Costimulation blockade in pig artery patch xenotransplantation - a simple model to monitor the adaptive immune response in nonhuman primates.

BACKGROUND: CD154 blockade-based immunosuppression successfully prevents both humoral and cellular adaptive immune responses in baboons receiving α1,3-galactosyltransferase gene-knockout (GTKO) pig organs. Using a GTKO pig artery transplantation model in baboons, we evaluated the efficacy of CD28/B7...

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Autores:: Echeverri Junca, Gabriel Jaime

Tipo de recurso:: Article of investigation

Fecha de publicación:: 2012

Institución:: Universidad ICESI

Repositorio:: Repositorio ICESI

Idioma:: eng

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spelling	Echeverri Junca, Gabriel Jaimecooperdk@upmc.eduNew Jersey de Lat: 40 00 00 N degrees minutes Lat: 40.0000 decimal degrees Long: 075 00 00 W degrees minutes Long: -75.0000 decimal degrees2015-10-14T21:57:24Z2015-10-14T21:57:24Z2012-07-010908-665Xhttp://apps.webofknowledge.com/full_record.do?page=1&qid=1&log_event=yes&viewType=fullRecord&SID=4BDShD6T2KTBoAZU7Ey&product=UA&doc=1&search_mode=GeneralSearchhttp://hdl.handle.net/10906/78507http://dx.doi.org/10.1111/j.1399-3089.2012.00711.xinstname: Universidad Icesireponame: Biblioteca Digitalrepourl: https://repository.icesi.edu.co/BACKGROUND: CD154 blockade-based immunosuppression successfully prevents both humoral and cellular adaptive immune responses in baboons receiving α1,3-galactosyltransferase gene-knockout (GTKO) pig organs. Using a GTKO pig artery transplantation model in baboons, we evaluated the efficacy of CD28/B7 costimulatory pathway blockade in comparison with CD154 blockade.11 páginasDigitalapplication/pdfengWileyFacultad Ciencias de la SaludMedicinaDepartamento de Ciencias Básicas MédicasNew JerseyXenotransplantation, Vol. 19, No.4 - 2012EL AUTOR, expresa que la obra objeto de la presente autorización es original y la elaboró sin quebrantar ni suplantar los derechos de autor de terceros, y de tal forma, la obra es de su exclusiva autoría y tiene la titularidad sobre éste. PARÁGRAFO: en caso de queja o acción por parte de un tercero referente a los derechos de autor sobre el artículo, folleto o libro en cuestión, EL AUTOR, asumirá la responsabilidad total, y saldrá en defensa de los derechos aquí autorizados; para todos los efectos, la Universidad Icesi actúa como un tercero de buena fe. Esta autorización, permite a la Universidad Icesi, de forma indefinida, para que en los términos establecidos en la Ley 23 de 1982, la Ley 44 de 1993, leyes y jurisprudencia vigente al respecto, haga publicación de este con fines educativos. Toda persona que consulte ya sea la biblioteca o en medio electrónico podrá copiar apartes del texto citando siempre la fuentes, es decir el título del trabajo y el autor.https://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessAtribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)http://purl.org/coar/access_right/c_abf2Ciencias socio biomédicasAnticuerposTrasplanteArteriaXenotrasplantesMedical sciencesCostimulation blockade in pig artery patch xenotransplantation - a simple model to monitor the adaptive immune response in nonhuman primates.info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_2df8fbb1Artículoinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85Comunidad Universidad Icesi – Investigadores194221232ORIGINALecheverri_costimulation_blockade_2012.pdfecheverri_costimulation_blockade_2012.pdfapplication/pdf5314240http://repository.icesi.edu.co/biblioteca_digital/bitstream/10906/78507/1/echeverri_costimulation_blockade_2012.pdf088c1a140a1595f4d96d94bc782861aeMD5110906/78507oai:repository.icesi.edu.co:10906/785072018-10-25 16:39:42.801Biblioteca Digital - Universidad icesicdcriollo@icesi.edu.co
dc.title.spa.fl_str_mv	Costimulation blockade in pig artery patch xenotransplantation - a simple model to monitor the adaptive immune response in nonhuman primates.
title	Costimulation blockade in pig artery patch xenotransplantation - a simple model to monitor the adaptive immune response in nonhuman primates.
spellingShingle	Costimulation blockade in pig artery patch xenotransplantation - a simple model to monitor the adaptive immune response in nonhuman primates. Ciencias socio biomédicas Anticuerpos Trasplante Arteria Xenotrasplantes Medical sciences
title_short	Costimulation blockade in pig artery patch xenotransplantation - a simple model to monitor the adaptive immune response in nonhuman primates.
title_full	Costimulation blockade in pig artery patch xenotransplantation - a simple model to monitor the adaptive immune response in nonhuman primates.
title_fullStr	Costimulation blockade in pig artery patch xenotransplantation - a simple model to monitor the adaptive immune response in nonhuman primates.
title_full_unstemmed	Costimulation blockade in pig artery patch xenotransplantation - a simple model to monitor the adaptive immune response in nonhuman primates.
title_sort	Costimulation blockade in pig artery patch xenotransplantation - a simple model to monitor the adaptive immune response in nonhuman primates.
dc.creator.fl_str_mv	Echeverri Junca, Gabriel Jaime
dc.contributor.author.spa.fl_str_mv	Echeverri Junca, Gabriel Jaime
dc.subject.none.fl_str_mv	Ciencias socio biomédicas Anticuerpos Trasplante Arteria Xenotrasplantes
topic	Ciencias socio biomédicas Anticuerpos Trasplante Arteria Xenotrasplantes Medical sciences
dc.subject.eng.fl_str_mv	Medical sciences
description	BACKGROUND: CD154 blockade-based immunosuppression successfully prevents both humoral and cellular adaptive immune responses in baboons receiving α1,3-galactosyltransferase gene-knockout (GTKO) pig organs. Using a GTKO pig artery transplantation model in baboons, we evaluated the efficacy of CD28/B7 costimulatory pathway blockade in comparison with CD154 blockade.
publishDate	2012
dc.date.issued.none.fl_str_mv	2012-07-01
dc.date.accessioned.none.fl_str_mv	2015-10-14T21:57:24Z
dc.date.available.none.fl_str_mv	2015-10-14T21:57:24Z
dc.type.eng.fl_str_mv	info:eu-repo/semantics/article
dc.type.coar.none.fl_str_mv	http://purl.org/coar/resource_type/c_2df8fbb1
dc.type.local.spa.fl_str_mv	Artículo
dc.type.version.none.fl_str_mv	info:eu-repo/semantics/publishedVersion
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dc.identifier.issn.none.fl_str_mv	0908-665X
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dc.identifier.uri.none.fl_str_mv	http://hdl.handle.net/10906/78507
dc.identifier.doi.none.fl_str_mv	http://dx.doi.org/10.1111/j.1399-3089.2012.00711.x
dc.identifier.instname.none.fl_str_mv	instname: Universidad Icesi
dc.identifier.reponame.none.fl_str_mv	reponame: Biblioteca Digital
dc.identifier.repourl.none.fl_str_mv	repourl: https://repository.icesi.edu.co/
identifier_str_mv	0908-665X instname: Universidad Icesi reponame: Biblioteca Digital repourl: https://repository.icesi.edu.co/
url	http://apps.webofknowledge.com/full_record.do?page=1&qid=1&log_event=yes&viewType=fullRecord&SID=4BDShD6T2KTBoAZU7Ey&product=UA&doc=1&search_mode=GeneralSearch http://hdl.handle.net/10906/78507 http://dx.doi.org/10.1111/j.1399-3089.2012.00711.x
dc.language.iso.eng.fl_str_mv	eng
language	eng
dc.relation.ispartof.none.fl_str_mv	Xenotransplantation, Vol. 19, No.4 - 2012
dc.rights.uri.none.fl_str_mv	https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.accessrights.spa.fl_str_mv	info:eu-repo/semantics/openAccess
dc.rights.license.none.fl_str_mv	Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)
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eu_rights_str_mv	openAccess
dc.format.extent.spa.fl_str_mv	11 páginas
dc.format.medium.none.fl_str_mv	Digital
dc.format.mimetype.none.fl_str_mv	application/pdf
dc.coverage.spatial.none.fl_str_mv	New Jersey de Lat: 40 00 00 N degrees minutes Lat: 40.0000 decimal degrees Long: 075 00 00 W degrees minutes Long: -75.0000 decimal degrees
dc.publisher.none.fl_str_mv	Wiley
dc.publisher.faculty.spa.fl_str_mv	Facultad Ciencias de la Salud
dc.publisher.program.none.fl_str_mv	Medicina
dc.publisher.department.none.fl_str_mv	Departamento de Ciencias Básicas Médicas
dc.publisher.place.none.fl_str_mv	New Jersey
publisher.none.fl_str_mv	Wiley
institution	Universidad ICESI
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Costimulation blockade in pig artery patch xenotransplantation - a simple model to monitor the adaptive immune response in nonhuman primates.

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