Tongue muscle mass is associated with total grey matter and hippocampal volumes in Dementia with Lewy Bodies
Q2
- Autores:
-
Borda, Miguel Germán
Castellanos-Perilla, Nicolás
Tovar Rios, Diego Alejandro
Ferreira, Daniel
Duque, Gustavo
Aarsland, Dag
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2022
- Institución:
- Pontificia Universidad Javeriana
- Repositorio:
- Repositorio Universidad Javeriana
- Idioma:
- eng
- OAI Identifier:
- oai:repository.javeriana.edu.co:10554/59016
- Acceso en línea:
- https://www.sciencedirect.com/science/article/pii/S0167494322000280?via%3Dihub
http://hdl.handle.net/10554/59016
https://doi.org/10.1016/j.archger.2022.104647
- Palabra clave:
- Demencia
Grasa intramuscular
Músculo
Demencia con cuerpos de Lewy
Enfermedad de Alzheimer
Sarcopenia
Dementia
Intramuscular fat
Muscle
Dementia with Lewy Bodies
Alzheimer's disease
Sarcopenia
- Rights
- License
- Atribución-NoComercial 4.0 Internacional
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Repositorio Universidad Javeriana |
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| dc.title.spa.fl_str_mv |
Tongue muscle mass is associated with total grey matter and hippocampal volumes in Dementia with Lewy Bodies |
| title |
Tongue muscle mass is associated with total grey matter and hippocampal volumes in Dementia with Lewy Bodies |
| spellingShingle |
Tongue muscle mass is associated with total grey matter and hippocampal volumes in Dementia with Lewy Bodies Demencia Grasa intramuscular Músculo Demencia con cuerpos de Lewy Enfermedad de Alzheimer Sarcopenia Dementia Intramuscular fat Muscle Dementia with Lewy Bodies Alzheimer's disease Sarcopenia |
| title_short |
Tongue muscle mass is associated with total grey matter and hippocampal volumes in Dementia with Lewy Bodies |
| title_full |
Tongue muscle mass is associated with total grey matter and hippocampal volumes in Dementia with Lewy Bodies |
| title_fullStr |
Tongue muscle mass is associated with total grey matter and hippocampal volumes in Dementia with Lewy Bodies |
| title_full_unstemmed |
Tongue muscle mass is associated with total grey matter and hippocampal volumes in Dementia with Lewy Bodies |
| title_sort |
Tongue muscle mass is associated with total grey matter and hippocampal volumes in Dementia with Lewy Bodies |
| dc.creator.fl_str_mv |
Borda, Miguel Germán Castellanos-Perilla, Nicolás Tovar Rios, Diego Alejandro Ferreira, Daniel Duque, Gustavo Aarsland, Dag |
| dc.contributor.author.none.fl_str_mv |
Borda, Miguel Germán Castellanos-Perilla, Nicolás Tovar Rios, Diego Alejandro Ferreira, Daniel Duque, Gustavo Aarsland, Dag |
| dc.contributor.corporatename.spa.fl_str_mv |
Pontificia Universidad Javeriana. Facultad de Medicina. Instituto de Envejecimiento |
| dc.contributor.ascribedclinicalteacher.none.fl_str_mv |
Borda, Miguel Germán |
| dc.contributor.bachelorstudent.none.fl_str_mv |
Castellanos-Perilla, Nicolás |
| dc.subject.spa.fl_str_mv |
Demencia Grasa intramuscular Músculo Demencia con cuerpos de Lewy Enfermedad de Alzheimer Sarcopenia |
| topic |
Demencia Grasa intramuscular Músculo Demencia con cuerpos de Lewy Enfermedad de Alzheimer Sarcopenia Dementia Intramuscular fat Muscle Dementia with Lewy Bodies Alzheimer's disease Sarcopenia |
| dc.subject.keyword.spa.fl_str_mv |
Dementia Intramuscular fat Muscle Dementia with Lewy Bodies Alzheimer's disease Sarcopenia |
| description |
Q2 |
| publishDate |
2022 |
| dc.date.accessioned.none.fl_str_mv |
2022-02-08T17:53:36Z |
| dc.date.available.none.fl_str_mv |
2022-02-08T17:53:36Z |
| dc.date.created.none.fl_str_mv |
2022-02-01 |
| dc.type.local.spa.fl_str_mv |
Artículo de revista |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
| dc.identifier.spa.fl_str_mv |
https://www.sciencedirect.com/science/article/pii/S0167494322000280?via%3Dihub |
| dc.identifier.issn.spa.fl_str_mv |
0167-4943 / 1872-6976 (Electrónico) |
| dc.identifier.uri.none.fl_str_mv |
http://hdl.handle.net/10554/59016 |
| dc.identifier.doi.spa.fl_str_mv |
https://doi.org/10.1016/j.archger.2022.104647 |
| dc.identifier.instname.spa.fl_str_mv |
instname:Pontificia Universidad Javeriana |
| dc.identifier.reponame.spa.fl_str_mv |
reponame:Repositorio Institucional - Pontificia Universidad Javeriana |
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repourl:https://repository.javeriana.edu.co |
| url |
https://www.sciencedirect.com/science/article/pii/S0167494322000280?via%3Dihub http://hdl.handle.net/10554/59016 https://doi.org/10.1016/j.archger.2022.104647 |
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0167-4943 / 1872-6976 (Electrónico) instname:Pontificia Universidad Javeriana reponame:Repositorio Institucional - Pontificia Universidad Javeriana repourl:https://repository.javeriana.edu.co |
| dc.language.iso.spa.fl_str_mv |
eng |
| language |
eng |
| dc.relation.citationstartpage.spa.fl_str_mv |
1 |
| dc.relation.citationendpage.spa.fl_str_mv |
6 |
| dc.relation.ispartofjournal.spa.fl_str_mv |
Archives of Gerontology and Geriatrics |
| dc.relation.citationvolume.spa.fl_str_mv |
100 |
| dc.rights.licence.*.fl_str_mv |
Atribución-NoComercial 4.0 Internacional |
| dc.rights.uri.*.fl_str_mv |
http://creativecommons.org/licenses/by-nc/4.0/ |
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http://purl.org/coar/access_right/c_abf2 |
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Atribución-NoComercial 4.0 Internacional http://creativecommons.org/licenses/by-nc/4.0/ http://purl.org/coar/access_right/c_abf2 |
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PDF |
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application/pdf |
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Noruega |
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Repositorio Institucional - Pontificia Universidad Javeriana |
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Atribución-NoComercial 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc/4.0/http://purl.org/coar/access_right/c_abf2Borda, Miguel GermánCastellanos-Perilla, NicolásTovar Rios, Diego AlejandroFerreira, DanielDuque, GustavoAarsland, DagPontificia Universidad Javeriana. Facultad de Medicina. Instituto de EnvejecimientoBorda, Miguel GermánCastellanos-Perilla, NicolásNoruega2022-02-08T17:53:36Z2022-02-08T17:53:36Z2022-02-01https://www.sciencedirect.com/science/article/pii/S0167494322000280?via%3Dihub0167-4943 / 1872-6976 (Electrónico)http://hdl.handle.net/10554/59016https://doi.org/10.1016/j.archger.2022.104647instname:Pontificia Universidad Javerianareponame:Repositorio Institucional - Pontificia Universidad Javerianarepourl:https://repository.javeriana.edu.coPDFapplication/pdfengDemenciaGrasa intramuscularMúsculoDemencia con cuerpos de LewyEnfermedad de AlzheimerSarcopeniaDementiaIntramuscular fatMuscleDementia with Lewy BodiesAlzheimer's diseaseSarcopeniaTongue muscle mass is associated with total grey matter and hippocampal volumes in Dementia with Lewy BodiesArtículo de revistahttp://purl.org/coar/resource_type/c_2df8fbb1Q2Q1Pacientes con Enfermedad de AlzheimerPacientes con Demencia con cuerpos de LewyBackground: Age-related neurodegeneration, sarcopenia, and ectopic fat accumulation are conditions with shared pathways that remain poorly understood. We have measured muscle volume and fat accumulation in masseter and tongue muscle, and aim to explore their association with the total grey matter volume using MRI in older adults recently diagnosed with Alzheimer's disease (AD) and Dementia with Lewy bodies (DLB). Methods: In this cross-sectional study, people newly diagnosed with mild AD (n=33) and DLB (n=20) underwent structural head MRI. Muscle volume and intramuscular fat (iMAT) of the tongue and masseter were computed using Slice-O-Matic software for segmentation. Total grey volume and hippocampal volumetric segmentation were performed with the FreeSurfer image analysis suite version 6.0. Independent regression models were employed to analyse the associations. Results: Tongue iMAT was higher and total grey volume lower in DLB compared to AD. In the DLB group, tongue muscle was positively associated with total grey matter volume Est 0.92 (SE 0.24 p-value 0.002), left- Est 0.01 (SE 0.0028 p-value 0,002), and right- Est 0.0088 (SE 0.0027 p-value: 0.005) hippocampal volume. There were no statistically significant results for AD. Conclusion: Tongue muscle volume was positively associated with hippocampal and total grey volume in DLB. Longitudinal designs are required to explore the extent and significance of this association.https://orcid.org/0000-0001-5832-0603https://orcid.org/0000-0002-8229-2611https://scholar.google.com/citations?user=MrICwaMAAAAJ&hl=enhttps://scienti.minciencias.gov.co/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0001429659&lang=esRevista Internacional - IndexadaA116Archives of Gerontology and Geriatrics100ORIGINALTongue muscle mass is associated.pdfTongue muscle mass is associated.pdfArtículoapplication/pdf2302905http://repository.javeriana.edu.co/bitstream/10554/59016/1/Tongue%20muscle%20mass%20is%20associated.pdf319ef29d5c3325f2f706e5493211e579MD51open accessLICENSElicense.txtlicense.txttext/plain; charset=utf-82603http://repository.javeriana.edu.co/bitstream/10554/59016/2/license.txt2070d280cc89439d983d9eee1b17df53MD52open accessTHUMBNAILTongue muscle mass is associated.pdf.jpgTongue muscle mass is associated.pdf.jpgIM Thumbnailimage/jpeg10202http://repository.javeriana.edu.co/bitstream/10554/59016/3/Tongue%20muscle%20mass%20is%20associated.pdf.jpg63f29aa71a689d089d15b71102e57a39MD53open access10554/59016oai:repository.javeriana.edu.co:10554/590162023-04-05 11:47:29.218Repositorio Institucional - Pontificia Universidad Javerianarepositorio@javeriana.edu.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 |