Collagenous Colitis-like Condition in Immunosuppressed Infant Baboons

Collagenous colitis is a chronic inflammatory bowel disease of unknown etiology. It is fairly common in adult humans, but rare in infants, and has been associated with autoimmune disorders. METHODS We report four infant baboons (age 7-12 months) that had received a transplant at 3 months of age and...

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Autores:
Montoya, Claudia L.
Wágner, Róbert A.
Wolf, Roman F.
Klein, Edwin C.
Rigatti, Lora H.
Dons, Eefje M.
Echeverri Junca, Gabriel Jaime
Cooper, David KC C.
Ijzermans, Jan Nicolaas Maria
Tipo de recurso:
Article of investigation
Fecha de publicación:
2012
Institución:
Universidad ICESI
Repositorio:
Repositorio ICESI
Idioma:
eng
OAI Identifier:
oai:repository.icesi.edu.co:10906/81191
Acceso en línea:
http://eds.a.ebscohost.com/eds/detail/detail?vid=1&sid=6f8503bc-d924-466a-b500-2aa885ed1a00%40sessionmgr4009&hid=4103&bdata=Jmxhbmc9ZXMmc2l0ZT1lZHMtbGl2ZSZzY29wZT1zaXRl#AN=edselc.2-52.0-84862236367&db=edselc
http://www.pubmedcentral.nih.gov/articlerender.
http://hdl.handle.net/10906/81191
http://dx.doi.org/10.1002/ibd.21900
Palabra clave:
Ciencias socio biomédicas
Medical sciences
Colitis colagenosa
Trasplante
Enfermedades intestinales inflamatorias
Rights
openAccess
License
https://creativecommons.org/licenses/by-nc-nd/4.0/
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oai_identifier_str oai:repository.icesi.edu.co:10906/81191
network_acronym_str ICESI2
network_name_str Repositorio ICESI
repository_id_str
spelling Montoya, Claudia L.Wágner, Róbert A.Wolf, Roman F.Klein, Edwin C.Rigatti, Lora H.Dons, Eefje M.Echeverri Junca, Gabriel JaimeCooper, David KC C.Ijzermans, Jan Nicolaas MariaNew Jersey de Coordinates: Lat: 40 00 00 N degrees minutes Lat: 40.0000 decimal degrees Long: 075 00 00 W degrees minutes Long: -75.0000 decimal degrees2017-03-30T22:41:53Z2017-03-30T22:41:53Z2012-07-011536-4844http://eds.a.ebscohost.com/eds/detail/detail?vid=1&sid=6f8503bc-d924-466a-b500-2aa885ed1a00%40sessionmgr4009&hid=4103&bdata=Jmxhbmc9ZXMmc2l0ZT1lZHMtbGl2ZSZzY29wZT1zaXRl#AN=edselc.2-52.0-84862236367&db=edselchttp://www.pubmedcentral.nih.gov/articlerender.http://hdl.handle.net/10906/81191http://dx.doi.org/10.1002/ibd.21900instname: Universidad Icesireponame: Biblioteca Digitalrepourl: https://repository.icesi.edu.co/Collagenous colitis is a chronic inflammatory bowel disease of unknown etiology. It is fairly common in adult humans, but rare in infants, and has been associated with autoimmune disorders. METHODS We report four infant baboons (age 7-12 months) that had received a transplant at 3 months of age and subsequent immunosuppressive therapy for periods of 4-10 months. All presented identical symptoms within a period of 4 weeks, including weight loss associated with chronic watery diarrhea that was unresponsive to standard antimicrobial treatment. RESULTS Clinical chemistry evaluations were within normal ranges, viral causes were ruled out, and fecal and blood cultures were repeatedly negative. At necropsy, two infant baboons were found to have a form of collagenous colitis. In the remaining two baboons that had identical clinical features, immunosuppressive therapy was discontinued and treatment with budesonide was initiated. Both baboons recovered and remained well on no medication until the end of follow-up (24 months).7 páginasDigitalapplication/pdfengWileyFacultad Ciencias de la SaludMedicinaDepartamento de Ciencias Básicas MédicasNew JerseyInflammatory Bowel Diseases, Vol. 18,No. 7 - 2012EL AUTOR, expresa que la obra objeto de la presente autorización es original y la elaboró sin quebrantar ni suplantar los derechos de autor de terceros, y de tal forma, la obra es de su exclusiva autoría y tiene la titularidad sobre éste. PARÁGRAFO: en caso de queja o acción por parte de un tercero referente a los derechos de autor sobre el artículo, folleto o libro en cuestión, EL AUTOR, asumirá la responsabilidad total, y saldrá en defensa de los derechos aquí autorizados; para todos los efectos, la Universidad Icesi actúa como un tercero de buena fe. Esta autorización, permite a la Universidad Icesi, de forma indefinida, para que en los términos establecidos en la Ley 23 de 1982, la Ley 44 de 1993, leyes y jurisprudencia vigente al respecto, haga publicación de este con fines educativos. Toda persona que consulte ya sea la biblioteca o en medio electrónico podrá copiar apartes del texto citando siempre la fuentes, es decir el título del trabajo y el autor.https://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessAtribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)http://purl.org/coar/access_right/c_abf2Ciencias socio biomédicasMedical sciencesColitis colagenosaTrasplanteEnfermedades intestinales inflamatoriasCollagenous Colitis-like Condition in Immunosuppressed Infant Baboonsinfo:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_2df8fbb1Artículoinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85Comunidad Universidad Icesi – Investigadores13251332ORIGINALecheverri_collagenous_colitis_2012.pdfecheverri_collagenous_colitis_2012.pdfapplication/pdf650356http://repository.icesi.edu.co/biblioteca_digital/bitstream/10906/81191/1/echeverri_collagenous_colitis_2012.pdf789121c7abfc97b6b28c637c4b24d69cMD5110906/81191oai:repository.icesi.edu.co:10906/811912018-10-08 14:04:34.162Biblioteca Digital - Universidad icesicdcriollo@icesi.edu.co
dc.title.spa.fl_str_mv Collagenous Colitis-like Condition in Immunosuppressed Infant Baboons
title Collagenous Colitis-like Condition in Immunosuppressed Infant Baboons
spellingShingle Collagenous Colitis-like Condition in Immunosuppressed Infant Baboons
Ciencias socio biomédicas
Medical sciences
Colitis colagenosa
Trasplante
Enfermedades intestinales inflamatorias
title_short Collagenous Colitis-like Condition in Immunosuppressed Infant Baboons
title_full Collagenous Colitis-like Condition in Immunosuppressed Infant Baboons
title_fullStr Collagenous Colitis-like Condition in Immunosuppressed Infant Baboons
title_full_unstemmed Collagenous Colitis-like Condition in Immunosuppressed Infant Baboons
title_sort Collagenous Colitis-like Condition in Immunosuppressed Infant Baboons
dc.creator.fl_str_mv Montoya, Claudia L.
Wágner, Róbert A.
Wolf, Roman F.
Klein, Edwin C.
Rigatti, Lora H.
Dons, Eefje M.
Echeverri Junca, Gabriel Jaime
Cooper, David KC C.
Ijzermans, Jan Nicolaas Maria
dc.contributor.author.spa.fl_str_mv Montoya, Claudia L.
Wágner, Róbert A.
Wolf, Roman F.
Klein, Edwin C.
Rigatti, Lora H.
Dons, Eefje M.
Echeverri Junca, Gabriel Jaime
Cooper, David KC C.
Ijzermans, Jan Nicolaas Maria
dc.subject.spa.fl_str_mv Ciencias socio biomédicas
topic Ciencias socio biomédicas
Medical sciences
Colitis colagenosa
Trasplante
Enfermedades intestinales inflamatorias
dc.subject.none.fl_str_mv Medical sciences
Colitis colagenosa
Trasplante
Enfermedades intestinales inflamatorias
description Collagenous colitis is a chronic inflammatory bowel disease of unknown etiology. It is fairly common in adult humans, but rare in infants, and has been associated with autoimmune disorders. METHODS We report four infant baboons (age 7-12 months) that had received a transplant at 3 months of age and subsequent immunosuppressive therapy for periods of 4-10 months. All presented identical symptoms within a period of 4 weeks, including weight loss associated with chronic watery diarrhea that was unresponsive to standard antimicrobial treatment. RESULTS Clinical chemistry evaluations were within normal ranges, viral causes were ruled out, and fecal and blood cultures were repeatedly negative. At necropsy, two infant baboons were found to have a form of collagenous colitis. In the remaining two baboons that had identical clinical features, immunosuppressive therapy was discontinued and treatment with budesonide was initiated. Both baboons recovered and remained well on no medication until the end of follow-up (24 months).
publishDate 2012
dc.date.issued.none.fl_str_mv 2012-07-01
dc.date.accessioned.none.fl_str_mv 2017-03-30T22:41:53Z
dc.date.available.none.fl_str_mv 2017-03-30T22:41:53Z
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dc.type.local.none.fl_str_mv Artículo
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http://www.pubmedcentral.nih.gov/articlerender.
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/10906/81191
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dc.identifier.instname.none.fl_str_mv instname: Universidad Icesi
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identifier_str_mv 1536-4844
instname: Universidad Icesi
reponame: Biblioteca Digital
repourl: https://repository.icesi.edu.co/
url http://eds.a.ebscohost.com/eds/detail/detail?vid=1&sid=6f8503bc-d924-466a-b500-2aa885ed1a00%40sessionmgr4009&hid=4103&bdata=Jmxhbmc9ZXMmc2l0ZT1lZHMtbGl2ZSZzY29wZT1zaXRl#AN=edselc.2-52.0-84862236367&db=edselc
http://www.pubmedcentral.nih.gov/articlerender.
http://hdl.handle.net/10906/81191
http://dx.doi.org/10.1002/ibd.21900
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.ispartof.none.fl_str_mv Inflammatory Bowel Diseases, Vol. 18,No. 7 - 2012
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dc.rights.accessrights.none.fl_str_mv info:eu-repo/semantics/openAccess
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rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/4.0/
Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.extent.none.fl_str_mv 7 páginas
dc.format.medium.spa.fl_str_mv Digital
dc.format.mimetype.none.fl_str_mv application/pdf
dc.coverage.spatial.none.fl_str_mv New Jersey de Coordinates: Lat: 40 00 00 N degrees minutes Lat: 40.0000 decimal degrees Long: 075 00 00 W degrees minutes Long: -75.0000 decimal degrees
dc.publisher.none.fl_str_mv Wiley
dc.publisher.faculty.none.fl_str_mv Facultad Ciencias de la Salud
dc.publisher.program.none.fl_str_mv Medicina
dc.publisher.department.none.fl_str_mv Departamento de Ciencias Básicas Médicas
dc.publisher.place.none.fl_str_mv New Jersey
publisher.none.fl_str_mv Wiley
institution Universidad ICESI
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