Patients with relapsing polychondritis and previous cartilage trauma present more autoimmunity phenomena

Relapsing polychondritis (RP) is an autoimmune disease characterized by inflammation and destruction of all type of body cartilage, and the cartilage trauma may be a trigger of the disease in a susceptible person. We describe the clinical and laboratory findings in a group of 18 patients with RP wit...

Full description

Autores:
Cañas Dávila, Carlos Alberto
Iglesias Gamarra, Antonio
Toro, Carlos Enrique
Quintana Duque, Mario Andrés
Echeverri, Andrés Felipe
Gómez, Arley R.
Tipo de recurso:
Article of investigation
Fecha de publicación:
2012
Institución:
Universidad ICESI
Repositorio:
Repositorio ICESI
Idioma:
eng
OAI Identifier:
oai:repository.icesi.edu.co:10906/78523
Acceso en línea:
http://www.scopus.com/inward/record.url?eid=2-s2.0-84857062656&partnerID=tZOtx3y1
http://hdl.handle.net/10906/78523
http://dx.doi.org/10.1007/s00296-010-1686-9
Palabra clave:
Ciencias socio biomédicas
Biomedical sciences
Autoimmunity
Trauma
Autoinmunidad
Policondritis recidivante
Relapsing polychondritis
Rights
openAccess
License
https://creativecommons.org/licenses/by-nc-nd/4.0/
Description
Summary:Relapsing polychondritis (RP) is an autoimmune disease characterized by inflammation and destruction of all type of body cartilage, and the cartilage trauma may be a trigger of the disease in a susceptible person. We describe the clinical and laboratory findings in a group of 18 patients with RP with (7 cases) or without (11 cases) anteceding cartilage trauma. The mean age was 41 years in the group with cartilage trauma and 55 years in the group without cartilage trauma. For both groups, female gender was predominant. All patients presented with auricular chondritis. Systemic manifestations and autoimmunity were more common in patients with anteceding trauma. © 2011 Springer-Verlag.