Detection and genotyping of HPV DNA in a group of unvaccinated young women from Colombia : baseline measures prior to future monitoring program

Q2

Autores:
Puerto, Devi
Reyes, Viviana
Lozano, Cristina
Garcia, Diego
Muñoz, Nubia
Hernandez, Gustavo A.
Sanchez, Laura
Wiesner Ceballos, Carolina
Combita, Alba
Tipo de recurso:
Review article
Fecha de publicación:
2018
Institución:
Pontificia Universidad Javeriana
Repositorio:
Repositorio Universidad Javeriana
Idioma:
eng
OAI Identifier:
oai:repository.javeriana.edu.co:10554/51931
Acceso en línea:
https://cancerpreventionresearch.aacrjournals.org/content/11/9/581
http://hdl.handle.net/10554/51931
https://doi.org/10.1158/1940-6207.CAPR-17-0439
Palabra clave:
Rights
License
Atribución-NoComercial 4.0 Internacional
id JAVERIANA2_ecf79e61f454cc8aa2c557256c66b2bd
oai_identifier_str oai:repository.javeriana.edu.co:10554/51931
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network_name_str Repositorio Universidad Javeriana
repository_id_str
dc.title.spa.fl_str_mv Detection and genotyping of HPV DNA in a group of unvaccinated young women from Colombia : baseline measures prior to future monitoring program
title Detection and genotyping of HPV DNA in a group of unvaccinated young women from Colombia : baseline measures prior to future monitoring program
spellingShingle Detection and genotyping of HPV DNA in a group of unvaccinated young women from Colombia : baseline measures prior to future monitoring program
title_short Detection and genotyping of HPV DNA in a group of unvaccinated young women from Colombia : baseline measures prior to future monitoring program
title_full Detection and genotyping of HPV DNA in a group of unvaccinated young women from Colombia : baseline measures prior to future monitoring program
title_fullStr Detection and genotyping of HPV DNA in a group of unvaccinated young women from Colombia : baseline measures prior to future monitoring program
title_full_unstemmed Detection and genotyping of HPV DNA in a group of unvaccinated young women from Colombia : baseline measures prior to future monitoring program
title_sort Detection and genotyping of HPV DNA in a group of unvaccinated young women from Colombia : baseline measures prior to future monitoring program
dc.creator.fl_str_mv Puerto, Devi
Reyes, Viviana
Lozano, Cristina
Garcia, Diego
Muñoz, Nubia
Hernandez, Gustavo A.
Sanchez, Laura
Wiesner Ceballos, Carolina
Combita, Alba
dc.contributor.author.none.fl_str_mv Puerto, Devi
Reyes, Viviana
Lozano, Cristina
Garcia, Diego
Muñoz, Nubia
Hernandez, Gustavo A.
Sanchez, Laura
Wiesner Ceballos, Carolina
Combita, Alba
dc.contributor.corporatename.none.fl_str_mv Pontificia Universidad Javeriana. Facultad de Medicina. Departamento de Medicina Preventiva y Social. Grupo de investigación de Medicina Preventiva y Social
dc.contributor.javerianateacher.none.fl_str_mv Buitrago Ubaque, Lina Paola
Murillo, Raul
description Q2
publishDate 2018
dc.date.created.none.fl_str_mv 2018-07-10
dc.date.accessioned.none.fl_str_mv 2020-12-05T02:50:40Z
dc.date.available.none.fl_str_mv 2020-12-05T02:50:40Z
dc.type.local.spa.fl_str_mv Artículo de revista
dc.type.coar.spa.fl_str_mv http://purl.org/coar/resource_type/c_dcae04bc
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dc.identifier.spa.fl_str_mv https://cancerpreventionresearch.aacrjournals.org/content/11/9/581
dc.identifier.issn.spa.fl_str_mv 1940-6207 / 1940-6215 (Electrónico)
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/10554/51931
dc.identifier.doi.spa.fl_str_mv https://doi.org/10.1158/1940-6207.CAPR-17-0439
dc.identifier.instname.spa.fl_str_mv instname:Pontificia Universidad Javeriana
dc.identifier.reponame.spa.fl_str_mv reponame:Repositorio Institucional - Pontificia Universidad Javeriana
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url https://cancerpreventionresearch.aacrjournals.org/content/11/9/581
http://hdl.handle.net/10554/51931
https://doi.org/10.1158/1940-6207.CAPR-17-0439
identifier_str_mv 1940-6207 / 1940-6215 (Electrónico)
instname:Pontificia Universidad Javeriana
reponame:Repositorio Institucional - Pontificia Universidad Javeriana
repourl:https://repository.javeriana.edu.co
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.citationstartpage.spa.fl_str_mv 581
dc.relation.citationendpage.spa.fl_str_mv 592
dc.relation.ispartofjournal.spa.fl_str_mv Cancer Prevention Research
dc.relation.citationvolume.spa.fl_str_mv 11
dc.relation.citationissue.spa.fl_str_mv 9
dc.rights.licence.*.fl_str_mv Atribución-NoComercial 4.0 Internacional
dc.rights.uri.*.fl_str_mv http://creativecommons.org/licenses/by-nc/4.0/
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institution Pontificia Universidad Javeriana
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repository.name.fl_str_mv Repositorio Institucional - Pontificia Universidad Javeriana
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spelling Atribución-NoComercial 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc/4.0/http://purl.org/coar/access_right/c_abf2Puerto, DeviReyes, VivianaLozano, CristinaGarcia, DiegoMuñoz, NubiaHernandez, Gustavo A.Sanchez, LauraWiesner Ceballos, CarolinaCombita, AlbaPontificia Universidad Javeriana. Facultad de Medicina. Departamento de Medicina Preventiva y Social. Grupo de investigación de Medicina Preventiva y SocialBuitrago Ubaque, Lina PaolaMurillo, Raul2020-12-05T02:50:40Z2020-12-05T02:50:40Z2018-07-10https://cancerpreventionresearch.aacrjournals.org/content/11/9/5811940-6207 / 1940-6215 (Electrónico)http://hdl.handle.net/10554/51931https://doi.org/10.1158/1940-6207.CAPR-17-0439instname:Pontificia Universidad Javerianareponame:Repositorio Institucional - Pontificia Universidad Javerianarepourl:https://repository.javeriana.edu.coPDFapplication/pdfengDetection and genotyping of HPV DNA in a group of unvaccinated young women from Colombia : baseline measures prior to future monitoring programArtículo de revistahttp://purl.org/coar/resource_type/c_dcae04bcQ2Q1In 2012, Colombia launched human papillomavirus (HPV) vaccination program for girls ages 9 to 12, and in 2013, the target age was expanded to 9 to 17 years. Monitoring the changes of HPV infection prevalence among young women has been proposed as an endpoint for early assessment of HPV vaccination programs. However, the data on HPV prevalence in young ages are very limited. The purpose of this study was to determine the prevalence of HPV infection and the distribution of genotypes in a group of nonvaccinated women ages 18 to 25 years old in three Colombian cities as baseline for the monitoring of the HPV national vaccination program. A total of 1,782 sexually active women were included. Cervical smear samples were collected to perform the Pap smear and HPV DNA detection using a Linear Array HPV assay. Of the 1,782 specimens analyzed, 60.3% were positive for any HPV type; 42.2% were positive for highrisk HPV (HR-HVP) types, and 44.4% for low-risk HPV (LR-HPV) types. Multiple and single infections were identified in 37.1% and 23.2% of samples, respectively. HR-HPV types -16, -52, and -51 were the most predominant with proportions of 11.3%, 7.92%, and 7.9%, correspondingly. The prevalence for HR-HPV 16/18 was 14.4%. HR-HPV prevalence in women with abnormal cytology (75.16%) was higher than in women with normal cytology (38.6%). In conclusion, a high prevalence of HR-HPV was observed among younger women. This HPV typespecific prevalence baseline may be used to monitor postvaccination longitudinal changes and to determine its impact on HPV-related disease incidence in Colombia population.https://orcid.org/0000-0002-0610-6477https://orcid.org/0000-0001-7187-9946https://orcid.org/0000-0002-3373-1809https://orcid.org/0000-0001-6295-7316Revista Internacional - Indexada581592Cancer Prevention Research119ORIGINAL581.full.pdf581.full.pdfArtículoapplication/pdf771239http://repository.javeriana.edu.co/bitstream/10554/51931/1/581.full.pdf478ccc7377fcae70bf837af467a18a01MD51open accessLICENSElicense.txtlicense.txttext/plain; charset=utf-82603http://repository.javeriana.edu.co/bitstream/10554/51931/2/license.txt2070d280cc89439d983d9eee1b17df53MD52open accessTHUMBNAIL581.full.pdf.jpg581.full.pdf.jpgIM Thumbnailimage/jpeg13022http://repository.javeriana.edu.co/bitstream/10554/51931/3/581.full.pdf.jpg0de03bc1e0e516b3abc5725b98668869MD53open access10554/51931oai:repository.javeriana.edu.co:10554/519312020-12-28 03:03:23.683Repositorio Institucional - Pontificia Universidad Javerianarepositorio@javeriana.edu.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