An antioxidant flavonoid has been isolated from methanolic leaf extract of Alchornea coelophylla Pax & K. Hoffm. by means of different column chromatography steps with DIAION HP-20 resin and silica gel in combination with analytical high-performance liquid chromatography (HPLC). It was ident...
- Autores:
-
Martínez, César A; Laboratorio Biotecnología – Productos Naturales, Escuela de Química, Facultad de Tecnologías, Universidad Tecnológica de Pereira, Colombia.
Mosquera, Oscar M; Laboratorio Biotecnología – Productos Naturales, Escuela de Química, Facultad de Tecnologías, Universidad Tecnológica de Pereira, Colombia.
Niño, Jaime; Laboratorio Biotecnología – Productos Naturales, Escuela de Química, Facultad de Tecnologías, Universidad Tecnológica de Pereira, Colombia.
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2016
- Institución:
- Pontificia Universidad Javeriana
- Repositorio:
- Repositorio Universidad Javeriana
- Idioma:
- eng
- OAI Identifier:
- oai:repository.javeriana.edu.co:10554/31748
- Acceso en línea:
- http://revistas.javeriana.edu.co/index.php/scientarium/article/view/17808
http://hdl.handle.net/10554/31748
- Palabra clave:
- null
ABTS•+; Column Chromatography; DPPH•; Euphorbiaceae; NMR; RP-HPLC.
- Rights
- openAccess
- License
- Atribución-NoComercial-SinDerivadas 4.0 Internacional
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Atribución-NoComercial-SinDerivadas 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc/4.0info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Vice-Rectorate for Research, Innovation and Extension, Universidad Tecnológica de Pereira (Funding Code: E9-14-3).Martínez, César A; Laboratorio Biotecnología – Productos Naturales, Escuela de Química, Facultad de Tecnologías, Universidad Tecnológica de Pereira, Colombia.Mosquera, Oscar M; Laboratorio Biotecnología – Productos Naturales, Escuela de Química, Facultad de Tecnologías, Universidad Tecnológica de Pereira, Colombia.Niño, Jaime; Laboratorio Biotecnología – Productos Naturales, Escuela de Química, Facultad de Tecnologías, Universidad Tecnológica de Pereira, Colombia.2018-02-24T16:00:34Z2020-04-15T18:08:20Z2018-02-24T16:00:34Z2020-04-15T18:08:20Z2016-10-04http://revistas.javeriana.edu.co/index.php/scientarium/article/view/1780810.11144/Javeriana.SC21-3.agaa2027-13520122-7483http://hdl.handle.net/10554/31748PDFapplication/pdfengPontificia Universidad Javerianahttp://revistas.javeriana.edu.co/index.php/scientarium/article/view/17808/14025Universitas Scientiarum; Vol 21, No 3 (2016); 245-257Universitas Scientiarum; Vol 21, No 3 (2016); 245-257Universitas Scientiarum; Vol 21, No 3 (2016); 245-257nullABTS•+; Column Chromatography; DPPH•; Euphorbiaceae; NMR; RP-HPLC.nullnullnullhttp://purl.org/coar/version/c_970fb48d4fbd8a85Artículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1info:eu-repo/semantics/articleApigenin glycoside: an antioxidant isolated from Alchornea coelophylla pax & k. Hoffm. (euphorbiaceae) leaf extractAn antioxidant flavonoid has been isolated from methanolic leaf extract of Alchornea coelophylla Pax & K. Hoffm. by means of different column chromatography steps with DIAION HP-20 resin and silica gel in combination with analytical high-performance liquid chromatography (HPLC). It was identified as Apigenin-8-C-(α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside) on the basis of spectroscopic analysis and by comparison with related values reported in the literature. This compound exhibited high in vitro antioxidant activity through DPPH• and ABTS•+ colorimetric assays with IC50 values of 7.528 and 379.7 μg. mL-1, respectively.10554/31748oai:repository.javeriana.edu.co:10554/317482023-03-28 16:15:53.445Repositorio Institucional - Pontificia Universidad Javerianarepositorio@javeriana.edu.co |
dc.title.english.eng.fl_str_mv |
Apigenin glycoside: an antioxidant isolated from Alchornea coelophylla pax & k. Hoffm. (euphorbiaceae) leaf extract |
dc.creator.fl_str_mv |
Martínez, César A; Laboratorio Biotecnología – Productos Naturales, Escuela de Química, Facultad de Tecnologías, Universidad Tecnológica de Pereira, Colombia. Mosquera, Oscar M; Laboratorio Biotecnología – Productos Naturales, Escuela de Química, Facultad de Tecnologías, Universidad Tecnológica de Pereira, Colombia. Niño, Jaime; Laboratorio Biotecnología – Productos Naturales, Escuela de Química, Facultad de Tecnologías, Universidad Tecnológica de Pereira, Colombia. |
dc.contributor.author.none.fl_str_mv |
Martínez, César A; Laboratorio Biotecnología – Productos Naturales, Escuela de Química, Facultad de Tecnologías, Universidad Tecnológica de Pereira, Colombia. Mosquera, Oscar M; Laboratorio Biotecnología – Productos Naturales, Escuela de Química, Facultad de Tecnologías, Universidad Tecnológica de Pereira, Colombia. Niño, Jaime; Laboratorio Biotecnología – Productos Naturales, Escuela de Química, Facultad de Tecnologías, Universidad Tecnológica de Pereira, Colombia. |
dc.contributor.eng.fl_str_mv |
Vice-Rectorate for Research, Innovation and Extension, Universidad Tecnológica de Pereira (Funding Code: E9-14-3). |
dc.subject.eng.fl_str_mv |
null ABTS•+; Column Chromatography; DPPH•; Euphorbiaceae; NMR; RP-HPLC. |
topic |
null ABTS•+; Column Chromatography; DPPH•; Euphorbiaceae; NMR; RP-HPLC. |
spellingShingle |
null ABTS•+; Column Chromatography; DPPH•; Euphorbiaceae; NMR; RP-HPLC. |
description |
An antioxidant flavonoid has been isolated from methanolic leaf extract of Alchornea coelophylla Pax & K. Hoffm. by means of different column chromatography steps with DIAION HP-20 resin and silica gel in combination with analytical high-performance liquid chromatography (HPLC). It was identified as Apigenin-8-C-(α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside) on the basis of spectroscopic analysis and by comparison with related values reported in the literature. This compound exhibited high in vitro antioxidant activity through DPPH• and ABTS•+ colorimetric assays with IC50 values of 7.528 and 379.7 μg. mL-1, respectively. |
publishDate |
2016 |
dc.date.created.none.fl_str_mv |
2016-10-04 |
dc.date.accessioned.none.fl_str_mv |
2018-02-24T16:00:34Z 2020-04-15T18:08:20Z |
dc.date.available.none.fl_str_mv |
2018-02-24T16:00:34Z 2020-04-15T18:08:20Z |
dc.type.coar.fl_str_mv |
http://purl.org/coar/resource_type/c_2df8fbb1 |
dc.type.hasversion.none.fl_str_mv |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
dc.type.local.spa.fl_str_mv |
Artículo de revista |
dc.type.coar.none.fl_str_mv |
http://purl.org/coar/resource_type/c_6501 |
dc.type.driver.none.fl_str_mv |
info:eu-repo/semantics/article |
format |
http://purl.org/coar/resource_type/c_6501 |
dc.identifier.none.fl_str_mv |
http://revistas.javeriana.edu.co/index.php/scientarium/article/view/17808 10.11144/Javeriana.SC21-3.agaa |
dc.identifier.issn.none.fl_str_mv |
2027-1352 0122-7483 |
dc.identifier.uri.none.fl_str_mv |
http://hdl.handle.net/10554/31748 |
url |
http://revistas.javeriana.edu.co/index.php/scientarium/article/view/17808 http://hdl.handle.net/10554/31748 |
identifier_str_mv |
10.11144/Javeriana.SC21-3.agaa 2027-1352 0122-7483 |
dc.language.iso.none.fl_str_mv |
eng |
language |
eng |
dc.relation.uri.none.fl_str_mv |
http://revistas.javeriana.edu.co/index.php/scientarium/article/view/17808/14025 |
dc.relation.citationissue.eng.fl_str_mv |
Universitas Scientiarum; Vol 21, No 3 (2016); 245-257 |
dc.relation.citationissue.spa.fl_str_mv |
Universitas Scientiarum; Vol 21, No 3 (2016); 245-257 |
dc.relation.citationissue.por.fl_str_mv |
Universitas Scientiarum; Vol 21, No 3 (2016); 245-257 |
dc.rights.licence.*.fl_str_mv |
Atribución-NoComercial-SinDerivadas 4.0 Internacional |
dc.rights.uri.eng.fl_str_mv |
http://creativecommons.org/licenses/by-nc/4.0 |
dc.rights.accessrights.none.fl_str_mv |
info:eu-repo/semantics/openAccess |
dc.rights.coar.spa.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 |
rights_invalid_str_mv |
Atribución-NoComercial-SinDerivadas 4.0 Internacional http://creativecommons.org/licenses/by-nc/4.0 http://purl.org/coar/access_right/c_abf2 |
eu_rights_str_mv |
openAccess |
dc.format.spa.fl_str_mv |
PDF |
dc.format.mimetype.spa.fl_str_mv |
application/pdf |
dc.coverage.none.fl_str_mv |
null null null |
dc.publisher.eng.fl_str_mv |
Pontificia Universidad Javeriana |
institution |
Pontificia Universidad Javeriana |
repository.name.fl_str_mv |
Repositorio Institucional - Pontificia Universidad Javeriana |
repository.mail.fl_str_mv |
repositorio@javeriana.edu.co |
_version_ |
1811671236853366784 |