Severe deformans tophaceous gouty arthritis

A 61-year-old man with a 20-year history of gout with severe functional disability was evaluated in our service. He received alopurinol and colchicine without response. Physical examination revealed bilateral great deformity, multiple tophi and edema of hands (Fig. 1), feet and knees. Serum uric aci...

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Autores:
Cañas Dávila, Carlos Alberto
Vernaza Pizarro, Armando
Bonilla Abadía, Fabio
Tobón García, Gabriel Jaime
Zuñiga Velásquez, Alicia
Suso, Juan Pablo
Tipo de recurso:
Article of investigation
Fecha de publicación:
2017
Institución:
Universidad ICESI
Repositorio:
Repositorio ICESI
Idioma:
eng
OAI Identifier:
oai:repository.icesi.edu.co:10906/81411
Acceso en línea:
https://nebulosa.icesi.edu.co:2615/record/display.uri?eid=2-s2.0-84969645972&origin=resultslist&sort=plf-f&src=s&st1=Severe+deformans+tophaceous+gouty+arthritis&st2=Severe+deformans+tophaceous+gouty+arthritis&sid=E01D21DDECC54497C1F7194D30930AB0.wsnAw8kcdt7IPYLO0V48gA%3a670&sot=b&sdt=b&sl=123&s=%28TITLE-ABS-KEY%28Severe+deformans+tophaceous+gouty+arthritis%29+AND+TITLE-ABS-KEY%28Severe+deformans+tophaceous+gouty+arthritis%29%29&relpos=0&citeCnt=0&searchTerm=#
http://hdl.handle.net/10906/81411
http://dx.doi.org/10.1016/j.jbspin.2016.02.025
Palabra clave:
Ciencias socio biomédicas
Medical sciences
Discapacidad
Artritis de gota
Artritis degenerativa
Dermatología
Rights
openAccess
License
https://creativecommons.org/licenses/by-nc-nd/4.0/
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dc.title.spa.fl_str_mv Severe deformans tophaceous gouty arthritis
title Severe deformans tophaceous gouty arthritis
spellingShingle Severe deformans tophaceous gouty arthritis
Ciencias socio biomédicas
Medical sciences
Discapacidad
Artritis de gota
Artritis degenerativa
Dermatología
title_short Severe deformans tophaceous gouty arthritis
title_full Severe deformans tophaceous gouty arthritis
title_fullStr Severe deformans tophaceous gouty arthritis
title_full_unstemmed Severe deformans tophaceous gouty arthritis
title_sort Severe deformans tophaceous gouty arthritis
dc.creator.fl_str_mv Cañas Dávila, Carlos Alberto
Vernaza Pizarro, Armando
Bonilla Abadía, Fabio
Tobón García, Gabriel Jaime
Zuñiga Velásquez, Alicia
Suso, Juan Pablo
dc.contributor.author.spa.fl_str_mv Cañas Dávila, Carlos Alberto
Vernaza Pizarro, Armando
Bonilla Abadía, Fabio
Tobón García, Gabriel Jaime
Zuñiga Velásquez, Alicia
Suso, Juan Pablo
dc.subject.spa.fl_str_mv Ciencias socio biomédicas
Medical sciences
Discapacidad
Artritis de gota
Artritis degenerativa
Dermatología
topic Ciencias socio biomédicas
Medical sciences
Discapacidad
Artritis de gota
Artritis degenerativa
Dermatología
description A 61-year-old man with a 20-year history of gout with severe functional disability was evaluated in our service. He received alopurinol and colchicine without response. Physical examination revealed bilateral great deformity, multiple tophi and edema of hands (Fig. 1), feet and knees. Serum uric acid was elevated: 11.2 mg/dL (reference value: 3.4–7.0 mg/dL). Hands X-ray AP view demonstrated, in both hands (Fig. 2A [left] and B [right]), conserved bone mineralization with severe soft-tissue swelling, extensive erosions with sclerotic borders (white arrows), precipitation of calcium with urate crystals giving density to the tophi (head arrows), bone spiculations (black arrows) and osteolytic expansive lesions in multiple heads of metacarpophalangic joint (double-head arrows).
publishDate 2017
dc.date.accessioned.none.fl_str_mv 2017-05-08T18:48:33Z
dc.date.available.none.fl_str_mv 2017-05-08T18:48:33Z
dc.date.issued.none.fl_str_mv 2017-03-01
dc.type.spa.fl_str_mv info:eu-repo/semantics/article
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http://hdl.handle.net/10906/81411
http://dx.doi.org/10.1016/j.jbspin.2016.02.025
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.ispartof.none.fl_str_mv Joint Bone Spine, Vol. 84, No. 2, - 2017
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dc.publisher.spa.fl_str_mv Elsevier
dc.publisher.faculty.spa.fl_str_mv Facultad de Ciencias de la Salud
dc.publisher.program.spa.fl_str_mv Ciencias de la Salud
dc.publisher.department.spa.fl_str_mv Departamento de Ciencias Básicas Médicas
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dc.publisher.place.none.fl_str_mv Ámsterdam
institution Universidad ICESI
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spelling Cañas Dávila, Carlos AlbertoVernaza Pizarro, ArmandoBonilla Abadía, FabioTobón García, Gabriel JaimeZuñiga Velásquez, AliciaSuso, Juan PabloAmsterdam de Lat: 45 45 00 N degrees minutes Lat: 45.7500 decimal degrees Long: 111 19 00 W degrees minutes Long: -111.3167 decimal degreesAmsterdam de Lat: 37 25 00 N degrees minutes Lat: 37.4167 decimal degrees Long: 120 32 00 W degrees minutes Long: -120.5333 decimal degrees2017-05-08T18:48:33Z2017-05-08T18:48:33Z2017-03-011297-319Xhttps://nebulosa.icesi.edu.co:2615/record/display.uri?eid=2-s2.0-84969645972&origin=resultslist&sort=plf-f&src=s&st1=Severe+deformans+tophaceous+gouty+arthritis&st2=Severe+deformans+tophaceous+gouty+arthritis&sid=E01D21DDECC54497C1F7194D30930AB0.wsnAw8kcdt7IPYLO0V48gA%3a670&sot=b&sdt=b&sl=123&s=%28TITLE-ABS-KEY%28Severe+deformans+tophaceous+gouty+arthritis%29+AND+TITLE-ABS-KEY%28Severe+deformans+tophaceous+gouty+arthritis%29%29&relpos=0&citeCnt=0&searchTerm=#http://hdl.handle.net/10906/81411http://dx.doi.org/10.1016/j.jbspin.2016.02.025instname: Universidad Icesireponame: Biblioteca Digitalrepourl: https://repository.icesi.edu.co/A 61-year-old man with a 20-year history of gout with severe functional disability was evaluated in our service. He received alopurinol and colchicine without response. Physical examination revealed bilateral great deformity, multiple tophi and edema of hands (Fig. 1), feet and knees. Serum uric acid was elevated: 11.2 mg/dL (reference value: 3.4–7.0 mg/dL). Hands X-ray AP view demonstrated, in both hands (Fig. 2A [left] and B [right]), conserved bone mineralization with severe soft-tissue swelling, extensive erosions with sclerotic borders (white arrows), precipitation of calcium with urate crystals giving density to the tophi (head arrows), bone spiculations (black arrows) and osteolytic expansive lesions in multiple heads of metacarpophalangic joint (double-head arrows).1 páginasDigitalengElsevierFacultad de Ciencias de la SaludCiencias de la SaludDepartamento de Ciencias Básicas MédicasAmsterdamÁmsterdamJoint Bone Spine, Vol. 84, No. 2, - 2017EL AUTOR, expresa que la obra objeto de la presente autorización es original y la elaboró sin quebrantar ni suplantar los derechos de autor de terceros, y de tal forma, la obra es de su exclusiva autoría y tiene la titularidad sobre éste. PARÁGRAFO: en caso de queja o acción por parte de un tercero referente a los derechos de autor sobre el artículo, folleto o libro en cuestión, EL AUTOR, asumirá la responsabilidad total, y saldrá en defensa de los derechos aquí autorizados; para todos los efectos, la Universidad Icesi actúa como un tercero de buena fe. Esta autorización, permite a la Universidad Icesi, de forma indefinida, para que en los términos establecidos en la Ley 23 de 1982, la Ley 44 de 1993, leyes y jurisprudencia vigente al respecto, haga publicación de este con fines educativos Todo persona que consulte ya sea la biblioteca o en medio electrónico podrá copiar apartes del texto citando siempre la fuentes, es decir el título del trabajo y el autor.https://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessAtribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)http://purl.org/coar/access_right/c_abf2Ciencias socio biomédicasMedical sciencesDiscapacidadArtritis de gotaArtritis degenerativaDermatologíaSevere deformans tophaceous gouty arthritisinfo:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_2df8fbb1Artículoinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85Comunidad Universidad Icesi - Investigadores842227227ORIGINALdocumento.htmldocumento.htmltext/html309http://repository.icesi.edu.co/biblioteca_digital/bitstream/10906/81411/6/documento.htmla7cd750413260f3c0aec187db65be86cMD56LICENSElicense.txtlicense.txttext/plain1783http://repository.icesi.edu.co/biblioteca_digital/bitstream/10906/81411/5/license.txta9bf6c9d51cc761c4b473f39f5bcb2eaMD55CC-LICENSElicense_urllicense_urltext/plain49http://repository.icesi.edu.co/biblioteca_digital/bitstream/10906/81411/2/license_url4afdbb8c545fd630ea7db775da747b2fMD52license_textlicense_textapplication/octet-stream0http://repository.icesi.edu.co/biblioteca_digital/bitstream/10906/81411/3/license_textd41d8cd98f00b204e9800998ecf8427eMD53license_rdflicense_rdfapplication/octet-stream0http://repository.icesi.edu.co/biblioteca_digital/bitstream/10906/81411/4/license_rdfd41d8cd98f00b204e9800998ecf8427eMD5410906/81411oai:repository.icesi.edu.co:10906/814112018-11-29 14:09:16.291Biblioteca Digital - Universidad icesicdcriollo@icesi.edu.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