Dementia in Latin America : paving the way toward a regional action plan

Q1

Autores:
Parra, Mario Alfredo
Báez, Sandra
Sedeño, Lucas
González Campo, Cecilia
Santamaría-García, Hernando
Aprahamian, Ivan
Bertolucci, Paulo HF
Bustin, Julián
Camargos Bicalho, Maria Aparecida
Cano Gutiérrez, Carlos Alberto
Caramelli, Paulo
Chaves, Marcia L. F.
Cogram, Patricia
Costa Beber, Bárbara
Court, Felipe A.
Cruz de Souza, Leonardo
Custodio, Nilton
Damian, Andres
de la Cruz, Myriam
Diehl Rodriguez, Roberta
Dozzi Brucki, Sonia María
Fajersztajn, Lais
Farías, Gonzalo A.
De Felice, Fernanda G.
Ferrari, Raffaele
Ferreira de Oliveira, Fabricio
Ferreira, Sergio T.
Ferretti, Ceres
Figueredo Balthazar, Marcio Luiz
Ferreira Frota, Norberto Anizio
Fuentes, Patricio
García, Adolfo M.
García, Patricia J.
de Gobbi Porto, Fábio Henrique
Duque Peñailillo, Lissette
Willy Engler, Henry
Maier, Irene
Mata, Ignacio F.
Gonzalez-Billault, Christian
López, Oscar L.
Morelli, Laura
Nitrini, Ricardo
Quiroz, Yakeel T.
Guerrero Barragan, Alejandra
Huepe, David
Joao Pio, Fabricio
Kimie Suemoto, Claudia
Kochhann, Renata
Kochen, Silvia
Kumfor, Fiona
Lanata, Serggio
Miller, Bruce
Lessa Mansur, Leticia
Lie Hosogi, Mirna
Lillo, Patricia
Llibre Guerra, Jorge
Lira, David
Lopera, Francisco
Comas, Adelina
Avila-Funes, José Alberto
Sosa, Ana Luisa
Ramos, Claudia
França Resende, Elisa de Paula
Snyder, Heather M.
Tarnanas, Ioannis
Yokoyama, Jenifer
Llibre, Juan
Cardona, Juan Felipe
Possin, Kate
Kosik, Kenneth S.
Montesinos, Rosa
Moguilner, Sebastian
Lourdes Solis, Patricia Cristina
Lucena Ferretti-Rebustini, Renata Eloah de
Martin Ramirez, Jeronimo
Matallana, Diana
Mbakile-Mahlanza, Lingani
Marques Ton, Alyne Mendonça
Melo Tavares, Ronnielly
Miotto, Eliane C.
Muniz-Terrera, Graciela
Muñoz-Nevárez, Luis Arnoldo
Orozco, David
Okada de Oliveira, Maira
Piguet, Olivier
Pintado Caipa, Maritza
Piña Escudero, Stefanie Danielle
Porcello Schilling, Lucas
Rodrigues Palmeira, André Luiz
Sanches Yassuda, Mônica
Santacruz-Escudero, Jose Manuel
Bernardo Serafim, Rodrigo
Smid, Jerusa
Slachevsky, Andrea
Serrano, Cecilia
Soto-Añari, Marcio
Tadao Takada, Leonel
Tenenholz Grinberg, Lea
Lucio Teixeira, Antonio
Tonidandel Barbosa, Maira
Trépel, Dominic
Ibanez, Agustin
Tipo de recurso:
Article of data
Fecha de publicación:
2021
Institución:
Pontificia Universidad Javeriana
Repositorio:
Repositorio Universidad Javeriana
Idioma:
eng
OAI Identifier:
oai:repository.javeriana.edu.co:10554/54853
Acceso en línea:
https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/alz.12202
http://hdl.handle.net/10554/54853
https://doi.org/10.1002/alz.12202
Palabra clave:
Latin America
Biomarkers
Clinical trials
Dementia
Epidemiology
Evidence-based recommendations
Genetics
Knowledge to action framework
Networking and translational research
Nonpharmacological interventions.
Rights
License
Atribución-NoComercial 4.0 Internacional
id JAVERIANA2_1129396f11eedde26170ac42b2bbccad
oai_identifier_str oai:repository.javeriana.edu.co:10554/54853
network_acronym_str JAVERIANA2
network_name_str Repositorio Universidad Javeriana
repository_id_str
dc.title.spa.fl_str_mv Dementia in Latin America : paving the way toward a regional action plan
title Dementia in Latin America : paving the way toward a regional action plan
spellingShingle Dementia in Latin America : paving the way toward a regional action plan
Latin America
Biomarkers
Clinical trials
Dementia
Epidemiology
Evidence-based recommendations
Genetics
Knowledge to action framework
Networking and translational research
Nonpharmacological interventions.
title_short Dementia in Latin America : paving the way toward a regional action plan
title_full Dementia in Latin America : paving the way toward a regional action plan
title_fullStr Dementia in Latin America : paving the way toward a regional action plan
title_full_unstemmed Dementia in Latin America : paving the way toward a regional action plan
title_sort Dementia in Latin America : paving the way toward a regional action plan
dc.creator.fl_str_mv Parra, Mario Alfredo
Báez, Sandra
Sedeño, Lucas
González Campo, Cecilia
Santamaría-García, Hernando
Aprahamian, Ivan
Bertolucci, Paulo HF
Bustin, Julián
Camargos Bicalho, Maria Aparecida
Cano Gutiérrez, Carlos Alberto
Caramelli, Paulo
Chaves, Marcia L. F.
Cogram, Patricia
Costa Beber, Bárbara
Court, Felipe A.
Cruz de Souza, Leonardo
Custodio, Nilton
Damian, Andres
de la Cruz, Myriam
Diehl Rodriguez, Roberta
Dozzi Brucki, Sonia María
Fajersztajn, Lais
Farías, Gonzalo A.
De Felice, Fernanda G.
Ferrari, Raffaele
Ferreira de Oliveira, Fabricio
Ferreira, Sergio T.
Ferretti, Ceres
Figueredo Balthazar, Marcio Luiz
Ferreira Frota, Norberto Anizio
Fuentes, Patricio
García, Adolfo M.
García, Patricia J.
de Gobbi Porto, Fábio Henrique
Duque Peñailillo, Lissette
Willy Engler, Henry
Maier, Irene
Mata, Ignacio F.
Gonzalez-Billault, Christian
López, Oscar L.
Morelli, Laura
Nitrini, Ricardo
Quiroz, Yakeel T.
Guerrero Barragan, Alejandra
Huepe, David
Joao Pio, Fabricio
Kimie Suemoto, Claudia
Kochhann, Renata
Kochen, Silvia
Kumfor, Fiona
Lanata, Serggio
Miller, Bruce
Lessa Mansur, Leticia
Lie Hosogi, Mirna
Lillo, Patricia
Llibre Guerra, Jorge
Lira, David
Lopera, Francisco
Comas, Adelina
Avila-Funes, José Alberto
Sosa, Ana Luisa
Ramos, Claudia
França Resende, Elisa de Paula
Snyder, Heather M.
Tarnanas, Ioannis
Yokoyama, Jenifer
Llibre, Juan
Cardona, Juan Felipe
Possin, Kate
Kosik, Kenneth S.
Montesinos, Rosa
Moguilner, Sebastian
Lourdes Solis, Patricia Cristina
Lucena Ferretti-Rebustini, Renata Eloah de
Martin Ramirez, Jeronimo
Matallana, Diana
Mbakile-Mahlanza, Lingani
Marques Ton, Alyne Mendonça
Melo Tavares, Ronnielly
Miotto, Eliane C.
Muniz-Terrera, Graciela
Muñoz-Nevárez, Luis Arnoldo
Orozco, David
Okada de Oliveira, Maira
Piguet, Olivier
Pintado Caipa, Maritza
Piña Escudero, Stefanie Danielle
Porcello Schilling, Lucas
Rodrigues Palmeira, André Luiz
Sanches Yassuda, Mônica
Santacruz-Escudero, Jose Manuel
Bernardo Serafim, Rodrigo
Smid, Jerusa
Slachevsky, Andrea
Serrano, Cecilia
Soto-Añari, Marcio
Tadao Takada, Leonel
Tenenholz Grinberg, Lea
Lucio Teixeira, Antonio
Tonidandel Barbosa, Maira
Trépel, Dominic
Ibanez, Agustin
dc.contributor.author.none.fl_str_mv Parra, Mario Alfredo
Báez, Sandra
Sedeño, Lucas
González Campo, Cecilia
Santamaría-García, Hernando
Aprahamian, Ivan
Bertolucci, Paulo HF
Bustin, Julián
Camargos Bicalho, Maria Aparecida
Cano Gutiérrez, Carlos Alberto
Caramelli, Paulo
Chaves, Marcia L. F.
Cogram, Patricia
Costa Beber, Bárbara
Court, Felipe A.
Cruz de Souza, Leonardo
Custodio, Nilton
Damian, Andres
de la Cruz, Myriam
Diehl Rodriguez, Roberta
Dozzi Brucki, Sonia María
Fajersztajn, Lais
Farías, Gonzalo A.
De Felice, Fernanda G.
Ferrari, Raffaele
Ferreira de Oliveira, Fabricio
Ferreira, Sergio T.
Ferretti, Ceres
Figueredo Balthazar, Marcio Luiz
Ferreira Frota, Norberto Anizio
Fuentes, Patricio
García, Adolfo M.
García, Patricia J.
de Gobbi Porto, Fábio Henrique
Duque Peñailillo, Lissette
Willy Engler, Henry
Maier, Irene
Mata, Ignacio F.
Gonzalez-Billault, Christian
López, Oscar L.
Morelli, Laura
Nitrini, Ricardo
Quiroz, Yakeel T.
Guerrero Barragan, Alejandra
Huepe, David
Joao Pio, Fabricio
Kimie Suemoto, Claudia
Kochhann, Renata
Kochen, Silvia
Kumfor, Fiona
Lanata, Serggio
Miller, Bruce
Lessa Mansur, Leticia
Lie Hosogi, Mirna
Lillo, Patricia
Llibre Guerra, Jorge
Lira, David
Lopera, Francisco
Comas, Adelina
Avila-Funes, José Alberto
Sosa, Ana Luisa
Ramos, Claudia
França Resende, Elisa de Paula
Snyder, Heather M.
Tarnanas, Ioannis
Yokoyama, Jenifer
Llibre, Juan
Cardona, Juan Felipe
Possin, Kate
Kosik, Kenneth S.
Montesinos, Rosa
Moguilner, Sebastian
Lourdes Solis, Patricia Cristina
Lucena Ferretti-Rebustini, Renata Eloah de
Martin Ramirez, Jeronimo
Matallana, Diana
Mbakile-Mahlanza, Lingani
Marques Ton, Alyne Mendonça
Melo Tavares, Ronnielly
Miotto, Eliane C.
Muniz-Terrera, Graciela
Muñoz-Nevárez, Luis Arnoldo
Orozco, David
Okada de Oliveira, Maira
Piguet, Olivier
Pintado Caipa, Maritza
Piña Escudero, Stefanie Danielle
Porcello Schilling, Lucas
Rodrigues Palmeira, André Luiz
Sanches Yassuda, Mônica
Santacruz-Escudero, Jose Manuel
Bernardo Serafim, Rodrigo
Smid, Jerusa
Slachevsky, Andrea
Serrano, Cecilia
Soto-Añari, Marcio
Tadao Takada, Leonel
Tenenholz Grinberg, Lea
Lucio Teixeira, Antonio
Tonidandel Barbosa, Maira
Trépel, Dominic
Ibanez, Agustin
dc.contributor.corporatename.spa.fl_str_mv Pontificia Universidad Javeriana. Facultad de Medicina. Instituto de Envejecimiento
dc.contributor.corporatename.none.fl_str_mv Pontificia Universidad Javeriana. Facultad de Medicina. Departamento de Psiquiatría y Salud Mental
Pontificia Universidad Javeriana. Facultad de Medicina. Hospital Universitario San Ignacio
dc.subject.keyword.spa.fl_str_mv Latin America
Biomarkers
Clinical trials
Dementia
Epidemiology
Evidence-based recommendations
Genetics
Knowledge to action framework
Networking and translational research
Nonpharmacological interventions.
topic Latin America
Biomarkers
Clinical trials
Dementia
Epidemiology
Evidence-based recommendations
Genetics
Knowledge to action framework
Networking and translational research
Nonpharmacological interventions.
description Q1
publishDate 2021
dc.date.accessioned.none.fl_str_mv 2021-07-14T03:54:34Z
dc.date.available.none.fl_str_mv 2021-07-14T03:54:34Z
dc.date.created.none.fl_str_mv 2021
dc.type.local.spa.fl_str_mv Artículo de revista
dc.type.coar.spa.fl_str_mv http://purl.org/coar/resource_type/c_beb9
format http://purl.org/coar/resource_type/c_beb9
dc.identifier.spa.fl_str_mv https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/alz.12202
dc.identifier.issn.spa.fl_str_mv 1552-5260 / 1552-5279 (Electrónico)
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/10554/54853
dc.identifier.doi.spa.fl_str_mv https://doi.org/10.1002/alz.12202
dc.identifier.instname.spa.fl_str_mv instname:Pontificia Universidad Javeriana
dc.identifier.reponame.spa.fl_str_mv reponame:Repositorio Institucional - Pontificia Universidad Javeriana
dc.identifier.repourl.spa.fl_str_mv repourl:https://repository.javeriana.edu.co
url https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/alz.12202
http://hdl.handle.net/10554/54853
https://doi.org/10.1002/alz.12202
identifier_str_mv 1552-5260 / 1552-5279 (Electrónico)
instname:Pontificia Universidad Javeriana
reponame:Repositorio Institucional - Pontificia Universidad Javeriana
repourl:https://repository.javeriana.edu.co
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.citationstartpage.spa.fl_str_mv 295
dc.relation.citationendpage.spa.fl_str_mv 313
dc.relation.ispartofjournal.spa.fl_str_mv Alzheimer's and Dementia
dc.relation.citationvolume.spa.fl_str_mv 17
dc.relation.citationissue.spa.fl_str_mv 2
dc.rights.licence.*.fl_str_mv Atribución-NoComercial 4.0 Internacional
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spelling Atribución-NoComercial 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc/4.0/http://purl.org/coar/access_right/c_abf2Parra, Mario AlfredoBáez, SandraSedeño, LucasGonzález Campo, CeciliaSantamaría-García, HernandoAprahamian, IvanBertolucci, Paulo HFBustin, JuliánCamargos Bicalho, Maria AparecidaCano Gutiérrez, Carlos AlbertoCaramelli, PauloChaves, Marcia L. F.Cogram, PatriciaCosta Beber, BárbaraCourt, Felipe A.Cruz de Souza, LeonardoCustodio, NiltonDamian, Andresde la Cruz, MyriamDiehl Rodriguez, RobertaDozzi Brucki, Sonia MaríaFajersztajn, LaisFarías, Gonzalo A.De Felice, Fernanda G.Ferrari, RaffaeleFerreira de Oliveira, FabricioFerreira, Sergio T.Ferretti, CeresFigueredo Balthazar, Marcio LuizFerreira Frota, Norberto AnizioFuentes, PatricioGarcía, Adolfo M.García, Patricia J.de Gobbi Porto, Fábio HenriqueDuque Peñailillo, LissetteWilly Engler, HenryMaier, IreneMata, Ignacio F.Gonzalez-Billault, ChristianLópez, Oscar L.Morelli, LauraNitrini, RicardoQuiroz, Yakeel T.Guerrero Barragan, AlejandraHuepe, DavidJoao Pio, FabricioKimie Suemoto, ClaudiaKochhann, RenataKochen, SilviaKumfor, FionaLanata, SerggioMiller, BruceLessa Mansur, LeticiaLie Hosogi, MirnaLillo, PatriciaLlibre Guerra, JorgeLira, DavidLopera, FranciscoComas, AdelinaAvila-Funes, José AlbertoSosa, Ana LuisaRamos, ClaudiaFrança Resende, Elisa de PaulaSnyder, Heather M.Tarnanas, IoannisYokoyama, JeniferLlibre, JuanCardona, Juan FelipePossin, KateKosik, Kenneth S.Montesinos, RosaMoguilner, SebastianLourdes Solis, Patricia CristinaLucena Ferretti-Rebustini, Renata Eloah deMartin Ramirez, JeronimoMatallana, DianaMbakile-Mahlanza, LinganiMarques Ton, Alyne MendonçaMelo Tavares, RonniellyMiotto, Eliane C.Muniz-Terrera, GracielaMuñoz-Nevárez, Luis ArnoldoOrozco, DavidOkada de Oliveira, MairaPiguet, OlivierPintado Caipa, MaritzaPiña Escudero, Stefanie DaniellePorcello Schilling, LucasRodrigues Palmeira, André LuizSanches Yassuda, MônicaSantacruz-Escudero, Jose ManuelBernardo Serafim, RodrigoSmid, JerusaSlachevsky, AndreaSerrano, CeciliaSoto-Añari, MarcioTadao Takada, LeonelTenenholz Grinberg, LeaLucio Teixeira, AntonioTonidandel Barbosa, MairaTrépel, DominicIbanez, AgustinPontificia Universidad Javeriana. Facultad de Medicina. Instituto de EnvejecimientoPontificia Universidad Javeriana. Facultad de Medicina. Departamento de Psiquiatría y Salud MentalPontificia Universidad Javeriana. Facultad de Medicina. Hospital Universitario San Ignacio2021-07-14T03:54:34Z2021-07-14T03:54:34Z2021https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/alz.122021552-5260 / 1552-5279 (Electrónico)http://hdl.handle.net/10554/54853https://doi.org/10.1002/alz.12202instname:Pontificia Universidad Javerianareponame:Repositorio Institucional - Pontificia Universidad Javerianarepourl:https://repository.javeriana.edu.coPDFapplication/pdfengDementia in Latin America : paving the way toward a regional action planArtículo de revistahttp://purl.org/coar/resource_type/c_beb9Q1Q1Across Latin American and Caribbean countries (LACs), the fight against dementia faces pressing challenges, such as heterogeneity, diversity, political instability, and socioeconomic disparities. These can be addressed more effectively in a collaborative setting that fosters open exchange of knowledge. In this work, the Latin American and Caribbean Consortium on Dementia (LAC-CD) proposes an agenda for integration to deliver a Knowledge to Action Framework (KtAF). First, we summarize evidence-based strategies (epidemiology, genetics, biomarkers, clinical trials, nonpharmacological interventions, networking, and translational research) and align them to current global strategies to translate regional knowledge into transformative actions. Then we characterize key sources of complexity (genetic isolates, admixture in populations, environmental factors, and barriers to effective interventions), map them to the above challenges, and provide the basic mosaics of knowledge toward a KtAF. Finally, we describe strategies supporting the knowledge creation stage that underpins the translational impact of KtAF.https://orcid.org/0000-0001-5051-3056https://orcid.org/0000-0001-9422-3579https://orcid.org/0000-0001-5680-7880https://orcid.org/0000-0001-6529-7077N/ALatin AmericaBiomarkersClinical trialsDementiaEpidemiologyEvidence-based recommendationsGeneticsKnowledge to action frameworkNetworking and translational researchNonpharmacological interventions.295313Alzheimer's and Dementia172ORIGINALDementia in latinamerica.pdfDementia in latinamerica.pdfArtículoapplication/pdf1779803http://repository.javeriana.edu.co/bitstream/10554/54853/1/Dementia%20in%20latinamerica.pdfbdf535692008de1d33ad716cd5b0d498MD51embargoed access|||9999-12-31LICENSElicense.txtlicense.txttext/plain; charset=utf-82603http://repository.javeriana.edu.co/bitstream/10554/54853/2/license.txt2070d280cc89439d983d9eee1b17df53MD52open accessTHUMBNAILDementia in latinamerica.pdf.jpgDementia in latinamerica.pdf.jpgIM Thumbnailimage/jpeg12119http://repository.javeriana.edu.co/bitstream/10554/54853/3/Dementia%20in%20latinamerica.pdf.jpg8792ed74688bbc8992c019be87ace0c9MD53open access10554/54853oai:repository.javeriana.edu.co:10554/548532022-10-21 09:44:35.124Repositorio Institucional - Pontificia Universidad Javerianarepositorio@javeriana.edu.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