Rituximab for Remission Induction and Maintenance in Refractory Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease with high morbidity if untreated. Sometimes, despite aggressive treatments, the disease remains active with cumulative organic damage. We conducted a retrospective and descriptive observational study of patients with SLE...

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Autores:
Echeverri, Andrés Felipe
Cañas Dávila, Carlos Alberto
Tipo de recurso:
Article of investigation
Fecha de publicación:
2014
Institución:
Universidad ICESI
Repositorio:
Repositorio ICESI
Idioma:
eng
OAI Identifier:
oai:repository.icesi.edu.co:10906/78485
Acceso en línea:
http://www.scopus.com/inward/record.url?eid=2-s2.0-84893658088&partnerID=tZOtx3y1
http://hdl.handle.net/10906/78485
http://dx.doi.org/10.1155/2014/731806
Palabra clave:
Lupus eritematoso sistémico
Enfermedad Inflamatoria
Enfermedades autoinmunes
Rights
openAccess
License
https://creativecommons.org/licenses/by-nc-nd/4.0/
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oai_identifier_str oai:repository.icesi.edu.co:10906/78485
network_acronym_str ICESI2
network_name_str Repositorio ICESI
repository_id_str
spelling Echeverri, Andrés FelipeCañas Dávila, Carlos AlbertoAmsterdam de Lat: 52 21 00 N degrees minutes Lat: 52.3500 decimal degrees Long: 004 55 00 E degrees minutes Long: 4.9167 decimal degrees2015-10-13T21:06:03Z2015-10-13T21:06:03Z2014-01-010896-8411http://www.scopus.com/inward/record.url?eid=2-s2.0-84893658088&partnerID=tZOtx3y1http://hdl.handle.net/10906/78485http://dx.doi.org/10.1155/2014/731806instname: Universidad Icesireponame: Biblioteca Digitalrepourl: https://repository.icesi.edu.co/Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease with high morbidity if untreated. Sometimes, despite aggressive treatments, the disease remains active with cumulative organic damage. We conducted a retrospective and descriptive observational study of patients with SLE refractory to conventional treatment who were treated with rituximab (RTX) as remission induction therapy and maintenance. There was a significant reduction in the conventional immunosuppressive drug dose and the number of relapses of disease. RTX appeared to be effective and safe for the induction and maintenance of remission in patient with SLE refractory to conventional treatment. © 2014 Fabio Bonilla-Abadía et al.4 páginasDigitalapplication/pdfengElsevierÁmsterdamAutoimmune Diseases, Vo. 2014 - 2014EL AUTOR, expresa que la obra objeto de la presente autorización es original y la elaboró sin quebrantar ni suplantar los derechos de autor de terceros, y de tal forma, la obra es de su exclusiva autoría y tiene la titularidad sobre éste. PARÁGRAFO: en caso de queja o acción por parte de un tercero referente a los derechos de autor sobre el artículo, folleto o libro en cuestión, EL AUTOR, asumirá la responsabilidad total, y saldrá en defensa de los derechos aquí autorizados; para todos los efectos, la Universidad Icesi actúa como un tercero de buena fe. Esta autorización, permite a la Universidad Icesi, de forma indefinida, para que en los términos establecidos en la Ley 23 de 1982, la Ley 44 de 1993, leyes y jurisprudencia vigente al respecto, haga publicación de este con fines educativos. Toda persona que consulte ya sea la biblioteca o en medio electrónico podrá copiar apartes del texto citando siempre la fuentes, es decir el título del trabajo y el autor.https://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessAtribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)http://purl.org/coar/access_right/c_abf2Lupus eritematoso sistémicoEnfermedad InflamatoriaEnfermedades autoinmunesRituximab for Remission Induction and Maintenance in Refractory Systemic Lupus Erythematosusinfo:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_2df8fbb1Artículoinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85Comunidad Universidad Icesi – Investigadores201414ORIGINALecheverri_rituximab_remission_2014.pdfecheverri_rituximab_remission_2014.pdfapplication/pdf1238438http://repository.icesi.edu.co/biblioteca_digital/bitstream/10906/78485/1/echeverri_rituximab_remission_2014.pdf2bd59fd8be7aa7aeaadc9d84247af68fMD5110906/78485oai:repository.icesi.edu.co:10906/784852018-11-30 15:41:48.765Biblioteca Digital - Universidad icesicdcriollo@icesi.edu.co
dc.title.spa.fl_str_mv Rituximab for Remission Induction and Maintenance in Refractory Systemic Lupus Erythematosus
title Rituximab for Remission Induction and Maintenance in Refractory Systemic Lupus Erythematosus
spellingShingle Rituximab for Remission Induction and Maintenance in Refractory Systemic Lupus Erythematosus
Lupus eritematoso sistémico
Enfermedad Inflamatoria
Enfermedades autoinmunes
title_short Rituximab for Remission Induction and Maintenance in Refractory Systemic Lupus Erythematosus
title_full Rituximab for Remission Induction and Maintenance in Refractory Systemic Lupus Erythematosus
title_fullStr Rituximab for Remission Induction and Maintenance in Refractory Systemic Lupus Erythematosus
title_full_unstemmed Rituximab for Remission Induction and Maintenance in Refractory Systemic Lupus Erythematosus
title_sort Rituximab for Remission Induction and Maintenance in Refractory Systemic Lupus Erythematosus
dc.creator.fl_str_mv Echeverri, Andrés Felipe
Cañas Dávila, Carlos Alberto
dc.contributor.author.spa.fl_str_mv Echeverri, Andrés Felipe
Cañas Dávila, Carlos Alberto
dc.subject.none.fl_str_mv Lupus eritematoso sistémico
Enfermedad Inflamatoria
Enfermedades autoinmunes
topic Lupus eritematoso sistémico
Enfermedad Inflamatoria
Enfermedades autoinmunes
description Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease with high morbidity if untreated. Sometimes, despite aggressive treatments, the disease remains active with cumulative organic damage. We conducted a retrospective and descriptive observational study of patients with SLE refractory to conventional treatment who were treated with rituximab (RTX) as remission induction therapy and maintenance. There was a significant reduction in the conventional immunosuppressive drug dose and the number of relapses of disease. RTX appeared to be effective and safe for the induction and maintenance of remission in patient with SLE refractory to conventional treatment. © 2014 Fabio Bonilla-Abadía et al.
publishDate 2014
dc.date.issued.none.fl_str_mv 2014-01-01
dc.date.accessioned.none.fl_str_mv 2015-10-13T21:06:03Z
dc.date.available.none.fl_str_mv 2015-10-13T21:06:03Z
dc.type.eng.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/10906/78485
dc.identifier.doi.none.fl_str_mv http://dx.doi.org/10.1155/2014/731806
dc.identifier.instname.none.fl_str_mv instname: Universidad Icesi
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url http://www.scopus.com/inward/record.url?eid=2-s2.0-84893658088&partnerID=tZOtx3y1
http://hdl.handle.net/10906/78485
http://dx.doi.org/10.1155/2014/731806
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.ispartof.none.fl_str_mv Autoimmune Diseases, Vo. 2014 - 2014
dc.rights.uri.none.fl_str_mv https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.accessrights.spa.fl_str_mv info:eu-repo/semantics/openAccess
dc.rights.license.none.fl_str_mv Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)
dc.rights.coar.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/4.0/
Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.extent.none.fl_str_mv 4 páginas
dc.format.medium.none.fl_str_mv Digital
dc.format.mimetype.none.fl_str_mv application/pdf
dc.coverage.spatial.none.fl_str_mv Amsterdam de Lat: 52 21 00 N degrees minutes Lat: 52.3500 decimal degrees Long: 004 55 00 E degrees minutes Long: 4.9167 decimal degrees
dc.publisher.none.fl_str_mv Elsevier
dc.publisher.place.none.fl_str_mv Ámsterdam
publisher.none.fl_str_mv Elsevier
institution Universidad ICESI
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