Is primary hyperparathyroidism a pathogenic factor in some conditions mediated by B lymphocytes hyperactivity?
Several clinical cases have shown the association of primary hyperparathyroidism and immune conditions related to B-cell hyperactivity. In some of these cases the treatment of hyperparathyroidism led to the resolution of the autoimmune phenomena. Thus, this paper hypothesizes that high levels of par...
- Autores:
-
Cañas Dávila, Carlos Alberto
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2013
- Institución:
- Universidad ICESI
- Repositorio:
- Repositorio ICESI
- Idioma:
- eng
- OAI Identifier:
- oai:repository.icesi.edu.co:10906/81224
- Acceso en línea:
- http://www.ncbi.nlm.nih.gov/pubmed/23643707
http://linkinghub.elsevier.com/retrieve/pii/S0306987713001680
http://hdl.handle.net/10906/81224
http://dx.doi.org/10.1016/j.mehy.2013.03.044
- Palabra clave:
- Hiperparatiroidismo
Ciencias socio biomédicas
Medical sciences
Hormona paratiroidea
- Rights
- openAccess
- License
- https://creativecommons.org/licenses/by-nc-nd/4.0/
| Summary: | Several clinical cases have shown the association of primary hyperparathyroidism and immune conditions related to B-cell hyperactivity. In some of these cases the treatment of hyperparathyroidism led to the resolution of the autoimmune phenomena. Thus, this paper hypothesizes that high levels of parathyroid hormone (PTH) may modify B lymphocytes function and induce the development of autoimmunity mediated by B-cell hyperactivity. |
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