Social and non-social working memory in neurodegeneration
Q1
- Autores:
-
Legaz, Agustina
Prado, Pavel
Moguilner, Sebastian
Baez, Sandra
Santamaria Garcia, Hernando
Birba, Agustina
Barttfeld, Pablo
García, Adolfo M.
Fittipaldi, Sol
Ibañez, Agustín
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2023
- Institución:
- Pontificia Universidad Javeriana
- Repositorio:
- Repositorio Universidad Javeriana
- Idioma:
- eng
- OAI Identifier:
- oai:repository.javeriana.edu.co:10554/65364
- Acceso en línea:
- https://www.sciencedirect.com/science/article/pii/S0969996123001869?via%3Dihub
http://hdl.handle.net/10554/65364
https://doi.org/10.1016/j.nbd.2023.106171
- Palabra clave:
- Working memory
Social processing
Social working memory
Behavioral-variant frontotemporal dementia
Alzheimer’s disease
Parkinson’s disease
- Rights
- License
- Atribución-NoComercial 4.0 Internacional
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| dc.title.spa.fl_str_mv |
Social and non-social working memory in neurodegeneration |
| title |
Social and non-social working memory in neurodegeneration |
| spellingShingle |
Social and non-social working memory in neurodegeneration Working memory Social processing Social working memory Behavioral-variant frontotemporal dementia Alzheimer’s disease Parkinson’s disease |
| title_short |
Social and non-social working memory in neurodegeneration |
| title_full |
Social and non-social working memory in neurodegeneration |
| title_fullStr |
Social and non-social working memory in neurodegeneration |
| title_full_unstemmed |
Social and non-social working memory in neurodegeneration |
| title_sort |
Social and non-social working memory in neurodegeneration |
| dc.creator.fl_str_mv |
Legaz, Agustina Prado, Pavel Moguilner, Sebastian Baez, Sandra Santamaria Garcia, Hernando Birba, Agustina Barttfeld, Pablo García, Adolfo M. Fittipaldi, Sol Ibañez, Agustín |
| dc.contributor.author.none.fl_str_mv |
Legaz, Agustina Prado, Pavel Moguilner, Sebastian Baez, Sandra Santamaria Garcia, Hernando Birba, Agustina Barttfeld, Pablo García, Adolfo M. Fittipaldi, Sol Ibañez, Agustín |
| dc.contributor.corporatename.spa.fl_str_mv |
Pontificia Universidad Javeriana. Facultad de Medicina. Departamento de Psiquiatría y Salud Mental |
| dc.contributor.javerianateacher.none.fl_str_mv |
Santamaria Garcia, Hernando |
| dc.subject.keyword.spa.fl_str_mv |
Working memory Social processing Social working memory Behavioral-variant frontotemporal dementia Alzheimer’s disease Parkinson’s disease |
| topic |
Working memory Social processing Social working memory Behavioral-variant frontotemporal dementia Alzheimer’s disease Parkinson’s disease |
| description |
Q1 |
| publishDate |
2023 |
| dc.date.accessioned.none.fl_str_mv |
2023-08-31T15:00:51Z |
| dc.date.available.none.fl_str_mv |
2023-08-31T15:00:51Z |
| dc.date.created.none.fl_str_mv |
2023-05-29 |
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Artículo de revista |
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http://purl.org/coar/resource_type/c_6501 |
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http://purl.org/coar/resource_type/c_6501 |
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https://www.sciencedirect.com/science/article/pii/S0969996123001869?via%3Dihub |
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0969-9961 / 1095-953X (Electrónico) |
| dc.identifier.uri.none.fl_str_mv |
http://hdl.handle.net/10554/65364 |
| dc.identifier.doi.spa.fl_str_mv |
https://doi.org/10.1016/j.nbd.2023.106171 |
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instname:Pontificia Universidad Javeriana |
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reponame:Repositorio Institucional - Pontificia Universidad Javeriana |
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repourl:https://repository.javeriana.edu.co |
| url |
https://www.sciencedirect.com/science/article/pii/S0969996123001869?via%3Dihub http://hdl.handle.net/10554/65364 https://doi.org/10.1016/j.nbd.2023.106171 |
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0969-9961 / 1095-953X (Electrónico) instname:Pontificia Universidad Javeriana reponame:Repositorio Institucional - Pontificia Universidad Javeriana repourl:https://repository.javeriana.edu.co |
| dc.language.iso.spa.fl_str_mv |
eng |
| language |
eng |
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1 |
| dc.relation.citationendpage.spa.fl_str_mv |
15 |
| dc.relation.ispartofjournal.spa.fl_str_mv |
Neurobiology of Disease |
| dc.relation.citationvolume.spa.fl_str_mv |
183 |
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Atribución-NoComercial 4.0 Internacional |
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http://creativecommons.org/licenses/by-nc/4.0/ |
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Atribución-NoComercial 4.0 Internacional http://creativecommons.org/licenses/by-nc/4.0/ http://purl.org/coar/access_right/c_abf2 |
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PDF |
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Atribución-NoComercial 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc/4.0/http://purl.org/coar/access_right/c_abf2Legaz, AgustinaPrado, PavelMoguilner, SebastianBaez, SandraSantamaria Garcia, HernandoBirba, AgustinaBarttfeld, PabloGarcía, Adolfo M.Fittipaldi, SolIbañez, AgustínPontificia Universidad Javeriana. Facultad de Medicina. Departamento de Psiquiatría y Salud MentalSantamaria Garcia, Hernando2023-08-31T15:00:51Z2023-08-31T15:00:51Z2023-05-29https://www.sciencedirect.com/science/article/pii/S0969996123001869?via%3Dihub0969-9961 / 1095-953X (Electrónico)http://hdl.handle.net/10554/65364https://doi.org/10.1016/j.nbd.2023.106171instname:Pontificia Universidad Javerianareponame:Repositorio Institucional - Pontificia Universidad Javerianarepourl:https://repository.javeriana.edu.coPDFapplication/pdfengSocial and non-social working memory in neurodegenerationArtículo de revistahttp://purl.org/coar/resource_type/c_6501Q1Q1Pacientes con Demencia frontotemporal variante conductualPacientes con enfermedad de AlzheimerPacientes con enfermedad de ParkinsonAlthough social functioning relies on working memory, whether a social-specific mechanism exists remains unclear. This undermines the characterization of neurodegenerative conditions with both working memory and social deficits. We assessed working memory domain-specificity across behavioral, electrophysiological, and neuroimaging dimensions in 245 participants. A novel working memory task involving social and non-social stimuli with three load levels was assessed across controls and different neurodegenerative conditions with recognized impairments in: working memory and social cognition (behavioral-variant frontotemporal dementia); general cognition (Alzheimer’s disease); and unspecific patterns (Parkinson’s disease). We also examined resting-state theta oscillations and functional connectivity correlates of working memory domain-specificity. Results in controls and all groups together evidenced increased working memory demands for social stimuli associated with frontocinguloparietal theta oscillations and salience network connectivity. Canonical frontal theta oscillations and executive-default mode network anticorrelation indexed non-social stimuli. Behavioral-variant frontotemporal dementia presented generalized working memory deficits related to posterior theta oscillations, with social stimuli linked to salience network connectivity. In Alzheimer’s disease, generalized working memory impairments were related to temporoparietal theta oscillations, with non-social stimuli linked to the executive network. Parkinson’s disease showed spared working memory performance and canonical brain correlates. Findings support a social-specific working memory and related disease-selective pathophysiological mechanisms.https://orcid.org/0000-0001-9422-3579Revista Internacional - IndexadaA1NoWorking memorySocial processingSocial working memoryBehavioral-variant frontotemporal dementiaAlzheimer’s diseaseParkinson’s disease115Neurobiology of Disease183LICENSElicense.txtlicense.txttext/plain; charset=utf-82603http://repository.javeriana.edu.co/bitstream/10554/65364/2/license.txt2070d280cc89439d983d9eee1b17df53MD52open accessORIGINALSocial and non-social working memory in neurodegeneration.pdfSocial and non-social working memory in neurodegeneration.pdfArtículoapplication/pdf6572505http://repository.javeriana.edu.co/bitstream/10554/65364/1/Social%20and%20non-social%20working%20memory%20in%20neurodegeneration.pdf70b41e6400538665d6fd4628894d0c7fMD51open accessTHUMBNAILSocial and non-social working memory in neurodegeneration.pdf.jpgSocial and non-social working memory in neurodegeneration.pdf.jpgIM Thumbnailimage/jpeg9749http://repository.javeriana.edu.co/bitstream/10554/65364/3/Social%20and%20non-social%20working%20memory%20in%20neurodegeneration.pdf.jpg002a3bd0afcdb6e02cc248739f7aa3eeMD53open access10554/65364oai:repository.javeriana.edu.co:10554/653642023-09-01 03:04:52.377Repositorio Institucional - Pontificia Universidad Javerianarepositorio@javeriana.edu.coTElDRU5DSUEgWSBBVVRPUklaQUNJw5NOIERFIExPUyBBVVRPUkVTIFBBUkEgUFVCTElDQVIgWSBQRVJNSVRJUiBMQSBDT05TVUxUQSBZIFVTTy4KClBhcnRlIDEuIFTDqXJtaW5vcyBkZSBsYSBsaWNlbmNpYSBnZW5lcmFsIHBhcmEgcHVibGljYWNpw7NuIGRlIG9icmFzIGVuIGVsIHJlcG9zaXRvcmlvIGluc3RpdHVjaW9uYWwKQ29tbyB0aXR1bGFyIChlcykgZGVsIGRlcmVjaG8gZGUgYXV0b3IsIGNvbmZpZXJvIChlcmltb3MpIGEgbGEgUG9udGlmaWNpYSBVbml2ZXJzaWRhZCBKYXZlcmlhbmEgdW5hIGxpY2VuY2lhIG5vIGV4Y2x1c2l2YSwgbGltaXRhZGEgeSBncmF0dWl0YSBzb2JyZSBsYSBvYnJhIHF1ZSBzZSBpbnRlZ3JhcsOhIGVuIGVsIFJlcG9zaXRvcmlvIEluc3RpdHVjaW9uYWwsIHF1ZSBzZSBhanVzdGEgYSBsYXMgc2lndWllbnRlcyBjYXJhY3RlcsOtc3RpY2FzOgphKSAgICAgIEVzdGFyw6EgdmlnZW50ZSBhIHBhcnRpciBkZSBsYSBmZWNoYSBkZSBpbmNsdXNpw7NuIGVuIGVsIHJlcG9zaXRvcmlvLCBwb3IgdW4gcGxhem8gZGUgNSBhw7FvcywgcXVlIHNlcsOhbiBwcm9ycm9nYWJsZXMgaW5kZWZpbmlkYW1lbnRlIHBvciBlbCB0aWVtcG8gcXVlIGR1cmUgZWwgZGVyZWNobyBwYXRyaW1vbmlhbCBkZWwgYXV0b3IuIEVsIGF1dG9yIHBvZHLDoSBkYXIgcG9yIHRlcm1pbmFkYSBsYSBsaWNlbmNpYSBzb2xpY2l0w6FuZG9sbyBhIGxhIFVuaXZlcnNpZGFkIHBvciBlc2NyaXRvLgpiKSAgICAgIEF1dG9yaXphIGEgbGEgUG9udGlmaWNpYSBVbml2ZXJzaWRhZCBKYXZlcmlhbmEgYSBwdWJsaWNhciBsYSBvYnJhIGVuIGRpZ2l0YWwsIGNvbm9jaWVuZG8gcXVlLCBkYWRvIHF1ZSBzZSBwdWJsaWNhIGVuIEludGVybmV0LCBwb3IgZXN0ZSBoZWNobyBjaXJjdWxhIGNvbiB1biBhbGNhbmNlIG11bmRpYWwuCmMpICAgICAgTG9zIGF1dG9yZXMgYWNlcHRhbiBxdWUgbGEgYXV0b3JpemFjacOzbiBzZSBoYWNlIGEgdMOtdHVsbyBncmF0dWl0bywgcG9yIGxvIHRhbnRvIHJlbnVuY2lhbiBhIHJlY2liaXIgYmVuZWZpY2lvIGFsZ3VubyBwb3IgbGEgcHVibGljYWNpw7NuLCBkaXN0cmlidWNpw7NuLCBjb211bmljYWNpw7NuIHDDumJsaWNhIHkgY3VhbHF1aWVyIG90cm8gdXNvIHF1ZSBzZSBoYWdhIGVuIGxvcyB0w6lybWlub3MgZGUgbGEgcHJlc2VudGUgbGljZW5jaWEgeSBkZSBsYSBsaWNlbmNpYSBkZSB1c28gY29uIHF1ZSBzZSBwdWJsaWNhLgpkKSAgICAgIExvcyBhdXRvcmVzIG1hbmlmaWVzdGFuIHF1ZSBzZSB0cmF0YSBkZSB1bmEgb2JyYSBvcmlnaW5hbCBzb2JyZSBsYSBxdWUgdGllbmVuIGxvcyBkZXJlY2hvcyBxdWUgYXV0b3JpemFuIHkgcXVlIHNvbiBlbGxvcyBxdWllbmVzIGFzdW1lbiB0b3RhbCByZXNwb25zYWJpbGlkYWQgcG9yIGVsIGNvbnRlbmlkbyBkZSBzdSBvYnJhIGFudGUgbGEgUG9udGlmaWNpYSBVbml2ZXJzaWRhZCBKYXZlcmlhbmEgeSBhbnRlIHRlcmNlcm9zLiBFbiB0b2RvIGNhc28gbGEgUG9udGlmaWNpYSBVbml2ZXJzaWRhZCBKYXZlcmlhbmEgc2UgY29tcHJvbWV0ZSBhIGluZGljYXIgc2llbXByZSBsYSBhdXRvcsOtYSBpbmNsdXllbmRvIGVsIG5vbWJyZSBkZWwgYXV0b3IgeSBsYSBmZWNoYSBkZSBwdWJsaWNhY2nDs24uCmUpICAgICAgQXV0b3Jpem8gKGFtb3MpIGEgbGEgVW5pdmVyc2lkYWQgcGFyYSBpbmNsdWlyIGxhIG9icmEgZW4gbG9zIMOtbmRpY2VzIHkgYnVzY2Fkb3JlcyBxdWUgZXN0aW1lbiBuZWNlc2FyaW9zIHBhcmEgcHJvbW92ZXIgc3UgZGlmdXNpw7NuLgpmKSAgICAgIEFjZXB0byAoYW1vcykgcXVlIGxhIFBvbnRpZmljaWEgVW5pdmVyc2lkYWQgSmF2ZXJpYW5hIHB1ZWRhIGNvbnZlcnRpciBlbCBkb2N1bWVudG8gYSBjdWFscXVpZXIgbWVkaW8gbyBmb3JtYXRvIHBhcmEgcHJvcMOzc2l0b3MgZGUgcHJlc2VydmFjacOzbiBkaWdpdGFsLgpnKSAgICAgIEF1dG9yaXpvIChhbW9zKSBxdWUgbGEgb2JyYSBzZWEgcHVlc3RhIGEgZGlzcG9zaWNpw7NuIGRlbCBww7pibGljbyBlbiBsb3MgdMOpcm1pbm9zIGF1dG9yaXphZG9zIGVuIGxvcyBsaXRlcmFsZXMgYW50ZXJpb3JlcyBiYWpvIGxvcyBsw61taXRlcyBkZWZpbmlkb3MgcG9yIGxhIHVuaXZlcnNpZGFkIGVuIGxhcyDigJxDb25kaWNpb25lcyBkZSB1c28gZGUgZXN0cmljdG8gY3VtcGxpbWllbnRv4oCdIGRlIGxvcyByZWN1cnNvcyBwdWJsaWNhZG9zIGVuIFJlcG9zaXRvcmlvIEluc3RpdHVjaW9uYWwgUFVKICwgY3V5byB0ZXh0byBjb21wbGV0byBzZSBwdWVkZSBjb25zdWx0YXIgZW4gaHR0cDovL3JlcG9zaXRvcnkuamF2ZXJpYW5hLmVkdS5jby8KClNJIEVMIERPQ1VNRU5UTyBTRSBCQVNBIEVOIFVOIFRSQUJBSk8gUVVFIEhBIFNJRE8gUEFUUk9DSU5BRE8gTyBBUE9ZQURPIFBPUiBVTkEgQUdFTkNJQSBPIFVOQSBPUkdBTklaQUNJw5NOLCBDT04gRVhDRVBDScOTTiBERSBMQSBQT05USUZJQ0lBIFVOSVZFUlNJREFEIEpBVkVSSUFOQSwgRUwgKExPUykgQVVUT1IoRVMpIEdBUkFOVElaQShNT1MpIFFVRSBTRSBIQSBDVU1QTElETyBDT04gTE9TIERFUkVDSE9TIFkgT0JMSUdBQ0lPTkVTIFJFUVVFUklET1MgUE9SIEVMIFJFU1BFQ1RJVk8gQ09OVFJBVE8gTyBBQ1VFUkRPLgo= |