Microcirculatory alterations are associated with pulmonary dead-space fraction in moderate and severe ards

Shunt-induced hypoxemia i s considered the primary pathophysiological abnormality and main diagnostic cri- teria of acute respiratory distress syndrome (ARDS). However, increases in dead- space ventilation (VD/VT) can also contribute to gas exchange alterations in ARDS. Systemic microcirculatory alt...

Full description

Autores:
Ospina Tascón, Gustavo Adolfo
De Backer, D
Salas, CE
Hernández, G
Bruhn, A
Bermúdez, WF
Valencia, JD
Madriñán, HJ
Bautista-Rincón, DF
Tipo de recurso:
Article of investigation
Fecha de publicación:
2015
Institución:
Universidad ICESI
Repositorio:
Repositorio ICESI
Idioma:
eng
OAI Identifier:
oai:repository.icesi.edu.co:10906/82221
Acceso en línea:
http://icm-experimental.springeropen.com/articles/10.1186/2197-425X-3-S1-A453
http://hdl.handle.net/10906/82221
https://doi.org/10.1186/2197-425X-3-S1-A453
Palabra clave:
Ciencias socio biomédicas
Hipoxemia
Sistema respiratorio - Fisiopatologia
Enfermedades pulmonares
Enfermedades respiratorias
Medical sciences
Rights
openAccess
License
https://creativecommons.org/licenses/by-nc-nd/4.0/
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network_acronym_str ICESI2
network_name_str Repositorio ICESI
repository_id_str
spelling Ospina Tascón, Gustavo AdolfoDe Backer, DSalas, CEHernández, GBruhn, ABermúdez, WFValencia, JDMadriñán, HJBautista-Rincón, DFgusospin@gmail.comBerlin de Lat: 52 30 00 N degrees minutes Lat: 52.5000 decimal degrees Long: 013 25 00 E degrees minutes Long: 13.4167 decimal degrees2017-11-03T14:54:46Z2017-11-03T14:54:46Z2015-10-032197-425Xhttp://icm-experimental.springeropen.com/articles/10.1186/2197-425X-3-S1-A453http://hdl.handle.net/10906/82221https://doi.org/10.1186/2197-425X-3-S1-A453instname: Universidad Icesireponame: Biblioteca Digitalrepourl: https://repository.icesi.edu.co/Shunt-induced hypoxemia i s considered the primary pathophysiological abnormality and main diagnostic cri- teria of acute respiratory distress syndrome (ARDS). However, increases in dead- space ventilation (VD/VT) can also contribute to gas exchange alterations in ARDS. Systemic microcirculatory alterations described during inflammatory conditions are characterized by perfusion heterogeneity and theoretically pulmonary microcirculatory heterogene ity could lead to imbalance pulmonary ventilation/perfusion relationship. Thus, we hypothesized that systemic microvascular alterations could reflect increased VD/VT in ARDS.1 páginaDigitalapplication/pdfengSpringer International PublishingFacultad Ciencias de la SaludMedicinaDepartamento de Ciencias Básicas MédicasBerlinIntensive Care Medicine Experimental, Vol. 3, No. Suppl 1 - 2015EL AUTOR, expresa que la obra objeto de la presente autorización es original y la elaboró sin quebrantar ni suplantar los derechos de autor de terceros, y de tal forma, la obra es de su exclusiva autoría y tiene la titularidad sobre éste. PARÁGRAFO: en caso de queja o acción por parte de un tercero referente a los derechos de autor sobre el artículo, folleto o libro en cuestión, EL AUTOR, asumirá la responsabilidad total, y saldrá en defensa de los derechos aquí autorizados; para todos los efectos, la Universidad Icesi actúa como un tercero de buena fe. Esta autorización, permite a la Universidad Icesi, de forma indefinida, para que en los términos establecidos en la Ley 23 de 1982, la Ley 44 de 1993, leyes y jurisprudencia vigente al respecto, haga publicación de este con fines educativos. Toda persona que consulte ya sea la biblioteca o en medio electrónico podrá copiar apartes del texto citando siempre la fuentes, es decir el título del trabajo y el autor.https://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessAtribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)http://purl.org/coar/access_right/c_abf2Ciencias socio biomédicasHipoxemiaSistema respiratorio - FisiopatologiaEnfermedades pulmonaresEnfermedades respiratoriasMedical sciencesMicrocirculatory alterations are associated with pulmonary dead-space fraction in moderate and severe ardsinfo:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_2df8fbb1Artículoinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85Comunidad Universidad Icesi – Investigadores3Suppl 1A453A453TEXTospina_microcirculatory_alterations_2015.pdf.txtospina_microcirculatory_alterations_2015.pdf.txttext/plain5671http://repository.icesi.edu.co/biblioteca_digital/bitstream/10906/82221/2/ospina_microcirculatory_alterations_2015.pdf.txt6bfed3671f486033beeda913a29b76fcMD52ORIGINALospina_microcirculatory_alterations_2015.pdfospina_microcirculatory_alterations_2015.pdfapplication/pdf304172http://repository.icesi.edu.co/biblioteca_digital/bitstream/10906/82221/1/ospina_microcirculatory_alterations_2015.pdf24df8b0dff63a75c79a09cd6eb8fd285MD5110906/82221oai:repository.icesi.edu.co:10906/822212017-11-08 04:31:46.854Biblioteca Digital - Universidad icesicdcriollo@icesi.edu.co
dc.title.none.fl_str_mv Microcirculatory alterations are associated with pulmonary dead-space fraction in moderate and severe ards
title Microcirculatory alterations are associated with pulmonary dead-space fraction in moderate and severe ards
spellingShingle Microcirculatory alterations are associated with pulmonary dead-space fraction in moderate and severe ards
Ciencias socio biomédicas
Hipoxemia
Sistema respiratorio - Fisiopatologia
Enfermedades pulmonares
Enfermedades respiratorias
Medical sciences
title_short Microcirculatory alterations are associated with pulmonary dead-space fraction in moderate and severe ards
title_full Microcirculatory alterations are associated with pulmonary dead-space fraction in moderate and severe ards
title_fullStr Microcirculatory alterations are associated with pulmonary dead-space fraction in moderate and severe ards
title_full_unstemmed Microcirculatory alterations are associated with pulmonary dead-space fraction in moderate and severe ards
title_sort Microcirculatory alterations are associated with pulmonary dead-space fraction in moderate and severe ards
dc.creator.fl_str_mv Ospina Tascón, Gustavo Adolfo
De Backer, D
Salas, CE
Hernández, G
Bruhn, A
Bermúdez, WF
Valencia, JD
Madriñán, HJ
Bautista-Rincón, DF
dc.contributor.author.spa.fl_str_mv Ospina Tascón, Gustavo Adolfo
De Backer, D
Salas, CE
Hernández, G
Bruhn, A
Bermúdez, WF
Valencia, JD
Madriñán, HJ
Bautista-Rincón, DF
dc.subject.spa.fl_str_mv Ciencias socio biomédicas
Hipoxemia
Sistema respiratorio - Fisiopatologia
Enfermedades pulmonares
Enfermedades respiratorias
topic Ciencias socio biomédicas
Hipoxemia
Sistema respiratorio - Fisiopatologia
Enfermedades pulmonares
Enfermedades respiratorias
Medical sciences
dc.subject.eng.fl_str_mv Medical sciences
description Shunt-induced hypoxemia i s considered the primary pathophysiological abnormality and main diagnostic cri- teria of acute respiratory distress syndrome (ARDS). However, increases in dead- space ventilation (VD/VT) can also contribute to gas exchange alterations in ARDS. Systemic microcirculatory alterations described during inflammatory conditions are characterized by perfusion heterogeneity and theoretically pulmonary microcirculatory heterogene ity could lead to imbalance pulmonary ventilation/perfusion relationship. Thus, we hypothesized that systemic microvascular alterations could reflect increased VD/VT in ARDS.
publishDate 2015
dc.date.issued.none.fl_str_mv 2015-10-03
dc.date.accessioned.none.fl_str_mv 2017-11-03T14:54:46Z
dc.date.available.none.fl_str_mv 2017-11-03T14:54:46Z
dc.type.eng.fl_str_mv info:eu-repo/semantics/article
dc.type.coar.none.fl_str_mv http://purl.org/coar/resource_type/c_2df8fbb1
dc.type.local.spa.fl_str_mv Artículo
dc.type.version.eng.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.coarversion.none.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
format http://purl.org/coar/resource_type/c_2df8fbb1
status_str publishedVersion
dc.identifier.issn.none.fl_str_mv 2197-425X
dc.identifier.other.none.fl_str_mv http://icm-experimental.springeropen.com/articles/10.1186/2197-425X-3-S1-A453
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/10906/82221
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1186/2197-425X-3-S1-A453
dc.identifier.instname.none.fl_str_mv instname: Universidad Icesi
dc.identifier.reponame.none.fl_str_mv reponame: Biblioteca Digital
dc.identifier.repourl.none.fl_str_mv repourl: https://repository.icesi.edu.co/
identifier_str_mv 2197-425X
instname: Universidad Icesi
reponame: Biblioteca Digital
repourl: https://repository.icesi.edu.co/
url http://icm-experimental.springeropen.com/articles/10.1186/2197-425X-3-S1-A453
http://hdl.handle.net/10906/82221
https://doi.org/10.1186/2197-425X-3-S1-A453
dc.language.iso.eng.fl_str_mv eng
language eng
dc.relation.ispartof.eng.fl_str_mv Intensive Care Medicine Experimental, Vol. 3, No. Suppl 1 - 2015
dc.rights.uri.none.fl_str_mv https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.accessrights.eng.fl_str_mv info:eu-repo/semantics/openAccess
dc.rights.license.none.fl_str_mv Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)
dc.rights.coar.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/4.0/
Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.extent.none.fl_str_mv 1 página
dc.format.medium.spa.fl_str_mv Digital
dc.format.mimetype.eng.fl_str_mv application/pdf
dc.coverage.spatial.none.fl_str_mv Berlin de Lat: 52 30 00 N degrees minutes Lat: 52.5000 decimal degrees Long: 013 25 00 E degrees minutes Long: 13.4167 decimal degrees
dc.publisher.none.fl_str_mv Springer International Publishing
dc.publisher.faculty.spa.fl_str_mv Facultad Ciencias de la Salud
dc.publisher.program.spa.fl_str_mv Medicina
dc.publisher.department.spa.fl_str_mv Departamento de Ciencias Básicas Médicas
dc.publisher.place.none.fl_str_mv Berlin
publisher.none.fl_str_mv Springer International Publishing
institution Universidad ICESI
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http://repository.icesi.edu.co/biblioteca_digital/bitstream/10906/82221/1/ospina_microcirculatory_alterations_2015.pdf
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repository.name.fl_str_mv Biblioteca Digital - Universidad icesi
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