Role of VEGF in the differential growth between the fetal and placental ends of the umbilical cord
Q3
- Autores:
-
Olaya C, Mercedes
Michael, F
G, Fabian
Silva, J Luis
Garzon, A L
Bernal, J E
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2019
- Institución:
- Pontificia Universidad Javeriana
- Repositorio:
- Repositorio Universidad Javeriana
- Idioma:
- eng
- OAI Identifier:
- oai:repository.javeriana.edu.co:10554/53316
- Acceso en línea:
- https://login.ezproxy.javeriana.edu.co/login?url=https://search.ebscohost.com/login.aspx?direct=true&db=edselc&AN=edselc.2-52.0-85064122819&lang=es&site=eds-live
http://hdl.handle.net/10554/53316
https://doi.org/10.3233/NPM-1795
- Palabra clave:
- Umbilical cord
VEGF
Stillbirth
Umbilical cord length
- Rights
- License
- Atribución-NoComercial 4.0 Internacional
| id |
JAVERIANA2_9b6ee5d9a1e8d8626788f61874527fdc |
|---|---|
| oai_identifier_str |
oai:repository.javeriana.edu.co:10554/53316 |
| network_acronym_str |
JAVERIANA2 |
| network_name_str |
Repositorio Universidad Javeriana |
| repository_id_str |
|
| dc.title.spa.fl_str_mv |
Role of VEGF in the differential growth between the fetal and placental ends of the umbilical cord |
| title |
Role of VEGF in the differential growth between the fetal and placental ends of the umbilical cord |
| spellingShingle |
Role of VEGF in the differential growth between the fetal and placental ends of the umbilical cord Umbilical cord VEGF Stillbirth Umbilical cord length |
| title_short |
Role of VEGF in the differential growth between the fetal and placental ends of the umbilical cord |
| title_full |
Role of VEGF in the differential growth between the fetal and placental ends of the umbilical cord |
| title_fullStr |
Role of VEGF in the differential growth between the fetal and placental ends of the umbilical cord |
| title_full_unstemmed |
Role of VEGF in the differential growth between the fetal and placental ends of the umbilical cord |
| title_sort |
Role of VEGF in the differential growth between the fetal and placental ends of the umbilical cord |
| dc.creator.fl_str_mv |
Olaya C, Mercedes Michael, F G, Fabian Silva, J Luis Garzon, A L Bernal, J E |
| dc.contributor.author.none.fl_str_mv |
Olaya C, Mercedes Michael, F G, Fabian Silva, J Luis Garzon, A L Bernal, J E |
| dc.contributor.corporatename.none.fl_str_mv |
Pontificia Universidad Javeriana. Facultad de Medicina. Departamento de Patología Research Seedbed in Perinatal Medicine Pontificia Universidad Javeriana |
| dc.subject.keyword.spa.fl_str_mv |
Umbilical cord VEGF Stillbirth Umbilical cord length |
| topic |
Umbilical cord VEGF Stillbirth Umbilical cord length |
| description |
Q3 |
| publishDate |
2019 |
| dc.date.created.none.fl_str_mv |
2019 |
| dc.date.accessioned.none.fl_str_mv |
2021-03-23T15:40:03Z |
| dc.date.available.none.fl_str_mv |
2021-03-23T15:40:03Z |
| dc.type.local.spa.fl_str_mv |
Artículo de revista |
| dc.type.coar.spa.fl_str_mv |
http://purl.org/coar/resource_type/c_6501 |
| format |
http://purl.org/coar/resource_type/c_6501 |
| dc.identifier.spa.fl_str_mv |
https://login.ezproxy.javeriana.edu.co/login?url=https://search.ebscohost.com/login.aspx?direct=true&db=edselc&AN=edselc.2-52.0-85064122819&lang=es&site=eds-live |
| dc.identifier.issn.spa.fl_str_mv |
1934-5798 |
| dc.identifier.uri.none.fl_str_mv |
http://hdl.handle.net/10554/53316 |
| dc.identifier.doi.spa.fl_str_mv |
https://doi.org/10.3233/NPM-1795 |
| dc.identifier.instname.spa.fl_str_mv |
instname:Pontificia Universidad Javeriana |
| dc.identifier.reponame.spa.fl_str_mv |
reponame:Repositorio Institucional - Pontificia Universidad Javeriana |
| dc.identifier.repourl.spa.fl_str_mv |
repourl:https://repository.javeriana.edu.co |
| url |
https://login.ezproxy.javeriana.edu.co/login?url=https://search.ebscohost.com/login.aspx?direct=true&db=edselc&AN=edselc.2-52.0-85064122819&lang=es&site=eds-live http://hdl.handle.net/10554/53316 https://doi.org/10.3233/NPM-1795 |
| identifier_str_mv |
1934-5798 instname:Pontificia Universidad Javeriana reponame:Repositorio Institucional - Pontificia Universidad Javeriana repourl:https://repository.javeriana.edu.co |
| dc.language.iso.spa.fl_str_mv |
eng |
| language |
eng |
| dc.relation.citationstartpage.spa.fl_str_mv |
47 |
| dc.relation.citationendpage.spa.fl_str_mv |
56 |
| dc.relation.ispartofjournal.spa.fl_str_mv |
Journal of Neonatal-Perinatal Medicine |
| dc.relation.citationvolume.spa.fl_str_mv |
12 |
| dc.relation.citationissue.spa.fl_str_mv |
1 |
| dc.rights.licence.*.fl_str_mv |
Atribución-NoComercial 4.0 Internacional |
| dc.rights.uri.*.fl_str_mv |
http://creativecommons.org/licenses/by-nc/4.0/ |
| dc.rights.coar.spa.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 |
| rights_invalid_str_mv |
Atribución-NoComercial 4.0 Internacional http://creativecommons.org/licenses/by-nc/4.0/ http://purl.org/coar/access_right/c_abf2 |
| dc.format.spa.fl_str_mv |
PDF |
| dc.format.mimetype.spa.fl_str_mv |
application/pdf |
| institution |
Pontificia Universidad Javeriana |
| bitstream.url.fl_str_mv |
http://repository.javeriana.edu.co/bitstream/10554/53316/1/Role%20of%20VEGF%20in%20the%20differential%20growth%20between%20the%20fetal%20and%20placental%20ends%20of%20the%20umbilical%20cord.pdf http://repository.javeriana.edu.co/bitstream/10554/53316/2/license.txt http://repository.javeriana.edu.co/bitstream/10554/53316/3/Role%20of%20VEGF%20in%20the%20differential%20growth%20between%20the%20fetal%20and%20placental%20ends%20of%20the%20umbilical%20cord.pdf.jpg |
| bitstream.checksum.fl_str_mv |
62cd699728a7a983401bc9c633b3b1b0 2070d280cc89439d983d9eee1b17df53 20e16128a6215484b5e1f0b7a5e60ad2 |
| bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 |
| repository.name.fl_str_mv |
Repositorio Institucional - Pontificia Universidad Javeriana |
| repository.mail.fl_str_mv |
repositorio@javeriana.edu.co |
| _version_ |
1811671331385638912 |
| spelling |
Atribución-NoComercial 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc/4.0/http://purl.org/coar/access_right/c_abf2Olaya C, MercedesMichael, FG, FabianSilva, J LuisGarzon, A LBernal, J EPontificia Universidad Javeriana. Facultad de Medicina. Departamento de PatologíaResearch Seedbed in Perinatal Medicine Pontificia Universidad Javeriana2021-03-23T15:40:03Z2021-03-23T15:40:03Z2019https://login.ezproxy.javeriana.edu.co/login?url=https://search.ebscohost.com/login.aspx?direct=true&db=edselc&AN=edselc.2-52.0-85064122819&lang=es&site=eds-live1934-5798http://hdl.handle.net/10554/53316https://doi.org/10.3233/NPM-1795instname:Pontificia Universidad Javerianareponame:Repositorio Institucional - Pontificia Universidad Javerianarepourl:https://repository.javeriana.edu.coPDFapplication/pdfengRole of VEGF in the differential growth between the fetal and placental ends of the umbilical cordArtículo de revistahttp://purl.org/coar/resource_type/c_6501Q3Introduction: The umbilical cord (UC) is a vital structure; its alterations affect the newborn and neurological impact can be permanent. Paradoxically, factors that determine it remain unknown. We explore the differential VEGF protein expression in the UC's proximal and distal portions in relation to the hypothesis that the UC has differential growth and that VEGF plays a role in it. Methods: An observational analytical study was performed. One UC segment was taken proximal to fetus and another distal; both were randomly processed; VEGF immunohistochemical analysis was performed; two blinded pathologists read results. Results: Forty-eight newborns were included. Protein expression between the two edges of the umbilical cord, in any kind of cells, was interpreted. Endothelium, amnion, and stromal cells expressed VEGF; the first two were not different between opposite ends. Stromal cells had differential expression: higher in the proximal to the fetus portion. Conclusion: Knowledge of molecular factors is necessary. UC cells widely expressed VEGF, possibly contributing to UC growth. Even though stromal cell expression was different, the interaction with activity close to the fetus must be explored.https://orcid.org/0000-0002-7147-425XN/AUmbilical cordVEGFStillbirthUmbilical cord length4756Journal of Neonatal-Perinatal Medicine121ORIGINALRole of VEGF in the differential growth between the fetal and placental ends of the umbilical cord.pdfRole of VEGF in the differential growth between the fetal and placental ends of the umbilical cord.pdfArtículoapplication/pdf1373384http://repository.javeriana.edu.co/bitstream/10554/53316/1/Role%20of%20VEGF%20in%20the%20differential%20growth%20between%20the%20fetal%20and%20placental%20ends%20of%20the%20umbilical%20cord.pdf62cd699728a7a983401bc9c633b3b1b0MD51embargoed access|||9999-03-20LICENSElicense.txtlicense.txttext/plain; charset=utf-82603http://repository.javeriana.edu.co/bitstream/10554/53316/2/license.txt2070d280cc89439d983d9eee1b17df53MD52open accessTHUMBNAILRole of VEGF in the differential growth between the fetal and placental ends of the umbilical cord.pdf.jpgRole of VEGF in the differential growth between the fetal and placental ends of the umbilical cord.pdf.jpgIM Thumbnailimage/jpeg10866http://repository.javeriana.edu.co/bitstream/10554/53316/3/Role%20of%20VEGF%20in%20the%20differential%20growth%20between%20the%20fetal%20and%20placental%20ends%20of%20the%20umbilical%20cord.pdf.jpg20e16128a6215484b5e1f0b7a5e60ad2MD53open access10554/53316oai:repository.javeriana.edu.co:10554/533162021-07-14 16:29:39.803Repositorio Institucional - Pontificia Universidad Javerianarepositorio@javeriana.edu.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 |