Pathophysiological Relationship between Infections and Systemic Vasculitis.

The development of autoimmune disorders requires a combination of genetic, immunological, and environmental factors. Infectious agents, such as viruses and bacteria, can trigger autoimmunity through different mechanisms, and for systemic vasculitis in particular, microbial agents have been suggested to be involved in its pathogenesis. Although the exact mechanisms have not been fully elucidated, different theories have been postulated. This review considers the role of infections in the etiology of primary vasculitis, emphasizing their related immunological events.

• Autores: Muñoz Grajales, Carolina; Pineda, Juan C
• Tipo de recurso: Revisión
• Fecha de publicación: 2015
• Institución: Universidad ICESI
• Repositorio: Repositorio ICESI
• Idioma: eng
• OAI Identifier: oai:repository.icesi.edu.co:10906/82222
• Acceso en línea: http://www.ncbi.nlm.nih.gov/pubmed/26236499; http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=PMC4508375; http://hdl.handle.net/10906/82222; http://dx.doi.org/10.1155/2015/286783
• Palabra clave: Ciencias socio biomédicas; Vasculitis; Sistema inmune; Enfermedades autoinmunes; Fisiopatología; Medical sciences
• Rights: openAccess
• License: http://purl.org/coar/access_right/c_abf2