Posterior quadrant epilepsy surgery: case series of a South American hospital

Pacientes con Epilepsia del cuadrante posterior

Autores:
Velasco Marquez, Mario
Cardenas-Cruz, Andres Felipe
Aguilera-Pena, Maria Paula
Vargas-Moreno, Alejandro
Nariño González, Daniel
Pérez Poveda, Juan Carlos
Zorro Guio, Óscar Fernando
Tipo de recurso:
Article of investigation
Fecha de publicación:
2022
Institución:
Pontificia Universidad Javeriana
Repositorio:
Repositorio Universidad Javeriana
Idioma:
eng
OAI Identifier:
oai:repository.javeriana.edu.co:10554/62385
Acceso en línea:
https://aepi.biomedcentral.com/articles/10.1186/s42494-022-00098-w
http://hdl.handle.net/10554/62385
https://doi.org/10.1186/s42494-022-00098-w
Palabra clave:
Posterior cortex
Epilepsy surgery
Posterior quadrant epilepsy
Rights
License
Atribución-NoComercial 4.0 Internacional
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network_name_str Repositorio Universidad Javeriana
repository_id_str
dc.title.spa.fl_str_mv Posterior quadrant epilepsy surgery: case series of a South American hospital
title Posterior quadrant epilepsy surgery: case series of a South American hospital
spellingShingle Posterior quadrant epilepsy surgery: case series of a South American hospital
Posterior cortex
Epilepsy surgery
Posterior quadrant epilepsy
title_short Posterior quadrant epilepsy surgery: case series of a South American hospital
title_full Posterior quadrant epilepsy surgery: case series of a South American hospital
title_fullStr Posterior quadrant epilepsy surgery: case series of a South American hospital
title_full_unstemmed Posterior quadrant epilepsy surgery: case series of a South American hospital
title_sort Posterior quadrant epilepsy surgery: case series of a South American hospital
dc.creator.fl_str_mv Velasco Marquez, Mario
Cardenas-Cruz, Andres Felipe
Aguilera-Pena, Maria Paula
Vargas-Moreno, Alejandro
Nariño González, Daniel
Pérez Poveda, Juan Carlos
Zorro Guio, Óscar Fernando
dc.contributor.author.none.fl_str_mv Velasco Marquez, Mario
Cardenas-Cruz, Andres Felipe
Aguilera-Pena, Maria Paula
Vargas-Moreno, Alejandro
Nariño González, Daniel
Pérez Poveda, Juan Carlos
Zorro Guio, Óscar Fernando
dc.contributor.corporatename.spa.fl_str_mv Pontificia Universidad Javeriana. Facultad de Medicina. Departamento de Neurociencias. Neurología
dc.contributor.javerianateacher.none.fl_str_mv Nariño González, Daniel
dc.subject.keyword.spa.fl_str_mv Posterior cortex
Epilepsy surgery
Posterior quadrant epilepsy
topic Posterior cortex
Epilepsy surgery
Posterior quadrant epilepsy
description Pacientes con Epilepsia del cuadrante posterior
publishDate 2022
dc.date.accessioned.none.fl_str_mv 2022-12-06T12:44:12Z
dc.date.available.none.fl_str_mv 2022-12-06T12:44:12Z
dc.date.created.none.fl_str_mv 2022-10-10
dc.type.local.spa.fl_str_mv Artículo de revista
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format http://purl.org/coar/resource_type/c_2df8fbb1
dc.identifier.spa.fl_str_mv https://aepi.biomedcentral.com/articles/10.1186/s42494-022-00098-w
dc.identifier.issn.spa.fl_str_mv 2096-9384 / 2524-4434 (Electrónico)
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/10554/62385
dc.identifier.doi.spa.fl_str_mv https://doi.org/10.1186/s42494-022-00098-w
dc.identifier.instname.spa.fl_str_mv instname:Pontificia Universidad Javeriana
dc.identifier.reponame.spa.fl_str_mv reponame:Repositorio Institucional - Pontificia Universidad Javeriana
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url https://aepi.biomedcentral.com/articles/10.1186/s42494-022-00098-w
http://hdl.handle.net/10554/62385
https://doi.org/10.1186/s42494-022-00098-w
identifier_str_mv 2096-9384 / 2524-4434 (Electrónico)
instname:Pontificia Universidad Javeriana
reponame:Repositorio Institucional - Pontificia Universidad Javeriana
repourl:https://repository.javeriana.edu.co
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.citationstartpage.spa.fl_str_mv 1
dc.relation.citationendpage.spa.fl_str_mv 6
dc.relation.ispartofjournal.spa.fl_str_mv Acta Epileptologica
dc.relation.citationvolume.spa.fl_str_mv 4
dc.rights.licence.*.fl_str_mv Atribución-NoComercial 4.0 Internacional
dc.rights.uri.*.fl_str_mv http://creativecommons.org/licenses/by-nc/4.0/
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rights_invalid_str_mv Atribución-NoComercial 4.0 Internacional
http://creativecommons.org/licenses/by-nc/4.0/
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dc.format.spa.fl_str_mv PDF
dc.format.mimetype.spa.fl_str_mv application/pdf
dc.coverage.spatial.spa.fl_str_mv América del Sur
Colombia
dc.coverage.temporal.none.fl_str_mv 2006-2019
dc.coverage.city.spa.fl_str_mv Bogotá (Colombia)
institution Pontificia Universidad Javeriana
bitstream.url.fl_str_mv http://repository.javeriana.edu.co/bitstream/10554/62385/1/Posterior%20quadrant%20epilepsy%20surgery%20case%20series%20of%20a%20South%20American%20hospital.pdf
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repository.name.fl_str_mv Repositorio Institucional - Pontificia Universidad Javeriana
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spelling Atribución-NoComercial 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc/4.0/http://purl.org/coar/access_right/c_abf2Velasco Marquez, MarioCardenas-Cruz, Andres FelipeAguilera-Pena, Maria PaulaVargas-Moreno, AlejandroNariño González, DanielPérez Poveda, Juan CarlosZorro Guio, Óscar FernandoPontificia Universidad Javeriana. Facultad de Medicina. Departamento de Neurociencias. NeurologíaNariño González, DanielAmérica del SurColombia2006-2019Bogotá (Colombia)2022-12-06T12:44:12Z2022-12-06T12:44:12Z2022-10-10https://aepi.biomedcentral.com/articles/10.1186/s42494-022-00098-w2096-9384 / 2524-4434 (Electrónico)http://hdl.handle.net/10554/62385https://doi.org/10.1186/s42494-022-00098-winstname:Pontificia Universidad Javerianareponame:Repositorio Institucional - Pontificia Universidad Javerianarepourl:https://repository.javeriana.edu.coPDFapplication/pdfengPosterior quadrant epilepsy surgery: case series of a South American hospitalArtículo de revistahttp://purl.org/coar/resource_type/c_2df8fbb1Pacientes con Epilepsia del cuadrante posteriorBackground: Posterior quadrant epilepsy (PCE) is a type of focal epilepsy that originates in the parietal lobe, occipital lobe, and the parietal-occipital border of the temporal lobe, or in any combination of these regions. PCE has a low incidence, but it can cause a great burden in disability-adjusted life years. In this retrospective cohort, patients of all ages with a diagnosis of PCE between 2006 and 2019 were evaluated in a referral center in Bogotá, Colombia. A descriptive analysis of demographic data, clinical history, imaging findings, type of surgery, histopathological diagnosis, outcome, and follow-up was performed using the Engel scale. Methods: This study included refractory PCE patients of all ages who were evaluated by the epilepsy surgery group of the Hospital Universitario San Ignacio from 2006 to 2019. Clinical, imaging and surgical variables were obtained from the medical records and analyzed. Results: Thirteen patients were included in the study, including 8 males and 5 females. The mean age of diagnosis was 8.8 years, while the mean age of surgery was 25 years. The most frequent clinical finding was intellectual disability. The most common findings on magnetic resonance imaging were encephalomalacia and gliosis. In 61.5% of the patients, the lateralization of video-EEG matched with brain magnetic resonance imaging alteration. The most frequent types of surgery performed were lobectomies, lesionectomies and cortical resections. Seizure-freedom was achieved in approximately one third of the patients; however, more than half of the patients were free of disabling seizures or had significant improvement after surgery. Conclusions: PCE surgery is scarcely performed worldwide, therefore the effectiveness and outcomes are quite variable in the reported literature. In this study, we show that patients with PCE can obtain great benefits in terms of reduction of seizures with a low risk of surgical complications, encouraging the use of this type of procedure in carefully selected patients.https://orcid.org/0000-0001-8829-846Xhttps://orcid.org/0000-0003-4967-4906https://orcid.org/0000-0001-7361-6891https://orcid.org/0000-0003-1044-3043https://orcid.org/0000-0003-3467-222Xhttps://orcid.org/0000-0001-5360-5650https://orcid.org/0000-0002-9362-2487Revista Internacional - No indexadaNoPosterior cortexEpilepsy surgeryPosterior quadrant epilepsy16Acta Epileptologica4ORIGINALPosterior quadrant epilepsy surgery case series of a South American hospital.pdfPosterior quadrant epilepsy surgery case series of a South American hospital.pdfArtículoapplication/pdf679558http://repository.javeriana.edu.co/bitstream/10554/62385/1/Posterior%20quadrant%20epilepsy%20surgery%20case%20series%20of%20a%20South%20American%20hospital.pdf00d7ec79d7db925d5dc699d00eabe5bcMD51open accessLICENSElicense.txtlicense.txttext/plain; charset=utf-82603http://repository.javeriana.edu.co/bitstream/10554/62385/2/license.txt2070d280cc89439d983d9eee1b17df53MD52open accessTHUMBNAILPosterior quadrant epilepsy surgery case series of a South American hospital.pdf.jpgPosterior quadrant epilepsy surgery case series of a South American hospital.pdf.jpgIM Thumbnailimage/jpeg9961http://repository.javeriana.edu.co/bitstream/10554/62385/3/Posterior%20quadrant%20epilepsy%20surgery%20case%20series%20of%20a%20South%20American%20hospital.pdf.jpgdb9f5dffcc678938d2761c904a7fe407MD53open access10554/62385oai:repository.javeriana.edu.co:10554/623852022-12-07 03:01:40.105Repositorio Institucional - Pontificia Universidad Javerianarepositorio@javeriana.edu.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