Effects of fluids on microvascular perfusion in patients with severe sepsis
Purpose To evaluate the effects of fluid administration on microcirculatory alterations in sepsis. Methods With a Sidestream Dark Field device, we evaluated the effects of fluids on the sublingual microcirculation in 60 patients with severe sepsis. These patients were investigated either within 24 h...
- Autores:
-
Ospina Tascón, Gustavo Adolfo
Backer, Daniel De
Vincent, Jean Louis
Fonseca, Adriana
Oliveira Silva, Tatiana
Chierego, Maria Luisa
Simion, Davide
Büchele, Gustavo
Donadello, Katia
Occhipinti, Giovanna
Neves, Ana Paula
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2010
- Institución:
- Universidad ICESI
- Repositorio:
- Repositorio ICESI
- Idioma:
- eng
- OAI Identifier:
- oai:repository.icesi.edu.co:10906/81205
- Palabra clave:
- Microcirculación
Coloides
Cristaloides y coloides
Sepsis
- Rights
- openAccess
- License
- https://creativecommons.org/licenses/by-nc-nd/4.0/
| Summary: | Purpose To evaluate the effects of fluid administration on microcirculatory alterations in sepsis. Methods With a Sidestream Dark Field device, we evaluated the effects of fluids on the sublingual microcirculation in 60 patients with severe sepsis. These patients were investigated either within 24 h (early, n = 37) or more than 48 h (late, n = 23) after a diagnosis of severe sepsis. Hemodynamic and microcirculatory measurements were obtained before and 30 min after administration of 1,000 ml Ringer’s lactate (n = 29) or 400 ml 4% albumin (n = 31) solutions. |
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