Collagenous Colitis-like Condition in Immunosuppressed Infant Baboons
Collagenous colitis is a chronic inflammatory bowel disease of unknown etiology. It is fairly common in adult humans, but rare in infants, and has been associated with autoimmune disorders. METHODS We report four infant baboons (age 7-12 months) that had received a transplant at 3 months of age and...
- Autores:
-
Montoya, Claudia L.
Wágner, Róbert A.
Wolf, Roman F.
Klein, Edwin C.
Rigatti, Lora H.
Dons, Eefje M.
Echeverri Junca, Gabriel Jaime
Cooper, David KC C.
Ijzermans, Jan Nicolaas Maria
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2012
- Institución:
- Universidad ICESI
- Repositorio:
- Repositorio ICESI
- Idioma:
- eng
- OAI Identifier:
- oai:repository.icesi.edu.co:10906/81191
- Acceso en línea:
- http://eds.a.ebscohost.com/eds/detail/detail?vid=1&sid=6f8503bc-d924-466a-b500-2aa885ed1a00%40sessionmgr4009&hid=4103&bdata=Jmxhbmc9ZXMmc2l0ZT1lZHMtbGl2ZSZzY29wZT1zaXRl#AN=edselc.2-52.0-84862236367&db=edselc
http://www.pubmedcentral.nih.gov/articlerender.
http://hdl.handle.net/10906/81191
http://dx.doi.org/10.1002/ibd.21900
- Palabra clave:
- Ciencias socio biomédicas
Medical sciences
Colitis colagenosa
Trasplante
Enfermedades intestinales inflamatorias
- Rights
- openAccess
- License
- https://creativecommons.org/licenses/by-nc-nd/4.0/
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Montoya, Claudia L.Wágner, Róbert A.Wolf, Roman F.Klein, Edwin C.Rigatti, Lora H.Dons, Eefje M.Echeverri Junca, Gabriel JaimeCooper, David KC C.Ijzermans, Jan Nicolaas MariaNew Jersey de Coordinates: Lat: 40 00 00 N degrees minutes Lat: 40.0000 decimal degrees Long: 075 00 00 W degrees minutes Long: -75.0000 decimal degrees2017-03-30T22:41:53Z2017-03-30T22:41:53Z2012-07-011536-4844http://eds.a.ebscohost.com/eds/detail/detail?vid=1&sid=6f8503bc-d924-466a-b500-2aa885ed1a00%40sessionmgr4009&hid=4103&bdata=Jmxhbmc9ZXMmc2l0ZT1lZHMtbGl2ZSZzY29wZT1zaXRl#AN=edselc.2-52.0-84862236367&db=edselchttp://www.pubmedcentral.nih.gov/articlerender.http://hdl.handle.net/10906/81191http://dx.doi.org/10.1002/ibd.21900instname: Universidad Icesireponame: Biblioteca Digitalrepourl: https://repository.icesi.edu.co/Collagenous colitis is a chronic inflammatory bowel disease of unknown etiology. It is fairly common in adult humans, but rare in infants, and has been associated with autoimmune disorders. METHODS We report four infant baboons (age 7-12 months) that had received a transplant at 3 months of age and subsequent immunosuppressive therapy for periods of 4-10 months. All presented identical symptoms within a period of 4 weeks, including weight loss associated with chronic watery diarrhea that was unresponsive to standard antimicrobial treatment. RESULTS Clinical chemistry evaluations were within normal ranges, viral causes were ruled out, and fecal and blood cultures were repeatedly negative. At necropsy, two infant baboons were found to have a form of collagenous colitis. In the remaining two baboons that had identical clinical features, immunosuppressive therapy was discontinued and treatment with budesonide was initiated. Both baboons recovered and remained well on no medication until the end of follow-up (24 months).7 páginasDigitalapplication/pdfengWileyFacultad Ciencias de la SaludMedicinaDepartamento de Ciencias Básicas MédicasNew JerseyInflammatory Bowel Diseases, Vol. 18,No. 7 - 2012EL AUTOR, expresa que la obra objeto de la presente autorización es original y la elaboró sin quebrantar ni suplantar los derechos de autor de terceros, y de tal forma, la obra es de su exclusiva autoría y tiene la titularidad sobre éste. PARÁGRAFO: en caso de queja o acción por parte de un tercero referente a los derechos de autor sobre el artículo, folleto o libro en cuestión, EL AUTOR, asumirá la responsabilidad total, y saldrá en defensa de los derechos aquí autorizados; para todos los efectos, la Universidad Icesi actúa como un tercero de buena fe. Esta autorización, permite a la Universidad Icesi, de forma indefinida, para que en los términos establecidos en la Ley 23 de 1982, la Ley 44 de 1993, leyes y jurisprudencia vigente al respecto, haga publicación de este con fines educativos. Toda persona que consulte ya sea la biblioteca o en medio electrónico podrá copiar apartes del texto citando siempre la fuentes, es decir el título del trabajo y el autor.https://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessAtribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)http://purl.org/coar/access_right/c_abf2Ciencias socio biomédicasMedical sciencesColitis colagenosaTrasplanteEnfermedades intestinales inflamatoriasCollagenous Colitis-like Condition in Immunosuppressed Infant Baboonsinfo:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_2df8fbb1Artículoinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85Comunidad Universidad Icesi – Investigadores13251332ORIGINALecheverri_collagenous_colitis_2012.pdfecheverri_collagenous_colitis_2012.pdfapplication/pdf650356http://repository.icesi.edu.co/biblioteca_digital/bitstream/10906/81191/1/echeverri_collagenous_colitis_2012.pdf789121c7abfc97b6b28c637c4b24d69cMD5110906/81191oai:repository.icesi.edu.co:10906/811912018-10-08 14:04:34.162Biblioteca Digital - Universidad icesicdcriollo@icesi.edu.co |
dc.title.spa.fl_str_mv |
Collagenous Colitis-like Condition in Immunosuppressed Infant Baboons |
title |
Collagenous Colitis-like Condition in Immunosuppressed Infant Baboons |
spellingShingle |
Collagenous Colitis-like Condition in Immunosuppressed Infant Baboons Ciencias socio biomédicas Medical sciences Colitis colagenosa Trasplante Enfermedades intestinales inflamatorias |
title_short |
Collagenous Colitis-like Condition in Immunosuppressed Infant Baboons |
title_full |
Collagenous Colitis-like Condition in Immunosuppressed Infant Baboons |
title_fullStr |
Collagenous Colitis-like Condition in Immunosuppressed Infant Baboons |
title_full_unstemmed |
Collagenous Colitis-like Condition in Immunosuppressed Infant Baboons |
title_sort |
Collagenous Colitis-like Condition in Immunosuppressed Infant Baboons |
dc.creator.fl_str_mv |
Montoya, Claudia L. Wágner, Róbert A. Wolf, Roman F. Klein, Edwin C. Rigatti, Lora H. Dons, Eefje M. Echeverri Junca, Gabriel Jaime Cooper, David KC C. Ijzermans, Jan Nicolaas Maria |
dc.contributor.author.spa.fl_str_mv |
Montoya, Claudia L. Wágner, Róbert A. Wolf, Roman F. Klein, Edwin C. Rigatti, Lora H. Dons, Eefje M. Echeverri Junca, Gabriel Jaime Cooper, David KC C. Ijzermans, Jan Nicolaas Maria |
dc.subject.spa.fl_str_mv |
Ciencias socio biomédicas |
topic |
Ciencias socio biomédicas Medical sciences Colitis colagenosa Trasplante Enfermedades intestinales inflamatorias |
dc.subject.none.fl_str_mv |
Medical sciences Colitis colagenosa Trasplante Enfermedades intestinales inflamatorias |
description |
Collagenous colitis is a chronic inflammatory bowel disease of unknown etiology. It is fairly common in adult humans, but rare in infants, and has been associated with autoimmune disorders. METHODS We report four infant baboons (age 7-12 months) that had received a transplant at 3 months of age and subsequent immunosuppressive therapy for periods of 4-10 months. All presented identical symptoms within a period of 4 weeks, including weight loss associated with chronic watery diarrhea that was unresponsive to standard antimicrobial treatment. RESULTS Clinical chemistry evaluations were within normal ranges, viral causes were ruled out, and fecal and blood cultures were repeatedly negative. At necropsy, two infant baboons were found to have a form of collagenous colitis. In the remaining two baboons that had identical clinical features, immunosuppressive therapy was discontinued and treatment with budesonide was initiated. Both baboons recovered and remained well on no medication until the end of follow-up (24 months). |
publishDate |
2012 |
dc.date.issued.none.fl_str_mv |
2012-07-01 |
dc.date.accessioned.none.fl_str_mv |
2017-03-30T22:41:53Z |
dc.date.available.none.fl_str_mv |
2017-03-30T22:41:53Z |
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info:eu-repo/semantics/article |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
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Artículo |
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info:eu-repo/semantics/publishedVersion |
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http://purl.org/coar/version/c_970fb48d4fbd8a85 |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
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publishedVersion |
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1536-4844 |
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http://eds.a.ebscohost.com/eds/detail/detail?vid=1&sid=6f8503bc-d924-466a-b500-2aa885ed1a00%40sessionmgr4009&hid=4103&bdata=Jmxhbmc9ZXMmc2l0ZT1lZHMtbGl2ZSZzY29wZT1zaXRl#AN=edselc.2-52.0-84862236367&db=edselc http://www.pubmedcentral.nih.gov/articlerender. |
dc.identifier.uri.none.fl_str_mv |
http://hdl.handle.net/10906/81191 |
dc.identifier.doi.none.fl_str_mv |
http://dx.doi.org/10.1002/ibd.21900 |
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instname: Universidad Icesi |
dc.identifier.reponame.none.fl_str_mv |
reponame: Biblioteca Digital |
dc.identifier.repourl.none.fl_str_mv |
repourl: https://repository.icesi.edu.co/ |
identifier_str_mv |
1536-4844 instname: Universidad Icesi reponame: Biblioteca Digital repourl: https://repository.icesi.edu.co/ |
url |
http://eds.a.ebscohost.com/eds/detail/detail?vid=1&sid=6f8503bc-d924-466a-b500-2aa885ed1a00%40sessionmgr4009&hid=4103&bdata=Jmxhbmc9ZXMmc2l0ZT1lZHMtbGl2ZSZzY29wZT1zaXRl#AN=edselc.2-52.0-84862236367&db=edselc http://www.pubmedcentral.nih.gov/articlerender. http://hdl.handle.net/10906/81191 http://dx.doi.org/10.1002/ibd.21900 |
dc.language.iso.spa.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.none.fl_str_mv |
Inflammatory Bowel Diseases, Vol. 18,No. 7 - 2012 |
dc.rights.uri.none.fl_str_mv |
https://creativecommons.org/licenses/by-nc-nd/4.0/ |
dc.rights.accessrights.none.fl_str_mv |
info:eu-repo/semantics/openAccess |
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Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0) |
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http://purl.org/coar/access_right/c_abf2 |
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https://creativecommons.org/licenses/by-nc-nd/4.0/ Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0) http://purl.org/coar/access_right/c_abf2 |
eu_rights_str_mv |
openAccess |
dc.format.extent.none.fl_str_mv |
7 páginas |
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Digital |
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application/pdf |
dc.coverage.spatial.none.fl_str_mv |
New Jersey de Coordinates: Lat: 40 00 00 N degrees minutes Lat: 40.0000 decimal degrees Long: 075 00 00 W degrees minutes Long: -75.0000 decimal degrees |
dc.publisher.none.fl_str_mv |
Wiley |
dc.publisher.faculty.none.fl_str_mv |
Facultad Ciencias de la Salud |
dc.publisher.program.none.fl_str_mv |
Medicina |
dc.publisher.department.none.fl_str_mv |
Departamento de Ciencias Básicas Médicas |
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New Jersey |
publisher.none.fl_str_mv |
Wiley |
institution |
Universidad ICESI |
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