Multicentric study of cervical cancer screening with human papillomavirus testing and assessment of triage methods in Latin America : the ESTAMPA screening study protocol

Q1

Autores:
Almonte, Maribel
Sánchez, Gloria Inés
González, Paula
Ferrera, Annabelle
Picconi, María Alejandra
Wiesner, Carolina
Cruz-Valdez, Aurelio
Lazcano-Ponce, Eduardo
Jerónimo, Jose
Ferreccio, Catterina
Kasamatsu, Elena
Mendoza, Laura
Rodríguez, Guillermo
Venegas, Gino
Villagra, Verónica
Tatti, Silvio
Fleider, Laura
Terán, Carolina
Baena, Armando
Hernández, María de la Luz
Rol, Mary Luz
Eric. Lucas
Barbier, Sylvaine
Ramírez, Arianis Tatiana
Arrossi, Silvina
Rodríguez, María Isabel
González, Emmanuel
Celis, Marcela
Martínez, Sandra
Salgado, Yuly
Ortega, Marina
Beracochea, Andrea Verónica
Pérez, Natalia
Rodríguez de la Peña, Margarita
Ramón, María
Hernández-Nevarez, Pilar
Arboleda-Naranjo, Margarita
Cabrera, Yessy
Salgado, Brenda
García, Laura
Retana, Marco Antonio
Colucci, María Celeste
Arias-Stella, Javier
Bellido-Fuentes, Yenny
Bobadilla, María Liz
Olmedo, Gladys
Brito-García, Ivone
Méndez-Herrera, Armando
Cardinal, Lucía
Flores, Betsy
Peñaranda, Jhacquelin
Martínez-Bette, Josefina
Soilán, Ana
Figueroa, Jacqueline
Caserta, Benedicta
Sosa, Carlos
Moreno, Adrián
Mural, Juan
Doimi, Franco
Giménez, Diana
Rodríguez, Hernando
Lora, Oscar
Luciani, Silvana
Broutet, Nathalie
Darragh, Teresa
Calderón, Alejandro
Tipo de recurso:
Article of data
Fecha de publicación:
2020
Institución:
Pontificia Universidad Javeriana
Repositorio:
Repositorio Universidad Javeriana
Idioma:
eng
OAI Identifier:
oai:repository.javeriana.edu.co:10554/51891
Acceso en línea:
https://bmjopen.bmj.com/content/10/5/e035796
http://hdl.handle.net/10554/51891
http://dx.doi.org/10.1136/bmjopen-2019-035796
Palabra clave:
Rights
License
Atribución-NoComercial 4.0 Internacional
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oai_identifier_str oai:repository.javeriana.edu.co:10554/51891
network_acronym_str JAVERIANA2
network_name_str Repositorio Universidad Javeriana
repository_id_str
dc.title.spa.fl_str_mv Multicentric study of cervical cancer screening with human papillomavirus testing and assessment of triage methods in Latin America : the ESTAMPA screening study protocol
title Multicentric study of cervical cancer screening with human papillomavirus testing and assessment of triage methods in Latin America : the ESTAMPA screening study protocol
spellingShingle Multicentric study of cervical cancer screening with human papillomavirus testing and assessment of triage methods in Latin America : the ESTAMPA screening study protocol
title_short Multicentric study of cervical cancer screening with human papillomavirus testing and assessment of triage methods in Latin America : the ESTAMPA screening study protocol
title_full Multicentric study of cervical cancer screening with human papillomavirus testing and assessment of triage methods in Latin America : the ESTAMPA screening study protocol
title_fullStr Multicentric study of cervical cancer screening with human papillomavirus testing and assessment of triage methods in Latin America : the ESTAMPA screening study protocol
title_full_unstemmed Multicentric study of cervical cancer screening with human papillomavirus testing and assessment of triage methods in Latin America : the ESTAMPA screening study protocol
title_sort Multicentric study of cervical cancer screening with human papillomavirus testing and assessment of triage methods in Latin America : the ESTAMPA screening study protocol
dc.creator.fl_str_mv Almonte, Maribel
Sánchez, Gloria Inés
González, Paula
Ferrera, Annabelle
Picconi, María Alejandra
Wiesner, Carolina
Cruz-Valdez, Aurelio
Lazcano-Ponce, Eduardo
Jerónimo, Jose
Ferreccio, Catterina
Kasamatsu, Elena
Mendoza, Laura
Rodríguez, Guillermo
Venegas, Gino
Villagra, Verónica
Tatti, Silvio
Fleider, Laura
Terán, Carolina
Baena, Armando
Hernández, María de la Luz
Rol, Mary Luz
Eric. Lucas
Barbier, Sylvaine
Ramírez, Arianis Tatiana
Arrossi, Silvina
Rodríguez, María Isabel
González, Emmanuel
Celis, Marcela
Martínez, Sandra
Salgado, Yuly
Ortega, Marina
Beracochea, Andrea Verónica
Pérez, Natalia
Rodríguez de la Peña, Margarita
Ramón, María
Hernández-Nevarez, Pilar
Arboleda-Naranjo, Margarita
Cabrera, Yessy
Salgado, Brenda
García, Laura
Retana, Marco Antonio
Colucci, María Celeste
Arias-Stella, Javier
Bellido-Fuentes, Yenny
Bobadilla, María Liz
Olmedo, Gladys
Brito-García, Ivone
Méndez-Herrera, Armando
Cardinal, Lucía
Flores, Betsy
Peñaranda, Jhacquelin
Martínez-Bette, Josefina
Soilán, Ana
Figueroa, Jacqueline
Caserta, Benedicta
Sosa, Carlos
Moreno, Adrián
Mural, Juan
Doimi, Franco
Giménez, Diana
Rodríguez, Hernando
Lora, Oscar
Luciani, Silvana
Broutet, Nathalie
Darragh, Teresa
Calderón, Alejandro
dc.contributor.author.none.fl_str_mv Almonte, Maribel
Sánchez, Gloria Inés
González, Paula
Ferrera, Annabelle
Picconi, María Alejandra
Wiesner, Carolina
Cruz-Valdez, Aurelio
Lazcano-Ponce, Eduardo
Jerónimo, Jose
Ferreccio, Catterina
Kasamatsu, Elena
Mendoza, Laura
Rodríguez, Guillermo
Venegas, Gino
Villagra, Verónica
Tatti, Silvio
Fleider, Laura
Terán, Carolina
Baena, Armando
Hernández, María de la Luz
Rol, Mary Luz
Eric. Lucas
Barbier, Sylvaine
Ramírez, Arianis Tatiana
Arrossi, Silvina
Rodríguez, María Isabel
González, Emmanuel
Celis, Marcela
Martínez, Sandra
Salgado, Yuly
Ortega, Marina
Beracochea, Andrea Verónica
Pérez, Natalia
Rodríguez de la Peña, Margarita
Ramón, María
Hernández-Nevarez, Pilar
Arboleda-Naranjo, Margarita
Cabrera, Yessy
Salgado, Brenda
García, Laura
Retana, Marco Antonio
Colucci, María Celeste
Arias-Stella, Javier
Bellido-Fuentes, Yenny
Bobadilla, María Liz
Olmedo, Gladys
Brito-García, Ivone
Méndez-Herrera, Armando
Cardinal, Lucía
Flores, Betsy
Peñaranda, Jhacquelin
Martínez-Bette, Josefina
Soilán, Ana
Figueroa, Jacqueline
Caserta, Benedicta
Sosa, Carlos
Moreno, Adrián
Mural, Juan
Doimi, Franco
Giménez, Diana
Rodríguez, Hernando
Lora, Oscar
Luciani, Silvana
Broutet, Nathalie
Darragh, Teresa
Calderón, Alejandro
dc.contributor.corporatename.none.fl_str_mv Pontificia Universidad Javeriana. Facultad de Medicina. Departamento de Medicina Preventiva y Social. Grupo de investigación de Medicina Preventiva y Social
dc.contributor.javerianateacher.none.fl_str_mv Murillo, Raul
Herrero, Rolando
description Q1
publishDate 2020
dc.date.accessioned.none.fl_str_mv 2020-12-03T17:13:27Z
dc.date.available.none.fl_str_mv 2020-12-03T17:13:27Z
dc.date.created.none.fl_str_mv 2020-04-03
dc.type.local.spa.fl_str_mv Artículo de revista
dc.type.coar.spa.fl_str_mv http://purl.org/coar/resource_type/c_beb9
format http://purl.org/coar/resource_type/c_beb9
dc.identifier.spa.fl_str_mv https://bmjopen.bmj.com/content/10/5/e035796
dc.identifier.issn.spa.fl_str_mv 2044-6055 (Electrónico)
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/10554/51891
dc.identifier.doi.spa.fl_str_mv http://dx.doi.org/10.1136/bmjopen-2019-035796
dc.identifier.instname.spa.fl_str_mv instname:Pontificia Universidad Javeriana
dc.identifier.reponame.spa.fl_str_mv reponame:Repositorio Institucional - Pontificia Universidad Javeriana
dc.identifier.repourl.spa.fl_str_mv repourl:https://repository.javeriana.edu.co
url https://bmjopen.bmj.com/content/10/5/e035796
http://hdl.handle.net/10554/51891
http://dx.doi.org/10.1136/bmjopen-2019-035796
identifier_str_mv 2044-6055 (Electrónico)
instname:Pontificia Universidad Javeriana
reponame:Repositorio Institucional - Pontificia Universidad Javeriana
repourl:https://repository.javeriana.edu.co
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.citationstartpage.spa.fl_str_mv 1
dc.relation.citationendpage.spa.fl_str_mv 14
dc.relation.ispartofjournal.spa.fl_str_mv BMJ Open
dc.relation.citationvolume.spa.fl_str_mv 10
dc.relation.citationissue.spa.fl_str_mv 5
dc.rights.licence.*.fl_str_mv Atribución-NoComercial 4.0 Internacional
dc.rights.uri.*.fl_str_mv http://creativecommons.org/licenses/by-nc/4.0/
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rights_invalid_str_mv Atribución-NoComercial 4.0 Internacional
http://creativecommons.org/licenses/by-nc/4.0/
http://purl.org/coar/access_right/c_abf2
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institution Pontificia Universidad Javeriana
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spelling Atribución-NoComercial 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc/4.0/http://purl.org/coar/access_right/c_abf2Almonte, MaribelSánchez, Gloria InésGonzález, PaulaFerrera, AnnabellePicconi, María AlejandraWiesner, CarolinaCruz-Valdez, AurelioLazcano-Ponce, EduardoJerónimo, JoseFerreccio, CatterinaKasamatsu, ElenaMendoza, LauraRodríguez, GuillermoVenegas, GinoVillagra, VerónicaTatti, SilvioFleider, LauraTerán, CarolinaBaena, ArmandoHernández, María de la LuzRol, Mary LuzEric. LucasBarbier, SylvaineRamírez, Arianis TatianaArrossi, SilvinaRodríguez, María IsabelGonzález, EmmanuelCelis, MarcelaMartínez, SandraSalgado, YulyOrtega, MarinaBeracochea, Andrea VerónicaPérez, NataliaRodríguez de la Peña, MargaritaRamón, MaríaHernández-Nevarez, PilarArboleda-Naranjo, MargaritaCabrera, YessySalgado, BrendaGarcía, LauraRetana, Marco AntonioColucci, María CelesteArias-Stella, JavierBellido-Fuentes, YennyBobadilla, María LizOlmedo, GladysBrito-García, IvoneMéndez-Herrera, ArmandoCardinal, LucíaFlores, BetsyPeñaranda, JhacquelinMartínez-Bette, JosefinaSoilán, AnaFigueroa, JacquelineCaserta, BenedictaSosa, CarlosMoreno, AdriánMural, JuanDoimi, FrancoGiménez, DianaRodríguez, HernandoLora, OscarLuciani, SilvanaBroutet, NathalieDarragh, TeresaCalderón, AlejandroPontificia Universidad Javeriana. Facultad de Medicina. Departamento de Medicina Preventiva y Social. Grupo de investigación de Medicina Preventiva y SocialMurillo, RaulHerrero, Rolando2020-12-03T17:13:27Z2020-12-03T17:13:27Z2020-04-03https://bmjopen.bmj.com/content/10/5/e0357962044-6055 (Electrónico)http://hdl.handle.net/10554/51891http://dx.doi.org/10.1136/bmjopen-2019-035796instname:Pontificia Universidad Javerianareponame:Repositorio Institucional - Pontificia Universidad Javerianarepourl:https://repository.javeriana.edu.coPDFapplication/pdfengMulticentric study of cervical cancer screening with human papillomavirus testing and assessment of triage methods in Latin America : the ESTAMPA screening study protocolArtículo de revistahttp://purl.org/coar/resource_type/c_beb9Q1Q1Introduction Human papillomavirus (HPV) testing is replacing cytology in primary screening. Its limited specificity demands using a second (triage) test to better identify women at high-risk of cervical disease. Cytology represents the immediate triage but its low sensitivity might hamper HPV testing sensitivity, particularly in low-income and middle-income countries (LMICs), where cytology performance has been suboptimal. The ESTAMPA (EStudio multicéntrico de TAMizaje y triaje de cáncer de cuello uterino con pruebas del virus del PApiloma humano; Spanish acronym) study will: (1) evaluate the performance of different triage techniques to detect cervical precancer and (2) inform on how to implement HPV-based screening programmes in LMIC. Methods and analysis Women aged 30–64 years are screened with HPV testing and Pap across 12 study centres in Latin America. Screened positives have colposcopy with biopsy and treatment of lesions. Women with no evident disease are recalled 18 months later for another HPV test; those HPV-positive undergo colposcopy with biopsy and treatment as needed. Biological specimens are collected in different visits for triage testing, which is not used for clinical management. The study outcome is histological high-grade squamous intraepithelial or worse lesions (HSIL+) under the lower anogenital squamous terminology. About 50 000 women will be screened and 500 HSIL+ cases detected (at initial and 18 months screening). Performance measures (sensitivity, specificity and predictive values) of triage techniques to detect HSIL+ will be estimated and compared with adjustment by age and study centre. Ethics and dissemination The study protocol has been approved by the Ethics Committee of the International Agency for Research on Cancer (IARC), of the Pan American Health Organisation (PAHO) and by those in each participating centre. A Data and Safety Monitoring Board (DSMB) has been established to monitor progress of the study, assure participant safety, advice on scientific conduct and analysis and suggest protocol improvements. Study findings will be published in peer-reviewed journals and presented at scientific meetings. Trial registration number NCT01881659Revista Internacional - Indexada114BMJ Open105ORIGINALe035796.full.pdfe035796.full.pdfArtículoapplication/pdf2400862http://repository.javeriana.edu.co/bitstream/10554/51891/1/e035796.full.pdf0c34b03c66a286b5a2adb6910527c56bMD51open accessLICENSElicense.txtlicense.txttext/plain; charset=utf-82603http://repository.javeriana.edu.co/bitstream/10554/51891/2/license.txt2070d280cc89439d983d9eee1b17df53MD52open accessTHUMBNAILe035796.full.pdf.jpge035796.full.pdf.jpgIM Thumbnailimage/jpeg15646http://repository.javeriana.edu.co/bitstream/10554/51891/3/e035796.full.pdf.jpge68fc9ec79216ad27fc6d92621b72037MD53open access10554/51891oai:repository.javeriana.edu.co:10554/518912020-12-27 03:03:51.196Repositorio Institucional - Pontificia Universidad Javerianarepositorio@javeriana.edu.coTElDRU5DSUEgWSBBVVRPUklaQUNJw5NOIERFIExPUyBBVVRPUkVTIFBBUkEgUFVCTElDQVIgWSBQRVJNSVRJUiBMQSBDT05TVUxUQSBZIFVTTy4KClBhcnRlIDEuIFTDqXJtaW5vcyBkZSBsYSBsaWNlbmNpYSBnZW5lcmFsIHBhcmEgcHVibGljYWNpw7NuIGRlIG9icmFzIGVuIGVsIHJlcG9zaXRvcmlvIGluc3RpdHVjaW9uYWwKQ29tbyB0aXR1bGFyIChlcykgZGVsIGRlcmVjaG8gZGUgYXV0b3IsIGNvbmZpZXJvIChlcmltb3MpIGEgbGEgUG9udGlmaWNpYSBVbml2ZXJzaWRhZCBKYXZlcmlhbmEgdW5hIGxpY2VuY2lhIG5vIGV4Y2x1c2l2YSwgbGltaXRhZGEgeSBncmF0dWl0YSBzb2JyZSBsYSBvYnJhIHF1ZSBzZSBpbnRlZ3JhcsOhIGVuIGVsIFJlcG9zaXRvcmlvIEluc3RpdHVjaW9uYWwsIHF1ZSBzZSBhanVzdGEgYSBsYXMgc2lndWllbnRlcyBjYXJhY3RlcsOtc3RpY2FzOgphKSAgICAgIEVzdGFyw6EgdmlnZW50ZSBhIHBhcnRpciBkZSBsYSBmZWNoYSBkZSBpbmNsdXNpw7NuIGVuIGVsIHJlcG9zaXRvcmlvLCBwb3IgdW4gcGxhem8gZGUgNSBhw7FvcywgcXVlIHNlcsOhbiBwcm9ycm9nYWJsZXMgaW5kZWZpbmlkYW1lbnRlIHBvciBlbCB0aWVtcG8gcXVlIGR1cmUgZWwgZGVyZWNobyBwYXRyaW1vbmlhbCBkZWwgYXV0b3IuIEVsIGF1dG9yIHBvZHLDoSBkYXIgcG9yIHRlcm1pbmFkYSBsYSBsaWNlbmNpYSBzb2xpY2l0w6FuZG9sbyBhIGxhIFVuaXZlcnNpZGFkIHBvciBlc2NyaXRvLgpiKSAgICAgIEF1dG9yaXphIGEgbGEgUG9udGlmaWNpYSBVbml2ZXJzaWRhZCBKYXZlcmlhbmEgYSBwdWJsaWNhciBsYSBvYnJhIGVuIGRpZ2l0YWwsIGNvbm9jaWVuZG8gcXVlLCBkYWRvIHF1ZSBzZSBwdWJsaWNhIGVuIEludGVybmV0LCBwb3IgZXN0ZSBoZWNobyBjaXJjdWxhIGNvbiB1biBhbGNhbmNlIG11bmRpYWwuCmMpICAgICAgTG9zIGF1dG9yZXMgYWNlcHRhbiBxdWUgbGEgYXV0b3JpemFjacOzbiBzZSBoYWNlIGEgdMOtdHVsbyBncmF0dWl0bywgcG9yIGxvIHRhbnRvIHJlbnVuY2lhbiBhIHJlY2liaXIgYmVuZWZpY2lvIGFsZ3VubyBwb3IgbGEgcHVibGljYWNpw7NuLCBkaXN0cmlidWNpw7NuLCBjb211bmljYWNpw7NuIHDDumJsaWNhIHkgY3VhbHF1aWVyIG90cm8gdXNvIHF1ZSBzZSBoYWdhIGVuIGxvcyB0w6lybWlub3MgZGUgbGEgcHJlc2VudGUgbGljZW5jaWEgeSBkZSBsYSBsaWNlbmNpYSBkZSB1c28gY29uIHF1ZSBzZSBwdWJsaWNhLgpkKSAgICAgIExvcyBhdXRvcmVzIG1hbmlmaWVzdGFuIHF1ZSBzZSB0cmF0YSBkZSB1bmEgb2JyYSBvcmlnaW5hbCBzb2JyZSBsYSBxdWUgdGllbmVuIGxvcyBkZXJlY2hvcyBxdWUgYXV0b3JpemFuIHkgcXVlIHNvbiBlbGxvcyBxdWllbmVzIGFzdW1lbiB0b3RhbCByZXNwb25zYWJpbGlkYWQgcG9yIGVsIGNvbnRlbmlkbyBkZSBzdSBvYnJhIGFudGUgbGEgUG9udGlmaWNpYSBVbml2ZXJzaWRhZCBKYXZlcmlhbmEgeSBhbnRlIHRlcmNlcm9zLiBFbiB0b2RvIGNhc28gbGEgUG9udGlmaWNpYSBVbml2ZXJzaWRhZCBKYXZlcmlhbmEgc2UgY29tcHJvbWV0ZSBhIGluZGljYXIgc2llbXByZSBsYSBhdXRvcsOtYSBpbmNsdXllbmRvIGVsIG5vbWJyZSBkZWwgYXV0b3IgeSBsYSBmZWNoYSBkZSBwdWJsaWNhY2nDs24uCmUpICAgICAgQXV0b3Jpem8gKGFtb3MpIGEgbGEgVW5pdmVyc2lkYWQgcGFyYSBpbmNsdWlyIGxhIG9icmEgZW4gbG9zIMOtbmRpY2VzIHkgYnVzY2Fkb3JlcyBxdWUgZXN0aW1lbiBuZWNlc2FyaW9zIHBhcmEgcHJvbW92ZXIgc3UgZGlmdXNpw7NuLgpmKSAgICAgIEFjZXB0byAoYW1vcykgcXVlIGxhIFBvbnRpZmljaWEgVW5pdmVyc2lkYWQgSmF2ZXJpYW5hIHB1ZWRhIGNvbnZlcnRpciBlbCBkb2N1bWVudG8gYSBjdWFscXVpZXIgbWVkaW8gbyBmb3JtYXRvIHBhcmEgcHJvcMOzc2l0b3MgZGUgcHJlc2VydmFjacOzbiBkaWdpdGFsLgpnKSAgICAgIEF1dG9yaXpvIChhbW9zKSBxdWUgbGEgb2JyYSBzZWEgcHVlc3RhIGEgZGlzcG9zaWNpw7NuIGRlbCBww7pibGljbyBlbiBsb3MgdMOpcm1pbm9zIGF1dG9yaXphZG9zIGVuIGxvcyBsaXRlcmFsZXMgYW50ZXJpb3JlcyBiYWpvIGxvcyBsw61taXRlcyBkZWZpbmlkb3MgcG9yIGxhIHVuaXZlcnNpZGFkIGVuIGxhcyDigJxDb25kaWNpb25lcyBkZSB1c28gZGUgZXN0cmljdG8gY3VtcGxpbWllbnRv4oCdIGRlIGxvcyByZWN1cnNvcyBwdWJsaWNhZG9zIGVuIFJlcG9zaXRvcmlvIEluc3RpdHVjaW9uYWwgUFVKICwgY3V5byB0ZXh0byBjb21wbGV0byBzZSBwdWVkZSBjb25zdWx0YXIgZW4gaHR0cDovL3JlcG9zaXRvcnkuamF2ZXJpYW5hLmVkdS5jby8KClNJIEVMIERPQ1VNRU5UTyBTRSBCQVNBIEVOIFVOIFRSQUJBSk8gUVVFIEhBIFNJRE8gUEFUUk9DSU5BRE8gTyBBUE9ZQURPIFBPUiBVTkEgQUdFTkNJQSBPIFVOQSBPUkdBTklaQUNJw5NOLCBDT04gRVhDRVBDScOTTiBERSBMQSBQT05USUZJQ0lBIFVOSVZFUlNJREFEIEpBVkVSSUFOQSwgRUwgKExPUykgQVVUT1IoRVMpIEdBUkFOVElaQShNT1MpIFFVRSBTRSBIQSBDVU1QTElETyBDT04gTE9TIERFUkVDSE9TIFkgT0JMSUdBQ0lPTkVTIFJFUVVFUklET1MgUE9SIEVMIFJFU1BFQ1RJVk8gQ09OVFJBVE8gTyBBQ1VFUkRPLgo=