Relative handgrip strength diminishes the negative effects of excess adiposity on dependence in older adults : a moderation analysis

Q1

Autores:
Ramírez-Vélez, Robinson
Pérez-Sousa, Miguel Ángel
García-Hermoso, Antonio
Zambom-Ferraresi, Fabrício
Martínez-Velilla, Nicolás
Sáez de Asteasu, Mikel L.
Cano-Gutierrez, Carlos
Rincón-Pabón, David
Izquierdo, Mikel
Tipo de recurso:
Article of investigation
Fecha de publicación:
2020
Institución:
Pontificia Universidad Javeriana
Repositorio:
Repositorio Universidad Javeriana
Idioma:
eng
OAI Identifier:
oai:repository.javeriana.edu.co:10554/53615
Acceso en línea:
https://www.mdpi.com/2077-0383/9/4/1152/htm
http://hdl.handle.net/10554/53615
https://doi.org/10.3390/jcm9041152
Palabra clave:
Fat mass
Obesity
Muscle strength
Physical function
Functional dependence
Rights
License
Atribución-NoComercial 4.0 Internacional
id JAVERIANA2_9d746a865c8426120e659e51f82119c6
oai_identifier_str oai:repository.javeriana.edu.co:10554/53615
network_acronym_str JAVERIANA2
network_name_str Repositorio Universidad Javeriana
repository_id_str
dc.title.spa.fl_str_mv Relative handgrip strength diminishes the negative effects of excess adiposity on dependence in older adults : a moderation analysis
title Relative handgrip strength diminishes the negative effects of excess adiposity on dependence in older adults : a moderation analysis
spellingShingle Relative handgrip strength diminishes the negative effects of excess adiposity on dependence in older adults : a moderation analysis
Fat mass
Obesity
Muscle strength
Physical function
Functional dependence
title_short Relative handgrip strength diminishes the negative effects of excess adiposity on dependence in older adults : a moderation analysis
title_full Relative handgrip strength diminishes the negative effects of excess adiposity on dependence in older adults : a moderation analysis
title_fullStr Relative handgrip strength diminishes the negative effects of excess adiposity on dependence in older adults : a moderation analysis
title_full_unstemmed Relative handgrip strength diminishes the negative effects of excess adiposity on dependence in older adults : a moderation analysis
title_sort Relative handgrip strength diminishes the negative effects of excess adiposity on dependence in older adults : a moderation analysis
dc.creator.fl_str_mv Ramírez-Vélez, Robinson
Pérez-Sousa, Miguel Ángel
García-Hermoso, Antonio
Zambom-Ferraresi, Fabrício
Martínez-Velilla, Nicolás
Sáez de Asteasu, Mikel L.
Cano-Gutierrez, Carlos
Rincón-Pabón, David
Izquierdo, Mikel
dc.contributor.author.none.fl_str_mv Ramírez-Vélez, Robinson
Pérez-Sousa, Miguel Ángel
García-Hermoso, Antonio
Zambom-Ferraresi, Fabrício
Martínez-Velilla, Nicolás
Sáez de Asteasu, Mikel L.
Cano-Gutierrez, Carlos
Rincón-Pabón, David
Izquierdo, Mikel
dc.contributor.corporatename.none.fl_str_mv Pontificia Universidad Javeriana. Facultad de Medicina. Instituto de Envejecimiento
dc.subject.keyword.spa.fl_str_mv Fat mass
Obesity
Muscle strength
Physical function
Functional dependence
topic Fat mass
Obesity
Muscle strength
Physical function
Functional dependence
description Q1
publishDate 2020
dc.date.created.none.fl_str_mv 2020-04-08
dc.date.accessioned.none.fl_str_mv 2021-04-19T18:52:36Z
dc.date.available.none.fl_str_mv 2021-04-19T18:52:36Z
dc.type.local.spa.fl_str_mv Artículo de revista
dc.type.coar.spa.fl_str_mv http://purl.org/coar/resource_type/c_2df8fbb1
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dc.identifier.spa.fl_str_mv https://www.mdpi.com/2077-0383/9/4/1152/htm
dc.identifier.issn.spa.fl_str_mv 2077-0383
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/10554/53615
dc.identifier.doi.spa.fl_str_mv https://doi.org/10.3390/jcm9041152
dc.identifier.instname.spa.fl_str_mv instname:Pontificia Universidad Javeriana
dc.identifier.reponame.spa.fl_str_mv reponame:Repositorio Institucional - Pontificia Universidad Javeriana
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url https://www.mdpi.com/2077-0383/9/4/1152/htm
http://hdl.handle.net/10554/53615
https://doi.org/10.3390/jcm9041152
identifier_str_mv 2077-0383
instname:Pontificia Universidad Javeriana
reponame:Repositorio Institucional - Pontificia Universidad Javeriana
repourl:https://repository.javeriana.edu.co
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.ispartofjournal.spa.fl_str_mv Journal of Clinical Medicine
dc.relation.citationvolume.spa.fl_str_mv 9
dc.relation.citationissue.spa.fl_str_mv 4
dc.rights.licence.*.fl_str_mv Atribución-NoComercial 4.0 Internacional
dc.rights.uri.*.fl_str_mv http://creativecommons.org/licenses/by-nc/4.0/
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rights_invalid_str_mv Atribución-NoComercial 4.0 Internacional
http://creativecommons.org/licenses/by-nc/4.0/
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institution Pontificia Universidad Javeriana
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spelling Atribución-NoComercial 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc/4.0/http://purl.org/coar/access_right/c_abf2Ramírez-Vélez, RobinsonPérez-Sousa, Miguel ÁngelGarcía-Hermoso, AntonioZambom-Ferraresi, FabrícioMartínez-Velilla, NicolásSáez de Asteasu, Mikel L.Cano-Gutierrez, CarlosRincón-Pabón, DavidIzquierdo, MikelPontificia Universidad Javeriana. Facultad de Medicina. Instituto de Envejecimiento2021-04-19T18:52:36Z2021-04-19T18:52:36Z2020-04-08https://www.mdpi.com/2077-0383/9/4/1152/htm2077-0383http://hdl.handle.net/10554/53615https://doi.org/10.3390/jcm9041152instname:Pontificia Universidad Javerianareponame:Repositorio Institucional - Pontificia Universidad Javerianarepourl:https://repository.javeriana.edu.coPDFapplication/pdfengRelative handgrip strength diminishes the negative effects of excess adiposity on dependence in older adults : a moderation analysisArtículo de revistahttp://purl.org/coar/resource_type/c_2df8fbb1Q1Adultos mayoresThe adverse effects of fat mass on functional dependence might be attenuated or worsened, depending on the level of muscular strength. The aim of this study was to determine (i) the detrimental effect of excess adiposity on dependence in activities of daily living (ADL), and (ii) whether relative handgrip strength (HGS) moderates the adverse effect of excess adiposity on dependence, and to provide the threshold of relative HGS from which the adverse effect could be improved or worsened. A total of 4169 participants (69.3 ± 7.0 years old) from 244 municipalities were selected following a multistage area probability sampling design. Measurements included anthropometric/adiposity markers (weight, height, body mass index, waist circumference, and waist-to-height ratio (WHtR)), HGS, sarcopenia “proxy” (calf circumference), and ADL (Barthel Index scale). Moderation analyses were performed to identify associations between the independent variable (WHtR) and outcomes (dependence), as well as to determine whether relative HGS moderates the relationship between excess adiposity and dependence. The present study demonstrated that (i) the adverse effect of having a higher WHtR level on dependence in ADL was moderated by relative HGS, and (ii) two moderation thresholds of relative HGS were estimated: 0.35, below which the adverse effect of WHtR levels on dependency is aggravated, and 0.62, above which the adverse effect of fat on dependency could be improved. Because muscular strength represents a critically important and modifiable predictor of ADL, and the increase in adiposity is inherent in aging, our results underscore the importance of an optimal level of relative HGS in the older adult population.Revista Internacional - IndexadaFat massObesityMuscle strengthPhysical functionFunctional dependenceJournal of Clinical Medicine94ORIGINALRELATIVE HANDGRIP STRNGTH.pdfRELATIVE HANDGRIP STRNGTH.pdfArtículoapplication/pdf911454http://repository.javeriana.edu.co/bitstream/10554/53615/1/RELATIVE%20HANDGRIP%20STRNGTH.pdf7c7b8c04985d8fadf754717030a63f05MD51open accessLICENSElicense.txtlicense.txttext/plain; charset=utf-82603http://repository.javeriana.edu.co/bitstream/10554/53615/2/license.txt2070d280cc89439d983d9eee1b17df53MD52open accessTHUMBNAILRELATIVE HANDGRIP STRNGTH.pdf.jpgRELATIVE HANDGRIP STRNGTH.pdf.jpgIM Thumbnailimage/jpeg11380http://repository.javeriana.edu.co/bitstream/10554/53615/3/RELATIVE%20HANDGRIP%20STRNGTH.pdf.jpg7b3ff96288696d7d258e267885749d79MD53open access10554/53615oai:repository.javeriana.edu.co:10554/536152021-07-14 16:33:06.398Repositorio Institucional - Pontificia Universidad Javerianarepositorio@javeriana.edu.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