Toxic Epidermal Necrolysis Successfully Treated With Infliximab

Toxic epidermal necrolysis (TEN) is a life-threatening drug-induced cutaneous reaction characterized by widespread apoptosis and detachment of the epidermis. The main causes of death are secondary infections resulting from epidermal damage and multiorgan failure [1]. The severity of illness score (S...

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Autores:
Ramírez Escobar, Andrés Felipe
Serrano Reyes, Carlos Daniel
Tipo de recurso:
Article of investigation
Fecha de publicación:
2013
Institución:
Universidad ICESI
Repositorio:
Repositorio ICESI
Idioma:
eng
OAI Identifier:
oai:repository.icesi.edu.co:10906/81261
Acceso en línea:
http://nebulosa.icesi.edu.co:2143/full_record.do?product=WOS&search_mode=GeneralSearch&qid=13&SID=2FC4SXeHQQuQBhwxKyC&page=1&doc=2
http://hdl.handle.net/10906/81261
Palabra clave:
Dermatosis
Ciencias socio biomédicas
Necrólisis epidérmica tóxica
Factor de necrosis tumoral
Alergía
Medical sciences
Rights
openAccess
License
https://creativecommons.org/licenses/by-nc-nd/4.0/
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oai_identifier_str oai:repository.icesi.edu.co:10906/81261
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network_name_str Repositorio ICESI
repository_id_str
spelling Ramírez Escobar, Andrés FelipeSerrano Reyes, Carlos Danielcd_serrano@yahoo.com2017-03-30T22:42:07Z2017-03-30T22:42:07Z2013-01-011018-9068http://nebulosa.icesi.edu.co:2143/full_record.do?product=WOS&search_mode=GeneralSearch&qid=13&SID=2FC4SXeHQQuQBhwxKyC&page=1&doc=2http://hdl.handle.net/10906/81261instname: Universidad Icesireponame: Biblioteca Digitalrepourl: https://repository.icesi.edu.co/Toxic epidermal necrolysis (TEN) is a life-threatening drug-induced cutaneous reaction characterized by widespread apoptosis and detachment of the epidermis. The main causes of death are secondary infections resulting from epidermal damage and multiorgan failure [1]. The severity of illness score (SCORTEN) [2] analyzes 7 independent risk factors and predicts mortality. Older age, significant comorbidity, and greater skin involvement correlate with a worse prognosis [2]. The pathogenesis of TEN is unknown. Several studies suggest that tumor necrosis factor (TNF) α released from inflammatory cells and activated keratinocytes in the epidermis plays an important role in the immune response by inducing direct cytotoxicity and apoptosis [3].3 páginasDigitalapplication/pdfengEsmon Publicidad S A,Facultad Ciencias de la SaludMedicinaBarcelonaDepartamento de Ciencias Básicas MédicasBarcelona de Lat: 41 40 00 N degrees minutes Lat: 41.6660 decimal degrees Long: 002 00 00 E degrees minutes Long: 2.0000 decimal degreesJournal of investigational Allergology and Clinical Immunology, Vol. 23, 1 -2013EL AUTOR, expresa que la obra objeto de la presente autorización es original y la elaboró sin quebrantar ni suplantar los derechos de autor de terceros, y de tal forma, la obra es de su exclusiva autoría y tiene la titularidad sobre éste. PARÁGRAFO: en caso de queja o acción por parte de un tercero referente a los derechos de autor sobre el artículo, folleto o libro en cuestión, EL AUTOR, asumirá la responsabilidad total, y saldrá en defensa de los derechos aquí autorizados; para todos los efectos, la Universidad Icesi actúa como un tercero de buena fe. Esta autorización, permite a la Universidad Icesi, de forma indefinida, para que en los términos establecidos en la Ley 23 de 1982, la Ley 44 de 1993, leyes y jurisprudencia vigente al respecto, haga publicación de este con fines educativos. Toda persona que consulte ya sea la biblioteca o en medio electrónico podrá copiar apartes del texto citando siempre la fuentes, es decir el título del trabajo y el autor.https://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessAtribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)http://purl.org/coar/access_right/c_abf2DermatosisCiencias socio biomédicasNecrólisis epidérmica tóxicaFactor de necrosis tumoralAlergíaMedical sciencesToxic Epidermal Necrolysis Successfully Treated With Infliximabinfo:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_2df8fbb1Artículoinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85Comunidad Universidad Icesi – Investigadores2316163ORIGINALdocumento.htmldocumento.htmltext/html929http://repository.icesi.edu.co/biblioteca_digital/bitstream/10906/81261/1/documento.html5b95824c5cfd42d6e0a3735d391bfc6fMD5110906/81261oai:repository.icesi.edu.co:10906/812612020-05-21 08:50:04.54Biblioteca Digital - Universidad icesicdcriollo@icesi.edu.co
dc.title.spa.fl_str_mv Toxic Epidermal Necrolysis Successfully Treated With Infliximab
title Toxic Epidermal Necrolysis Successfully Treated With Infliximab
spellingShingle Toxic Epidermal Necrolysis Successfully Treated With Infliximab
Dermatosis
Ciencias socio biomédicas
Necrólisis epidérmica tóxica
Factor de necrosis tumoral
Alergía
Medical sciences
title_short Toxic Epidermal Necrolysis Successfully Treated With Infliximab
title_full Toxic Epidermal Necrolysis Successfully Treated With Infliximab
title_fullStr Toxic Epidermal Necrolysis Successfully Treated With Infliximab
title_full_unstemmed Toxic Epidermal Necrolysis Successfully Treated With Infliximab
title_sort Toxic Epidermal Necrolysis Successfully Treated With Infliximab
dc.creator.fl_str_mv Ramírez Escobar, Andrés Felipe
Serrano Reyes, Carlos Daniel
dc.contributor.author.spa.fl_str_mv Ramírez Escobar, Andrés Felipe
Serrano Reyes, Carlos Daniel
dc.subject.spa.fl_str_mv Dermatosis
Ciencias socio biomédicas
Necrólisis epidérmica tóxica
Factor de necrosis tumoral
Alergía
topic Dermatosis
Ciencias socio biomédicas
Necrólisis epidérmica tóxica
Factor de necrosis tumoral
Alergía
Medical sciences
dc.subject.eng.fl_str_mv Medical sciences
description Toxic epidermal necrolysis (TEN) is a life-threatening drug-induced cutaneous reaction characterized by widespread apoptosis and detachment of the epidermis. The main causes of death are secondary infections resulting from epidermal damage and multiorgan failure [1]. The severity of illness score (SCORTEN) [2] analyzes 7 independent risk factors and predicts mortality. Older age, significant comorbidity, and greater skin involvement correlate with a worse prognosis [2]. The pathogenesis of TEN is unknown. Several studies suggest that tumor necrosis factor (TNF) α released from inflammatory cells and activated keratinocytes in the epidermis plays an important role in the immune response by inducing direct cytotoxicity and apoptosis [3].
publishDate 2013
dc.date.issued.none.fl_str_mv 2013-01-01
dc.date.accessioned.none.fl_str_mv 2017-03-30T22:42:07Z
dc.date.available.none.fl_str_mv 2017-03-30T22:42:07Z
dc.type.eng.fl_str_mv info:eu-repo/semantics/article
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dc.type.local.spa.fl_str_mv Artículo
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dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/10906/81261
dc.identifier.instname.none.fl_str_mv instname: Universidad Icesi
dc.identifier.reponame.none.fl_str_mv reponame: Biblioteca Digital
dc.identifier.repourl.none.fl_str_mv repourl: https://repository.icesi.edu.co/
identifier_str_mv 1018-9068
instname: Universidad Icesi
reponame: Biblioteca Digital
repourl: https://repository.icesi.edu.co/
url http://nebulosa.icesi.edu.co:2143/full_record.do?product=WOS&search_mode=GeneralSearch&qid=13&SID=2FC4SXeHQQuQBhwxKyC&page=1&doc=2
http://hdl.handle.net/10906/81261
dc.language.iso.eng.fl_str_mv eng
language eng
dc.relation.ispartof.eng.fl_str_mv Journal of investigational Allergology and Clinical Immunology, Vol. 23, 1 -2013
dc.rights.uri.none.fl_str_mv https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.accessrights.none.fl_str_mv info:eu-repo/semantics/openAccess
dc.rights.license.none.fl_str_mv Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)
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Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)
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eu_rights_str_mv openAccess
dc.format.extent.spa.fl_str_mv 3 páginas
dc.format.medium.spa.fl_str_mv Digital
dc.format.mimetype.none.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Esmon Publicidad S A,
dc.publisher.faculty.spa.fl_str_mv Facultad Ciencias de la Salud
dc.publisher.program.spa.fl_str_mv Medicina
dc.publisher.place.spa.fl_str_mv Barcelona
Departamento de Ciencias Básicas Médicas
dc.publisher.place.none.fl_str_mv Barcelona de Lat: 41 40 00 N degrees minutes Lat: 41.6660 decimal degrees Long: 002 00 00 E degrees minutes Long: 2.0000 decimal degrees
institution Universidad ICESI
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