Vacunas Proyectos de investigación Parásitos Leishmania Inmunización |
| dc.subject.proposal.fra.fl_str_mv |
Parásitos |
| dc.subject.proposal.spa.fl_str_mv |
Leishmania |
| dc.subject.proposal.ita.fl_str_mv |
Inmunización |
| description |
1 documento |
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2001 |
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2001-08-31 |
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2023-12-22T18:02:13Z |
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2023-12-22T18:02:13Z |
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Informe de investigación |
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Atribución 4.0 Internacional (CC BY 4.0) |
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openAccess |
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22 p. |
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application/pdf |
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Colciencias CIDEIM |
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Gore Saravia, Nancy2023-12-22T18:02:13Z2023-12-22T18:02:13Z2001-08-31https://repositorio.minciencias.gov.co/handle/20.500.14143/501001 documentoDuring their life cycle, Leishmania parasites multiply as flagellated promastigotes within the alimentary tract of the sand fly vector (genus Lufzomyia) and subsequently migrate anteriorly. During feeding, the sand fly transmits flagellated promastigotes to the mammalian host that enter macrophages and transform into aflagellated amastigotes. The presence of a flagellum consisting of an axonema and a lattice-like structure known as the Paraflagellar Rod (PFR), which has a role in the flagellar moti lit y of the parasite, is a distinguishing characteristic of the promastigote stage.22 p.application/pdfspaColcienciasCIDEIMCalihttps://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessAtribución 4.0 Internacional (CC BY 4.0)http://purl.org/coar/access_right/c_abf2DNA Immunization: evaluation of genetic vaccine potential of PFR in trypanosomatidae using the leishmania model, phase 11Informe de investigaciónhttp://purl.org/coar/resource_type/c_18wshttp://purl.org/coar/resource_type/c_18ghhttp://purl.org/coar/resource_type/c_93fcTextinfo:eu-repo/semantics/reporthttp://purl.org/redcol/resource_type/INFinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85VacunasProyectos de investigaciónParásitosLeishmaniaInmunizaciónEstudiantes, Profesores, Comunidad científica colombiana, etc.• Alexander J, Stimson WH.1988. Sex hormones and the course ot parasitic infection. Parasitology Today, 4: 189-193.• Giannini MSH. 1986. Sex-influenced response in the pathogenesis of cutaneous leishmaniasis in mice. Parasite Immunology, 8:31-37.• Moare, L.L. , Santrich, C. and J.H. Lebowitz 1996. Stage specific express ionof the Leishmania mexicana paraflagellar rod protein PFR-2. Mol. Biochem. Parasitol. 80: 125-135.• Pisetsky OS. 1996. Immune activation by bacterial ONA: a new genetic codeo Immunity. 5:303-310.• Ruiz, A.M., Esteva, M. Cabeza Merkert, P., Laguens, R.P. and E.L. Segura. Protective immunity and pathology induced by inoculation of mice with different subcellular fractions of Trypanosoma cruzi. Acta Tropica 42:299-309.• Segura, E.L. Paulone, J. , and J.A. Cerisola. 1976. Experimental Chagas disease protective activity in relation with subcellular fractions of the parasite. J. Parasitol.62: 131-133.• Segura, E.L., Vazquez, C. Bronzina, A. Campos, J.M., Cerisola, J.A. and S.M.Cappa. 1977. Antigens of the subcellular fractions of Trypanosoma cruzi 11 :Flagella and membrane fractions. J. ProtozooI.24:540--43.• Sharifi 1, FeKri AR, Aflatonian MR, Khamesipour A, Nadim A, Mousavi MR, Momeni AZ, Oowlati Y, Godal T, Zicker F, Smith PG, Modabber F. 1998. Randomised vaccine trial of single dose ot killed Leishmania majar plus BCG 20 against anthroponotic cutaneous leishmaniasis in Sam, Iran. Lancet, 23;351 (9115): 1540-3• Wrightsman, R.A. Miller, M.J., Saborio, J.L. and J.e. Manning. 1995. Pure paraflagellar rod protein protects mice against Trypanosoma cruzi infection. Infec. Immunity. 63: 122-125.• Zimmerman S. , Egeter O., Hausman S, Lipford GS., Rócken M. , Wagner H. and Hegg K: 1998. Cutting edge: CpG oligodeoxynucleotides trigger protective and curative Th1 responses in lethal murine leishmaniasis. The Journal of Immunology. 160: 3627-3630.22200522499DNA Immunization: Evaluation of genetic vaccine potential of PFR in Trypanosomatidae using the Leishmania model, Phase 1122290522499Departamento Administrativo de Ciencia, Tecnología e Innovación [CO] ColcienciasPublicationLICENSElicense.txtlicense.txttext/plain; charset=utf-815543https://repositorio.minciencias.gov.co/bitstreams/37116712-fb0c-40d1-a05b-62a42d8080d9/download73a5432e0b76442b22b026844140d683MD52ORIGINAL2229-05-224-99.pdf2229-05-224-99.pdfapplication/pdf8599109https://repositorio.minciencias.gov.co/bitstreams/9cab3064-5f29-4429-8f6b-da2aa23f8a52/download60321d5617055c898d4865b96c231005MD5120.500.14143/50100oai:repositorio.minciencias.gov.co:20.500.14143/501002023-12-22 18:14:02.106https://creativecommons.org/licenses/by/4.0/restrictedhttps://repositorio.minciencias.gov.coRepositorio Institucional de Mincienciascendoc@minciencias.gov.co |