B lymphocytes: development, tolerance, and their role in autoimmunity-focus on systemic lupus erythematosus.

B lymphocytes are the effectors of humoral immunity, providing defense against pathogens through different functions including antibody production. B cells constitute approximately 15% of peripheral blood leukocytes and arise from hemopoietic stem cells in the bone marrow. It is here that their anti...

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Autores:
Cañas Dávila, Carlos Alberto
Tipo de recurso:
Revisión
Fecha de publicación:
2013
Institución:
Universidad ICESI
Repositorio:
Repositorio ICESI
Idioma:
eng
OAI Identifier:
oai:repository.icesi.edu.co:10906/78351
Acceso en línea:
http://www.scopus.com/inward/record.url?eid=2-s2.0-84885613949&partnerID=tZOtx3y1
http://hdl.handle.net/10906/78351
http://dx.doi.org/10.1155/2013/827254
Palabra clave:
Autoinmunidad
Linfocitos
Enfermedades autoinmunes
Ciencias socio biomédicas
Lupus
Medical sciences
Rights
openAccess
License
http://purl.org/coar/access_right/c_abf2
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oai_identifier_str oai:repository.icesi.edu.co:10906/78351
network_acronym_str ICESI2
network_name_str Repositorio ICESI
repository_id_str
spelling Cañas Dávila, Carlos AlbertoAmsterdam de Lat: 52 21 00 N degrees minutes Lat: 52.3500 decimal degrees Long: 004 55 00 E degrees minutes Long: 4.9167 decimal degrees2015-10-02T21:02:12Z2015-10-02T21:02:12Z2013-01-010896-8411http://www.scopus.com/inward/record.url?eid=2-s2.0-84885613949&partnerID=tZOtx3y1http://hdl.handle.net/10906/78351http://dx.doi.org/10.1155/2013/827254instname: Universidad Icesireponame: Biblioteca Digitalrepourl: https://repository.icesi.edu.co/B lymphocytes are the effectors of humoral immunity, providing defense against pathogens through different functions including antibody production. B cells constitute approximately 15% of peripheral blood leukocytes and arise from hemopoietic stem cells in the bone marrow. It is here that their antigen receptors (surface immunoglobulin) are assembled. In the context of autoimmune diseases defined by B and/or T cell autoreactive that upon activation lead to chronic tissue inflammation and often irreversible structural and functional damage, B lymphocytes play an essential role by not only producing autoantibodies but also functioning as antigen-presenting cells (APC) and as a source of cytokines. In this paper, we describe B lymphocyte functions in autoimmunity and autoimmune diseases with a special focus on their abnormalities in systemic lupus erythematosus.[Sin paginación]Digitalapplication/pdfengElsevierFacultad Ciencias de la SaludMedicinaDepartamento de Ciencias Básicas MédicasAmsterdamAutoimmune Diseases, Vol, 2013 - 2013EL AUTOR, expresa que la obra objeto de la presente autorización es original y la elaboró sin quebrantar ni suplantar los derechos de autor de terceros, y de tal forma, la obra es de su exclusiva autoría y tiene la titularidad sobre éste. PARÁGRAFO: en caso de queja o acción por parte de un tercero referente a los derechos de autor sobre el artículo, folleto o libro en cuestión, EL AUTOR, asumirá la responsabilidad total, y saldrá en defensa de los derechos aquí autorizados; para todos los efectos, la Universidad Icesi actúa como un tercero de buena fe. Esta autorización, permite a la Universidad Icesi, de forma indefinida, para que en los términos establecidos en la Ley 23 de 1982, la Ley 44 de 1993, leyes y jurisprudencia vigente al respecto, haga publicación de este con fines educativos. Toda persona que consulte ya sea la biblioteca o en medio electrónico podrá copiar apartes del texto citando siempre la fuentes, es decir el título del trabajo y el autor.info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2AutoinmunidadLinfocitosEnfermedades autoinmunesCiencias socio biomédicasLupusMedical sciencesB lymphocytes: development, tolerance, and their role in autoimmunity-focus on systemic lupus erythematosus.info:eu-repo/semantics/reviewhttp://purl.org/coar/resource_type/c_efa0Revisióninfo:eu-repo/semantics/submittedVersionhttp://purl.org/coar/version/c_71e4c1898caa6e32Comunidad Universidad Icesi – Investigadores2013ORIGINALdocumento.htmldocumento.htmltext/html283http://repository.icesi.edu.co/biblioteca_digital/bitstream/10906/78351/1/documento.html90d3efb0f83fba8643f784cb5ed8966bMD5110906/78351oai:repository.icesi.edu.co:10906/783512018-10-01 11:20:26.871Biblioteca Digital - Universidad icesicdcriollo@icesi.edu.co
dc.title.spa.fl_str_mv B lymphocytes: development, tolerance, and their role in autoimmunity-focus on systemic lupus erythematosus.
title B lymphocytes: development, tolerance, and their role in autoimmunity-focus on systemic lupus erythematosus.
spellingShingle B lymphocytes: development, tolerance, and their role in autoimmunity-focus on systemic lupus erythematosus.
Autoinmunidad
Linfocitos
Enfermedades autoinmunes
Ciencias socio biomédicas
Lupus
Medical sciences
title_short B lymphocytes: development, tolerance, and their role in autoimmunity-focus on systemic lupus erythematosus.
title_full B lymphocytes: development, tolerance, and their role in autoimmunity-focus on systemic lupus erythematosus.
title_fullStr B lymphocytes: development, tolerance, and their role in autoimmunity-focus on systemic lupus erythematosus.
title_full_unstemmed B lymphocytes: development, tolerance, and their role in autoimmunity-focus on systemic lupus erythematosus.
title_sort B lymphocytes: development, tolerance, and their role in autoimmunity-focus on systemic lupus erythematosus.
dc.creator.fl_str_mv Cañas Dávila, Carlos Alberto
dc.contributor.author.spa.fl_str_mv Cañas Dávila, Carlos Alberto
dc.subject.spa.fl_str_mv Autoinmunidad
Linfocitos
Enfermedades autoinmunes
Ciencias socio biomédicas
topic Autoinmunidad
Linfocitos
Enfermedades autoinmunes
Ciencias socio biomédicas
Lupus
Medical sciences
dc.subject.none.fl_str_mv Lupus
dc.subject.eng.fl_str_mv Medical sciences
description B lymphocytes are the effectors of humoral immunity, providing defense against pathogens through different functions including antibody production. B cells constitute approximately 15% of peripheral blood leukocytes and arise from hemopoietic stem cells in the bone marrow. It is here that their antigen receptors (surface immunoglobulin) are assembled. In the context of autoimmune diseases defined by B and/or T cell autoreactive that upon activation lead to chronic tissue inflammation and often irreversible structural and functional damage, B lymphocytes play an essential role by not only producing autoantibodies but also functioning as antigen-presenting cells (APC) and as a source of cytokines. In this paper, we describe B lymphocyte functions in autoimmunity and autoimmune diseases with a special focus on their abnormalities in systemic lupus erythematosus.
publishDate 2013
dc.date.issued.none.fl_str_mv 2013-01-01
dc.date.accessioned.none.fl_str_mv 2015-10-02T21:02:12Z
dc.date.available.none.fl_str_mv 2015-10-02T21:02:12Z
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dc.identifier.instname.none.fl_str_mv instname: Universidad Icesi
dc.identifier.reponame.none.fl_str_mv reponame: Biblioteca Digital
dc.identifier.repourl.none.fl_str_mv repourl: https://repository.icesi.edu.co/
identifier_str_mv 0896-8411
instname: Universidad Icesi
reponame: Biblioteca Digital
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url http://www.scopus.com/inward/record.url?eid=2-s2.0-84885613949&partnerID=tZOtx3y1
http://hdl.handle.net/10906/78351
http://dx.doi.org/10.1155/2013/827254
dc.language.iso.eng.fl_str_mv eng
language eng
dc.relation.ispartof.none.fl_str_mv Autoimmune Diseases, Vol, 2013 - 2013
dc.rights.accessrights.eng.fl_str_mv info:eu-repo/semantics/openAccess
dc.rights.coar.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
rights_invalid_str_mv http://purl.org/coar/access_right/c_abf2
dc.format.extent.none.fl_str_mv [Sin paginación]
dc.format.medium.spa.fl_str_mv Digital
dc.format.mimetype.none.fl_str_mv application/pdf
dc.coverage.spatial.none.fl_str_mv Amsterdam de Lat: 52 21 00 N degrees minutes Lat: 52.3500 decimal degrees Long: 004 55 00 E degrees minutes Long: 4.9167 decimal degrees
dc.publisher.none.fl_str_mv Elsevier
dc.publisher.faculty.spa.fl_str_mv Facultad Ciencias de la Salud
dc.publisher.program.none.fl_str_mv Medicina
dc.publisher.department.spa.fl_str_mv Departamento de Ciencias Básicas Médicas
dc.publisher.place.none.fl_str_mv Amsterdam
publisher.none.fl_str_mv Elsevier
institution Universidad ICESI
bitstream.url.fl_str_mv http://repository.icesi.edu.co/biblioteca_digital/bitstream/10906/78351/1/documento.html
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repository.name.fl_str_mv Biblioteca Digital - Universidad icesi
repository.mail.fl_str_mv cdcriollo@icesi.edu.co
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