Advanced management of ventricular arrhythmias in chronic Chagas cardiomyopathy
Chagas cardiomyopathy is a parasitic infection caused by Trypa-nosoma cruzi. Structural and functional abnormalities are the result of direct myocardial damage by the parasite, immunological reactions, dysautonomia, and microvascular alterations. Chronic Chagas cardiomyopathy (CCC) is the most serio...
- Autores:
-
Santacruz, David
Rosas, Fernando
Hardy, Carina Abigail
Ospina, Diego
Rosas, Andrea Nathalie
Camargo, Juan Manuel
Bermúdez, Juan José
Betancourt, Juan Felipe
Velasco, Víctor Manuel
González, Mario D.
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2021
- Institución:
- Pontificia Universidad Javeriana
- Repositorio:
- Repositorio Universidad Javeriana
- Idioma:
- eng
- OAI Identifier:
- oai:repository.javeriana.edu.co:10554/62268
- Acceso en línea:
- https://www.heartrhythmopen.com/article/S2666-5018(21)00207-5/fulltext#secsectitle0010
http://hdl.handle.net/10554/62268
https://doi.org/10.1016/j.hroo.2021.10.010
- Palabra clave:
- Antiarrhythmic treatment
Cardiomyopathy
Catheter ablation
Chagas disease
Endo-epicardial approach
Implantable cardioverter-defibrillator
Neuraxial modulation
Ventricular tachycardia
- Rights
- License
- Atribución-NoComercial 4.0 Internacional
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Repositorio Universidad Javeriana |
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|
dc.title.spa.fl_str_mv |
Advanced management of ventricular arrhythmias in chronic Chagas cardiomyopathy |
title |
Advanced management of ventricular arrhythmias in chronic Chagas cardiomyopathy |
spellingShingle |
Advanced management of ventricular arrhythmias in chronic Chagas cardiomyopathy Antiarrhythmic treatment Cardiomyopathy Catheter ablation Chagas disease Endo-epicardial approach Implantable cardioverter-defibrillator Neuraxial modulation Ventricular tachycardia |
title_short |
Advanced management of ventricular arrhythmias in chronic Chagas cardiomyopathy |
title_full |
Advanced management of ventricular arrhythmias in chronic Chagas cardiomyopathy |
title_fullStr |
Advanced management of ventricular arrhythmias in chronic Chagas cardiomyopathy |
title_full_unstemmed |
Advanced management of ventricular arrhythmias in chronic Chagas cardiomyopathy |
title_sort |
Advanced management of ventricular arrhythmias in chronic Chagas cardiomyopathy |
dc.creator.fl_str_mv |
Santacruz, David Rosas, Fernando Hardy, Carina Abigail Ospina, Diego Rosas, Andrea Nathalie Camargo, Juan Manuel Bermúdez, Juan José Betancourt, Juan Felipe Velasco, Víctor Manuel González, Mario D. |
dc.contributor.author.none.fl_str_mv |
Santacruz, David Rosas, Fernando Hardy, Carina Abigail Ospina, Diego Rosas, Andrea Nathalie Camargo, Juan Manuel Bermúdez, Juan José Betancourt, Juan Felipe Velasco, Víctor Manuel González, Mario D. |
dc.contributor.corporatename.spa.fl_str_mv |
Pontificia Universidad Javeriana. Facultad de Medicina. Departamento de Medicina Interna. Cardiología |
dc.contributor.javerianateacher.none.fl_str_mv |
Betancourt, Juan Felipe |
dc.subject.keyword.spa.fl_str_mv |
Antiarrhythmic treatment Cardiomyopathy Catheter ablation Chagas disease Endo-epicardial approach Implantable cardioverter-defibrillator Neuraxial modulation Ventricular tachycardia |
topic |
Antiarrhythmic treatment Cardiomyopathy Catheter ablation Chagas disease Endo-epicardial approach Implantable cardioverter-defibrillator Neuraxial modulation Ventricular tachycardia |
description |
Chagas cardiomyopathy is a parasitic infection caused by Trypa-nosoma cruzi. Structural and functional abnormalities are the result of direct myocardial damage by the parasite, immunological reactions, dysautonomia, and microvascular alterations. Chronic Chagas cardiomyopathy (CCC) is the most serious and important manifestation of the disease, affecting up to 30% of patients in the chronic phase. It results in heart failure, arrhythmias, thromboembolism, and sudden cardiac death. As in other cardiomyopathies, scar-related reentry frequently results in ventricular tachycardia (VT). The scars typically are located in the inferior and lateral aspects of the left ventricle close to the mitral annulus extending from endocardium to epicardium. The scars may be more prominent in the epicardium than in the endocardium, so epicardial mapping and ablation frequently are required. Identification of late potentials during sinus rhythm and mid-diastolic potentials during hemodynamically tolerated VT are the main targets for ablation. High-density mapping during sinus rhythm can identify late isochronal regions that are then targeted for ablation. Preablation cardiac magnetic resonance imaging with late enhancement can identify potentials areas of arrhythmogenesis. Therapeutic alternatives for VT management include antiarrhythmic drugs and modulation of the cardiac autonomic nervous system. |
publishDate |
2021 |
dc.date.created.none.fl_str_mv |
2021-12-17 |
dc.date.accessioned.none.fl_str_mv |
2022-11-15T16:44:57Z |
dc.date.available.none.fl_str_mv |
2022-11-15T16:44:57Z |
dc.type.local.spa.fl_str_mv |
Artículo de revista |
dc.type.coar.spa.fl_str_mv |
http://purl.org/coar/resource_type/c_6501 |
format |
http://purl.org/coar/resource_type/c_6501 |
dc.identifier.spa.fl_str_mv |
https://www.heartrhythmopen.com/article/S2666-5018(21)00207-5/fulltext#secsectitle0010 |
dc.identifier.issn.spa.fl_str_mv |
2666-5018 |
dc.identifier.uri.none.fl_str_mv |
http://hdl.handle.net/10554/62268 |
dc.identifier.doi.spa.fl_str_mv |
https://doi.org/10.1016/j.hroo.2021.10.010 |
dc.identifier.instname.spa.fl_str_mv |
instname:Pontificia Universidad Javeriana |
dc.identifier.reponame.spa.fl_str_mv |
reponame:Repositorio Institucional - Pontificia Universidad Javeriana |
dc.identifier.repourl.spa.fl_str_mv |
repourl:https://repository.javeriana.edu.co |
url |
https://www.heartrhythmopen.com/article/S2666-5018(21)00207-5/fulltext#secsectitle0010 http://hdl.handle.net/10554/62268 https://doi.org/10.1016/j.hroo.2021.10.010 |
identifier_str_mv |
2666-5018 instname:Pontificia Universidad Javeriana reponame:Repositorio Institucional - Pontificia Universidad Javeriana repourl:https://repository.javeriana.edu.co |
dc.language.iso.spa.fl_str_mv |
eng |
language |
eng |
dc.relation.citationstartpage.spa.fl_str_mv |
807 |
dc.relation.citationendpage.spa.fl_str_mv |
818 |
dc.relation.ispartofjournal.spa.fl_str_mv |
Heart Rhythm O2 |
dc.relation.citationvolume.spa.fl_str_mv |
2 |
dc.relation.citationissue.spa.fl_str_mv |
6, Parte B |
dc.rights.licence.*.fl_str_mv |
Atribución-NoComercial 4.0 Internacional |
dc.rights.uri.*.fl_str_mv |
http://creativecommons.org/licenses/by-nc/4.0/ |
dc.rights.coar.spa.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 |
rights_invalid_str_mv |
Atribución-NoComercial 4.0 Internacional http://creativecommons.org/licenses/by-nc/4.0/ http://purl.org/coar/access_right/c_abf2 |
dc.format.spa.fl_str_mv |
PDF |
dc.format.mimetype.spa.fl_str_mv |
application/pdf |
institution |
Pontificia Universidad Javeriana |
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repository.name.fl_str_mv |
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Atribución-NoComercial 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc/4.0/http://purl.org/coar/access_right/c_abf2Santacruz, DavidRosas, FernandoHardy, Carina AbigailOspina, DiegoRosas, Andrea NathalieCamargo, Juan ManuelBermúdez, Juan JoséBetancourt, Juan FelipeVelasco, Víctor ManuelGonzález, Mario D.Pontificia Universidad Javeriana. Facultad de Medicina. Departamento de Medicina Interna. CardiologíaBetancourt, Juan Felipe2022-11-15T16:44:57Z2022-11-15T16:44:57Z2021-12-17https://www.heartrhythmopen.com/article/S2666-5018(21)00207-5/fulltext#secsectitle00102666-5018http://hdl.handle.net/10554/62268https://doi.org/10.1016/j.hroo.2021.10.010instname:Pontificia Universidad Javerianareponame:Repositorio Institucional - Pontificia Universidad Javerianarepourl:https://repository.javeriana.edu.coPDFapplication/pdfengAdvanced management of ventricular arrhythmias in chronic Chagas cardiomyopathyArtículo de revistahttp://purl.org/coar/resource_type/c_6501Antiarrhythmic treatmentCardiomyopathyCatheter ablationChagas diseaseEndo-epicardial approachImplantable cardioverter-defibrillatorNeuraxial modulationVentricular tachycardiaChagas cardiomyopathy is a parasitic infection caused by Trypa-nosoma cruzi. Structural and functional abnormalities are the result of direct myocardial damage by the parasite, immunological reactions, dysautonomia, and microvascular alterations. Chronic Chagas cardiomyopathy (CCC) is the most serious and important manifestation of the disease, affecting up to 30% of patients in the chronic phase. It results in heart failure, arrhythmias, thromboembolism, and sudden cardiac death. As in other cardiomyopathies, scar-related reentry frequently results in ventricular tachycardia (VT). The scars typically are located in the inferior and lateral aspects of the left ventricle close to the mitral annulus extending from endocardium to epicardium. The scars may be more prominent in the epicardium than in the endocardium, so epicardial mapping and ablation frequently are required. Identification of late potentials during sinus rhythm and mid-diastolic potentials during hemodynamically tolerated VT are the main targets for ablation. High-density mapping during sinus rhythm can identify late isochronal regions that are then targeted for ablation. Preablation cardiac magnetic resonance imaging with late enhancement can identify potentials areas of arrhythmogenesis. Therapeutic alternatives for VT management include antiarrhythmic drugs and modulation of the cardiac autonomic nervous system.Revista Internacional - No indexadaNo807818Heart Rhythm O226, Parte BORIGINALAdvanced management of ventricular arrhythmias in chronic Chagas cardiomyopathy.pdfAdvanced management of ventricular arrhythmias in chronic Chagas cardiomyopathy.pdfArtículoapplication/pdf2588154http://repository.javeriana.edu.co/bitstream/10554/62268/1/Advanced%20management%20of%20ventricular%20arrhythmias%20in%20chronic%20Chagas%20cardiomyopathy.pdf2c45be37f52f3363b8dbd54cf3eebf85MD51open accessLICENSElicense.txtlicense.txttext/plain; charset=utf-82603http://repository.javeriana.edu.co/bitstream/10554/62268/2/license.txt2070d280cc89439d983d9eee1b17df53MD52open accessTHUMBNAILAdvanced management of ventricular arrhythmias in chronic Chagas cardiomyopathy.pdf.jpgAdvanced management of ventricular arrhythmias in chronic Chagas cardiomyopathy.pdf.jpgIM Thumbnailimage/jpeg14085http://repository.javeriana.edu.co/bitstream/10554/62268/3/Advanced%20management%20of%20ventricular%20arrhythmias%20in%20chronic%20Chagas%20cardiomyopathy.pdf.jpg07d58b6c1b45db2ef100cec12f73ff2bMD53open access10554/62268oai:repository.javeriana.edu.co:10554/622682022-12-08 23:12:25.393Repositorio Institucional - Pontificia Universidad Javerianarepositorio@javeriana.edu.coTElDRU5DSUEgWSBBVVRPUklaQUNJw5NOIERFIExPUyBBVVRPUkVTIFBBUkEgUFVCTElDQVIgWSBQRVJNSVRJUiBMQSBDT05TVUxUQSBZIFVTTy4KClBhcnRlIDEuIFTDqXJtaW5vcyBkZSBsYSBsaWNlbmNpYSBnZW5lcmFsIHBhcmEgcHVibGljYWNpw7NuIGRlIG9icmFzIGVuIGVsIHJlcG9zaXRvcmlvIGluc3RpdHVjaW9uYWwKQ29tbyB0aXR1bGFyIChlcykgZGVsIGRlcmVjaG8gZGUgYXV0b3IsIGNvbmZpZXJvIChlcmltb3MpIGEgbGEgUG9udGlmaWNpYSBVbml2ZXJzaWRhZCBKYXZlcmlhbmEgdW5hIGxpY2VuY2lhIG5vIGV4Y2x1c2l2YSwgbGltaXRhZGEgeSBncmF0dWl0YSBzb2JyZSBsYSBvYnJhIHF1ZSBzZSBpbnRlZ3JhcsOhIGVuIGVsIFJlcG9zaXRvcmlvIEluc3RpdHVjaW9uYWwsIHF1ZSBzZSBhanVzdGEgYSBsYXMgc2lndWllbnRlcyBjYXJhY3RlcsOtc3RpY2FzOgphKSAgICAgIEVzdGFyw6EgdmlnZW50ZSBhIHBhcnRpciBkZSBsYSBmZWNoYSBkZSBpbmNsdXNpw7NuIGVuIGVsIHJlcG9zaXRvcmlvLCBwb3IgdW4gcGxhem8gZGUgNSBhw7FvcywgcXVlIHNlcsOhbiBwcm9ycm9nYWJsZXMgaW5kZWZpbmlkYW1lbnRlIHBvciBlbCB0aWVtcG8gcXVlIGR1cmUgZWwgZGVyZWNobyBwYXRyaW1vbmlhbCBkZWwgYXV0b3IuIEVsIGF1dG9yIHBvZHLDoSBkYXIgcG9yIHRlcm1pbmFkYSBsYSBsaWNlbmNpYSBzb2xpY2l0w6FuZG9sbyBhIGxhIFVuaXZlcnNpZGFkIHBvciBlc2NyaXRvLgpiKSAgICAgIEF1dG9yaXphIGEgbGEgUG9udGlmaWNpYSBVbml2ZXJzaWRhZCBKYXZlcmlhbmEgYSBwdWJsaWNhciBsYSBvYnJhIGVuIGRpZ2l0YWwsIGNvbm9jaWVuZG8gcXVlLCBkYWRvIHF1ZSBzZSBwdWJsaWNhIGVuIEludGVybmV0LCBwb3IgZXN0ZSBoZWNobyBjaXJjdWxhIGNvbiB1biBhbGNhbmNlIG11bmRpYWwuCmMpICAgICAgTG9zIGF1dG9yZXMgYWNlcHRhbiBxdWUgbGEgYXV0b3JpemFjacOzbiBzZSBoYWNlIGEgdMOtdHVsbyBncmF0dWl0bywgcG9yIGxvIHRhbnRvIHJlbnVuY2lhbiBhIHJlY2liaXIgYmVuZWZpY2lvIGFsZ3VubyBwb3IgbGEgcHVibGljYWNpw7NuLCBkaXN0cmlidWNpw7NuLCBjb211bmljYWNpw7NuIHDDumJsaWNhIHkgY3VhbHF1aWVyIG90cm8gdXNvIHF1ZSBzZSBoYWdhIGVuIGxvcyB0w6lybWlub3MgZGUgbGEgcHJlc2VudGUgbGljZW5jaWEgeSBkZSBsYSBsaWNlbmNpYSBkZSB1c28gY29uIHF1ZSBzZSBwdWJsaWNhLgpkKSAgICAgIExvcyBhdXRvcmVzIG1hbmlmaWVzdGFuIHF1ZSBzZSB0cmF0YSBkZSB1bmEgb2JyYSBvcmlnaW5hbCBzb2JyZSBsYSBxdWUgdGllbmVuIGxvcyBkZXJlY2hvcyBxdWUgYXV0b3JpemFuIHkgcXVlIHNvbiBlbGxvcyBxdWllbmVzIGFzdW1lbiB0b3RhbCByZXNwb25zYWJpbGlkYWQgcG9yIGVsIGNvbnRlbmlkbyBkZSBzdSBvYnJhIGFudGUgbGEgUG9udGlmaWNpYSBVbml2ZXJzaWRhZCBKYXZlcmlhbmEgeSBhbnRlIHRlcmNlcm9zLiBFbiB0b2RvIGNhc28gbGEgUG9udGlmaWNpYSBVbml2ZXJzaWRhZCBKYXZlcmlhbmEgc2UgY29tcHJvbWV0ZSBhIGluZGljYXIgc2llbXByZSBsYSBhdXRvcsOtYSBpbmNsdXllbmRvIGVsIG5vbWJyZSBkZWwgYXV0b3IgeSBsYSBmZWNoYSBkZSBwdWJsaWNhY2nDs24uCmUpICAgICAgQXV0b3Jpem8gKGFtb3MpIGEgbGEgVW5pdmVyc2lkYWQgcGFyYSBpbmNsdWlyIGxhIG9icmEgZW4gbG9zIMOtbmRpY2VzIHkgYnVzY2Fkb3JlcyBxdWUgZXN0aW1lbiBuZWNlc2FyaW9zIHBhcmEgcHJvbW92ZXIgc3UgZGlmdXNpw7NuLgpmKSAgICAgIEFjZXB0byAoYW1vcykgcXVlIGxhIFBvbnRpZmljaWEgVW5pdmVyc2lkYWQgSmF2ZXJpYW5hIHB1ZWRhIGNvbnZlcnRpciBlbCBkb2N1bWVudG8gYSBjdWFscXVpZXIgbWVkaW8gbyBmb3JtYXRvIHBhcmEgcHJvcMOzc2l0b3MgZGUgcHJlc2VydmFjacOzbiBkaWdpdGFsLgpnKSAgICAgIEF1dG9yaXpvIChhbW9zKSBxdWUgbGEgb2JyYSBzZWEgcHVlc3RhIGEgZGlzcG9zaWNpw7NuIGRlbCBww7pibGljbyBlbiBsb3MgdMOpcm1pbm9zIGF1dG9yaXphZG9zIGVuIGxvcyBsaXRlcmFsZXMgYW50ZXJpb3JlcyBiYWpvIGxvcyBsw61taXRlcyBkZWZpbmlkb3MgcG9yIGxhIHVuaXZlcnNpZGFkIGVuIGxhcyDigJxDb25kaWNpb25lcyBkZSB1c28gZGUgZXN0cmljdG8gY3VtcGxpbWllbnRv4oCdIGRlIGxvcyByZWN1cnNvcyBwdWJsaWNhZG9zIGVuIFJlcG9zaXRvcmlvIEluc3RpdHVjaW9uYWwgUFVKICwgY3V5byB0ZXh0byBjb21wbGV0byBzZSBwdWVkZSBjb25zdWx0YXIgZW4gaHR0cDovL3JlcG9zaXRvcnkuamF2ZXJpYW5hLmVkdS5jby8KClNJIEVMIERPQ1VNRU5UTyBTRSBCQVNBIEVOIFVOIFRSQUJBSk8gUVVFIEhBIFNJRE8gUEFUUk9DSU5BRE8gTyBBUE9ZQURPIFBPUiBVTkEgQUdFTkNJQSBPIFVOQSBPUkdBTklaQUNJw5NOLCBDT04gRVhDRVBDScOTTiBERSBMQSBQT05USUZJQ0lBIFVOSVZFUlNJREFEIEpBVkVSSUFOQSwgRUwgKExPUykgQVVUT1IoRVMpIEdBUkFOVElaQShNT1MpIFFVRSBTRSBIQSBDVU1QTElETyBDT04gTE9TIERFUkVDSE9TIFkgT0JMSUdBQ0lPTkVTIFJFUVVFUklET1MgUE9SIEVMIFJFU1BFQ1RJVk8gQ09OVFJBVE8gTyBBQ1VFUkRPLgo= |