Efficacy and safety of sensor augmented insulin pump therapy withlow-glucose suspend feature in older adults : a retrospective study in Bogota, Colombia
Q2
- Autores:
-
Morros-González, Elly
Gómez, Ana María
Henao Carrillo, Diana Cristina
Ursida, Valentina
Serrano, Sergio
Rondón Sepúlveda, Martín Alonso
Muñoz Velandia, Oscar Mauricio
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2021
- Institución:
- Pontificia Universidad Javeriana
- Repositorio:
- Repositorio Universidad Javeriana
- Idioma:
- eng
- OAI Identifier:
- oai:repository.javeriana.edu.co:10554/55036
- Acceso en línea:
- https://login.ezproxy.javeriana.edu.co/login?url=https://search.ebscohost.com/login.aspx?direct=true&db=edselp&AN=S187140212100059X&lang=es&site=eds-live
http://hdl.handle.net/10554/55036
https://doi.org/10.1016/j.dsx.2021.02.029
- Palabra clave:
- Sensor augmented insulin pump therapy
Low-glucose suspend function
Continuous subcutaneous insulin infusion
Hypoglycemia
Aged
Elderly
- Rights
- License
- Atribución-NoComercial 4.0 Internacional
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| dc.title.spa.fl_str_mv |
Efficacy and safety of sensor augmented insulin pump therapy withlow-glucose suspend feature in older adults : a retrospective study in Bogota, Colombia |
| title |
Efficacy and safety of sensor augmented insulin pump therapy withlow-glucose suspend feature in older adults : a retrospective study in Bogota, Colombia |
| spellingShingle |
Efficacy and safety of sensor augmented insulin pump therapy withlow-glucose suspend feature in older adults : a retrospective study in Bogota, Colombia Sensor augmented insulin pump therapy Low-glucose suspend function Continuous subcutaneous insulin infusion Hypoglycemia Aged Elderly |
| title_short |
Efficacy and safety of sensor augmented insulin pump therapy withlow-glucose suspend feature in older adults : a retrospective study in Bogota, Colombia |
| title_full |
Efficacy and safety of sensor augmented insulin pump therapy withlow-glucose suspend feature in older adults : a retrospective study in Bogota, Colombia |
| title_fullStr |
Efficacy and safety of sensor augmented insulin pump therapy withlow-glucose suspend feature in older adults : a retrospective study in Bogota, Colombia |
| title_full_unstemmed |
Efficacy and safety of sensor augmented insulin pump therapy withlow-glucose suspend feature in older adults : a retrospective study in Bogota, Colombia |
| title_sort |
Efficacy and safety of sensor augmented insulin pump therapy withlow-glucose suspend feature in older adults : a retrospective study in Bogota, Colombia |
| dc.creator.fl_str_mv |
Morros-González, Elly Gómez, Ana María Henao Carrillo, Diana Cristina Ursida, Valentina Serrano, Sergio Rondón Sepúlveda, Martín Alonso Muñoz Velandia, Oscar Mauricio |
| dc.contributor.author.none.fl_str_mv |
Morros-González, Elly Gómez, Ana María Henao Carrillo, Diana Cristina Ursida, Valentina Serrano, Sergio Rondón Sepúlveda, Martín Alonso Muñoz Velandia, Oscar Mauricio |
| dc.contributor.corporatename.spa.fl_str_mv |
Pontificia Universidad Javeriana. Facultad de Medicina. Instituto de Envejecimiento |
| dc.contributor.corporatename.none.fl_str_mv |
Pontificia Universidad Javeriana. Facultad de Medicina. Departamento de Medicina Interna. Medicina Interna |
| dc.subject.keyword.spa.fl_str_mv |
Sensor augmented insulin pump therapy Low-glucose suspend function Continuous subcutaneous insulin infusion Hypoglycemia Aged Elderly |
| topic |
Sensor augmented insulin pump therapy Low-glucose suspend function Continuous subcutaneous insulin infusion Hypoglycemia Aged Elderly |
| description |
Q2 |
| publishDate |
2021 |
| dc.date.accessioned.none.fl_str_mv |
2021-07-16T02:56:57Z |
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2021-07-16T02:56:57Z |
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2021 |
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Artículo de revista |
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1871-4021 |
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http://hdl.handle.net/10554/55036 |
| dc.identifier.doi.spa.fl_str_mv |
https://doi.org/10.1016/j.dsx.2021.02.029 |
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eng |
| language |
eng |
| dc.relation.citationstartpage.spa.fl_str_mv |
649 |
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653 |
| dc.relation.ispartofjournal.spa.fl_str_mv |
Diabetes & Metabolic Syndrome : Clinical Research & Reviews |
| dc.relation.citationvolume.spa.fl_str_mv |
15 |
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Atribución-NoComercial 4.0 Internacional |
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PDF |
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application/pdf |
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Colombia |
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Bogotá (Colombia) |
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Pontificia Universidad Javeriana |
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Atribución-NoComercial 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc/4.0/http://purl.org/coar/access_right/c_abf2Morros-González, EllyGómez, Ana MaríaHenao Carrillo, Diana CristinaUrsida, ValentinaSerrano, SergioRondón Sepúlveda, Martín AlonsoMuñoz Velandia, Oscar MauricioPontificia Universidad Javeriana. Facultad de Medicina. Instituto de EnvejecimientoPontificia Universidad Javeriana. Facultad de Medicina. Departamento de Medicina Interna. Medicina InternaColombiaBogotá (Colombia)2021-07-16T02:56:57Z2021-07-16T02:56:57Z2021https://login.ezproxy.javeriana.edu.co/login?url=https://search.ebscohost.com/login.aspx?direct=true&db=edselp&AN=S187140212100059X&lang=es&site=eds-live1871-4021http://hdl.handle.net/10554/55036https://doi.org/10.1016/j.dsx.2021.02.029instname:Pontificia Universidad Javerianareponame:Repositorio Institucional - Pontificia Universidad Javerianarepourl:https://repository.javeriana.edu.coPDFapplication/pdfengEfficacy and safety of sensor augmented insulin pump therapy withlow-glucose suspend feature in older adults : a retrospective study in Bogota, ColombiaArtículo de revistahttp://purl.org/coar/resource_type/c_2df8fbb1Q2Background and aims:The literature has supported the efficacy and safety of insulin pump therapy inyoung adults diagnosed with type 1 diabetes (DM1). However, there is limited evidence in older adultswith DM1 and DM2.Methods:A retrospective cohort study was conducted in patients≥60 years-old with DM1 and DM2,who started Sensor Augmented Insulin Pump therapy with low-glucose suspend feature (SAPþLGS) atHospital Universitario San Ignacio diabetes center in Bogotá, Colombia. Patients were evaluated between2009 and 2019 and were treated with Paradigm VEO or Medtronic MiniMed 640 insulin pumps andcontinuous glucose monitoring system. Glycated hemoglobin (A1c), severe hypoglycemia and hypogly-cemia unawareness were assessed at least every 3 months, and hospitalizations and ketoacidosis epi-sodes incidence were assessed yearly.Results:36 patients were analyzed, (67.36±4.88 years-old) (body mass index 25.48±4.61 kg/m2). Themost common indications for starting SAPþLGS were hypoglycemia (58.3%), high glycemic variability(25.0%) and poor metabolic control (16.7%). 26 patients used VEO (72.2%) whereas 27.8% started 640insulin pump. Data from 32 participants showed A1c decreased from 8.57±1.73% to 7.42±0.96 after ayear of therapy (Mean difference 1.15%, p<0.05); 28.12% reached A1c levels<7% and 42.85%<7.5%.There was a significant decrease in the proportion of patients with at least one severe hypoglycemia (56.7vs 3.3%), one or more hospitalizations (20 vs 3.3%), and hypoglycemia unawareness after thefirst year offollow-up (p<0.05).Conclusions:These results suggest that SAPþLGS is safe and effective in people 60 years or older afterone year of therapy. Future randomized clinical trials are needed in the elderly.https://orcid.org/0000-0002-7946-3379https://orcid.org/0000-0002-1353-148Xhttps://orcid.org/0000-0002-1353-148Xhttps://orcid.org/0000-0002-3885-5448https://orcid.org/0000-0001-5401-0018Revista Internacional - IndexadaSensor augmented insulin pump therapyLow-glucose suspend functionContinuous subcutaneous insulin infusionHypoglycemiaAgedElderly649653Diabetes & Metabolic Syndrome : Clinical Research & Reviews15LICENSElicense.txtlicense.txttext/plain; charset=utf-82603http://repository.javeriana.edu.co/bitstream/10554/55036/2/license.txt2070d280cc89439d983d9eee1b17df53MD52open accessORIGINALEfficacy and safety of sensor augmented insulin pump therapy older adults.pdfEfficacy and safety of sensor augmented insulin pump therapy older adults.pdfArtículoapplication/pdf333125http://repository.javeriana.edu.co/bitstream/10554/55036/1/Efficacy%20and%20safety%20of%20sensor%20augmented%20insulin%20pump%20therapy%20older%20adults.pdffffeb56ead9ec6b644f04e694572230bMD51embargoed access|||9999-12-31THUMBNAILEfficacy and safety of sensor augmented insulin pump therapy older adults.pdf.jpgEfficacy and safety of sensor augmented insulin pump therapy older adults.pdf.jpgIM Thumbnailimage/jpeg9753http://repository.javeriana.edu.co/bitstream/10554/55036/3/Efficacy%20and%20safety%20of%20sensor%20augmented%20insulin%20pump%20therapy%20older%20adults.pdf.jpg083f508d223347bffb0bef825af1bb79MD53open access10554/55036oai:repository.javeriana.edu.co:10554/550362022-01-20 10:01:26.935Repositorio Institucional - Pontificia Universidad Javerianarepositorio@javeriana.edu.coTElDRU5DSUEgWSBBVVRPUklaQUNJw5NOIERFIExPUyBBVVRPUkVTIFBBUkEgUFVCTElDQVIgWSBQRVJNSVRJUiBMQSBDT05TVUxUQSBZIFVTTy4KClBhcnRlIDEuIFTDqXJtaW5vcyBkZSBsYSBsaWNlbmNpYSBnZW5lcmFsIHBhcmEgcHVibGljYWNpw7NuIGRlIG9icmFzIGVuIGVsIHJlcG9zaXRvcmlvIGluc3RpdHVjaW9uYWwKQ29tbyB0aXR1bGFyIChlcykgZGVsIGRlcmVjaG8gZGUgYXV0b3IsIGNvbmZpZXJvIChlcmltb3MpIGEgbGEgUG9udGlmaWNpYSBVbml2ZXJzaWRhZCBKYXZlcmlhbmEgdW5hIGxpY2VuY2lhIG5vIGV4Y2x1c2l2YSwgbGltaXRhZGEgeSBncmF0dWl0YSBzb2JyZSBsYSBvYnJhIHF1ZSBzZSBpbnRlZ3JhcsOhIGVuIGVsIFJlcG9zaXRvcmlvIEluc3RpdHVjaW9uYWwsIHF1ZSBzZSBhanVzdGEgYSBsYXMgc2lndWllbnRlcyBjYXJhY3RlcsOtc3RpY2FzOgphKSAgICAgIEVzdGFyw6EgdmlnZW50ZSBhIHBhcnRpciBkZSBsYSBmZWNoYSBkZSBpbmNsdXNpw7NuIGVuIGVsIHJlcG9zaXRvcmlvLCBwb3IgdW4gcGxhem8gZGUgNSBhw7FvcywgcXVlIHNlcsOhbiBwcm9ycm9nYWJsZXMgaW5kZWZpbmlkYW1lbnRlIHBvciBlbCB0aWVtcG8gcXVlIGR1cmUgZWwgZGVyZWNobyBwYXRyaW1vbmlhbCBkZWwgYXV0b3IuIEVsIGF1dG9yIHBvZHLDoSBkYXIgcG9yIHRlcm1pbmFkYSBsYSBsaWNlbmNpYSBzb2xpY2l0w6FuZG9sbyBhIGxhIFVuaXZlcnNpZGFkIHBvciBlc2NyaXRvLgpiKSAgICAgIEF1dG9yaXphIGEgbGEgUG9udGlmaWNpYSBVbml2ZXJzaWRhZCBKYXZlcmlhbmEgYSBwdWJsaWNhciBsYSBvYnJhIGVuIGRpZ2l0YWwsIGNvbm9jaWVuZG8gcXVlLCBkYWRvIHF1ZSBzZSBwdWJsaWNhIGVuIEludGVybmV0LCBwb3IgZXN0ZSBoZWNobyBjaXJjdWxhIGNvbiB1biBhbGNhbmNlIG11bmRpYWwuCmMpICAgICAgTG9zIGF1dG9yZXMgYWNlcHRhbiBxdWUgbGEgYXV0b3JpemFjacOzbiBzZSBoYWNlIGEgdMOtdHVsbyBncmF0dWl0bywgcG9yIGxvIHRhbnRvIHJlbnVuY2lhbiBhIHJlY2liaXIgYmVuZWZpY2lvIGFsZ3VubyBwb3IgbGEgcHVibGljYWNpw7NuLCBkaXN0cmlidWNpw7NuLCBjb211bmljYWNpw7NuIHDDumJsaWNhIHkgY3VhbHF1aWVyIG90cm8gdXNvIHF1ZSBzZSBoYWdhIGVuIGxvcyB0w6lybWlub3MgZGUgbGEgcHJlc2VudGUgbGljZW5jaWEgeSBkZSBsYSBsaWNlbmNpYSBkZSB1c28gY29uIHF1ZSBzZSBwdWJsaWNhLgpkKSAgICAgIExvcyBhdXRvcmVzIG1hbmlmaWVzdGFuIHF1ZSBzZSB0cmF0YSBkZSB1bmEgb2JyYSBvcmlnaW5hbCBzb2JyZSBsYSBxdWUgdGllbmVuIGxvcyBkZXJlY2hvcyBxdWUgYXV0b3JpemFuIHkgcXVlIHNvbiBlbGxvcyBxdWllbmVzIGFzdW1lbiB0b3RhbCByZXNwb25zYWJpbGlkYWQgcG9yIGVsIGNvbnRlbmlkbyBkZSBzdSBvYnJhIGFudGUgbGEgUG9udGlmaWNpYSBVbml2ZXJzaWRhZCBKYXZlcmlhbmEgeSBhbnRlIHRlcmNlcm9zLiBFbiB0b2RvIGNhc28gbGEgUG9udGlmaWNpYSBVbml2ZXJzaWRhZCBKYXZlcmlhbmEgc2UgY29tcHJvbWV0ZSBhIGluZGljYXIgc2llbXByZSBsYSBhdXRvcsOtYSBpbmNsdXllbmRvIGVsIG5vbWJyZSBkZWwgYXV0b3IgeSBsYSBmZWNoYSBkZSBwdWJsaWNhY2nDs24uCmUpICAgICAgQXV0b3Jpem8gKGFtb3MpIGEgbGEgVW5pdmVyc2lkYWQgcGFyYSBpbmNsdWlyIGxhIG9icmEgZW4gbG9zIMOtbmRpY2VzIHkgYnVzY2Fkb3JlcyBxdWUgZXN0aW1lbiBuZWNlc2FyaW9zIHBhcmEgcHJvbW92ZXIgc3UgZGlmdXNpw7NuLgpmKSAgICAgIEFjZXB0byAoYW1vcykgcXVlIGxhIFBvbnRpZmljaWEgVW5pdmVyc2lkYWQgSmF2ZXJpYW5hIHB1ZWRhIGNvbnZlcnRpciBlbCBkb2N1bWVudG8gYSBjdWFscXVpZXIgbWVkaW8gbyBmb3JtYXRvIHBhcmEgcHJvcMOzc2l0b3MgZGUgcHJlc2VydmFjacOzbiBkaWdpdGFsLgpnKSAgICAgIEF1dG9yaXpvIChhbW9zKSBxdWUgbGEgb2JyYSBzZWEgcHVlc3RhIGEgZGlzcG9zaWNpw7NuIGRlbCBww7pibGljbyBlbiBsb3MgdMOpcm1pbm9zIGF1dG9yaXphZG9zIGVuIGxvcyBsaXRlcmFsZXMgYW50ZXJpb3JlcyBiYWpvIGxvcyBsw61taXRlcyBkZWZpbmlkb3MgcG9yIGxhIHVuaXZlcnNpZGFkIGVuIGxhcyDigJxDb25kaWNpb25lcyBkZSB1c28gZGUgZXN0cmljdG8gY3VtcGxpbWllbnRv4oCdIGRlIGxvcyByZWN1cnNvcyBwdWJsaWNhZG9zIGVuIFJlcG9zaXRvcmlvIEluc3RpdHVjaW9uYWwgUFVKICwgY3V5byB0ZXh0byBjb21wbGV0byBzZSBwdWVkZSBjb25zdWx0YXIgZW4gaHR0cDovL3JlcG9zaXRvcnkuamF2ZXJpYW5hLmVkdS5jby8KClNJIEVMIERPQ1VNRU5UTyBTRSBCQVNBIEVOIFVOIFRSQUJBSk8gUVVFIEhBIFNJRE8gUEFUUk9DSU5BRE8gTyBBUE9ZQURPIFBPUiBVTkEgQUdFTkNJQSBPIFVOQSBPUkdBTklaQUNJw5NOLCBDT04gRVhDRVBDScOTTiBERSBMQSBQT05USUZJQ0lBIFVOSVZFUlNJREFEIEpBVkVSSUFOQSwgRUwgKExPUykgQVVUT1IoRVMpIEdBUkFOVElaQShNT1MpIFFVRSBTRSBIQSBDVU1QTElETyBDT04gTE9TIERFUkVDSE9TIFkgT0JMSUdBQ0lPTkVTIFJFUVVFUklET1MgUE9SIEVMIFJFU1BFQ1RJVk8gQ09OVFJBVE8gTyBBQ1VFUkRPLgo= |