An antioxidant flavonoid has been isolated from methanolic leaf extract of Alchornea coelophylla Pax & K. Hoffm. by means of different column chromatography steps with DIAION HP-20 resin and silica gel in combination with analytical high-performance liquid chromatography (HPLC). It was ident...
- Autores:
-
Martínez, César A; Laboratorio Biotecnología – Productos Naturales, Escuela de Química, Facultad de Tecnologías, Universidad Tecnológica de Pereira, Colombia.
Mosquera, Oscar M; Laboratorio Biotecnología – Productos Naturales, Escuela de Química, Facultad de Tecnologías, Universidad Tecnológica de Pereira, Colombia.
Niño, Jaime; Laboratorio Biotecnología – Productos Naturales, Escuela de Química, Facultad de Tecnologías, Universidad Tecnológica de Pereira, Colombia.
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2016
- Institución:
- Pontificia Universidad Javeriana
- Repositorio:
- Repositorio Universidad Javeriana
- Idioma:
- eng
- OAI Identifier:
- oai:repository.javeriana.edu.co:10554/31748
- Acceso en línea:
- http://revistas.javeriana.edu.co/index.php/scientarium/article/view/17808
http://hdl.handle.net/10554/31748
- Palabra clave:
- null
ABTS•+; Column Chromatography; DPPH•; Euphorbiaceae; NMR; RP-HPLC.
- Rights
- openAccess
- License
- Atribución-NoComercial-SinDerivadas 4.0 Internacional
| Summary: | An antioxidant flavonoid has been isolated from methanolic leaf extract of Alchornea coelophylla Pax & K. Hoffm. by means of different column chromatography steps with DIAION HP-20 resin and silica gel in combination with analytical high-performance liquid chromatography (HPLC). It was identified as Apigenin-8-C-(α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside) on the basis of spectroscopic analysis and by comparison with related values reported in the literature. This compound exhibited high in vitro antioxidant activity through DPPH• and ABTS•+ colorimetric assays with IC50 values of 7.528 and 379.7 μg. mL-1, respectively. |
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